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<script type="text/javascript" src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.boots.min.js"> </script><title>Mineral Oil - Drugs and Lactation Database (LactMed®) - NCBI Bookshelf</title>
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<meta name="citation_inbook_title" content="Drugs and Lactation Database (LactMed®) [Internet]">
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<meta name="citation_title" content="Mineral Oil">
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<meta name="citation_publisher" content="National Institute of Child Health and Human Development">
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<meta name="citation_date" content="2021/05/17">
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<meta name="citation_pmid" content="30000945">
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<meta name="citation_keywords" content="Petrogalar">
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<meta name="citation_keywords" content="Alboline">
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<meta name="citation_keywords" content="Blandlube">
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<meta name="citation_keywords" content="Crystosol">
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<meta name="citation_keywords" content="Fonoline">
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<meta name="citation_keywords" content="Kondremul">
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<meta name="citation_keywords" content="Paraffins">
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<meta name="citation_keywords" content="Paroleine">
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<meta name="citation_keywords" content="Peneteck">
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<meta name="citation_keywords" content="Perfecta">
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<meta name="citation_keywords" content="Protopet">
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<meta name="citation_keywords" content="Balneol">
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<meta name="citation_keywords" content="Drakeol">
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<meta name="citation_keywords" content="Penreco">
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<meta name="citation_keywords" content="Agoral">
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<meta name="citation_keywords" content="Glymol">
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<meta name="citation_keywords" content="Kaydol">
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<meta name="citation_keywords" content="Uvasol">
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<meta name="citation_keywords" content="Molol">
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<meta name="citation_keywords" content="Nujol">
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<meta name="citation_keywords" content="Parol">
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<meta name="citation_keywords" content="Saxol">
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<meta name="citation_keywords" content="Liquid paraffin">
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<meta name="citation_keywords" content="Liquid vaseline">
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<meta name="citation_keywords" content="Paraffinic oil">
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<meta name="citation_keywords" content="Paraffin oils">
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<meta name="citation_keywords" content="Adepsine oil">
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<meta name="citation_keywords" content="Mineral oils">
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<meta name="citation_keywords" content="Paraffin oil">
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<meta name="citation_keywords" content="Oil mineral">
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<meta name="citation_keywords" content="Oil,mineral">
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<meta name="citation_keywords" content="White oils">
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<meta name="citation_keywords" content="Coker gatch oil">
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<meta name="citation_keywords" content="Petrolatum, liq">
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<meta name="citation_keywords" content="White oil">
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<meta name="citation_keywords" content="Keri Lotion">
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<meta name="citation_keywords" content="Alpha Keri">
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<meta name="citation_keywords" content="Neo-Cultol">
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<meta name="citation_keywords" content="Liquid petrolatum">
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<meta name="citation_keywords" content="Mineral seal oil">
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<meta name="citation_keywords" content="Paraffin, liquid">
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<meta name="citation_keywords" content="Thermia C">
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<meta name="citation_keywords" content="USP mineral oil">
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<meta name="citation_keywords" content="Catenex OR">
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<meta name="citation_keywords" content="Primol D">
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<meta name="citation_keywords" content="Refresh PM">
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<meta name="citation_keywords" content="Heavy mineral oil">
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<meta name="citation_keywords" content="Jute batching oil">
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<meta name="citation_keywords" content="White mineral oil">
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<meta name="citation_keywords" content="Bayol F">
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<meta name="citation_keywords" content="Lacri-Lube NP">
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<meta name="citation_keywords" content="Carnation 70">
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<meta name="citation_keywords" content="Petrolatum, liquid">
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<meta name="citation_keywords" content="Mineral oil, pale">
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<meta name="citation_keywords" content="Oil mist, mineral">
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<meta name="citation_keywords" content="Ultrol 7">
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<meta name="citation_keywords" content="Haley's MO">
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<meta name="citation_keywords" content="Tech Pet F">
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<meta name="citation_keywords" content="Mineral oil, heavy">
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<meta name="citation_keywords" content="MagieSol 44">
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<meta name="citation_keywords" content="Shellflex 371N">
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<meta name="citation_keywords" content="Biobase 300">
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<meta name="citation_keywords" content="Caloria HT 43">
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<meta name="citation_keywords" content="Catenex 956">
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<meta name="citation_keywords" content="Clenvex AS 58">
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<meta name="citation_keywords" content="Cantenex SM 925">
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<meta name="citation_keywords" content="Bayol 55">
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<meta name="citation_keywords" content="Citgo 340 Neutral">
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<meta name="citation_keywords" content="Catenex P 491">
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<meta name="citation_keywords" content="Catenex P 941">
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<meta name="citation_keywords" content="Conosol C 200">
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<meta name="citation_keywords" content="Flexon 845">
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<meta name="citation_keywords" content="Paraffinic mineral oil">
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<meta name="citation_keywords" content="Primol 355">
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<meta name="citation_keywords" content="Sunpar 150">
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<meta name="citation_keywords" content="MINERAL OIL">
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<meta name="citation_keywords" content="Heavy liquid petrolatum">
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<meta name="citation_keywords" content="Lacri-Lube S.O.P.">
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<meta name="citation_keywords" content="Caswell No. 580AA">
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<meta name="citation_keywords" content="Mineral oil [Oil, misc.]">
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<meta name="citation_keywords" content="Aliphatic petroleum hydrocarbons">
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<meta name="citation_keywords" content="BVM 100N">
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<meta name="citation_keywords" content="HSDB 1922">
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<meta name="citation_keywords" content="EINECS 232-384-2">
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<meta name="citation_keywords" content="Mineral oil (saturated parrafin oil)">
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<meta name="citation_keywords" content="EPA Pesticide Chemical Code 063502">
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<meta name="citation_keywords" content="Mineral oil hydrocarbon solvent (petroleum)">
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<meta name="citation_keywords" content="EC 232-384-2">
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<meta name="citation_keywords" content="8012-95-1">
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<meta name="citation_keywords" content="Deobase">
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<meta name="citation_keywords" content="Mineral oils">
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<meta name="citation_keywords" content="Hydrocarbon oils">
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<meta name="citation_keywords" content="Mineral oil mist">
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<meta name="citation_keywords" content="Deodorized kerosene">
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<meta name="citation_keywords" content="Deodorized kerosine">
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<meta name="citation_keywords" content="Kerosene, deodorized">
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<meta name="citation_keywords" content="MINERAL OIL">
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<meta name="citation_keywords" content="CCRIS 8587">
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<meta name="citation_keywords" content="8020-83-5">
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<meta name="DC.Title" content="Mineral Oil">
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<meta name="DC.Type" content="Text">
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<meta name="DC.Publisher" content="National Institute of Child Health and Human Development">
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<meta name="DC.Date" content="2021/05/17">
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<meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK501885/">
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<meta name="description" content="Small amounts of mineral oil can be found in breastmilk, apparently from absorption of hydrocarbons from cosmetics over long periods of time. Because mineral oil is poorly absorbed orally, little or none will not reach the bloodstream of the infant or cause any adverse effects in breastfed infants.[1] One small study supports the lack of effect of maternal mineral oil on the bowels of their breastfed infants. Oral use of mineral oil by the nursing mother is acceptable, although repeated use should be avoided because it may cause a deficiency of fat-soluble vitamins. The use of mineral oil or ointments containing mineral oil on or near the breast may expose the infant to high levels of mineral paraffins via licking.[2] Only water-miscible cream products should be applied to the breast.">
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<meta name="og:title" content="Mineral Oil">
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<meta name="og:type" content="book">
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<meta name="og:description" content="Small amounts of mineral oil can be found in breastmilk, apparently from absorption of hydrocarbons from cosmetics over long periods of time. Because mineral oil is poorly absorbed orally, little or none will not reach the bloodstream of the infant or cause any adverse effects in breastfed infants.[1] One small study supports the lack of effect of maternal mineral oil on the bowels of their breastfed infants. Oral use of mineral oil by the nursing mother is acceptable, although repeated use should be avoided because it may cause a deficiency of fat-soluble vitamins. The use of mineral oil or ointments containing mineral oil on or near the breast may expose the infant to high levels of mineral paraffins via licking.[2] Only water-miscible cream products should be applied to the breast.">
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class="wsprkl btn" title="Jump to next match">▶</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><div class="fm-sec"><h1 id="_NBK501885_"><span class="title" itemprop="name">Mineral Oil</span></h1><p class="fm-aai"><a href="#_NBK501885_pubdet_">Publication Details</a></p><p><em>Estimated reading time: 2 minutes</em></p></div></div><div class="jig-ncbiinpagenav body-content whole_rhythm" data-jigconfig="allHeadingLevels: ['h2'],smoothScroll: false" itemprop="text"><p>CASRN: 8012-95-1; 8020-83-5</p><div id="LM966.Drug_Levels_and_Effects"><h2 id="_LM966_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM966.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>Small amounts of mineral oil can be found in breastmilk, apparently from absorption of hydrocarbons from cosmetics over long periods of time. Because mineral oil is poorly absorbed orally, little or none will not reach the bloodstream of the infant or cause any adverse effects in breastfed infants.[<a class="bibr" href="#LM966.REF.1" rid="LM966.REF.1">1</a>] One small study supports the lack of effect of maternal mineral oil on the bowels of their breastfed infants. Oral use of mineral oil by the nursing mother is acceptable, although repeated use should be avoided because it may cause a deficiency of fat-soluble vitamins. The use of mineral oil or ointments containing mineral oil on or near the breast may expose the infant to high levels of mineral paraffins via licking.[<a class="bibr" href="#LM966.REF.2" rid="LM966.REF.2">2</a>] Only water-miscible cream products should be applied to the breast.</p></div><div id="LM966.Drug_Levels"><h3>Drug Levels</h3><p><i>Maternal Levels.</i> In a study of women undergoing cesarean section, subcutaneous fat was removed to analyze it for mineral oil saturated hydrocarbons. Hindmilk was collected from some of the women on days 4 (n = 107) and 20 (n = 71) and also analyzed for these substances. The mean hydrocarbon content of milk fat on day 4 was 55 mg/kg of fat and on day 20 it was 15 mg/kg of fat. The amount in milk fat was correlated with the amount in subcutaneous fat. Based on questionnaires completed by the women, it appeared that the source of the hydrocarbons was accumulation over time from the application of cosmetics, such as sunscreen, hand cream and lipstick.[<a class="bibr" href="#LM966.REF.3" rid="LM966.REF.3">3</a>,<a class="bibr" href="#LM966.REF.4" rid="LM966.REF.4">4</a>]</p><p><i>Infant Levels.</i> Relevant published information was not found as of the revision date.</p></div><div id="LM966.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>Fifty mothers who were in the first day postpartum received 15 mL of either mineral oil or Magnolax (equivalent to 3.75 mL of mineral oil and 900 mg of magnesium hydroxide), although the exact number who received each product was not stated. Additional doses were given on subsequent days if needed. None of their breastfed infants were noted to have any markedly abnormal stools, although all of the infants also received supplemental feedings.[<a class="bibr" href="#LM966.REF.5" rid="LM966.REF.5">5</a>]</p></div><div id="LM966.Effects_on_Lactation_and_Breastmil"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM966.Alternate_Drugs_to_Consider"><h3>Alternate Drugs to Consider</h3><p>(Laxative) <a href="/books/n/lactmed/LM448/?report=reader">Bisacodyl</a>, <a href="/books/n/lactmed/LM463/?report=reader">Magnesium Hydroxide</a>, <a href="/books/n/lactmed/LM474/?report=reader">Senna</a></p></div><div id="LM966.References"><h3>References</h3><dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>1.</dt><dd><div class="bk_ref" id="LM966.REF.1">Hagemann TM. Gastrointestinal medications and breastfeeding. <span><span class="ref-journal">J Hum Lact. </span>1998;<span class="ref-vol">14</span>:259–62.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/10205441" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10205441</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>2.</dt><dd><div class="bk_ref" id="LM966.REF.2">Noti A, Grob K, Biedermann M, et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. <span><span class="ref-journal">Regul Toxicol Pharmacol. </span>2003;<span class="ref-vol">38</span>:317–25.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/14623482" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 14623482</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>3.</dt><dd><div class="bk_ref" id="LM966.REF.3">Concin N, Hofstetter G, Plattner B, et al. Mineral oil paraffins in human body fat and milk. <span><span class="ref-journal">Food Chem Toxicol. </span>2008;<span class="ref-vol">46</span>:544–52.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/17923223" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17923223</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>4.</dt><dd><div class="bk_ref" id="LM966.REF.4">Concin N, Hofstetter G, Plattner B, et al. Evidence for cosmetics as a source of mineral oil contamination in women. <span><span class="ref-journal">J Womens Health (Larchmt). </span>2011;<span class="ref-vol">20</span>:1713–9.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/21970597" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21970597</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>5.</dt><dd><div class="bk_ref" id="LM966.REF.5">Baldwin WF. Clinical study of senna administration to nursing mothers: Assessment of effects on infant bowel habits. <span><span class="ref-journal">Can Med Assoc J. </span>1963;<span class="ref-vol">89</span>:566–8.</span> [<a href="/pmc/articles/PMC1921820/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1921820</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/14045350" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 14045350</span></a>]</div></dd></dl></dl></div></div><div id="LM966.Substance_Identification"><h2 id="_LM966_Substance_Identification_">Substance Identification</h2><div id="LM966.Substance_Name"><h3>Substance Name</h3><p>Mineral Oil</p></div><div id="LM966.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>8012-95-1; 8020-83-5</p></div><div id="LM966.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Emollients</p><p>Gastrointestinal Agents</p><p>Laxatives</p></div></div><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></dl></div><div id="bk_toc_contnr"></div></div></div><div class="fm-sec"><h2 id="_NBK501885_pubdet_">Publication Details</h2><h3>Publication History</h3><p class="small">Last Revision: <span itemprop="dateModified">May 17, 2021</span>.</p><h3>Copyright</h3><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright Notice</a><p class="small"><b>Attribution Statement:</b> LactMed is a registered trademark of the U.S. Department of Health and Human Services.</p></div></div><h3>Publisher</h3><p><a href="https://www.nlm.nih.gov/" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">National Institute of Child Health and Human Development</a>, Bethesda (MD)</p><h3>NLM Citation</h3><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Mineral Oil. [Updated 2021 May 17].<span class="bk_cite_avail"></span></p></div><div class="small-screen-prev"><a href="/books/n/lactmed/LM703/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M75,30 c-80,60 -80,0 0,60 c-30,-60 -30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Prev</text></svg></a></div><div class="small-screen-next"><a href="/books/n/lactmed/LM183/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M25,30c80,60 80,0 0,60 c30,-60 30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Next</text></svg></a></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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