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<script type="text/javascript" src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.boots.min.js"> </script><title>Castor - Drugs and Lactation Database (LactMed®) - NCBI Bookshelf</title>
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<meta name="citation_inbook_title" content="Drugs and Lactation Database (LactMed®) [Internet]">
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<meta name="citation_title" content="Castor">
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<meta name="citation_publisher" content="National Institute of Child Health and Human Development">
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<meta name="citation_date" content="2024/12/15">
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<meta name="citation_pmid" content="30000935">
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<meta name="citation_fulltext_html_url" content="https://www.ncbi.nlm.nih.gov/books/NBK501875/">
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<meta name="citation_keywords" content="CASTOR OIL">
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<meta name="citation_keywords" content="Ricinus oil">
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<meta name="citation_keywords" content="Cosmetol">
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<meta name="citation_keywords" content="Phorbyol">
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<meta name="citation_keywords" content="Neoloid">
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<meta name="citation_keywords" content="Ricinol">
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<meta name="citation_keywords" content="Ricini oleum">
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<meta name="citation_keywords" content="Ricirus oil">
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<meta name="citation_keywords" content="Tangantangan oil">
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<meta name="citation_keywords" content="Oleum Ricini">
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<meta name="citation_keywords" content="Gold bond">
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<meta name="citation_keywords" content="Viscotrol C">
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<meta name="citation_keywords" content="Olio di ricino">
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<meta name="citation_keywords" content="Crystal O">
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<meta name="citation_keywords" content="Xenaderm">
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<meta name="citation_keywords" content="Venelex">
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<meta name="citation_keywords" content="Optase">
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<meta name="citation_keywords" content="Trypsin complex">
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<meta name="citation_keywords" content="Palma christi oil">
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<meta name="citation_keywords" content="DB Oil">
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<meta name="citation_keywords" content="Ricinus communis oil">
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<meta name="citation_keywords" content="LAVCO">
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<meta name="citation_keywords" content="Castor oil, aromatic">
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<meta name="citation_keywords" content="Oil of Palma christi">
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<meta name="citation_keywords" content="Caswell No. 165B">
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<meta name="citation_keywords" content="Olio di ricino [Italian]">
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<meta name="citation_keywords" content="UNII-D5340Y2I9G">
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<meta name="citation_keywords" content="FEMA No. 2263">
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<meta name="citation_keywords" content="CCRIS 4596">
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<meta name="citation_keywords" content="HSDB 1933">
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<meta name="citation_keywords" content="NCI-C55163">
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<meta name="citation_keywords" content="EINECS 232-293-8">
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<meta name="citation_keywords" content="D5340Y2I9G">
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<meta name="citation_keywords" content="EPA Pesticide Chemical Code 031608">
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<meta name="citation_keywords" content="African Coffee Tree">
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<meta name="citation_keywords" content="Arandi">
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<meta name="citation_keywords" content="Bi Ma Zi">
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<meta name="citation_keywords" content="Bofareira">
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<meta name="citation_keywords" content="Castorbean">
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<meta name="citation_keywords" content="Erand">
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<meta name="citation_keywords" content="Eranda">
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<meta name="citation_keywords" content="Gandharva Hasta">
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<meta name="citation_keywords" content="Graine de Ricin">
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<meta name="citation_keywords" content="Huile de Ricin">
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<meta name="citation_keywords" content="Huile de Ricin Végétale">
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<meta name="citation_keywords" content="Mexico Weed">
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<meta name="citation_keywords" content="Palma Christi">
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<meta name="citation_keywords" content="Ricin">
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<meta name="citation_keywords" content="Ricin Commun">
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<meta name="citation_keywords" content="Ricin Sanguin">
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<meta name="citation_keywords" content="Ricine">
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<meta name="citation_keywords" content="Ricino">
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<meta name="citation_keywords" content="Tangantangan Oil Plant">
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<meta name="citation_keywords" content="Wonder Tree">
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<link rel="schema.DC" href="http://purl.org/DC/elements/1.0/">
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<meta name="DC.Title" content="Castor">
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<meta name="DC.Type" content="Text">
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<meta name="DC.Publisher" content="National Institute of Child Health and Human Development">
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<meta name="DC.Date" content="2024/12/15">
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<meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK501875/">
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<meta name="description" content="Castor (Ricinus communis) beans contain triglycerides, mostly consisting of ricinoleic acid esters, and small amounts of the toxic ricin and ricine. Pressing of the beans produces castor oil and purification of the oil eliminates the ricin and ricine. Castor oil is a strong stimulant laxative. Castor beans as well as a homeopathic preparation of castor purportedly reduce milk flow,[1] but it is also reportedly used as a galactogogue.[2-4] A poultice of castor leaves is also a purported galactogogue.[5,6] In some parts of India, castor oil is also reportedly applied to the breasts to stimulate lactation.[6] No scientifically valid clinical trials support any of these uses and some preparations may be toxic to the infant. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[7,8] No data exist on the excretion of any components of the castor plant or castor oil into breastmilk or on their safety and efficacy in nursing mothers or infants. However, little of the active ricinoleic acid is thought to be absorbed from the intestine. Because of a lack of information, other cathartics may be preferred in nursing mothers.">
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<meta name="og:title" content="Castor">
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<meta name="og:type" content="book">
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<meta name="og:description" content="Castor (Ricinus communis) beans contain triglycerides, mostly consisting of ricinoleic acid esters, and small amounts of the toxic ricin and ricine. Pressing of the beans produces castor oil and purification of the oil eliminates the ricin and ricine. Castor oil is a strong stimulant laxative. Castor beans as well as a homeopathic preparation of castor purportedly reduce milk flow,[1] but it is also reportedly used as a galactogogue.[2-4] A poultice of castor leaves is also a purported galactogogue.[5,6] In some parts of India, castor oil is also reportedly applied to the breasts to stimulate lactation.[6] No scientifically valid clinical trials support any of these uses and some preparations may be toxic to the infant. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[7,8] No data exist on the excretion of any components of the castor plant or castor oil into breastmilk or on their safety and efficacy in nursing mothers or infants. However, little of the active ricinoleic acid is thought to be absorbed from the intestine. Because of a lack of information, other cathartics may be preferred in nursing mothers.">
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class="wsprkl btn" title="Jump to next match">▶</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><div class="fm-sec"><h1 id="_NBK501875_"><span class="title" itemprop="name">Castor</span></h1><p class="fm-aai"><a href="#_NBK501875_pubdet_">Publication Details</a></p><p><em>Estimated reading time: 2 minutes</em></p></div></div><div class="jig-ncbiinpagenav body-content whole_rhythm" data-jigconfig="allHeadingLevels: ['h2'],smoothScroll: false" itemprop="text"><p>CASRN: 8001-79-4</p><a href="https://pubchem.ncbi.nlm.nih.gov/substance/135279512" title="View this structure in PubChem" class="img_link" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubchem"><img src="https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&sid=135279512" alt="image 135279512 in the ncbi pubchem database" /></a><div id="LM957.Drug_Levels_and_Effects"><h2 id="_LM957_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM957.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>Castor (<i>Ricinus communis</i>) beans contain triglycerides, mostly consisting of ricinoleic acid esters, and small amounts of the toxic ricin and ricine. Pressing of the beans produces castor oil and purification of the oil eliminates the ricin and ricine. Castor oil is a strong stimulant laxative. Castor beans as well as a homeopathic preparation of castor purportedly reduce milk flow,[<a class="bibr" href="#LM957.REF.1" rid="LM957.REF.1">1</a>] but it is also reportedly used as a galactogogue.[<a class="bibr" href="#LM957.REF.2" rid="LM957.REF.2">2</a>-<a class="bibr" href="#LM957.REF.4" rid="LM957.REF.4">4</a>] A poultice of castor leaves is also a purported galactogogue.[<a class="bibr" href="#LM957.REF.5" rid="LM957.REF.5">5</a>,<a class="bibr" href="#LM957.REF.6" rid="LM957.REF.6">6</a>] In some parts of India, castor oil is also reportedly applied to the breasts to stimulate lactation.[<a class="bibr" href="#LM957.REF.6" rid="LM957.REF.6">6</a>] No scientifically valid clinical trials support any of these uses and some preparations may be toxic to the infant. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[<a class="bibr" href="#LM957.REF.7" rid="LM957.REF.7">7</a>,<a class="bibr" href="#LM957.REF.8" rid="LM957.REF.8">8</a>] No data exist on the excretion of any components of the castor plant or castor oil into breastmilk or on their safety and efficacy in nursing mothers or infants. However, little of the active ricinoleic acid is thought to be absorbed from the intestine. Because of a lack of information, other cathartics may be preferred in nursing mothers.</p><p>In traditional Indian culture, castor oil has been administered to newborn infants during the first 2 to 3 days of life, often resulting in adverse effects.[<a class="bibr" href="#LM957.REF.9" rid="LM957.REF.9">9</a>,<a class="bibr" href="#LM957.REF.10" rid="LM957.REF.10">10</a>] Administration of castor oil to newborns is dangerous and should be avoided.</p><p>Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to <i>prove</i> the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does <i>not</i> certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information <a href="/books/n/lactmed/LactMedDietarySupps/?report=reader">about dietary supplements</a> is available elsewhere on the LactMed Web site.</p></div><div id="LM957.Drug_Levels"><h3>Drug Levels</h3><p><i>Maternal Levels.</i> Relevant published information was not found as of the revision date.</p><p><i>Infant Levels.</i> Relevant published information was not found as of the revision date.</p></div><div id="LM957.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>In rural India, castor oil has been traditionally given to infants during the first 2 to 3 days of life to clear the intestine of meconium. This practice can result in paralytic ileus and aspiration pneumonia.[<a class="bibr" href="#LM957.REF.9" rid="LM957.REF.9">9</a>] Severe hypoalbuminemia was also reported in a 1.5-month-old infant whose grandmother gave him castor oil daily from the fifth day of life, resulting in diarrhea and malnutrition.[<a class="bibr" href="#LM957.REF.10" rid="LM957.REF.10">10</a>]</p></div><div id="LM957.Effects_on_Lactation_and_Breastmil"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM957.Alternate_Drugs_to_Consider"><h3>Alternate Drugs to Consider</h3><p>(Cathartic) <a href="/books/n/lactmed/LM448/?report=reader">Bisacodyl</a>, <a href="/books/n/lactmed/LM463/?report=reader">Magnesium Hydroxide</a>, <a href="/books/n/lactmed/LM474/?report=reader">Senna</a></p></div><div id="LM957.References"><h3>References</h3><dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>1.</dt><dd><div class="bk_ref" id="LM957.REF.1">Hardy
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M.
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Women's health series: Herbs of special interest to women.
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J Am Pharm Assoc (Wash)
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2000;40:234-42.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/10730024" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10730024</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>2.</dt><dd><div class="bk_ref" id="LM957.REF.2">Eglash
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A.
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Treatment of maternal hypergalactia.
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Breastfeed Med
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2014;9:423-5.
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[<a href="/pmc/articles/PMC4216483/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4216483</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25361472" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25361472</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>3.</dt><dd><div class="bk_ref" id="LM957.REF.3">Winterfeld
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U, Meyer
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Y, Panchaud
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A, et al.
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Management of deficient lactation in Switzerland and Canada: A survey of midwives' current practices.
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Breastfeed Med
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2012;7:317-8.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/22224508" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22224508</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>4.</dt><dd><div class="bk_ref" id="LM957.REF.4">Dandotiya
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H, Singh
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G, Kashaw
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S. The galactagogues use by Indian tribal communities to over come poor lactation.
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Int J Biotechnol Bioeng Res
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2013;4:243-8. <a href="http://www.ripublication.com/Volume/ijbbrv4n3spl.htm" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">http://www<wbr style="display:inline-block"></wbr>​.ripublication<wbr style="display:inline-block"></wbr>​.com/Volume/ijbbrv4n3spl.htm</a></div></dd></dl><dl class="bkr_refwrap"><dt>5.</dt><dd><div class="bk_ref" id="LM957.REF.5">Yarnell
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E.
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Botanical medicine in pregnancy and lactation.
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Altern Complement Ther
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1997;3 (April):93-100. doi:10.1089/act.1997.3.93 [<a href="http://dx.crossref.org/10.1089/act.1997.3.93" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></dd></dl><dl class="bkr_refwrap"><dt>6.</dt><dd><div class="bk_ref" id="LM957.REF.6">Rasiya
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B, A, Nayar
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T. Plants used for natal healthcare in folk medicine of Kerala, India.
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Indian J Tradit Knowl
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2011;10:523-7.</div></dd></dl><dl class="bkr_refwrap"><dt>7.</dt><dd><div class="bk_ref" id="LM957.REF.7">Brodribb W. ABM Clinical Protocol #9: Use of galactogogues in initiating or augmenting maternal milk production, second revision 2018.
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Breastfeed Med
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2018;13:307-14.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/29902083" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29902083</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>8.</dt><dd><div class="bk_ref" id="LM957.REF.8">Breastfeeding challenges: ACOG Committee Opinion, Number 820.
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Obstet Gynecol
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2021;137:e42-e53.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/33481531" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33481531</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>9.</dt><dd><div class="bk_ref" id="LM957.REF.9">Benakappa
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D, Raju
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M, Shivananda, et al. Breast-feeding practices in rural Karnataka (India) with special reference to lactation failure.
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Acta Paediatr Jpn
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1989;31:391-8.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/2514560" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 2514560</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>10.</dt><dd><div class="bk_ref" id="LM957.REF.10">Jayaprakash
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D, Raghu
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R, TS, Singh
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D, et al.
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Laxative induced hypoalbuminemia.
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Indian Pediatr
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1995;32:1037-8.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/8935275" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 8935275</span></a>]</div></dd></dl></dl></div></div><div id="LM957.Substance_Identification"><h2 id="_LM957_Substance_Identification_">Substance Identification</h2><div id="LM957.Substance_Name"><h3>Substance Name</h3><p>Castor</p></div><div id="LM957.Scientific_Name"><h3>Scientific Name</h3><p>Ricinus communis</p></div><div id="LM957.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>8001-79-4</p></div><div id="LM957.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Cathartics</p><p>Complementary Therapies</p><p>Oils</p><p>Phytotherapy</p><p>Plants, Medicinal</p></div></div><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></dl></div><div id="bk_toc_contnr"></div></div></div><div class="fm-sec"><h2 id="_NBK501875_pubdet_">Publication Details</h2><h3>Publication History</h3><p class="small">Last Revision: <span itemprop="dateModified">December 15, 2024</span>.</p><h3>Copyright</h3><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright Notice</a><p class="small"><b>Attribution Statement:</b> LactMed is a registered trademark of the U.S. Department of Health and Human Services.</p></div></div><h3>Publisher</h3><p><a href="https://www.nlm.nih.gov/" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">National Institute of Child Health and Human Development</a>, Bethesda (MD)</p><h3>NLM Citation</h3><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Castor. [Updated 2024 Dec 15].<span class="bk_cite_avail"></span></p></div><div class="small-screen-prev"><a href="/books/n/lactmed/LM875/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M75,30 c-80,60 -80,0 0,60 c-30,-60 -30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Prev</text></svg></a></div><div class="small-screen-next"><a href="/books/n/lactmed/cedazuridine/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M25,30c80,60 80,0 0,60 c30,-60 30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Next</text></svg></a></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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