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<meta name="robots" content="INDEX,FOLLOW,NOARCHIVE" /><meta name="citation_inbook_title" content="Drugs and Lactation Database (LactMed®) [Internet]" /><meta name="citation_title" content="Marshmallow" /><meta name="citation_publisher" content="National Institute of Child Health and Human Development" /><meta name="citation_date" content="2024/05/15" /><meta name="citation_pmid" content="30000899" /><meta name="citation_fulltext_html_url" content="https://www.ncbi.nlm.nih.gov/books/NBK501839/" /><meta name="citation_keywords" content="Marshmallow" /><meta name="citation_keywords" content="Althaea" /><meta name="citation_keywords" content="Mallow, Marsh" /><meta name="citation_keywords" content="Althaea officinalis" /><meta name="citation_keywords" content="Marsh Mallow (Althaea officinalis)" /><meta name="citation_keywords" content="EINECS 277-254-6" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Marshmallow" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="National Institute of Child Health and Human Development" /><meta name="DC.Date" content="2024/05/15" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK501839/" /><meta name="description" content="Marshmallow (Althaea officinalis) root contains polysaccharide mucilage composed L-rhamnose, D-galactose, D-galacturonic acid, and D-glucuronic acid. Topical marshmallow preparations have been advocated for treating sore, cracked nipples[1] and breast pain.[2] Orally, marshmallow is a purported galactogogue,[3,4] and is included in some proprietary mixtures promoted to increase milk supply; however, no scientifically valid clinical trials support this use. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[5,6] No data exist on the excretion of any components of marshmallow into breastmilk or on the safety and efficacy of marshmallow in nursing mothers or infants. Marshmallow is generally well tolerated in adults, with allergic reactions reported rarely. Marshmallow is "generally recognized as safe" (GRAS) in amounts found in foods by the U.S. Food and Drug Administration. Although no data exist on the safety of marshmallow root during breastfeeding, it is unlikely to be harmful to the breastfed infant." /><meta name="og:title" content="Marshmallow" /><meta name="og:type" content="book" /><meta name="og:description" content="Marshmallow (Althaea officinalis) root contains polysaccharide mucilage composed L-rhamnose, D-galactose, D-galacturonic acid, and D-glucuronic acid. Topical marshmallow preparations have been advocated for treating sore, cracked nipples[1] and breast pain.[2] Orally, marshmallow is a purported galactogogue,[3,4] and is included in some proprietary mixtures promoted to increase milk supply; however, no scientifically valid clinical trials support this use. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[5,6] No data exist on the excretion of any components of marshmallow into breastmilk or on the safety and efficacy of marshmallow in nursing mothers or infants. Marshmallow is generally well tolerated in adults, with allergic reactions reported rarely. Marshmallow is "generally recognized as safe" (GRAS) in amounts found in foods by the U.S. Food and Drug Administration. Although no data exist on the safety of marshmallow root during breastfeeding, it is unlikely to be harmful to the breastfed infant." /><meta name="og:url" content="https://www.ncbi.nlm.nih.gov/books/NBK501839/" /><meta name="og:site_name" content="NCBI Bookshelf" /><meta name="og:image" content="https://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-lactmed-lrg.png" /><meta name="twitter:card" content="summary" /><meta name="twitter:site" content="@ncbibooks" /><meta name="bk-non-canon-loc" content="/books/n/lactmed/LM924/" /><link rel="canonical" href="https://www.ncbi.nlm.nih.gov/books/NBK501839/" /><link rel="stylesheet" href="/corehtml/pmc/css/figpopup.css" type="text/css" media="screen" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books.min.css" type="text/css" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books_print.min.css" type="text/css" /><style type="text/css">p a.figpopup{display:inline !important} .bk_tt {font-family: monospace} .first-line-outdent .bk_ref {display: inline} </style><script type="text/javascript" src="/corehtml/pmc/js/jquery.hoverIntent.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/common.min.js?_=3.18"> </script><script type="text/javascript">window.name="mainwindow";</script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/book-toc.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/books.min.js"> </script>
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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. </p></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK501839_"><span class="title" itemprop="name">Marshmallow</span></h1><p class="small">Last Revision: <span itemprop="dateModified">May 15, 2024</span>.</p><p><em>Estimated reading time: 2 minutes</em></p></div><div class="body-content whole_rhythm" itemprop="text"><p>CASRN: 73049-65-7</p><div id="LM924.Drug_Levels_and_Effects"><h2 id="_LM924_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM924.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>Marshmallow (<i>Althaea officinalis</i>) root contains polysaccharide mucilage composed L-rhamnose, D-galactose, D-galacturonic acid, and D-glucuronic acid. Topical marshmallow preparations have been advocated for treating sore, cracked nipples[<a class="bk_pop" href="#LM924.REF.1">1</a>] and breast pain.[<a class="bk_pop" href="#LM924.REF.2">2</a>] Orally, marshmallow is a purported galactogogue,[<a class="bk_pop" href="#LM924.REF.3">3</a>,<a class="bk_pop" href="#LM924.REF.4">4</a>] and is included in some proprietary mixtures promoted to increase milk supply; however, no scientifically valid clinical trials support this use. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[<a class="bk_pop" href="#LM924.REF.5">5</a>,<a class="bk_pop" href="#LM924.REF.6">6</a>] No data exist on the excretion of any components of marshmallow into breastmilk or on the safety and efficacy of marshmallow in nursing mothers or infants. Marshmallow is generally well tolerated in adults, with allergic reactions reported rarely. Marshmallow is "generally recognized as safe" (GRAS) in amounts found in foods by the U.S. Food and Drug Administration. Although no data exist on the safety of marshmallow root during breastfeeding, it is unlikely to be harmful to the breastfed infant.</p><p>Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to <i>prove</i> the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does <i>not</i> certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information <a href="/books/n/lactmed/LactMedDietarySupps/">about dietary supplements</a> is available elsewhere on the LactMed Web site.</p></div><div id="LM924.Drug_Levels"><h3>Drug Levels</h3><p><i>Maternal Levels.</i> Relevant published information was not found as of the revision date.</p><p><i>Infant Levels.</i> Relevant published information was not found as of the revision date.</p></div><div id="LM924.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>A small manufacturer-sponsored, double-blind, randomized study compared Mother's Milk tea (Traditional Medicinals, Sebastopol, CA) to lemon verbena tea in exclusively breastfeeding mothers with milk insufficiency. Each Mother's Milk tea bag contained an unspecified amount of marshmallow root as well as several other herbs. Mothers were instructed to drink 3 to 5 cups of tea daily. No differences were seen between groups in infant digestive, respiratory, dermatological, and other maternal-reported adverse events. No differences were seen in the growth parameters of the breastfed infants between the two groups.[<a class="bk_pop" href="#LM924.REF.7">7</a>]</p></div><div id="LM924.Effects_on_Lactation_and_Breastmil"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM924.References"><h3>References</h3><dl class="temp-labeled-list"><dt>1.</dt><dd><div class="bk_ref" id="LM924.REF.1">Stapleton
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H.
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The use of herbal medicine in pregnancy and labour. Part II: Events after birth, including those affecting the health of babies.
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Complement Ther Nurs Midwifery
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1995;1:165-7.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/9456733" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 9456733</span></a>]</div></dd><dt>2.</dt><dd><div class="bk_ref" id="LM924.REF.2">Yarnell
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E.
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Botanical medicine in pregnancy and lactation.
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Altern Complement Ther
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1997;3 (April):93-100. doi:10.1089/act.1997.3.93 [<a href="http://dx.crossref.org/10.1089/act.1997.3.93" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></dd><dt>3.</dt><dd><div class="bk_ref" id="LM924.REF.3">Scott
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CR, Jacobson
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H. A selection of international nutritional and herbal remedies for breastfeeding concerns.
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Midwifery Today Int Midwife
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2005;75:38-9.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/16320878" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16320878</span></a>]</div></dd><dt>4.</dt><dd><div class="bk_ref" id="LM924.REF.4">Erarslan
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ZB, Kültür
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S. Medicinal plants traditionally used to increase breast milk in Turkey: An ethnobotanical review.
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J Herbal Med
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2024;44:100849. doi:10.1016/j.hermed.2024.100849 [<a href="http://dx.crossref.org/10.1016/j.hermed.2024.100849" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></dd><dt>5.</dt><dd><div class="bk_ref" id="LM924.REF.5">Brodribb W. ABM Clinical Protocol #9: Use of galactogogues in initiating or augmenting maternal milk production, second revision 2018.
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Breastfeed Med
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2018;13:307-14.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/29902083" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 29902083</span></a>]</div></dd><dt>6.</dt><dd><div class="bk_ref" id="LM924.REF.6">Breastfeeding challenges: ACOG Committee Opinion, Number 820.
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Obstet Gynecol
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2021;137:e42-e53.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/33481531" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 33481531</span></a>]</div></dd><dt>7.</dt><dd><div class="bk_ref" id="LM924.REF.7">Wagner
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CL, Boan
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AD, Marzolf
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A, et al.
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The safety of Mother's Milk(R) Tea: Results of a randomized double-blind, controlled study in fully breastfeeding mothers and their infants.
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J Hum Lact
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2019;35:248–60.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/30005170" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 30005170</span></a>]</div></dd></dl></div></div><div id="LM924.Substance_Identification"><h2 id="_LM924_Substance_Identification_">Substance Identification</h2><div id="LM924.Substance_Name"><h3>Substance Name</h3><p>Marshmallow</p></div><div id="LM924.Scientific_Name"><h3>Scientific Name</h3><p>Althaea officinalis</p></div><div id="LM924.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>73049-65-7</p></div><div id="LM924.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Complementary Therapies</p><p>Phytotherapy</p><p>Plants, Medicinal</p></div></div><div><dl class="temp-labeled-list small"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></div><div id="bk_toc_contnr"></div></div></div>
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