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<script type="text/javascript" src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.boots.min.js"> </script><title>Gallium Citrate Ga 67 - Drugs and Lactation Database (LactMed®) - NCBI Bookshelf</title>
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<meta name="citation_title" content="Gallium Citrate Ga 67">
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<meta name="citation_keywords" content="Neoscan">
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<meta name="citation_keywords" content="Gallium citrate">
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<meta name="citation_keywords" content="Gallium citrate Ga 67">
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<meta name="citation_keywords" content="Gallium-67 citrate">
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<meta name="citation_keywords" content="Gallium citrate ga-67">
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<meta name="citation_keywords" content="Gallium (67 Ga) citrate">
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<meta name="citation_keywords" content="(67-Ga)Gallium citrate">
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<meta name="citation_keywords" content="Gallium citrate (Ga67)">
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<meta name="citation_keywords" content="Gallium (67Ga) citrate">
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<meta name="citation_keywords" content="Gallii (67 Ga) citras">
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<meta name="citation_keywords" content="UNII-4LJK511Z86">
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<meta name="citation_keywords" content="Citrato de galio (67 Ga)">
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<meta name="citation_keywords" content="Citrate de gallium (67 Ga)">
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<meta name="citation_keywords" content="EINECS 255-248-4">
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<meta name="citation_keywords" content="4LJK511Z86">
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<meta name="citation_keywords" content="gallium-67(3+)">
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<meta name="citation_keywords" content="2-hydroxypropane-1,2,3-tricarboxylate">
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<meta name="og:description" content="Information in this record refers to the use of Ga 67 citrate as a diagnostic agent. Several international guidelines recommend discontinuation of breastfeeding for 3 to 4 weeks or complete cessation of breastfeeding after Ga 67 citrate.[1-5] If the mother wishes to resume nursing, the breasts should be emptied regularly and completely during the period of interruption. If the mother has expressed and saved milk prior to the examination, she can feed it to the infant during the period of nursing interruption.[3,6] The milk that is pumped by the mother during the time of breastfeeding interruption can either be discarded or stored frozen and given to the infant after 10 physical half-lives, or about 33 days, have elapsed.[3,6]">
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class="wsprkl btn" title="Jump to next match">▶</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><div class="fm-sec"><h1 id="_NBK501557_"><span class="title" itemprop="name">Gallium Citrate Ga 67</span></h1><p class="fm-aai"><a href="#_NBK501557_pubdet_">Publication Details</a></p><p><em>Estimated reading time: 2 minutes</em></p></div></div><div class="jig-ncbiinpagenav body-content whole_rhythm" data-jigconfig="allHeadingLevels: ['h2'],smoothScroll: false" itemprop="text"><p>CASRN: 41183-64-6</p><a href="https://pubchem.ncbi.nlm.nih.gov/substance/135022196" title="View this structure in PubChem" class="img_link" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubchem"><img src="https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&sid=135022196" alt="image 135022196 in the ncbi pubchem database" /></a><div id="LM665.Drug_Levels_and_Effects"><h2 id="_LM665_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM665.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>Information in this record refers to the use of Ga 67 citrate as a diagnostic agent. Several international guidelines recommend discontinuation of breastfeeding for 3 to 4 weeks or complete cessation of breastfeeding after Ga 67 citrate.[<a class="bibr" href="#LM665.REF.1" rid="LM665.REF.1">1</a>-<a class="bibr" href="#LM665.REF.5" rid="LM665.REF.5">5</a>] If the mother wishes to resume nursing, the breasts should be emptied regularly and completely during the period of interruption. If the mother has expressed and saved milk prior to the examination, she can feed it to the infant during the period of nursing interruption.[<a class="bibr" href="#LM665.REF.3" rid="LM665.REF.3">3</a>,<a class="bibr" href="#LM665.REF.6" rid="LM665.REF.6">6</a>] The milk that is pumped by the mother during the time of breastfeeding interruption can either be discarded or stored frozen and given to the infant after 10 physical half-lives, or about 33 days, have elapsed.[<a class="bibr" href="#LM665.REF.3" rid="LM665.REF.3">3</a>,<a class="bibr" href="#LM665.REF.6" rid="LM665.REF.6">6</a>]</p><p>Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level, she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[<a class="bibr" href="#LM665.REF.7" rid="LM665.REF.7">7</a>] Mothers who receive a dose less than 190 MBq for an inflammation scan need not refrain from close contact with their infants.[<a class="bibr" href="#LM665.REF.8" rid="LM665.REF.8">8</a>]</p></div><div id="LM665.Drug_Levels"><h3>Drug Levels</h3><p>Ga 67 decays by electron capture with principal photon energies of 93, 185 and 300 keV, and a physical half-life of 3.26 days.[<a class="bibr" href="#LM665.REF.4" rid="LM665.REF.4">4</a>] The effective half-life of gallium 67 citrate ranges from 40 to 68 hours.[<a class="bibr" href="#LM665.REF.6" rid="LM665.REF.6">6</a>,<a class="bibr" href="#LM665.REF.7" rid="LM665.REF.7">7</a>]</p></div><div id="LM665.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM665.Effects_on_Lactation_and_Breastmil"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM665.References"><h3>References</h3><dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>1.</dt><dd><div class="bk_ref" id="LM665.REF.1">Mattsson
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S, Johansson
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L, Leide Svegborn
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S, et al.
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Radiation dose to patients from radiopharmaceuticals: A compendium of current information related to frequently used substances. ICRP Publication 128. Annex D. Recommendations on breast-feeding interruptions.
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Ann ICRP
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2015;44:7-321.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/26069086" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26069086</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>2.</dt><dd><div class="bk_ref" id="LM665.REF.2">International Atomic Energy Agency. Radiation Protection and Safety in Medical Uses of Ionizing Radiation, IAEA Safety Standards Series No. SSG-46, IAEA, Vienna. 2018. <a href="https://www.iaea.org/publications/11102/radiation-protection-and-safety-in-medical-uses-of-ionizing-radiation" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.iaea.org<wbr style="display:inline-block"></wbr>​/publications/11102/radiation-protection-and-safety-in-medical-uses-of-ionizing-radiation</a></div></dd></dl><dl class="bkr_refwrap"><dt>3.</dt><dd><div class="bk_ref" id="LM665.REF.3">ARSAC notes for guidance: Good clinical practice in nuclear medicine. Notes for guidance on the clinical administration of radiopharmaceuticals and use of sealed radioactive sources. 2020. <a href="https://www.gov.uk/government/publications/arsac-notes-for-guidance" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.gov.uk/government<wbr style="display:inline-block"></wbr>​/publications<wbr style="display:inline-block"></wbr>​/arsac-notes-for-guidance</a> [<a href="https://pubmed.ncbi.nlm.nih.gov/10732169" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10732169</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>4.</dt><dd><div class="bk_ref" id="LM665.REF.4">Dilsizian V, Metter D, Palestro C, et al. Advisory Committee on Medical Uses of Isotopes (ACMUI) Sub-Committee on Nursing Mother Guidelines for the Medical Administration of Radioactive Material. Final report submitted: January 31, 2019. 2019. <a href="https://www.nrc.gov/docs/ML1903/ML19038A498.pdf" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">https://www<wbr style="display:inline-block"></wbr>​.nrc.gov/docs<wbr style="display:inline-block"></wbr>​/ML1903/ML19038A498.pdf</a></div></dd></dl><dl class="bkr_refwrap"><dt>5.</dt><dd><div class="bk_ref" id="LM665.REF.5">Stabin MG. Doses from medical radiation sources. <a href="https://hps.org/hpspublications/articles/dosesfrommedicalradiation.html" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">https://hps<wbr style="display:inline-block"></wbr>​.org/hpspublications<wbr style="display:inline-block"></wbr>​/articles<wbr style="display:inline-block"></wbr>​/dosesfrommedicalradiation.html</a>. Accessed Nov 6, 2024.</div></dd></dl><dl class="bkr_refwrap"><dt>6.</dt><dd><div class="bk_ref" id="LM665.REF.6">Mountford
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PJ, Coakley
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AJ. A review of the secretion of radioactivity in human breast milk: Data, quantitative analysis and recommendations.
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Nucl Med Commun
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1989;10:15-27.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/2645546" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 2645546</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>7.</dt><dd><div class="bk_ref" id="LM665.REF.7">Stabin
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MG, Breitz
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HB. Breast milk excretion of radiopharmaceuticals: Mechanisms, findings, and radiation dosimetry.
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J Nucl Med
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2000;41:863-73.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/10809203" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10809203</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>8.</dt><dd><div class="bk_ref" id="LM665.REF.8">Mountford
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PJ, O'Doherty
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MJ. Exposure of critical groups to nuclear medicine patients.
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Appl Radiat Isot
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1999;50:89-111.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/10028630" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10028630</span></a>]</div></dd></dl></dl></div></div><div id="LM665.Substance_Identification"><h2 id="_LM665_Substance_Identification_">Substance Identification</h2><div id="LM665.Substance_Name"><h3>Substance Name</h3><p>Gallium Citrate Ga 67</p></div><div id="LM665.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>41183-64-6</p></div><div id="LM665.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Radiopharmaceuticals</p><p>Gallium Radioisotopes</p><p>Diagnostic Agents</p></div></div><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></dl></div><div id="bk_toc_contnr"></div></div></div><div class="fm-sec"><h2 id="_NBK501557_pubdet_">Publication Details</h2><h3>Publication History</h3><p class="small">Last Revision: <span itemprop="dateModified">November 15, 2024</span>.</p><h3>Copyright</h3><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright Notice</a><p class="small"><b>Attribution Statement:</b> LactMed is a registered trademark of the U.S. Department of Health and Human Services.</p></div></div><h3>Publisher</h3><p><a href="https://www.nlm.nih.gov/" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">National Institute of Child Health and Human Development</a>, Bethesda (MD)</p><h3>NLM Citation</h3><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Gallium Citrate Ga 67. [Updated 2024 Nov 15].<span class="bk_cite_avail"></span></p></div><div class="small-screen-prev"><a href="/books/n/lactmed/LM1431/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M75,30 c-80,60 -80,0 0,60 c-30,-60 -30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Prev</text></svg></a></div><div class="small-screen-next"><a href="/books/n/lactmed/LM1244/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M25,30c80,60 80,0 0,60 c30,-60 30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Next</text></svg></a></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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