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<meta name="robots" content="INDEX,FOLLOW,NOARCHIVE" /><meta name="citation_inbook_title" content="Drugs and Lactation Database (LactMed®) [Internet]" /><meta name="citation_title" content="Ropinirole" /><meta name="citation_publisher" content="National Institute of Child Health and Human Development" /><meta name="citation_date" content="2024/02/15" /><meta name="citation_pmid" content="30000578" /><meta name="citation_fulltext_html_url" content="https://www.ncbi.nlm.nih.gov/books/NBK501518/" /><meta name="citation_keywords" content="ropinirole" /><meta name="citation_keywords" content="ropinirol" /><meta name="citation_keywords" content="ReQuip" /><meta name="citation_keywords" content="Ropinirolum" /><meta name="citation_keywords" content="Ropinirolum [INN-Latin]" /><meta name="citation_keywords" content="Ropinirol [INN-Spanish]" /><meta name="citation_keywords" content="SKF 101468" /><meta name="citation_keywords" content="UNII-030PYR8953" /><meta name="citation_keywords" content="SK&F 101468" /><meta name="citation_keywords" content="HSDB 8252" /><meta name="citation_keywords" content="030PYR8953" /><meta name="citation_keywords" content="2H-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-" /><meta name="citation_keywords" content="4-(2-(Dipropylamino)ethyl)-1,3-dihydro-2H-indol-2-one" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Ropinirole" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="National Institute of Child Health and Human Development" /><meta name="DC.Date" content="2024/02/15" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK501518/" /><meta name="description" content="No information is available on the use of ropinirole during breastfeeding, but it suppresses serum prolactin and may interfere with breastfeeding. An alternate drug may be preferred, especially while nursing a newborn or preterm infant." /><meta name="og:title" content="Ropinirole" /><meta name="og:type" content="book" /><meta name="og:description" content="No information is available on the use of ropinirole during breastfeeding, but it suppresses serum prolactin and may interfere with breastfeeding. An alternate drug may be preferred, especially while nursing a newborn or preterm infant." /><meta name="og:url" content="https://www.ncbi.nlm.nih.gov/books/NBK501518/" /><meta name="og:site_name" content="NCBI Bookshelf" /><meta name="og:image" content="https://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-lactmed-lrg.png" /><meta name="twitter:card" content="summary" /><meta name="twitter:site" content="@ncbibooks" /><meta name="bk-non-canon-loc" content="/books/n/lactmed/LM628/" /><link rel="canonical" href="https://www.ncbi.nlm.nih.gov/books/NBK501518/" /><link rel="stylesheet" href="/corehtml/pmc/css/figpopup.css" type="text/css" media="screen" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books.min.css" type="text/css" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books_print.min.css" type="text/css" /><style type="text/css">p a.figpopup{display:inline !important} .bk_tt {font-family: monospace} .first-line-outdent .bk_ref {display: inline} </style><script type="text/javascript" src="/corehtml/pmc/js/jquery.hoverIntent.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/common.min.js?_=3.18"> </script><script type="text/javascript">window.name="mainwindow";</script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/book-toc.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/books.min.js"> </script>
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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. </p></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK501518_"><span class="title" itemprop="name">Ropinirole</span></h1><p class="small">Last Revision: <span itemprop="dateModified">February 15, 2024</span>.</p><p><em>Estimated reading time: 1 minute</em></p></div><div class="body-content whole_rhythm" itemprop="text"><p>CASRN: 91374-21-9</p><a href="https://pubchem.ncbi.nlm.nih.gov/substance/135049181" title="View this structure in PubChem" class="img_link" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubchem"><img src="https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&sid=135049181" alt="image 135049181 in the ncbi pubchem database" /></a><div id="LM628.Drug_Levels_and_Effects"><h2 id="_LM628_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM628.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>No information is available on the use of ropinirole during breastfeeding, but it suppresses serum prolactin and may interfere with breastfeeding. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.</p></div><div id="LM628.Drug_Levels"><h3>Drug Levels</h3><p><i>Maternal Levels.</i> Relevant published information was not found as of the revision date.</p><p><i>Infant Levels.</i> Relevant published information was not found as of the revision date.</p></div><div id="LM628.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM628.Effects_on_Lactation_and_Breastmil"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information on nursing mothers was not found as of the revision date. Ropinirole lowers serum prolactin. It has successfully been used clinically to reduce prolactin levels in women with hyperprolactinemia with relief of galactorrhea.[<a class="bk_pop" href="#LM628.REF.1">1</a>,<a class="bk_pop" href="#LM628.REF.2">2</a>] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.</p></div><div id="LM628.References"><h3>References</h3><dl class="temp-labeled-list"><dt>1.</dt><dd><div class="bk_ref" id="LM628.REF.1">Acton
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G, Broom
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C.
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A dose rising study of the safety and effects on serum prolactin of SK&F 101468, a novel dopamine d2-receptor agonist.
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Br J Clin Pharmacol
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1989;28:435-41.
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[<a href="/pmc/articles/PMC1379994/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1379994</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/2574051" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 2574051</span></a>]</div></dd><dt>2.</dt><dd><div class="bk_ref" id="LM628.REF.2">Heneghan
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LJ, Tsang
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A, Dimino
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C, et al.
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Ropinirole for the treatment of hyperprolactinemia: A dose escalation study of efficacy and tolerability.
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J Clin Endocrinol Metab
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2024;109:e667-e674.
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[<a href="/pmc/articles/PMC10795899/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC10795899</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/37715962" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 37715962</span></a>]</div></dd></dl></div></div><div id="LM628.Substance_Identification"><h2 id="_LM628_Substance_Identification_">Substance Identification</h2><div id="LM628.Substance_Name"><h3>Substance Name</h3><p>Ropinirole</p></div><div id="LM628.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>91374-21-9</p></div><div id="LM628.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Antiparkinson Agents</p><p>Dopamine Agonists</p></div></div><div><dl class="temp-labeled-list small"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></div><div id="bk_toc_contnr"></div></div></div>
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<div class="post-content"><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright Notice</a><p class="small"><b>Attribution Statement:</b> LactMed is a registered trademark of the U.S. Department of Health and Human Services.</p></div><div class="small"><span class="label">Bookshelf ID: NBK501518</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/30000578" title="PubMed record of this page" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">30000578</a></span></div><div style="margin-top:2em" class="bk_noprnt"><a class="bk_cntns" href="/books/n/lactmed/">Contents</a><div class="pagination bk_noprnt"><a class="active page_link prev" href="/books/n/lactmed/romiplostim/" title="Previous page in this title">< Prev</a><a class="active page_link next" href="/books/n/lactmed/LM617/" title="Next page in this title">Next ></a></div></div></div></div>
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