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<meta name="robots" content="INDEX,FOLLOW,NOARCHIVE" /><meta name="citation_inbook_title" content="Drugs and Lactation Database (LactMed®) [Internet]" /><meta name="citation_title" content="Iron Sucrose" /><meta name="citation_publisher" content="National Institute of Child Health and Human Development" /><meta name="citation_date" content="2024/08/15" /><meta name="citation_pmid" content="30000528" /><meta name="citation_fulltext_html_url" content="https://www.ncbi.nlm.nih.gov/books/NBK501468/" /><meta name="citation_keywords" content="Iron sucrose" /><meta name="citation_keywords" content="Iron sugar" /><meta name="citation_keywords" content="Saccharated iron" /><meta name="citation_keywords" content="Succharated ferric oxide" /><meta name="citation_keywords" content="Ferrivenin" /><meta name="citation_keywords" content="Venoferrum" /><meta name="citation_keywords" content="Feojectin" /><meta name="citation_keywords" content="Hippiron" /><meta name="citation_keywords" content="Proferrin" /><meta name="citation_keywords" content="Sucrofer" /><meta name="citation_keywords" content="Velphoro" /><meta name="citation_keywords" content="Encifer" /><meta name="citation_keywords" content="Ferijet" /><meta name="citation_keywords" content="Venofer" /><meta name="citation_keywords" content="Iviron" /><meta name="citation_keywords" content="Fesin" /><meta name="citation_keywords" content="Ferum Hausmann" /><meta name="citation_keywords" content="Neo-ferrum" /><meta name="citation_keywords" content="Ferrum Vitis" /><meta name="citation_keywords" content="Ferosoft S" /><meta name="citation_keywords" content="Ferric saccharate" /><meta name="citation_keywords" content="Fe-back" /><meta name="citation_keywords" content="Ferplex SS" /><meta name="citation_keywords" content="Fe-lib" /><meta name="citation_keywords" content="Colliron I.V." /><meta name="citation_keywords" content="iron saccharate" /><meta name="citation_keywords" content="Saccharated iron oxide" /><meta name="citation_keywords" content="Sucroferric oxyhydroxide" /><meta name="citation_keywords" content="Saccharated ferric oxide" /><meta name="citation_keywords" content="Sucrose, iron complex" /><meta name="citation_keywords" content="Ferrum Hausmann i.v." /><meta name="citation_keywords" content="Iron oxide, saccharated" /><meta name="citation_keywords" content="Succharated ferric oxide" /><meta name="citation_keywords" content="Ferric oxide, saccharated" /><meta name="citation_keywords" content="UNII-FZ7NYF5N8L" /><meta name="citation_keywords" content="FZ7NYF5N8L" /><meta name="citation_keywords" content="ferric hydroxide sucrose complex" /><meta name="citation_keywords" content="EINECS 232-464-7" /><meta name="citation_keywords" content="XI 921" /><meta name="citation_keywords" content="XI-921" /><meta name="citation_keywords" content="Ferric saccharate ...iron oxide (mix.)" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Iron Sucrose" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="National Institute of Child Health and Human Development" /><meta name="DC.Date" content="2024/08/15" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK501468/" /><meta name="description" content="Limited data indicate that breastmilk iron is not increased after intravenous infusion of iron sucrose. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. The oral form of the drug, called sucroferric oxyhydroxide and used as a phosphate binder, is not orally absorbed and it is unlikely to reach the breastmilk or adversely affect the breastfed infant. No special precautions are required. For additional information on iron use during breastfeeding, see the monograph on Iron Salts." /><meta name="og:title" content="Iron Sucrose" /><meta name="og:type" content="book" /><meta name="og:description" content="Limited data indicate that breastmilk iron is not increased after intravenous infusion of iron sucrose. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. The oral form of the drug, called sucroferric oxyhydroxide and used as a phosphate binder, is not orally absorbed and it is unlikely to reach the breastmilk or adversely affect the breastfed infant. No special precautions are required. 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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. </p></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK501468_"><span class="title" itemprop="name">Iron Sucrose</span></h1><p class="small">Last Revision: <span itemprop="dateModified">August 15, 2024</span>.</p><p><em>Estimated reading time: 1 minute</em></p></div><div class="body-content whole_rhythm" itemprop="text"><p>CASRN: 8047-67-4</p><a href="https://pubchem.ncbi.nlm.nih.gov/substance/135280077" title="View this structure in PubChem" class="img_link" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubchem"><img src="https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&sid=135280077" alt="image 135280077 in the ncbi pubchem database" /></a><div id="LM583.Drug_Levels_and_Effects"><h2 id="_LM583_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM583.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>Limited data indicate that breastmilk iron is not increased after intravenous infusion of iron sucrose. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. The oral form of the drug, called sucroferric oxyhydroxide and used as a phosphate binder, is not orally absorbed and it is unlikely to reach the breastmilk or adversely affect the breastfed infant. No special precautions are required. For additional information on iron use during breastfeeding, see the monograph on <a href="/books/n/lactmed/iron_salts/">Iron Salts</a>.</p></div><div id="LM583.Drug_Levels"><h3>Drug Levels</h3><p><i>Maternal Levels.</i> Ten mothers who were iron deficient at 2 to 3 days postpartum received a single 100 mg dose of intravenous iron sucrose. The iron concentration in their colostrum was compared to those in 5 similar women who received no iron. Colostrum collected daily for 4 days after the injection contained average iron concentrations between 0.3 and 0.45 mg/kg of milk which is in the low end of the range for postpartum women. No difference in milk iron concentration was found between the treated and control mothers.[<a class="bk_pop" href="#LM583.REF.1">1</a>]</p><p><i>Infant Levels.</i> Relevant published information was not found as of the revision date.</p></div><div id="LM583.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>In a study of 104 women with postpartum anemia, 78 women received 300 mg of intravenous iron sucrose over 3 days. All women were breastfeeding and had amenorrhea. No adverse reactions were reported in their infants.[<a class="bk_pop" href="#LM583.REF.2">2</a>]</p></div><div id="LM583.Effects_on_Lactation_and_Breastmil"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM583.Alternate_Drugs_to_Consider"><h3>Alternate Drugs to Consider</h3><p><a href="/books/n/lactmed/LM1059/">Ferric Carboxymaltose</a>, <a href="/books/n/lactmed/LM1308/">Ferric Derisomaltose</a></p></div><div id="LM583.References"><h3>References</h3><dl class="temp-labeled-list"><dt>1.</dt><dd><div class="bk_ref" id="LM583.REF.1">Breymann
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C, von Seefried, B, Stahel
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M, et al.
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Milk iron content in breast-feeding mothers after administration of intravenous iron sucrose complex.
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J Perinat Med
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2007;35:115-8.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/17302514" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17302514</span></a>]</div></dd><dt>2.</dt><dd><div class="bk_ref" id="LM583.REF.2">Giannoulis
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C, Daniilidis
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A, Tantanasis
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T, et al.
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Intravenous administration of iron sucrose for treating anemia in postpartum women.
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Hippokratia
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2009;13:38-40.
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[<a href="/pmc/articles/PMC2633251/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2633251</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19240819" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19240819</span></a>]</div></dd></dl></div></div><div id="LM583.Substance_Identification"><h2 id="_LM583_Substance_Identification_">Substance Identification</h2><div id="LM583.Substance_Name"><h3>Substance Name</h3><p>Iron Sucrose</p></div><div id="LM583.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>8047-67-4</p></div><div id="LM583.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Ferric Compounds</p><p>Hematinics</p><p>Iron Compounds</p></div></div><div><dl class="temp-labeled-list small"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></div><div id="bk_toc_contnr"></div></div></div>
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