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<script type="text/javascript" src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.boots.min.js"> </script><title>Benzoyl Peroxide - Drugs and Lactation Database (LactMed&reg;) - NCBI Bookshelf</title>
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<meta name="citation_inbook_title" content="Drugs and Lactation Database (LactMed&reg;) [Internet]">
<meta name="citation_title" content="Benzoyl Peroxide">
<meta name="citation_publisher" content="National Institute of Child Health and Human Development">
<meta name="citation_date" content="2024/11/15">
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<meta name="citation_keywords" content="benzoyl peroxide">
<meta name="citation_keywords" content="Dibenzoyl peroxide">
<meta name="citation_keywords" content="Benzoperoxide">
<meta name="citation_keywords" content="Acetoxyl">
<meta name="citation_keywords" content="Lucidol">
<meta name="citation_keywords" content="Peroxide, dibenzoyl">
<meta name="citation_keywords" content="Benzoyl superoxide">
<meta name="citation_keywords" content="Benoxyl">
<meta name="citation_keywords" content="Panoxyl">
<meta name="citation_keywords" content="Benzol peroxide">
<meta name="citation_keywords" content="Benzoylperoxid">
<meta name="citation_keywords" content="Asidopan">
<meta name="citation_keywords" content="Persadox">
<meta name="citation_keywords" content="Mytolac">
<meta name="citation_keywords" content="Oxylite">
<meta name="citation_keywords" content="Benzac">
<meta name="citation_keywords" content="Eloxyl">
<meta name="citation_keywords" content="Dibenzoylperoxid">
<meta name="citation_keywords" content="Benzoylperoxyde">
<meta name="citation_keywords" content="Theraderm">
<meta name="citation_keywords" content="Resdan Akne">
<meta name="citation_keywords" content="Epi-Clear">
<meta name="citation_keywords" content="Persa-Gel">
<meta name="citation_keywords" content="Akneroxid 5">
<meta name="citation_keywords" content="Dry and Clear">
<meta name="citation_keywords" content="Duresthin 5">
<meta name="citation_keywords" content="Benzaknen">
<meta name="citation_keywords" content="Debroxide">
<meta name="citation_keywords" content="Novadelox">
<meta name="citation_keywords" content="Brevoxyl">
<meta name="citation_keywords" content="Desanden">
<meta name="citation_keywords" content="Dibenzoylperoxyde">
<meta name="citation_keywords" content="Loroxide">
<meta name="citation_keywords" content="Vanoxide">
<meta name="citation_keywords" content="Acnegel">
<meta name="citation_keywords" content="Incidol">
<meta name="citation_keywords" content="Luperco AST">
<meta name="citation_keywords" content="Fostex">
<meta name="citation_keywords" content="Nayper BO">
<meta name="citation_keywords" content="Garox">
<meta name="citation_keywords" content="Topex">
<meta name="citation_keywords" content="Xerac">
<meta name="citation_keywords" content="Luperox fl">
<meta name="citation_keywords" content="Benzashave">
<meta name="citation_keywords" content="Akneroxide L">
<meta name="citation_keywords" content="Benzagel">
<meta name="citation_keywords" content="Cadox bs">
<meta name="citation_keywords" content="Quinolor compound">
<meta name="citation_keywords" content="Desquam E">
<meta name="citation_keywords" content="Clear By Design">
<meta name="citation_keywords" content="Benzac W">
<meta name="citation_keywords" content="Luperco AA">
<meta name="citation_keywords" content="Peroxyde de benzoyle">
<meta name="citation_keywords" content="Diphenylglyoxal peroxide">
<meta name="citation_keywords" content="Benzamycin">
<meta name="citation_keywords" content="Cadox B">
<meta name="citation_keywords" content="Lucidol B 50">
<meta name="citation_keywords" content="Lucidol G 20">
<meta name="citation_keywords" content="Nayper B and bo">
<meta name="citation_keywords" content="Sulfoxyl">
<meta name="citation_keywords" content="Perossido di benzoile">
<meta name="citation_keywords" content="Aztec BPO">
<meta name="citation_keywords" content="Desquam X">
<meta name="citation_keywords" content="Desquam-X">
<meta name="citation_keywords" content="Benbel C">
<meta name="citation_keywords" content="Benzagel 10">
<meta name="citation_keywords" content="Acne-Aid Cream">
<meta name="citation_keywords" content="Lucidol (peroxide)">
<meta name="citation_keywords" content="Benzoic acid, peroxide">
<meta name="citation_keywords" content="Benzefoam">
<meta name="citation_keywords" content="Lavoclen">
<meta name="citation_keywords" content="Benprox">
<meta name="citation_keywords" content="Cadat BPO">
<meta name="citation_keywords" content="Pacnex">
<meta name="citation_keywords" content="Neobenz micro">
<meta name="citation_keywords" content="Lucidol-70">
<meta name="citation_keywords" content="Norox bzp-250">
<meta name="citation_keywords" content="Norox bzp-C-35">
<meta name="citation_keywords" content="Aksil 5">
<meta name="citation_keywords" content="Cadox 40E">
<meta name="citation_keywords" content="Lucidol 50P">
<meta name="citation_keywords" content="Fostex BPO">
<meta name="citation_keywords" content="pHisoAc BP">
<meta name="citation_keywords" content="Xerac BP">
<meta name="citation_keywords" content="Lucidol KL 50">
<meta name="citation_keywords" content="Oxy-10 Cover">
<meta name="citation_keywords" content="Superox 744">
<meta name="citation_keywords" content="Chaloxyd BP 50FT">
<meta name="citation_keywords" content="Abcat 40">
<meta name="citation_keywords" content="Benox 50">
<meta name="citation_keywords" content="Cadox B 40E">
<meta name="citation_keywords" content="Cadox B 50P">
<meta name="citation_keywords" content="Cadox B 70W">
<meta name="citation_keywords" content="Oxy-5">
<meta name="citation_keywords" content="Stri-dex B.P.">
<meta name="citation_keywords" content="Cadox B-CH 50">
<meta name="citation_keywords" content="Benzoylperoxid [German]">
<meta name="citation_keywords" content="Benzoylperoxyde [Dutch]">
<meta name="citation_keywords" content="Benoxyl (5&amp;10) Lotion">
<meta name="citation_keywords" content="Dibenzoylperoxid [German]">
<meta name="citation_keywords" content="Dibenzoylperoxyde [Dutch]">
<meta name="citation_keywords" content="UNII-W9WZN9A0GM">
<meta name="citation_keywords" content="Epi Clear Antiseptic Lotion">
<meta name="citation_keywords" content="BZF-60">
<meta name="citation_keywords" content="OXY-10">
<meta name="citation_keywords" content="W9WZN9A0GM">
<meta name="citation_keywords" content="CCRIS 630">
<meta name="citation_keywords" content="HSDB 372">
<meta name="citation_keywords" content="Perossido di benzoile [Italian]">
<meta name="citation_keywords" content="Clearasil Antibacterial Acne Lotion">
<meta name="citation_keywords" content="NSC 671">
<meta name="citation_keywords" content="B 75W">
<meta name="citation_keywords" content="Clearasil BP Acne Treatment Cream">
<meta name="citation_keywords" content="EINECS 202-327-6">
<meta name="citation_keywords" content="Fostex BPO Bar, Gel, and Wash">
<meta name="citation_keywords" content="G 20">
<meta name="citation_keywords" content="EC 202-327-6">
<meta name="citation_keywords" content="BPO">
<meta name="citation_keywords" content="benzoyl benzenecarboperoxoate">
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<meta name="DC.Title" content="Benzoyl Peroxide">
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<meta name="description" content="Topical benzoyl peroxide has not been studied during breastfeeding. Because only about 5% is absorbed following topical application, it is considered a low risk to the nursing infant.[1,2] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]">
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<meta name="og:description" content="Topical benzoyl peroxide has not been studied during breastfeeding. Because only about 5% is absorbed following topical application, it is considered a low risk to the nursing infant.[1,2] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]">
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id="jr-fip-next" class="wsprkl btn" title="Jump to next match">&#9654;</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><div class="fm-sec"><h1 id="_NBK501421_"><span class="title" itemprop="name">Benzoyl Peroxide</span></h1><p class="fm-aai"><a href="#_NBK501421_pubdet_">Publication Details</a></p><p><em>Estimated reading time: 1 minute</em></p></div></div><div class="jig-ncbiinpagenav body-content whole_rhythm" data-jigconfig="allHeadingLevels: ['h2'],smoothScroll: false" itemprop="text"><p>CASRN: 94-36-0</p><a href="https://pubchem.ncbi.nlm.nih.gov/substance/134971128" title="View this structure in PubChem" class="img_link" ref="pagearea=body&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubchem"><img src="https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&amp;sid=134971128" alt="image 134971128 in the ncbi pubchem database" /></a><div id="LM540.Drug_Levels_and_Effects"><h2 id="_LM540_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM540.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>Topical benzoyl peroxide has not been studied during breastfeeding. Because only about 5% is absorbed following topical application, it is considered a low risk to the nursing infant.[<a class="bibr" href="#LM540.REF.1" rid="LM540.REF.1">1</a>,<a class="bibr" href="#LM540.REF.2" rid="LM540.REF.2">2</a>] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[<a class="bibr" href="#LM540.REF.3" rid="LM540.REF.3">3</a>]</p></div><div id="LM540.Drug_Levels"><h3>Drug Levels</h3><p><i>Maternal Levels.</i> Relevant published information was not found as of the revision date.</p><p><i>Infant Levels.</i> Relevant published information was not found as of the revision date.</p></div><div id="LM540.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM540.Effects_on_Lactation_and_Breastmil"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM540.Alternate_Drugs_to_Consider"><h3>Alternate Drugs to Consider</h3><p>(Acne) <a href="/books/n/lactmed/LM541/?report=reader">Azelaic Acid</a>, <a href="/books/n/lactmed/LM343/?report=reader">Clindamycin</a>, <a href="/books/n/lactmed/LM351/?report=reader">Erythromycin</a>, <a href="/books/n/lactmed/LM539/?report=reader">Tretinoin</a></p></div><div id="LM540.References"><h3>References</h3><dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>1.</dt><dd><div class="bk_ref" id="LM540.REF.1">Leachman
SA, Reed
BR. The use of dermatologic drugs in pregnancy and lactation.
Dermatol Clin
2006;24:167-97.
[<a href="https://pubmed.ncbi.nlm.nih.gov/16677965" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 16677965</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>2.</dt><dd><div class="bk_ref" id="LM540.REF.2">Zip
C.
Common sense dermatological drug suggestions for women who are breast-feeding.
Skin Therapy Lett
2002;7:5-7.
[<a href="https://pubmed.ncbi.nlm.nih.gov/12007012" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 12007012</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>3.</dt><dd><div class="bk_ref" id="LM540.REF.3">Noti
A, Grob
K, Biedermann
M, et al.
Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves.
Regul Toxicol Pharmacol
2003;38:317-25.
[<a href="https://pubmed.ncbi.nlm.nih.gov/14623482" ref="pagearea=cite-ref&amp;targetsite=entrez&amp;targetcat=link&amp;targettype=pubmed">PubMed<span class="bk_prnt">: 14623482</span></a>]</div></dd></dl></dl></div></div><div id="LM540.Substance_Identification"><h2 id="_LM540_Substance_Identification_">Substance Identification</h2><div id="LM540.Substance_Name"><h3>Substance Name</h3><p>Benzoyl Peroxide</p></div><div id="LM540.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>94-36-0</p></div><div id="LM540.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Dermatologic Agents</p><p>Peroxides</p></div></div><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></dl></div><div id="bk_toc_contnr"></div></div></div><div class="fm-sec"><h2 id="_NBK501421_pubdet_">Publication Details</h2><h3>Publication History</h3><p class="small">Last Revision: <span itemprop="dateModified">November 15, 2024</span>.</p><h3>Copyright</h3><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright Notice</a><p class="small"><b>Attribution Statement:</b> LactMed is a registered trademark of the U.S. Department of Health and Human Services.</p></div></div><h3>Publisher</h3><p><a href="https://www.nlm.nih.gov/" ref="pagearea=page-banner&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher">National Institute of Child Health and Human Development</a>, Bethesda (MD)</p><h3>NLM Citation</h3><p>Drugs and Lactation Database (LactMed&#x000ae;) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Benzoyl Peroxide. [Updated 2024 Nov 15].<span class="bk_cite_avail"></span></p></div><div class="small-screen-prev"><a href="/books/n/lactmed/LM845/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M75,30 c-80,60 -80,0 0,60 c-30,-60 -30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Prev</text></svg></a></div><div class="small-screen-next"><a href="/books/n/lactmed/LM29/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M25,30c80,60 80,0 0,60 c30,-60 30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Next</text></svg></a></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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