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name="citation_keywords" content="G 20" /><meta name="citation_keywords" content="EC 202-327-6" /><meta name="citation_keywords" content="BPO" /><meta name="citation_keywords" content="benzoyl benzenecarboperoxoate" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Benzoyl Peroxide" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="National Institute of Child Health and Human Development" /><meta name="DC.Date" content="2024/11/15" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK501421/" /><meta name="description" content="Topical benzoyl peroxide has not been studied during breastfeeding. Because only about 5% is absorbed following topical application, it is considered a low risk to the nursing infant.[1,2] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]" /><meta name="og:title" content="Benzoyl Peroxide" /><meta name="og:type" content="book" /><meta name="og:description" content="Topical benzoyl peroxide has not been studied during breastfeeding. Because only about 5% is absorbed following topical application, it is considered a low risk to the nursing infant.[1,2] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]" /><meta name="og:url" content="https://www.ncbi.nlm.nih.gov/books/NBK501421/" /><meta name="og:site_name" content="NCBI Bookshelf" /><meta name="og:image" content="https://www.ncbi.nlm.nih.gov/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-lactmed-lrg.png" /><meta name="twitter:card" content="summary" /><meta name="twitter:site" content="@ncbibooks" /><meta name="bk-non-canon-loc" content="/books/n/lactmed/LM540/" /><link rel="canonical" href="https://www.ncbi.nlm.nih.gov/books/NBK501421/" /><link rel="stylesheet" href="/corehtml/pmc/css/figpopup.css" type="text/css" media="screen" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books.min.css" type="text/css" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books_print.min.css" type="text/css" /><style type="text/css">p a.figpopup{display:inline !important} .bk_tt {font-family: monospace} .first-line-outdent .bk_ref {display: inline} </style><script type="text/javascript" src="/corehtml/pmc/js/jquery.hoverIntent.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/common.min.js?_=3.18"> </script><script type="text/javascript">window.name="mainwindow";</script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/book-toc.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/books.min.js"> </script>
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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. </p></div></div></div>
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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK501421_"><span class="title" itemprop="name">Benzoyl Peroxide</span></h1><p class="small">Last Revision: <span itemprop="dateModified">November 15, 2024</span>.</p><p><em>Estimated reading time: 1 minute</em></p></div><div class="body-content whole_rhythm" itemprop="text"><p>CASRN: 94-36-0</p><a href="https://pubchem.ncbi.nlm.nih.gov/substance/134971128" title="View this structure in PubChem" class="img_link" ref="pagearea=body&targetsite=entrez&targetcat=link&targettype=pubchem"><img src="https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&sid=134971128" alt="image 134971128 in the ncbi pubchem database" /></a><div id="LM540.Drug_Levels_and_Effects"><h2 id="_LM540_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM540.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>Topical benzoyl peroxide has not been studied during breastfeeding. Because only about 5% is absorbed following topical application, it is considered a low risk to the nursing infant.[<a class="bk_pop" href="#LM540.REF.1">1</a>,<a class="bk_pop" href="#LM540.REF.2">2</a>] Ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[<a class="bk_pop" href="#LM540.REF.3">3</a>]</p></div><div id="LM540.Drug_Levels"><h3>Drug Levels</h3><p><i>Maternal Levels.</i> Relevant published information was not found as of the revision date.</p><p><i>Infant Levels.</i> Relevant published information was not found as of the revision date.</p></div><div id="LM540.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM540.Effects_on_Lactation_and_Breastmil"><h3>Effects on Lactation and Breastmilk</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM540.Alternate_Drugs_to_Consider"><h3>Alternate Drugs to Consider</h3><p>(Acne) <a href="/books/n/lactmed/LM541/">Azelaic Acid</a>, <a href="/books/n/lactmed/LM343/">Clindamycin</a>, <a href="/books/n/lactmed/LM351/">Erythromycin</a>, <a href="/books/n/lactmed/LM539/">Tretinoin</a></p></div><div id="LM540.References"><h3>References</h3><dl class="temp-labeled-list"><dt>1.</dt><dd><div class="bk_ref" id="LM540.REF.1">Leachman
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SA, Reed
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BR. The use of dermatologic drugs in pregnancy and lactation.
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Dermatol Clin
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2006;24:167-97.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/16677965" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16677965</span></a>]</div></dd><dt>2.</dt><dd><div class="bk_ref" id="LM540.REF.2">Zip
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C.
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Common sense dermatological drug suggestions for women who are breast-feeding.
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Skin Therapy Lett
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2002;7:5-7.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/12007012" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 12007012</span></a>]</div></dd><dt>3.</dt><dd><div class="bk_ref" id="LM540.REF.3">Noti
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A, Grob
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K, Biedermann
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M, et al.
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Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves.
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Regul Toxicol Pharmacol
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2003;38:317-25.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/14623482" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 14623482</span></a>]</div></dd></dl></div></div><div id="LM540.Substance_Identification"><h2 id="_LM540_Substance_Identification_">Substance Identification</h2><div id="LM540.Substance_Name"><h3>Substance Name</h3><p>Benzoyl Peroxide</p></div><div id="LM540.CAS_Registry_Number"><h3>CAS Registry Number</h3><p>94-36-0</p></div><div id="LM540.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Dermatologic Agents</p><p>Peroxides</p></div></div><div><dl class="temp-labeled-list small"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></div><div id="bk_toc_contnr"></div></div></div>
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