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<script type="text/javascript" src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.boots.min.js"> </script><title>Phototherapy - Drugs and Lactation Database (LactMed®) - NCBI Bookshelf</title>
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<meta name="citation_inbook_title" content="Drugs and Lactation Database (LactMed®) [Internet]">
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<meta name="citation_title" content="Phototherapy">
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<meta name="citation_publisher" content="National Institute of Child Health and Human Development">
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<meta name="citation_date" content="2024/10/15">
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<meta name="citation_keywords" content="laser acupuncture">
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<meta name="citation_keywords" content="laser phototherapy">
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<meta name="citation_keywords" content="light therapy">
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class="wsprkl btn" title="Jump to next match">▶</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><div class="fm-sec"><h1 id="_NBK500880_"><span class="title" itemprop="name">Phototherapy</span></h1><p class="fm-aai"><a href="#_NBK500880_pubdet_">Publication Details</a></p><p><em>Estimated reading time: 4 minutes</em></p></div></div><div class="jig-ncbiinpagenav body-content whole_rhythm" data-jigconfig="allHeadingLevels: ['h2'],smoothScroll: false" itemprop="text"><div id="LM1293.Drug_Levels_and_Effects"><h2 id="_LM1293_Drug_Levels_and_Effects_">Drug Levels and Effects</h2><div id="LM1293.Summary_of_Use_during_Lactation"><h3>Summary of Use during Lactation</h3><p>In general, laser therapy and phototherapy are considered acceptable during breastfeeding.[<a class="bibr" href="#LM1293.REF.1" rid="LM1293.REF.1">1</a>,<a class="bibr" href="#LM1293.REF.2" rid="LM1293.REF.2">2</a>] Phototherapy for psoriasis is also generally acceptable; however, nursing should be withheld for 24 hours after ingestion of an oral psoralen, such as methoxsalen.[<a class="bibr" href="#LM1293.REF.3" rid="LM1293.REF.3">3</a>]</p><p>Laser therapy was used in some Russian and Austrian studies to prevent and treat lactation mastitis and nipple fissures.[<a class="bibr" href="#LM1293.REF.4" rid="LM1293.REF.4">4</a>-<a class="bibr" href="#LM1293.REF.8" rid="LM1293.REF.8">8</a>] However, these studies are rather old and not well controlled. More recent, well-controlled studies found somewhat conflicting results. In one, laser light applied to the nipple improved the pain from nipple lesions one day sooner than sham therapy.[<a class="bibr" href="#LM1293.REF.9" rid="LM1293.REF.9">9</a>] Another study found greater reductions in nipple pain and fissures with 12 applications of laser phototherapy than a nipple ointment.[<a class="bibr" href="#LM1293.REF.10" rid="LM1293.REF.10">10</a>] In another study, a single application of laser light resulted in no difference in nipple pain during the first 24 hours after application.[<a class="bibr" href="#LM1293.REF.11" rid="LM1293.REF.11">11</a>]</p><p>Some small studies have found that application of laser light to the breasts increases serum prolactin and milk production. Laser application to cesarean section wounds did not adversely affect serum prolactin.[<a class="bibr" href="#LM1293.REF.12" rid="LM1293.REF.12">12</a>]</p><p>A study from China indicated that high-intensity red light (630 nM) plus antibiotics were more effective than antibiotics alone in healing mastitis and preventing recurrence.[<a class="bibr" href="#LM1293.REF.13" rid="LM1293.REF.13">13</a>] Laser light has also been used as part of a 5-step procedure to treat mastitis.[<a class="bibr" href="#LM1293.REF.14" rid="LM1293.REF.14">14</a>]</p></div><div id="LM1293.Effects_in_Breastfed_Infants"><h3>Effects in Breastfed Infants</h3><p>Relevant published information was not found as of the revision date.</p></div><div id="LM1293.Effects_on_Lactation_and_Breastmi"><h3>Effects on Lactation and Breastmilk</h3><p>Use of low-level laser therapy to enhance healing of the surgical incision following cesarean section was evaluated in a small, poorly controlled study. Laser light was applied for 15 minutes on 3 consecutive days postoperatively. On the third day, serum prolactin levels were not significantly different in the two groups. The treatment appeared to help wound healing.[<a class="bibr" href="#LM1293.REF.12" rid="LM1293.REF.12">12</a>]</p><p>A small, randomized study compared primiparous mothers who were supplementing their infants with formula during the first month postpartum and who received either 12 sessions of low-level laser light to the breasts over 3 weeks (n = 20) or no treatment (n = 20). All mothers received similar counseling by a blinded physician certified in lactation counseling. The treated group had greater increases in serum prolactin, and breastmilk lactose, protein and fat at 3 weeks and 3 months after the start of therapy.[<a class="bibr" href="#LM1293.REF.15" rid="LM1293.REF.15">15</a>]</p><p>A randomized study of women (n = 20 in each group) who were mixed feeding their infants in the first month postpartum compared 12 sessions of electroacupuncture or low-level laser therapy to the breast over 1 month and control women. All women also received oral domperidone 10 mg three times daily. Laser therapy increased serum prolactin, infant weight and maternal perception of milk production more than domperidone alone, but less than electroacupuncture.[<a class="bibr" href="#LM1293.REF.16" rid="LM1293.REF.16">16</a>]</p><p>A controlled study in Egypt in breastfeeding women with nipple pain and fissures at 1 to2 weeks after delivery compared photobiomodulation to a topical cream. Photobiomodulation consisted of 12 sessions of low-level laser treatment and the topical cream contained tocopherol, panthenol, almond oil, paraffin oil, petrolatum, and olive oil applied after each feed. The group that received the photobiomodulation had lower values on the visual analogue pain scale and greater infant weight gain at the second, third and fourth week of therapy.[<a class="bibr" href="#LM1293.REF.10" rid="LM1293.REF.10">10</a>]</p></div><div id="LM1293.References"><h3>References</h3><dl class="temp-labeled-list"><dl class="bkr_refwrap"><dt>1.</dt><dd><div class="bk_ref" id="LM1293.REF.1">Lee
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VA. [Use of carbon dioxide laser in the treatment of acute lactation mastitis]. Sov Med
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[<a href="https://pubmed.ncbi.nlm.nih.gov/2513650" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 2513650</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>5.</dt><dd><div class="bk_ref" id="LM1293.REF.5">Kovalev
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MI. [Prevention of lactation mastitis by the use of low-intensity laser irradiation]. Akush Ginekol (Mosk)
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[Use of lasers in the treatment of acute suppurative lactation mastitis]. Vestn Khir Im I I Grek
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[<a href="https://pubmed.ncbi.nlm.nih.gov/3149064" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 3149064</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>8.</dt><dd><div class="bk_ref" id="LM1293.REF.8">Pietschnig
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Efficacy of low level laser therapy in relieving nipple pain in breastfeeding women: A triple-blind, randomized, controlled trial.
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[<a href="https://pubmed.ncbi.nlm.nih.gov/27363734" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 27363734</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>10.</dt><dd><div class="bk_ref" id="LM1293.REF.10">Elseody
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J. Could photobiomodulation help lactating women and their newborns?
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[<a href="/pmc/articles/PMC11269476/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC11269476</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/39046567" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 39046567</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>11.</dt><dd><div class="bk_ref" id="LM1293.REF.11">Camargo
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[<a href="https://pubmed.ncbi.nlm.nih.gov/19405857" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19405857</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>13.</dt><dd><div class="bk_ref" id="LM1293.REF.13">Miao M, Fan CN, Liu N, et al. Clinical application research on the use of carnation photon therapeutic apparatus in treatment for acute postpartum mastitis. Proc 2016 Int Conf Biol Sci Technol 2016:154-7. doi:10.2991/bst-16.2016.24 [<a href="http://dx.crossref.org/10.2991/bst-16.2016.24" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></dd></dl><dl class="bkr_refwrap"><dt>14.</dt><dd><div class="bk_ref" id="LM1293.REF.14">Yao
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[<a href="https://pubmed.ncbi.nlm.nih.gov/34048977" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 34048977</span></a>]</div></dd></dl><dl class="bkr_refwrap"><dt>15.</dt><dd><div class="bk_ref" id="LM1293.REF.15">El Taweel
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2017;12 (Suppl 1):S13. doi:10.1089/bfm.2017.29058.abstracts [<a href="http://dx.crossref.org/10.1089/bfm.2017.29058.abstracts" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></dd></dl><dl class="bkr_refwrap"><dt>16.</dt><dd><div class="bk_ref" id="LM1293.REF.16">Maged
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Effect of low-level laser therapy versus electroacupuncture on postnatal scanty milk secretion: A randomized controlled trial.
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Am J Perinatol
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[<a href="https://pubmed.ncbi.nlm.nih.gov/31327162" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 31327162</span></a>]</div></dd></dl></dl></div></div><div id="LM1293.Substance_Identification"><h2 id="_LM1293_Substance_Identification_">Substance Identification</h2><div id="LM1293.Substance_Name"><h3>Substance Name</h3><p>Phototherapy</p></div><div id="LM1293.Drug_Class"><h3>Drug Class</h3><p>Breast Feeding</p><p>Lactation</p><p>Milk, Human</p><p>Laser Therapy</p><p>Low-Level Light Therapy</p><p>PUVA Therapy</p></div></div><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_top_margin"><p><b>Disclaimer: </b>Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.</p></p></div></dd></dl></dl></div><div id="bk_toc_contnr"></div></div></div><div class="fm-sec"><h2 id="_NBK500880_pubdet_">Publication Details</h2><h3>Publication History</h3><p class="small">Last Revision: <span itemprop="dateModified">October 15, 2024</span>.</p><h3>Copyright</h3><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright Notice</a><p class="small"><b>Attribution Statement:</b> LactMed is a registered trademark of the U.S. Department of Health and Human Services.</p></div></div><h3>Publisher</h3><p><a href="https://www.nlm.nih.gov/" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">National Institute of Child Health and Human Development</a>, Bethesda (MD)</p><h3>NLM Citation</h3><p>Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Phototherapy. [Updated 2024 Oct 15].<span class="bk_cite_avail"></span></p></div><div class="small-screen-prev"><a href="/books/n/lactmed/LM1148/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M75,30 c-80,60 -80,0 0,60 c-30,-60 -30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Prev</text></svg></a></div><div class="small-screen-next"><a href="/books/n/lactmed/LM835/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M25,30c80,60 80,0 0,60 c30,-60 30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Next</text></svg></a></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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