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<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/CreativeWork"><div class="meta-content fm-sec"><h1 id="_NBK26469_"><span class="title" itemprop="name">NCBI News, February 2010</span></h1><p class="contrib-group"><span itemprop="author">Peter Cooper</span>, PhD and <span itemprop="author">Dawn Lipshultz</span>, MS.</p><a data-jig="ncbitoggler" href="#__NBK26469_ai__" style="border:0;text-decoration:none">Author Information and Affiliations</a><div style="display:none" class="ui-widget" id="__NBK26469_ai__"><div class="contrib half_rhythm"><span itemprop="author">Peter Cooper</span>, PhD<div class="affiliation small">NCBI<div><span class="email-label">Email: </span><a href="mailto:dev@null" data-email="vog.hn.mln.ibcn@repooc" class="oemail">vog.hn.mln.ibcn@repooc</a></div></div></div><div class="contrib half_rhythm"><span itemprop="author">Dawn Lipshultz</span>, MS<div class="affiliation small">NCBI<div><span class="email-label">Email: </span><a href="mailto:dev@null" data-email="vog.hin.mln.ibcn@tluhspil" class="oemail">vog.hin.mln.ibcn@tluhspil</a></div></div></div></div><p class="small">Created: <span itemprop="datePublished">March 4, 2010</span>; Last Update: <span itemprop="dateModified">March 11, 2010</span>.</p><p><em>Estimated reading time: 2 minutes</em></p></div><div class="jig-ncbiinpagenav body-content whole_rhythm" data-jigconfig="allHeadingLevels: ['h2'],smoothScroll: false" itemprop="text"><div id="KCKQBm746.NewDatab1_1"><h2 id="_KCKQBm746_NewDatab1_1_">New Databases and Tools</h2><div id="KCKQBm746.dbVar2_2"><h3>dbVar</h3><p>The newly released Database of Genomic Structural Variation (dbVar) contains data and analyses from studies on large-scale genomic variation and provides associations of defined variants with phenotype information. The <a href="/dbvar/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">dbVar homepage</a> provides additional documentation including an overview of structural variation, a Frequently Asked Questions list, and information on submitting data. A dbVar <a href="/feed/rss.cgi?ChanKey=dbvarnews" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">RSS feed</a> has also been established to provide announcements and updates.</p></div><div id="KCKQBm746.NLMPress3_2"><h3>NLM Press Release </h3><p>NCBI scientists have assisted in the design of a computational model to accurately detect signals of regulatory elements responsible for development of the human heart and it’s maintenance of function. An <a href="http://www.nih.gov/news/health/feb2010/nlm-17.htm" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">NIH Press Release</a> provides more information on this project. </p></div><div id="KCKQBm746.Bookshel4_2"><h3>Bookshelf</h3><p>New books added to the Bookshelf include: <i>Patient Safety and Quality: An Evidence-Based Handbook for Nurses, Familial Cancer Syndromes, </i>and <i>UMLS Reference Manual</i>. To view these and other books see: <a href="/sites/entrez?db=Books" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">www.ncbi.nlm.nih.gov/sites/entrez?db=Books</a>.</p></div><div id="KCKQBm746.E-Utilit5_2"><h3>E-Utilities Documentation</h3><p>The <a href="/bookshelf/br.fcgi?book=helpeutils" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">Entrez Programming Utilities</a> (E-Utilities) Help documentation has been added to the NCBI Bookshelf. This help document has been split into chapters for better organization and is now fully integrated with the Entrez search and retrieval system as a part of the Bookshelf database.</p></div><div id="KCKQBm746.Microbia6_2"><h3>Microbial Genomes</h3><p>Twenty-two finished microbial genomes were added to the NCBI databases during February. The original sequence data files submitted to GenBank/EMBL/DDBJ are on the FTP site: <a href="ftp://ftp.ncbi.nih.gov/genbank/genomes/Bacteria/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=ftp">ftp.ncbi.nih.gov/genbank/genomes/Bacteria/</a>. The RefSeq provisional versions of these genomes are also available: <a href="ftp://ftp.ncbi.nih.gov/genomes/Bacteria/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=ftp">ftp.ncbi.nih.gov/genomes/Bacteria/</a>.</p></div></div><div id="KCKQBm746.GenBankN7_1"><h2 id="_KCKQBm746_GenBankN7_1_">GenBank News</h2><p>GenBank release 176.0 is available on the NCBI Web Service and FTP site. The current release incorporates sequence data as of February 19, 2010. Release notes containing detailed information are available on the FTP site: <a href="ftp://ftp.ncbi.nlm.nih.gov/genbank/gbrel.txt" ref="pagearea=body&targetsite=external&targetcat=link&targettype=ftp">ftp.ncbi.nlm.nih.gov/genbank/gbrel.txt</a>. </p></div><div id="KCKQBm746.Updatesa8_1"><h2 id="_KCKQBm746_Updatesa8_1_">Updates and Enhancements</h2><div id="KCKQBm746.BLAST9_2"><h3>BLAST</h3><p>The NCBI BLAST development team reports on improvements in the updated C++ BLAST software in the December issue of <i>BMC Bioinformatics</i>:</p><p>Camacho C, Coulouris G, Avagyan V, Ma N, Papadopoulos J, Bealer K, Madden TL. BLAST+: architecture and applications. <i>BMC Bioinformatics</i>. 2009. Dec 15;10:421. PMID: <a href="/pubmed/20003500" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">20003500</a>; PMCID: <a href="/pmc/articles/PMC2803857/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">PMC2803857</a>.</p><p>The article illustrates the new BLAST+ suites’ improved user interface, enhanced performance for long sequences, and better integration with the NCBI Web BLAST service.</p></div><div id="KCKQBm746.Exhibits10_2"><h3>Exhibits</h3><p>NCBI will have an exhibit booth at the American Association for Cancer Research annual meeting held April 17-21 in Washington, D.C.</p></div></div><div id="KCKQBm746.Announce11_1"><h2 id="_KCKQBm746_Announce11_1_">Announce Lists and RSS Feeds</h2><p>Eighteen topic-specific mailing lists are available which provide email announcements about changes and updates to NCBI resources including dbGaP, BLAST, GenBank, and Sequin. The various lists are described on the Announcement List summary page: <a href="/Sitemap/Summary/email_lists.html" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">www.ncbi.nlm.nih.gov/Sitemap/Summary/email_lists.html</a>. To receive updates on the <i>NCBI News</i>, please see: <a href="/About/news/announce_submit.html" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">www.ncbi.nlm.nih.gov/About/news/announce_submit.html</a></p><p>Twelve RSS feeds are now available from NCBI including news on PubMed, PubMed Central, NCBI Bookshelf, LinkOut, HomoloGene, UniGene, and NCBI Announce. Please see: <a href="/feed/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">www.ncbi.nlm.nih.gov/feed/</a></p><p>Send comments and questions about NCBI resources to: <a href="mailto:dev@null" data-email="vog.hin.mln.ibcn@ofni" class="oemail">vog.hin.mln.ibcn@ofni</a>, or by calling 301-496-2475 between the hours of 8:30 a.m. and 5:30 p.m. EST, Monday through Friday.</p></div><div id="bk_toc_contnr"></div></div></div>
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