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<title>Box 5.33, Generalized structure of bone and the process of osteocytic osteolysis - Endocrinology - NCBI Bookshelf</title>
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<meta name="robots" content="NOINDEX,NOFOLLOW,NOARCHIVE,NOIMAGEINDEX" /><link rel="schema.DC" href="http://purl.org/DC/elements/1.0/" /><meta name="DC.Title" content="Box 5.33, Generalized structure of bone and the process of osteocytic osteolysis" /><meta name="DC.Type" content="Text" /><meta name="DC.Publisher" content="BIOS Scientific Publishers" /><meta name="DC.Contributor" content="Stephen Nussey" /><meta name="DC.Contributor" content="Saffron Whitehead" /><meta name="DC.Date" content="2001" /><meta name="DC.Identifier" content="https://www.ncbi.nlm.nih.gov/books/NBK24/" /><meta name="description" content="A schematic diagram of cortical and trabecular bone is shown in the upper figure together with the osteons where bone remodeling occurs. Surface osteoblasts become osteocytes as they become surrounded by mineralized bone but they remain in contact with the bone surface through long synctial (cytoplasmic) processes which run in the fluid filled lacunae. They are connected to the surface osteoblasts through gap junctions. Ca2+ in the lacunae is in equilibrium with plasma Ca2+ but, under the action of parathyroid hormone (PTH), Ca2+ is taken up by the osteocytes, transported to the surface osteoblasts which pump the Ca2+ into the extracellular fluid, thus raising plasma Ca2+ concentrations." /><meta name="bk-non-canon-loc" content="/books/n/endocrin/A742/" /><link rel="canonical" href="https://www.ncbi.nlm.nih.gov/books/NBK24/" /><link rel="stylesheet" href="/corehtml/pmc/css/figpopup.css" type="text/css" media="screen" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books.min.css" type="text/css" /><link rel="stylesheet" href="/corehtml/pmc/css/bookshelf/2.26/css/books_print.min.css" type="text/css" media="print" /><style type="text/css">p a.figpopup{display:inline !important} .bk_tt {font-family: monospace} .first-line-outdent .bk_ref {display: inline} </style><script type="text/javascript" src="/corehtml/pmc/js/jquery.hoverIntent.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/common.min.js?_=3.18"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/book-toc.min.js"> </script><script type="text/javascript" src="/corehtml/pmc/js/bookshelf/2.26/books.min.js"> </script>
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<div class="main-content lit-style"><div class="body-content whole_rhythm"><div id="A822" class="box"><h3><span class="label">Box 5.33</span><span class="title">Generalized structure of bone and the process of osteocytic osteolysis</span></h3><div class="graphic"><img src="/books/NBK24/bin/ch5fb33.jpg" alt="Image ch5fb33.jpg" /></div><p>A schematic diagram of cortical and trabecular bone is shown in the upper figure together with the osteons where bone remodeling occurs. Surface osteoblasts become osteocytes as they become surrounded by mineralized bone but they remain in contact with the bone surface through long synctial (cytoplasmic) processes which run in the fluid filled lacunae. They are connected to the surface osteoblasts through gap junctions. Ca<sup>2+</sup> in the lacunae is in equilibrium with plasma Ca<sup>2+</sup> but, under the action of parathyroid hormone (PTH), Ca<sup>2+</sup> is taken up by the osteocytes, transported to the surface osteoblasts which pump the Ca<sup>2+</sup> into the extracellular fluid, thus raising plasma Ca<sup>2+</sup> concentrations.</p></div><div id="bk_toc_contnr"></div></div></div>
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<div class="post-content"><div><p>From: <a href="/books/NBK24/" target="mainwindow">Chapter 5, The parathyroid glands and vitamin D</a></p><div class="iconblock clearfix ten_col"><a class="img_link icnblk_img" title="Table of Contents Page" href="/books/n/endocrin/" target="mainwindow"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-endocrin-lrg.png" alt="Cover of Endocrinology" height="100px" width="80px" /></a><div class="icnblk_cntnt"><div><div>Endocrinology: An Integrated Approach.</div><div>Nussey S, Whitehead S.</div><div>Oxford: <a href="http://www.garlandscience.com/about.asp" target="mainwindow" ref="pagearea=content-footer&targetsite=external&targetcat=link&targettype=publisher">BIOS Scientific Publishers</a>; 2001.</div></div></div></div><div class="half_rhythm"><a href="/books/about/copyright/" target="mainwindow">Copyright</a> © 2001, BIOS Scientific Publishers Limited.</div><p>NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p></div></div>
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