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<script type="text/javascript" src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.boots.min.js"> </script><title>Vaccines for the 21st Century - NCBI Bookshelf</title>
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<meta name="author" content="Institute of Medicine (US) Committee to Study Priorities for Vaccine Development; Kathleen R. Stratton, Jane S. Durch, Robert S. Lawrence">
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<meta name="citation_author" content="Kathleen R. Stratton">
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<meta name="citation_author" content="Jane S. Durch">
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<meta name="citation_author" content="Robert S. Lawrence">
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preserveAspectRatio="none"><path fill="none" stroke="#000" stroke-width="36" stroke-linecap="round" style="fill:#FFF" d="m320,350a153,153 0 1,0-2,2l170,170m-91-117 110,110-26,26-110-110"></path></svg></a><a id="jr-fip-done" class="wsprkl btn" title="Dismiss find">✘</a></nav><nav id="jr-fip-info-p"><a id="jr-fip-prev" class="wsprkl btn" title="Jump to previuos match">◀</a><button id="jr-fip-matches">no matches yet</button><a id="jr-fip-next" class="wsprkl btn" title="Jump to next match">▶</a></nav></nav></div><div id="jr-epub-interstitial" class="hidden"></div><div id="jr-content"><article data-type="main"><div class="main-content lit-style"><div class="fm-sec bkr_bottom_sep"><div class="bkr_thumb"><a href="http://www.nap.edu/catalog.php?record_id=5501" title="National Academies Press (US)" class="img_link icnblk_img" ref="pagearea=logo&targetsite=external&targetcat=link&targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nap5501-lrg.png" alt="Cover of Vaccines for the 21st Century" /></a></div><div class="bkr_bib"><h1 id="_NBK233313_"><span itemprop="name">Vaccines for the 21st Century</span></h1><div class="subtitle">A Tool for Decisionmaking</div><p class="contrib-group"><h4>Contributors</h4><span itemprop="author">Institute of Medicine (US) Committee to Study Priorities for Vaccine Development</span>; Editors: <span itemprop="editor">Kathleen R. Stratton</span>, <span itemprop="editor">Jane S. Durch</span>, and <span itemprop="editor">Robert S. Lawrence</span>.</p><div class="half_rhythm">Washington (DC): <a href="http://www.nap.edu/" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">National Academies Press (US)</span></a>; <span itemprop="datePublished">2000</span>.<div class="small">ISBN-10: <span itemprop="isbn">0-309-05646-2</span></div></div><div><a href="/books/about/copyright/">Copyright</a> 2000 by the National Academy of Sciences. All rights reserved.</div><div class="small half_rhythm bk_noprnt"><a href="http://www.nap.edu/catalog.php?record_id=5501" ref="pagearea=body&targetsite=external&targetcat=link&targettype=publisher">Hardcopy Version at National Academies Press</a></div><a class="btn wsprkl bkr_rd" href="/books/n/nap5501/ddd00004/?report=reader">Read</a></div><div class="bkr_clear"></div></div><div class="bkr_bottom_sep bkr_bottom_margin body-content whole_rhythm"><div itemprop="description"><p>Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis.</p><p>What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development.</p><p>This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines:</p><ul><li class="half_rhythm"><div>Lessons to be learned from the polio experience.</div></li><li class="half_rhythm"><div>Scientific advances that set the stage for new vaccines.</div></li><li class="half_rhythm"><div>Factors that affect how vaccines are used in the population.</div></li><li class="half_rhythm"><div>Value judgments and ethical questions raised by comparison of health needs and benefits.</div></li></ul><p>The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.</p></div></div></div><div class="fm-sec"><div><p>This project has been funded in whole with federal funds from the National Institutes of Allergy and Infectious Diseases, National Institutes of Health, under Contract No. N01-AI-45237. The views presented are those of the Institute of Medicine Committee to Study Priorities for Vaccine Development and are not necessarily those of the funding organization.</p></div><div><p>NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.</p></div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> 2000 by the National Academy of Sciences. All rights reserved.</div><div class="small"><span class="label">Bookshelf ID: NBK233313</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/25121214" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">25121214</a></span>DOI: <a href="http://dx.crossref.org/10.17226/5501" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">10.17226/5501</a></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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