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<div class="pre-content"><div><div class="bk_prnt"><p class="small">NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p></div><div class="pagination bk_noprnt"><span class="inactive page_link prev">&lt; Prev</span><a class="active page_link next" href="/books/n/ce2/A15/" title="Next page in this title">Next &gt;</a></div></div></div>
<div class="main-content lit-style" itemscope="itemscope" itemtype="http://schema.org/Book"><div class="meta-content fm-sec"><div class="iconblock whole_rhythm clearfix no_top_margin"><a href="http://www.cshlpress.com/default.tpl?cart=1316629246104349394&amp;fromlink=T&amp;linkaction=full&amp;linksortby=oop_title&amp;--eqSKUdatarq=38" title="Cold Spring Harbor Laboratory Press" class="img_link icnblk_img" ref="pagearea=logo&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-ce2-lrg.png" alt="Cover of C. elegans II" /></a><div class="icnblk_cntnt"><h1 id="_NBK19997_"><span itemprop="name"><i>C. elegans</i> II</span>, <span itemprop="bookEdition">2nd</span> edition</h1><p><i>Cold Spring Harbor Mongraph Series, Vol. 33</i></p><p class="contrib-group">Editors: <span itemprop="editor">Donald L Riddle</span>, <span itemprop="editor">Thomas Blumenthal</span>, <span itemprop="editor">Barbara J Meyer</span>, and <span itemprop="editor">James R Priess</span>.</p><a data-jig="ncbitoggler" href="#__NBK19997_ai__" style="border:0;text-decoration:none">Editor Information</a><div style="display:none" class="ui-widget" id="__NBK19997_ai__"><p class="contrib-group"><h4>Editors</h4>Editors: <span itemprop="editor">Donald L Riddle</span>,<sup>1</sup> <span itemprop="editor">Thomas Blumenthal</span>,<sup>2</sup> <span itemprop="editor">Barbara J Meyer</span>,<sup>3</sup> and <span itemprop="editor">James R Priess</span><sup>4</sup>.</p><h4>Affiliations</h4><div class="affiliation"><sup>1</sup> University of Missouri, Columbia</div><div class="affiliation"><sup>2</sup> Indiana University</div><div class="affiliation"><sup>3</sup> University of California, Berkeley</div><div class="affiliation"><sup>4</sup> Howard Hughes Medical Institute, Fred Hutchinson Cancer Research
Center, Seattle, Washington</div></div><div class="half_rhythm">Cold Spring Harbor (NY): <a href="http://www.cshlpress.com/" ref="pagearea=meta&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher"><span itemprop="publisher">Cold Spring Harbor Laboratory Press</span></a>; <span itemprop="datePublished">1997</span>.<div class="small">ISBN-10: <span itemprop="isbn">0-87969-532-3</span></div></div><div class="half_rhythm"><ul class="inline_list"><li><span class="label"><a data-jig="ncbidialog" href="#_ncbi_dlg_cpyrght_NBK19997" data-jigconfig="modal:true">Copyright and
Permissions</a></span></li></ul></div><div id="_ncbi_dlg_cpyrght_NBK19997" style="display:none" title="Copyright and&#10; Permissions"><div><div>Copyright &#x000a9; 1997, Cold Spring Harbor Laboratory Press.</div><div>For more information, see the <a href="/books/about/copyright/">Bookshelf Copyright Notice</a>.</div></div></div><div class="small half_rhythm bk_noprnt"><a href="http://www.cshlpress.com/default.tpl?cart=1316629246104349394&amp;fromlink=T&amp;linkaction=full&amp;linksortby=oop_title&amp;--eqSKUdatarq=38" ref="pagearea=body&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher">Hardcopy Version at Cold Spring Harbor Laboratory Press</a></div><div class="bk_noprnt"><form method="get" action="/books/n/ce2/" id="bk_srch"><div class="bk_search"><label for="bk_term" class="offscreen_noflow">Search term</label><input type="text" title="Search this book" id="bk_term" name="term" value="" data-jig="ncbiclearbutton" /> <input type="submit" class="jig-ncbibutton" value="Search this book" submit="false" style="padding: 0.1em 0.4em;" /></div></form></div></div></div></div><div class="body-content whole_rhythm" itemprop="text"><div itemprop="description"><h2>Excerpt</h2><p>Why should one study a worm? This simple creature is one of several
&#x0201c;model&#x0201d; organisms that together have provided tremendous insight
into how all organisms are put together. It has become increasingly clear over the
past two decades that knowledge from one organism, even one so simple as a worm, can
provide tremendous power when connected with knowledge from other organisms. And
because of the experimental accessibility of nematodes, knowledge about worms can
come more quickly and cheaply than knowledge about higher organisms.</p></div><div><h2>Contents</h2><div class="bktoc_all_cntnr top align_right" style="display:none"><ul class="inline_list_right"><li><a class="bktoc_all_exp" href="#">Expand All</a></li><li style="margin-left:.8em"><a class="bktoc_all_clps" href="#">Collapse All</a></li></ul></div><ul id="toc_tllNBK19997_A15" class="simple-list toc toc-toggle"><li class="half_rhythm" id="toc_itm_NBK19997_A15"><a href="/books/n/ce2/A15/" class="toc-item">Reviewers</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A17"><a href="/books/n/ce2/A17/" class="toc-item">Preface</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A18"><a href="/books/n/ce2/A18/" class="toc-item">Foreword</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A19"><a href="/books/n/ce2/A19/" class="toc-item">Chapter 1. Introduction to <i>C. elegans</i></a><div>Donald L Riddle, Thomas Blumenthal, Barbara J Meyer, and James R Priess.</div><ul id="toc_lst_NBK19997_A24" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A24"><a href="/books/n/ce2/A24/" class="toc-item">I The Biological Model</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A26"><a href="/books/n/ce2/A26/" class="toc-item">II Origins of the Model</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A27"><a href="/books/n/ce2/A27/" class="toc-item">III Life History And Evolution</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A28"><a href="/books/n/ce2/A28/" class="toc-item">IV Anatomy</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A31"><a href="/books/n/ce2/A31/" class="toc-item">V Resources</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A34"><a href="/books/n/ce2/A34/" class="toc-item">VI Current Issues</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A38"><a href="/books/n/ce2/A38/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A39"><a href="/books/n/ce2/A39/" class="toc-item">Chapter 2. The Genome</a><div>Robert H Waterston, John E Sulston, and Alan R Coulson.</div><ul id="toc_lst_NBK19997_A42" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A42"><a href="/books/n/ce2/A42/" class="toc-item">I General Properties</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A43"><a href="/books/n/ce2/A43/" class="toc-item">II The Physical Map</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A47"><a href="/books/n/ce2/A47/" class="toc-item">III Genetics, Genes, and the Physical Map</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A50"><a href="/books/n/ce2/A50/" class="toc-item">IV Genome Sequencing</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A51"><a href="/books/n/ce2/A51/" class="toc-item">V EST Sequencing</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A52"><a href="/books/n/ce2/A52/" class="toc-item">VI Interpretation of the Sequence</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A54"><a href="/books/n/ce2/A54/" class="toc-item">VII Tentative Conclusions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A60"><a href="/books/n/ce2/A60/" class="toc-item">VIII Prospects</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A61"><a href="/books/n/ce2/A61/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A62"><a href="/books/n/ce2/A62/" class="toc-item">Chapter 3. Chromosome Organization, Mitosis, and Meiosis</a><div>Donna G Albertson, Ann M Rose, and Anne M Villeneuve.</div><ul id="toc_lst_NBK19997_A66" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A66"><a href="/books/n/ce2/A66/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A67"><a href="/books/n/ce2/A67/" class="toc-item">II Mitosis</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A77"><a href="/books/n/ce2/A77/" class="toc-item">III Meiosis</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A94"><a href="/books/n/ce2/A94/" class="toc-item">IV Prospects</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A95"><a href="/books/n/ce2/A95/" class="toc-item">Chapter 4. Mutation</a><div>Robert C Johnsen and David L Baillie.</div><ul id="toc_lst_NBK19997_A98" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A98"><a href="/books/n/ce2/A98/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A100"><a href="/books/n/ce2/A100/" class="toc-item">II Induced Mutations</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A105"><a href="/books/n/ce2/A105/" class="toc-item">III Genetic Balancers</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A108"><a href="/books/n/ce2/A108/" class="toc-item">IV Genetically Detectable Genes</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A109"><a href="/books/n/ce2/A109/" class="toc-item">V What are Essential Genes?</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A110"><a href="/books/n/ce2/A110/" class="toc-item">VI Gene Distribution</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A111"><a href="/books/n/ce2/A111/" class="toc-item">VII Summary</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A112"><a href="/books/n/ce2/A112/" class="toc-item">Acknowledgment</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A113"><a href="/books/n/ce2/A113/" class="toc-item">Chapter 5. Transposons</a><div>Ronald H A Plasterk and Henri G A M van Luenen.</div><ul id="toc_lst_NBK19997_A115" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A115"><a href="/books/n/ce2/A115/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A116"><a href="/books/n/ce2/A116/" class="toc-item">II Tc1 and Tc3</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A118"><a href="/books/n/ce2/A118/" class="toc-item">III Other Elements</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A119"><a href="/books/n/ce2/A119/" class="toc-item">IV The Tc1/<i>mariner</i> Family</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A121"><a href="/books/n/ce2/A121/" class="toc-item">V Regulation of Tc1/<i>mariner</i> Transposition</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A124"><a href="/books/n/ce2/A124/" class="toc-item">VI Mechanism of Tc1 Transposition</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A133"><a href="/books/n/ce2/A133/" class="toc-item">VII Repair After Tc1 Excision</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A134"><a href="/books/n/ce2/A134/" class="toc-item">VIII Tc1 as a Tool in
<i>C. elegans</i>
Research</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A142"><a href="/books/n/ce2/A142/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A143"><a href="/books/n/ce2/A143/" class="toc-item">Chapter 6. RNA Processing and Gene Structure</a><div>Thomas Blumenthal and Keith Steward.</div><ul id="toc_lst_NBK19997_A145" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A145"><a href="/books/n/ce2/A145/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A148"><a href="/books/n/ce2/A148/" class="toc-item">II
<i>Cis</i>
-Splicing in Worms</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A158"><a href="/books/n/ce2/A158/" class="toc-item">III
<i>Trans</i>
-Splicing</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A165"><a href="/books/n/ce2/A165/" class="toc-item">IV SL2
<i>Trans</i>
-Splicing and Operons</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A174"><a href="/books/n/ce2/A174/" class="toc-item">V
<i>Trans</i>
-Splicing in Vitro</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A175"><a href="/books/n/ce2/A175/" class="toc-item">VI Frequency of Operons and
<i>Trans</i>
-Splicing</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A176"><a href="/books/n/ce2/A176/" class="toc-item">VII Organization and Transcription of Spliced Leader RNA Genes</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A177"><a href="/books/n/ce2/A177/" class="toc-item">VIII 3&#x02032;-End Formation</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A181"><a href="/books/n/ce2/A181/" class="toc-item">IX Translation Initiation and Termination Signals</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A182"><a href="/books/n/ce2/A182/" class="toc-item">X Conclusions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A183"><a href="/books/n/ce2/A183/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A184"><a href="/books/n/ce2/A184/" class="toc-item">Chapter 7. Transcription Factors and Transcriptional Regulation</a><div>James D McGhee and Michael W. Krause.</div><ul id="toc_lst_NBK19997_A187" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A187"><a href="/books/n/ce2/A187/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A188"><a href="/books/n/ce2/A188/" class="toc-item">II The Basal Transcription Machinery</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A189"><a href="/books/n/ce2/A189/" class="toc-item">III Transcription Factors</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A254"><a href="/books/n/ce2/A254/" class="toc-item">IV Analysis of
<i>C. elegans</i>
Promoters</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A265"><a href="/books/n/ce2/A265/" class="toc-item">V Future Prospects</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A266"><a href="/books/n/ce2/A266/" class="toc-item">Chapter 8. mRNA and Translation</a><div>Philip Anderson and Judith Kimble.</div><ul id="toc_lst_NBK19997_A269" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A269"><a href="/books/n/ce2/A269/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A270"><a href="/books/n/ce2/A270/" class="toc-item">II The Translational Apparatus</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A273"><a href="/books/n/ce2/A273/" class="toc-item">III Informational Suppressors</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A295"><a href="/books/n/ce2/A295/" class="toc-item">IV Regulation of Translation During Development</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A308"><a href="/books/n/ce2/A308/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A309"><a href="/books/n/ce2/A309/" class="toc-item">Chapter 9. Sex Determination and X Chromosome Dosage Compensation</a><div>Barbara J Meyer.</div><ul id="toc_lst_NBK19997_A311" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A311"><a href="/books/n/ce2/A311/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A312"><a href="/books/n/ce2/A312/" class="toc-item">II Sexual Dimorphism</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A314"><a href="/books/n/ce2/A314/" class="toc-item">III The Primary Sex-Determination Signal and its Gene Target</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A318"><a href="/books/n/ce2/A318/" class="toc-item">IV Hermaphrodite-Specific Genes that Coordinately Control Sex Determination and
Dosage Compensation</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A320"><a href="/books/n/ce2/A320/" class="toc-item">V X Chromosome Dosage Compensation</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A327"><a href="/books/n/ce2/A327/" class="toc-item">VI Somatic Sex Determination</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A332"><a href="/books/n/ce2/A332/" class="toc-item">VII Sex Determination in The Germ Line Versus the Soma</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A333"><a href="/books/n/ce2/A333/" class="toc-item">VIII Concluding Remarks</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A334"><a href="/books/n/ce2/A334/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A335"><a href="/books/n/ce2/A335/" class="toc-item">Chapter 10. Developmental Genetics of the Germ Line</a><div>Tim Schedl.</div><ul id="toc_lst_NBK19997_A337" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A337"><a href="/books/n/ce2/A337/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A338"><a href="/books/n/ce2/A338/" class="toc-item">II Summary of Anatomy and Development of the Germ Line</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A342"><a href="/books/n/ce2/A342/" class="toc-item">III Genetic Analysis of Germ-Line Development</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A345"><a href="/books/n/ce2/A345/" class="toc-item">IV Somatic Gonad</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A346"><a href="/books/n/ce2/A346/" class="toc-item">V Germ-Line Specification and Survival</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A347"><a href="/books/n/ce2/A347/" class="toc-item">VI Germ-Line Sex Determination</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A354"><a href="/books/n/ce2/A354/" class="toc-item">VII Control of Proliferation and Entry into the Meiotic Pathway</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A358"><a href="/books/n/ce2/A358/" class="toc-item">VIII Meiotic Prophase Progression and Gametogenesis</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A361"><a href="/books/n/ce2/A361/" class="toc-item">IX Oocyte Development, Maturation, and Ovulation</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A368"><a href="/books/n/ce2/A368/" class="toc-item">X Future Prospects</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A369"><a href="/books/n/ce2/A369/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A370"><a href="/books/n/ce2/A370/" class="toc-item">Chapter 11. Spermatogenesis</a><div>Steven W L'Hernault.</div><ul id="toc_lst_NBK19997_A372" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A372"><a href="/books/n/ce2/A372/" class="toc-item">I Overview</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A374"><a href="/books/n/ce2/A374/" class="toc-item">II Organelle Morphogenesis During Spermatogenesis</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A384"><a href="/books/n/ce2/A384/" class="toc-item">III Spermiogenesis</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A387"><a href="/books/n/ce2/A387/" class="toc-item">IV Acquisition and Mechanism of Spermatozoan Motility</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A390"><a href="/books/n/ce2/A390/" class="toc-item">V Role of Motility During Oocyte Recognition</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A393"><a href="/books/n/ce2/A393/" class="toc-item">VI Future Prospects</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A394"><a href="/books/n/ce2/A394/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A395"><a href="/books/n/ce2/A395/" class="toc-item">Chapter 12. Male Development and Mating Behavior</a><div>Scott W Emmons and Paul W Sternberg.</div><ul id="toc_lst_NBK19997_A398" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A398"><a href="/books/n/ce2/A398/" class="toc-item">I Introduction and Overview of Male Anatomy</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A402"><a href="/books/n/ce2/A402/" class="toc-item">II Behavior</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A412"><a href="/books/n/ce2/A412/" class="toc-item">III Development</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A435"><a href="/books/n/ce2/A435/" class="toc-item">IV Concluding Remarks</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A436"><a href="/books/n/ce2/A436/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A437"><a href="/books/n/ce2/A437/" class="toc-item">Chapter 13. Fertilization and Establishment of Polarity in the Embryo</a><div>Kenneth J Kemphues and Susan Strome.</div><ul id="toc_lst_NBK19997_A440" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A440"><a href="/books/n/ce2/A440/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A447"><a href="/books/n/ce2/A447/" class="toc-item">II Fertilization</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A448"><a href="/books/n/ce2/A448/" class="toc-item">III Establishment of Polarity in the One-Cell Embryo</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A456"><a href="/books/n/ce2/A456/" class="toc-item">IV Cell Division Patterns in the Early Embryo</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A464"><a href="/books/n/ce2/A464/" class="toc-item">V Summary and Speculation</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A465"><a href="/books/n/ce2/A465/" class="toc-item">Chapter 14. Specification of Cell Fates in the Early Embryo</a><div>Ralf Schnabel and James R Priess.</div><ul id="toc_lst_NBK19997_A468" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A468"><a href="/books/n/ce2/A468/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A470"><a href="/books/n/ce2/A470/" class="toc-item">II Specification of Cell Fates in the AB Lineage</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A478"><a href="/books/n/ce2/A478/" class="toc-item">III Specification of the P<sub>1</sub> Descendants</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A484"><a href="/books/n/ce2/A484/" class="toc-item">IV Future Prospects</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A485"><a href="/books/n/ce2/A485/" class="toc-item">Chapter 15. Cell Death</a><div>Michael O Hengartner.</div><ul id="toc_lst_NBK19997_A487" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A487"><a href="/books/n/ce2/A487/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A488"><a href="/books/n/ce2/A488/" class="toc-item">II Programmed Cell Death in
<i>C. elegans</i>
</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A492"><a href="/books/n/ce2/A492/" class="toc-item">III Genetics of Programmed Cell Death</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A514"><a href="/books/n/ce2/A514/" class="toc-item">IV Programmed Cell Death in Specific Cell Types</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A520"><a href="/books/n/ce2/A520/" class="toc-item">V Cell Deaths not Mediated by the Common Death Program</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A524"><a href="/books/n/ce2/A524/" class="toc-item">VI Evolution of Programmed Cell Death</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A527"><a href="/books/n/ce2/A527/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A528"><a href="/books/n/ce2/A528/" class="toc-item">Chapter 16. Muscle: Structure, Function, and Development</a><div>Donald G Moerman and Andrew Fire.</div><ul id="toc_lst_NBK19997_A531" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A531"><a href="/books/n/ce2/A531/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A532"><a href="/books/n/ce2/A532/" class="toc-item">II The Organization, Structure, and Function of Muscle</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A563"><a href="/books/n/ce2/A563/" class="toc-item">III Specification of Muscle Patterns: Programs for Muscle Determination and
Differentiation</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A577"><a href="/books/n/ce2/A577/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A578"><a href="/books/n/ce2/A578/" class="toc-item">Chapter 17. Extracellular Matrix</a><div>James M Kramer.</div><ul id="toc_lst_NBK19997_A580" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A580"><a href="/books/n/ce2/A580/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A581"><a href="/books/n/ce2/A581/" class="toc-item">II Cuticle</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A611"><a href="/books/n/ce2/A611/" class="toc-item">III Basement Membranes</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A618"><a href="/books/n/ce2/A618/" class="toc-item">IV Conclusions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A619"><a href="/books/n/ce2/A619/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A620"><a href="/books/n/ce2/A620/" class="toc-item">Chapter 18. Heterochronic Genes</a><div>Victor Ambros.</div><ul id="toc_lst_NBK19997_A622" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A622"><a href="/books/n/ce2/A622/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A623"><a href="/books/n/ce2/A623/" class="toc-item">II Heterochronic Phenotypes</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A628"><a href="/books/n/ce2/A628/" class="toc-item">III Control of Larval Development by
<i>lin-14</i>
</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A633"><a href="/books/n/ce2/A633/" class="toc-item">IV Developmental Programs and Regulatory Targets</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A638"><a href="/books/n/ce2/A638/" class="toc-item">V Postdauer Reprogramming of Heterochronic Phenotypes</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A640"><a href="/books/n/ce2/A640/" class="toc-item">VI Perspectives</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A641"><a href="/books/n/ce2/A641/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A642"><a href="/books/n/ce2/A642/" class="toc-item">Chapter 19. Development of the Vulva</a><div>Iva Greenwald.</div><ul id="toc_lst_NBK19997_A644" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A644"><a href="/books/n/ce2/A644/" class="toc-item">I Introduction and Overview</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A646"><a href="/books/n/ce2/A646/" class="toc-item">II The Anchor Cell</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A653"><a href="/books/n/ce2/A653/" class="toc-item">III VPC Generation and Identity</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A657"><a href="/books/n/ce2/A657/" class="toc-item">IV VPC Specification</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A669"><a href="/books/n/ce2/A669/" class="toc-item">V Execution</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A673"><a href="/books/n/ce2/A673/" class="toc-item">VI Morphogenesis</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A677"><a href="/books/n/ce2/A677/" class="toc-item">VII Evolution of Vulval Development</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A678"><a href="/books/n/ce2/A678/" class="toc-item">VIII Future Prospects</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A679"><a href="/books/n/ce2/A679/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A680"><a href="/books/n/ce2/A680/" class="toc-item">Chapter 20. Patterning the Nervous System</a><div>Gary Ruvkun.</div><ul id="toc_lst_NBK19997_A682" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A682"><a href="/books/n/ce2/A682/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A684"><a href="/books/n/ce2/A684/" class="toc-item">II Invariant Cell Lineages in
<i>C. elegans</i>
Neurogenesis</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A686"><a href="/books/n/ce2/A686/" class="toc-item">III Specification of Sensory Neuronal Development</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A693"><a href="/books/n/ce2/A693/" class="toc-item">IV Generation of Reiterated Neurons by Reiterated Cell Lineages</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A699"><a href="/books/n/ce2/A699/" class="toc-item">V Spatial Patterning by the
<i>C. elegans</i>
HOM-C Gene Cluster</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A713"><a href="/books/n/ce2/A713/" class="toc-item">VI Concluding Remarks</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A714"><a href="/books/n/ce2/A714/" class="toc-item">Chapter 21. Cell and Growth Cone Migrations</a><div>Adam Antebi, Carolyn R Norris, Edward M Hedgecock, and Gian Garriga.</div><ul id="toc_lst_NBK19997_A717" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A717"><a href="/books/n/ce2/A717/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A718"><a href="/books/n/ce2/A718/" class="toc-item">II Neuroglia and Pioneers</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A725"><a href="/books/n/ce2/A725/" class="toc-item">III Netrins Guide Circumferential Migrations</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A727"><a href="/books/n/ce2/A727/" class="toc-item">IV Hierarchies Of Guidance Cues</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A728"><a href="/books/n/ce2/A728/" class="toc-item">V Genetic Requirements for Axonal Growth</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A732"><a href="/books/n/ce2/A732/" class="toc-item">VI Cell Migration and other Aspects of Cellular Phenotype</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A737"><a href="/books/n/ce2/A737/" class="toc-item">VII Muscle Positioning on the Body Wall and Muscle Arm Chemotropism</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A739"><a href="/books/n/ce2/A739/" class="toc-item">VIII Future Directions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A740"><a href="/books/n/ce2/A740/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A741"><a href="/books/n/ce2/A741/" class="toc-item">Chapter 22. Synaptic Transmission</a><div>James B Rand and Michael L Nonet.</div><ul id="toc_lst_NBK19997_A744" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A744"><a href="/books/n/ce2/A744/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A747"><a href="/books/n/ce2/A747/" class="toc-item">II Neurotransmitter Metabolism and Function</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A761"><a href="/books/n/ce2/A761/" class="toc-item">III Components Regulating Neurotransmitter Release in all Neurons</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A775"><a href="/books/n/ce2/A775/" class="toc-item">IV Conclusions and Future Perspectives</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A776"><a href="/books/n/ce2/A776/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A777"><a href="/books/n/ce2/A777/" class="toc-item">Chapter 23. Mechanotransduction</a><div>Monica Driscoll and Joshua Kaplan.</div><ul id="toc_lst_NBK19997_A780" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A780"><a href="/books/n/ce2/A780/" class="toc-item">I Introduction: the Neural Circuit For Locomotion</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A785"><a href="/books/n/ce2/A785/" class="toc-item">II Mechanosensory Control of Locomotion</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A797"><a href="/books/n/ce2/A797/" class="toc-item">III Touch Receptor Development and Differentiation</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A800"><a href="/books/n/ce2/A800/" class="toc-item">IV Genes Required for Touch Receptor Function</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A813"><a href="/books/n/ce2/A813/" class="toc-item">V Conclusions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A814"><a href="/books/n/ce2/A814/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A815"><a href="/books/n/ce2/A815/" class="toc-item">Chapter 24. Feeding and Defecation</a><div>Leon Avery and James H Thomas.</div><ul id="toc_lst_NBK19997_A818" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A818"><a href="/books/n/ce2/A818/" class="toc-item">I Introduction: Nematode Hydrostatics</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A820"><a href="/books/n/ce2/A820/" class="toc-item">II Feeding</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A840"><a href="/books/n/ce2/A840/" class="toc-item">III Defecation Motor Program</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A856"><a href="/books/n/ce2/A856/" class="toc-item">IV Conclusions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A859"><a href="/books/n/ce2/A859/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A860"><a href="/books/n/ce2/A860/" class="toc-item">Chapter 25. Chemotaxis and Thermotaxis</a><div>Cornelia I Bargmann and Ikue Mori.</div><ul id="toc_lst_NBK19997_A863" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A863"><a href="/books/n/ce2/A863/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A864"><a href="/books/n/ce2/A864/" class="toc-item">II
<i>C. elegans</i>
Responds to a Variety of Chemicals</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A866"><a href="/books/n/ce2/A866/" class="toc-item">III The Behavioral Mechanism of Chemotaxis and Thermotaxis</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A868"><a href="/books/n/ce2/A868/" class="toc-item">IV Cellular Analysis of Chemosensory and Thermosensory Neurons</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A871"><a href="/books/n/ce2/A871/" class="toc-item">V Genetic and Molecular Analysis of Chemosensation and Thermosensation</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A881"><a href="/books/n/ce2/A881/" class="toc-item">VI Regulation of Chemotaxis and Thermotaxis by Experience</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A882"><a href="/books/n/ce2/A882/" class="toc-item">VII Conclusions and Prospects</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A883"><a href="/books/n/ce2/A883/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A884"><a href="/books/n/ce2/A884/" class="toc-item">Chapter 26. Genetic and Environmental Regulation of Dauer Larva Development</a><div>Donald L Riddle and Patrice S Albert.</div><ul id="toc_lst_NBK19997_A886" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A886"><a href="/books/n/ce2/A886/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A888"><a href="/books/n/ce2/A888/" class="toc-item">II The Dauer State</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A893"><a href="/books/n/ce2/A893/" class="toc-item">III Developmental Transitions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A896"><a href="/books/n/ce2/A896/" class="toc-item">IV A Network of Gene Functions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A910"><a href="/books/n/ce2/A910/" class="toc-item">V Summary and Conclusions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A911"><a href="/books/n/ce2/A911/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A912"><a href="/books/n/ce2/A912/" class="toc-item">Chapter 27. Neural Plasticity</a><div>Erik M Jorgensen and Catharine Rankin.</div><ul id="toc_lst_NBK19997_A915" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A915"><a href="/books/n/ce2/A915/" class="toc-item">I Introduction: Connectivity and Plasticity</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A916"><a href="/books/n/ce2/A916/" class="toc-item">II Synaptic Plasticity During Development</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A924"><a href="/books/n/ce2/A924/" class="toc-item">III Behavioral Plasticity in the Adult</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A934"><a href="/books/n/ce2/A934/" class="toc-item">IV Conclusions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A935"><a href="/books/n/ce2/A935/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A936"><a href="/books/n/ce2/A936/" class="toc-item">Chapter 28. Environmental Factors and Gene Activities That Influence Life Span</a><div>Cynthia Kenyon.</div><ul id="toc_lst_NBK19997_A938" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A938"><a href="/books/n/ce2/A938/" class="toc-item">I The Study of Life Span</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A939"><a href="/books/n/ce2/A939/" class="toc-item">II Theories of Aging</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A946"><a href="/books/n/ce2/A946/" class="toc-item">III Aging in
<i>C. elegans</i>
</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A958"><a href="/books/n/ce2/A958/" class="toc-item">IV The Search for Genes that Control the Rate of Aging</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A970"><a href="/books/n/ce2/A970/" class="toc-item">V Prospects</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A971"><a href="/books/n/ce2/A971/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A972"><a href="/books/n/ce2/A972/" class="toc-item">Chapter 29. Evolution</a><div>David H A Fitch and W. Kelley Thomas.</div><ul id="toc_lst_NBK19997_A975" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A975"><a href="/books/n/ce2/A975/" class="toc-item">I Introduction</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A976"><a href="/books/n/ce2/A976/" class="toc-item">II Phylogenetic Context for
<i>C. elegans</i>
</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A985"><a href="/books/n/ce2/A985/" class="toc-item">III Character Evolution</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1005"><a href="/books/n/ce2/A1005/" class="toc-item">IV Other Directions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1006"><a href="/books/n/ce2/A1006/" class="toc-item">V Conclusions</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1007"><a href="/books/n/ce2/A1007/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A1008"><a href="/books/n/ce2/A1008/" class="toc-item">Chapter 30. Parasitic Nematodes</a><div>Mark Blaxter and David Bird.</div><ul id="toc_lst_NBK19997_A1011" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A1011"><a href="/books/n/ce2/A1011/" class="toc-item">I The Nematode World</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1013"><a href="/books/n/ce2/A1013/" class="toc-item">II An Introduction to Some Nematode Parasites</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1022"><a href="/books/n/ce2/A1022/" class="toc-item">III Antinematode Compounds and Their Targets</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1025"><a href="/books/n/ce2/A1025/" class="toc-item">IV The Nematode Surface</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1032"><a href="/books/n/ce2/A1032/" class="toc-item">V Parasite Genes and Genomes</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1035"><a href="/books/n/ce2/A1035/" class="toc-item">VI Future Prospects</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A1036"><a href="/books/n/ce2/A1036/" class="toc-item">Acknowledgments</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A3394"><a href="/books/n/ce2/A3394/" class="toc-item">Appendix 1 Genetics</a><div>Jonathan Hodgkin.</div><ul id="toc_lst_NBK19997_A3396" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A3396"><a href="/books/n/ce2/A3396/" class="toc-item">Part A Genetic Nomenclature</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A3408"><a href="/books/n/ce2/A3408/" class="toc-item">Part B List of Laboratory Strain and Allele Designations</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A3412"><a href="/books/n/ce2/A3412/" class="toc-item">Part C Skeleton Genetic Map</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A3413"><a href="/books/n/ce2/A3413/" class="toc-item">Part D List of Characterized Genes</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A3474"><a href="/books/n/ce2/A3474/" class="toc-item">Acknowledgments</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A3475"><a href="/books/n/ce2/A3475/" class="toc-item">Gene List</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A5911"><a href="/books/n/ce2/A5911/" class="toc-item">Appendix 2 Neurotransmitter Assignments for Specific Neurons</a><div>James B Rand and Michael L Nonet.</div></li><li class="half_rhythm" id="toc_itm_NBK19997_A5921"><a href="/books/n/ce2/A5921/" class="toc-item">Appendix 3 Codon Usage in <i>C. elegans</i></a><div>Paul M Sharp and Keith R Bradnam.</div></li><li class="half_rhythm" id="toc_itm_NBK19997_A5924"><a href="/books/n/ce2/A5924/" class="toc-item">Appendix 4 On-line <i>C. elegans</i> Resources</a><div>Mark L Edgley, Carolyn A Turner, and Donald L Riddle.</div><ul id="toc_lst_NBK19997_A5926" class="simple-list toc bktoc_lst_exp"><li class="half_rhythm" id="toc_itm_NBK19997_A5926"><a href="/books/n/ce2/A5926/" class="toc-item">Part A ACeDB Resources</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A5928"><a href="/books/n/ce2/A5928/" class="toc-item">Part B <b>
<i>C. elegans</i>
</b> Genome Project and Related Sources</a></li><li class="half_rhythm" id="toc_itm_NBK19997_A5930"><a href="/books/n/ce2/A5930/" class="toc-item">Part C Other Information Sources</a></li></ul></li><li class="half_rhythm" id="toc_itm_NBK19997_A1037"><a href="/books/n/ce2/A1037/" class="toc-item">Bibliography</a></li></ul><div class="bktoc_all_cntnr align_right" style="display:none"><ul class="inline_list_right"><li><a class="bktoc_all_exp" href="#">Expand All</a></li><li style="margin-left:.8em"><a class="bktoc_all_clps" href="#">Collapse All</a></li></ul></div></div></div></div>
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