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<script type="text/javascript" src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.boots.min.js"> </script><title>Microbial Ecology in States of Health and Disease - NCBI Bookshelf</title>
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<meta name="author" content="Forum on Microbial Health; Board on Global Health; Institute of Medicine">
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<meta name="citation_title" content="Microbial Ecology in States of Health and Disease">
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<meta name="citation_publisher" content="National Academies Press (US)">
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<meta name="citation_date" content="2014/02/18">
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<meta name="citation_author" content="Forum on Microbial Health">
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<meta name="citation_author" content="Board on Global Health">
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<meta name="citation_author" content="Institute of Medicine">
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<meta name="citation_doi" content="10.17226/18433">
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<meta name="DC.Title" content="Microbial Ecology in States of Health and Disease">
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<meta name="description" content="Individually and collectively, resident microbes play important roles in host health and survival. Shaping and shaped by their host environments, these microorganisms form intricate communities that are in a state of dynamic equilibrium. This ecologic and dynamic view of host-microbe interactions is rapidly redefining our view of health and disease. It is now accepted that the vast majority of microbes are, for the most part, not intrinsically harmful, but rather become established as persistent, co-adapted colonists in equilibrium with their environment, providing useful goods and services to their hosts while deriving benefits from these host associations. Disruption of such alliances may have consequences for host health, and investigations in a wide variety of organisms have begun to illuminate the complex and dynamic network of interaction - across the spectrum of hosts, microbes, and environmental niches - that influence the formation, function, and stability of host-associated microbial communities.">
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<meta name="og:description" content="Individually and collectively, resident microbes play important roles in host health and survival. Shaping and shaped by their host environments, these microorganisms form intricate communities that are in a state of dynamic equilibrium. This ecologic and dynamic view of host-microbe interactions is rapidly redefining our view of health and disease. It is now accepted that the vast majority of microbes are, for the most part, not intrinsically harmful, but rather become established as persistent, co-adapted colonists in equilibrium with their environment, providing useful goods and services to their hosts while deriving benefits from these host associations. Disruption of such alliances may have consequences for host health, and investigations in a wide variety of organisms have begun to illuminate the complex and dynamic network of interaction - across the spectrum of hosts, microbes, and environmental niches - that influence the formation, function, and stability of host-associated microbial communities.">
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<span itemprop="author">Board on Global Health</span>; <span itemprop="author">Institute of Medicine</span>.</p><div class="half_rhythm">Washington (DC): <a href="http://www.nap.edu/" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">National Academies Press (US)</span></a>; <span itemprop="datePublished">2014 Feb 18</span>.<div class="small"><span class="label">ISBN-13: <span itemprop="isbn">978-0-309-29062-3</span></span>ISBN-10: <span itemprop="isbn">0-309-29062-7</span></div></div><div><a href="/books/about/copyright/">Copyright</a> 2014 by the National Academy of Sciences. All rights
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reserved.</div><div class="small half_rhythm bk_noprnt"><a href="http://www.nap.edu/catalog.php?record_id=18433" ref="pagearea=body&targetsite=external&targetcat=link&targettype=publisher">Hardcopy Version at National Academies Press</a></div><a class="btn wsprkl bkr_rd" href="/books/n/nap18433/sec_001/?report=reader">Read</a></div><div class="bkr_clear"></div></div><div class="bkr_bottom_sep bkr_bottom_margin body-content whole_rhythm"><div itemprop="description"><p>Individually and collectively, resident microbes play important roles in host health
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and survival. Shaping and shaped by their host environments, these microorganisms
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form intricate communities that are in a state of dynamic equilibrium. This ecologic
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and dynamic view of host-microbe interactions is rapidly redefining our view of
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health and disease. It is now accepted that the vast majority of microbes are, for
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the most part, not intrinsically harmful, but rather become established as
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persistent, co-adapted colonists in equilibrium with their environment, providing
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useful goods and services to their hosts while deriving benefits from these host
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associations. Disruption of such alliances may have consequences for host health,
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and investigations in a wide variety of organisms have begun to illuminate the
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complex and dynamic network of interaction - across the spectrum of hosts, microbes,
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and environmental niches - that influence the formation, function, and stability of
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host-associated microbial communities.</p><p>
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<i>Microbial Ecology in States of Health and Disease</i> is the summary of
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a workshop convened by the Institute of Medicine's Forum on Microbial Threats in
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March 2013 to explore the scientific and therapeutic implications of microbial
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ecology in states of health and disease. Participants explored host-microbe
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interactions in humans, animals, and plants; emerging insights into how microbes may
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influence the development and maintenance of states of health and disease; the
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effects of environmental change(s) on the formation, function, and stability of
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microbial communities; and research challenges and opportunities for this emerging
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field of inquiry.</p></div></div></div><div class="fm-sec"><div><p>Rapporteurs: Eileen R. Choffnes, Leigh Anne Olsen, and Alison Mack.</p></div><div><p>Financial support for this activity was provided by
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the U.S. Department of Health and Human Services: National Institutes of Health,
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National Institute of Allergy and Infectious Diseases, Centers for Disease Control
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and Prevention, Food and Drug Administration, and the Fogarty International Center;
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U.S. Department of Defense: Armed Forces Health Surveillance Center, Defense Threat
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Reduction Agency, and Medical Research and Materiel Command; U.S. Department of
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Justice: Federal Bureau of Investigation; U.S. Department of Veterans Affairs; U.S.
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Department of Homeland Security; U.S. Agency for International Development;
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Uniformed Services University of the Health Sciences; Alfred P. Sloan Foundation;
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American Society for Microbiology; Burroughs Wellcome Fund; GlaxoSmithKline;
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Infectious Diseases Society of America; Johnson & Johnson; Merck Company
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Foundation; and sanofi pasteur. The views presented in this publication do not
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necessarily reflect the views of the organizations or agencies that provided support
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for this activity.</p></div><div><h4 class="inline">Suggested citation:</h4><p>IOM (Institute of Medicine). 2014. Microbial ecology
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in states of health and disease: Workshop summary. Washington, DC: The National
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Academies Press.</p></div><div><p>NOTICE: The workshop that is the subject of this workshop summary was approved by the
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Governing Board of the National Research Council, whose members are drawn from the
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councils of the National Academy of Sciences, the National Academy of Engineering,
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and the Institute of Medicine.</p></div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> 2014 by the National Academy of Sciences. All rights
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reserved.</div><div class="small"><span class="label">Bookshelf ID: NBK184832</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/24555208" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">24555208</a></span>DOI: <a href="http://dx.crossref.org/10.17226/18433" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">10.17226/18433</a></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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