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Some of the 2009 recommendations have been retained in the new guideline. This 2009 full guideline includes the evidence supporting the 2009 recommendations. Information that has been replaced by the new guideline has been shaded in grey in the PDF.</strong></p><div class="main-content lit-style"><div class="fm-sec bkr_bottom_sep"><div class="bkr_thumb"><a href="http://www.wales.nhs.uk/sites3/home.cfm?OrgID=432" title="National Collaborating Centre for Cancer (UK)" class="img_link icnblk_img" ref="pagearea=logo&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-nicecg80-lrg.png" alt="Cover of Early and Locally Advanced Breast Cancer" /></a></div><div class="bkr_bib"><h1 id="_NBK11643_"><span itemprop="name">Early and Locally Advanced Breast Cancer</span></h1><div class="subtitle">Diagnosis and Treatment</div><p><i>NICE Clinical Guidelines, No. 80</i></p><p class="contrib-group"><h4>Authors</h4><span itemprop="author">National Collaborating Centre for Cancer (UK)</span>.</p><div class="half_rhythm">Cardiff (UK): <a href="http://www.wales.nhs.uk/sites3/home.cfm?OrgID=432" ref="pagearea=meta&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher"><span itemprop="publisher">National Collaborating Centre for Cancer (UK)</span></a>; <span itemprop="datePublished">2009 Feb</span>.<div class="small">ISBN-13: <span itemprop="isbn">978-0-9558265-2-8</span></div></div><div><a href="/books/about/copyright/">Copyright</a> &#x000a9; 2009, National Collaborating Centre for Cancer.</div><a class="btn wsprkl bkr_rd" href="/books/n/nicecg80/foreword/?report=reader">Read</a></div><div class="bkr_clear"></div></div><div class="bkr_bottom_sep bkr_bottom_margin body-content whole_rhythm"><div itemprop="description"><h2>Excerpt</h2><p><b>Update Information:</b> In July 2018 we updated and replaced this guideline with NICE guideline NG101 on early and locally advanced breast cancer.</p><p>Breast cancer is the most common cancer in women and its management often presents patients
and their healthcare professionals with difficult decisions about the most appropriate
treatment. For all those affected by breast cancer (including family and carers) it is
important to recognise the impact of this diagnosis, the complexity of treatment options and
the wide ranging needs and support required throughout this period of care and beyond. We
hope that this document will provide helpful and appropriate guidance to both healthcare
professionals and patients on the diagnosis and subsequent management of early and locally
advanced breast cancer.</p></div></div></div><div class="fm-sec"><div><p>This guideline updates and replaces NICE technology appraisal guidance 109 (docetaxel), 108 (paclitaxel) and 107 (trastuzumab).</p></div><div><p>Full Guideline developed for NICE</p><p>Five NICE guidelines have been included on the Bookshelf as part of a pilot
project. All NICE guidance is available on the NICE website at <a href="http://www.nice.org.uk/" ref="pagearea=body&amp;targetsite=external&amp;targetcat=link&amp;targettype=uri">www<wbr style="display:inline-block"></wbr>&#8203;.nice.org.uk</a></p></div><div><p>While every effort has been made to ensure the accuracy of the information contained within this publication, the publisher can give no guarantee for information about drug dosage and application thereof contained in this book. In every individual case the respective user must check current indications and accuracy by consulting other pharmaceutical
literature and following the guidelines laid down by the manufacturers of specific products and the relevant authorities
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