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We launched the Biomedical Data Translator program as a multiyear, iterative effort toward the eventual development of a comprehensive and relational “data translator” that combines multiple types of existing data sources.
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<a href="/research/research-activities/translator/about" class="first" data-drupal-link-system-path="node/27701">About Biomedical Data Translator</a>
|
||
</li>
|
||
<li>
|
||
<a href="/research/research-activities/translator/performance-phase-qa" data-drupal-link-system-path="node/44092">Biomedical Data Translator Performance Phase — Questions and Answers</a>
|
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</li>
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<a href="/research/research-activities/translator/faqs" data-drupal-link-system-path="node/27700">Frequently Asked Questions</a>
|
||
</li>
|
||
<li class="last">
|
||
<a href="/research/research-activities/translator/projects" class="last" data-drupal-link-system-path="node/27661">Translator Projects</a>
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|
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|
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</style><div class="alert alert-info d-inline-block" style="text-align:center;width:100%;"><strong>A new funding opportunity for Translator is available. See the Funding Opportunities section for more details.</strong></div><h2 class="section-header">Building a Data Translator</h2><div class="contact-box"><h4>Contact</h4><p><a href="mailto:translator-questions@nih.gov">Translator Program staff</a></p></div><p>As a result of recent scientific advances, a tremendous amount of data is available from biomedical research and clinical interactions with patients, health records, clinical trials and adverse event reports that could be useful for understanding health and disease and for developing and identifying treatments for diseases. Ideally, these data would be mined collectively to provide insights into the relationship between molecular and cellular processes (the targets of rational drug design) and the signs and symptoms of diseases. Currently, these very rich yet different data sources are housed in various locations, often in forms that are not compatible or interoperable with each other. All of these factors limit the ability to get more treatments to all people more quickly. </p><p>To address these problems, we launched the Biomedical Data Translator program, called “Translator” for short. This multiyear, iterative effort will culminate in the development of a comprehensive, relational, N-dimensional Biomedical Data Translator that integrates multiple types of existing data sources, including objective signs and symptoms of disease, drug effects and intervening types of biological data relevant to understanding pathophysiology.</p>
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<div class="container news-content Advancing">
|
||
<h2 class="section-heading">Biomedical Data Translator News</h2>
|
||
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||
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<div class="paragraph paragraph--type--view paragraph--view-mode--default">
|
||
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<div class="views-element-container"><div class="row col js-view-dom-id-008ab755b766b51697ff0ba438870a4be1846f24d32324972f5c61539722413c">
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<div class="views-element-container"><div class="row col js-view-dom-id-6b1e78fe06a3b10056b6552198bf1b2530320799b96feeb2d448c6e3203b89b5">
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</div>
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||
<div class="col-sm-4 mb-4 views-row"><div class="usa-card__container">
|
||
<div class="usa-card__body">
|
||
<h3 class="title">Can AI Shake-Up Translational Research?</h3>
|
||
<p class="m-0"><i>October 16, 2024 - Media Coverage</i>
|
||
</p>
|
||
<ul class="list-pipe">
|
||
<li><i>Biomedical Data Translator (Translator)</i></li>
|
||
</ul>
|
||
|
||
</div>
|
||
<div class="usa-card__footer">
|
||
<a href="https://www.nature.com/articles/d41586-024-03318-0">Read Article</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div class="col-sm-4 mb-4 views-row"><div class="usa-card__container">
|
||
<div class="usa-card__body">
|
||
<h3 class="title">FDA Using AI in Drug Surveillance; Health Systems Move Ahead With AI; RAISE Guidance</h3>
|
||
<p class="m-0"><i>February 29, 2024 - Media Coverage</i>
|
||
</p>
|
||
<ul class="list-pipe">
|
||
<li><i>Biomedical Data Translator (Translator)</i></li>
|
||
</ul>
|
||
|
||
</div>
|
||
<div class="usa-card__footer">
|
||
<a href="https://www.medpagetoday.com/special-reports/features/108954">Read Article</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div class="col-sm-4 mb-4 views-row"><div class="usa-card__container">
|
||
<div class="usa-card__body">
|
||
<h3 class="title">Data Science Tools Will Speed Rare Disease Solutions</h3>
|
||
<p class="m-0"><i>March 15, 2023 - Grantee/Partner News</i>
|
||
</p>
|
||
<ul class="list-pipe">
|
||
<li><i>ASPIRE</i></li>
|
||
<li><i>Biomedical Data Translator (Translator)</i></li>
|
||
<li><i>Genetic and Rare Diseases (GARD) Information Center</i></li>
|
||
</ul>
|
||
|
||
</div>
|
||
<div class="usa-card__footer">
|
||
<a href="https://nlmdirector.nlm.nih.gov/2023/03/15/data-science-tools-will-speed-rare-disease-solutions/">Read Article</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
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||
|
||
</div>
|
||
|
||
<div class="text-center button-wrap">
|
||
<button class="buttons btn-1 mt-4"><a href="/news-events/news?program%5B0%5D=Biomedical%20Data%20Translator%20%28Translator%29">See More Translator News</a></button>
|
||
</div>
|
||
|
||
|
||
<hr class="section-divider">
|
||
</div>
|
||
</section>
|
||
<section>
|
||
<div class="container news-content Advancing">
|
||
|
||
|
||
<div class="row vertical-line two-col">
|
||
<div class="col-xl-6 col-wrap">
|
||
<div class="pe-lg-4 p-0 col">
|
||
|
||
|
||
<h2>Translator Process</h2>
|
||
<img src="/sites/default/files/2023-09/NCATS_TranslatorInfographic_v2%20FINAL.jpg" class="w-100 mt-2">
|
||
<div class="description pt-4">
|
||
|
||
<p><strong>Translator Draft Architecture. </strong>A researcher will be able to use NCATS Biomedical Data Translator to request specific biomedical information. For example: “predict treatments for disease Y.” The query will be sent to Translator’s Autonomous Relay Agents (ARAs) to determine how best to answer the query. The ARA will break the query into smaller tasks that are transmitted to rich, specialty knowledge bases called Knowledge Providers (KPs). This process will be iterative, such that the ARAs and KPs can build on information from the others. Researchers will be able to explore this distilled knowledge and help them to develop new research hypotheses that lead to new scientific discoveries!</p>
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="col-xl-6 col-wrap">
|
||
<div class="ps-lg-4 p-0 col">
|
||
|
||
|
||
<h2>Funding Opportunities</h2>
|
||
<img src="/sites/default/files/2024-07/Translator-Graphic-2024-Bold_620x275_P1.png" class="w-100 mt-2">
|
||
<div class="description pt-4">
|
||
|
||
<p id="funding-opportunities">A new research opportunity announcement (ROA) soliciting applications for research projects to support the continued development of the Biomedical Data Translator is available. This opportunity utilizes the Other Transactions Authority funding mechanism and has a compressed timeline. Applications will be due on Aug. 28, 2024, with an optional letter of intent due on Aug. 15, 2024.</p><p id="funding-opportunities">PLEASE NOTE: An updated version of the ROA was uploaded on July 30, 2024, which includes clarifying text regarding user engagement expectations. Please review the updated ROA.</p><p>Read the <em>updated</em> <a href="https://ncats.nih.gov/sites/default/files/2024-07/NCATS-Translator-FY24-ROA-508.pdf">ROA and instructions on how to apply</a>.</p><p>View <a href="/research/research-activities/translator/performance-phase-qa">questions and answers</a> about this funding opportunity.</p>
|
||
</div>
|
||
|
||
<div class="text-center button-wrap">
|
||
<button class="buttons btn-1 mt-4"><a href="/funding/funding-opportunities?keyword=%22biomedical%20data%20translator%22">Learn More About Funding Opportunities</a></button>
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<hr class="section-divider">
|
||
</div>
|
||
</section>
|
||
<section>
|
||
<div class="container news-content Advancing">
|
||
<h2 class="section-heading">More About the Program</h2>
|
||
|
||
|
||
<div class="row mb-4 three-pic-cards">
|
||
|
||
|
||
<div class="col-xl-4 ps-xl-3 mb-4">
|
||
<div class="card border-0 p-0 radius-10 h-100">
|
||
<div class="row p-20 g-4 align-items-stretch">
|
||
<div class="col-xl-12 col-lg-6">
|
||
<img src="/sites/default/files/2023-09/Translator%201_746x370.png" class="img-fluid">
|
||
</div>
|
||
<div class="col-xl-12 col-lg-6">
|
||
<div class="card-body px-0 pt-0">
|
||
<h3 class="">About Biomedical Data Translator</h3>
|
||
<p class="py-xl-0 py-lg-4 py-md-4 py-sm-4 py-2">
|
||
|
||
<p>We provide more information about Translator and its objectives.</p>
|
||
|
||
</p>
|
||
</div>
|
||
<div class="card-footer bg-white border-0 p-0">
|
||
<a href="/research/research-activities/translator/about">Learn More</a>
|
||
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||
</div>
|
||
</div>
|
||
</div>
|
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<div class="col-xl-4 ps-xl-3 mb-4">
|
||
<div class="card border-0 p-0 radius-10 h-100">
|
||
<div class="row p-20 g-4 align-items-stretch">
|
||
<div class="col-xl-12 col-lg-6">
|
||
<img src="/sites/default/files/2023-09/Translator%203_746x340.png" class="img-fluid">
|
||
</div>
|
||
<div class="col-xl-12 col-lg-6">
|
||
<div class="card-body px-0 pt-0">
|
||
<h3 class="">Translator Frequently Asked Questions</h3>
|
||
<p class="py-xl-0 py-lg-4 py-md-4 py-sm-4 py-2">
|
||
|
||
<p>We have answers to frequently asked questions about the Biomedical Data Translator program. </p>
|
||
|
||
</p>
|
||
</div>
|
||
<div class="card-footer bg-white border-0 p-0">
|
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<a href="/research/research-activities/translator/faqs">Learn More</a>
|
||
</div>
|
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</div>
|
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|
||
</div>
|
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</div>
|
||
</div>
|
||
<div class="col-xl-4 ps-xl-3 mb-4">
|
||
<div class="card border-0 p-0 radius-10 h-100">
|
||
<div class="row p-20 g-4 align-items-stretch">
|
||
<div class="col-xl-12 col-lg-6">
|
||
<img src="/sites/default/files/2023-09/Translator%202_746x370.png" class="img-fluid">
|
||
</div>
|
||
<div class="col-xl-12 col-lg-6">
|
||
<div class="card-body px-0 pt-0">
|
||
<h3 class="">Translator Projects</h3>
|
||
<p class="py-xl-0 py-lg-4 py-md-4 py-sm-4 py-2">
|
||
|
||
<p class="MsoNormal" style="line-height:137%;"><span style="color:#0A0A0A;line-height:137%;mso-bidi-font-size:6.0pt;mso-font-width:105%;">We are developing</span><span style="color:#0A0A0A;line-height:137%;mso-bidi-font-size:6.0pt;mso-font-width:105%;mso-spacerun:yes;"> </span><span style="color:#0A0A0A;line-height:137%;mso-bidi-font-size:6.0pt;mso-font-width:105%;">Translator to integrate the vast amounts of currently available medical research data and accelerate the development of new treatments.</span><o:p></o:p></p>
|
||
|
||
</p>
|
||
</div>
|
||
<div class="card-footer bg-white border-0 p-0">
|
||
<a href="/research/research-activities/translator/projects">Learn More</a>
|
||
</div>
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||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
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</section>
|
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|
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|
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</div>
|
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<div class="block block-layout-builder block-extra-field-blocknodelanding-page-new-content-moderation-control">
|
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|
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|
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|
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</div>
|
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</div>
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</div>
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|
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</article>
|
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|
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</div>
|
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<div id="block-footercss" class="block block-block-content block-block-content2db33373-6fb7-49c5-be2f-83266eddea39">
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<div class="container"><p class="last-update-container">Last updated on October 11, 2024</p></div>
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