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<span>DHEA Sulfate Test</span>
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<h1>DHEA Sulfate Test</h1>
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<section><div class="mp-content"><h2>What is a DHEA sulfate test?</h2>
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<p>This test measures the levels of DHEA sulfate (DHEAS) in your blood. DHEAS stands for dehydroepiandrosterone sulfate. DHEAS is mostly made in the adrenal glands, two small glands located above your kidneys. Your adrenal glands help control your heart rate, blood pressure, and other body functions. They make different types of <a data-tid="1499" href="https://medlineplus.gov/hormones.html">hormones</a> you need to stay healthy. This includes cortisol, a hormone that helps with your <a data-tid="295" href="https://medlineplus.gov/immunesystemanddisorders.html">immune system</a>, and DHEAS, a steroid hormone.</p>
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<p>DHEAS is a type of androgen (male sex hormone), but it's found in both men and women. Smaller amounts of DHEAS are made in the testicles and ovaries.</p>
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<p>DHEAS plays an important role in making the male sex hormone testosterone and the female sex hormone estrogen. DHEAS helps with the development of male sexual characteristics at <a data-tid="5569" href="https://medlineplus.gov/puberty.html">puberty</a> and reproduction for both sexes. Your DHEAS levels peak around puberty and then get lower as you age.</p>
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<p>If your DHEAS levels are not normal, it may mean there is a problem with your <a data-tid="128" href="https://medlineplus.gov/adrenalglanddisorders.html">adrenal glands</a> or sex hormones (estrogen or testosterone).</p>
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<p>Other names: DHEAS, DHEA-S, DHEA, DHEA-SO4, dehydroepiandrosterone sulfate</p></div>
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</section>
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<section><div class="mp-content"><h2>What is it used for?</h2>
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<p>A DHEA sulfate (DHEAS) test is most often used to:</p>
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<ul>
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<li>Find out if your adrenal glands are working well</li>
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<li>Diagnose tumors of the adrenal glands</li>
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<li>Diagnose disorders of the <a data-tid="4280" href="https://medlineplus.gov/testiculardisorders.html">testicles</a> or <a data-tid="5804" href="https://medlineplus.gov/ovariandisorders.html">ovaries</a></li>
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<li>Find out the cause of early or late puberty in boys</li>
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<li>Look for the cause of the development of masculine features in women and girls, including excess body and facial hair growth and deepening of voice</li>
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</ul>
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<p>A DHEAS test is often done along with other sex hormone tests. These include <a data-pid="782" href="https://medlineplus.gov/lab-tests/testosterone-levels-test/">testosterone tests</a> for men and <a data-pid="881" href="https://medlineplus.gov/lab-tests/estrogen-levels-test/">estrogen tests</a> for women.</p></div>
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</section>
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<section><div class="mp-content"><h2>Why do I need a DHEA sulfate test?</h2>
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<p>You may need this test if you have symptoms of high or low levels of DHEA sulfate (DHEAS). Men may not have any symptoms of high levels of DHEAS.</p>
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<p>Symptoms of <strong>high levels of DHEAS</strong> in women and girls may include:</p>
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<ul>
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<li>Excess body and facial hair growth</li>
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<li>Deepening of voice</li>
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<li><a data-tid="325" href="https://medlineplus.gov/menstruation.html">Menstrual</a> irregularities</li>
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<li><a data-tid="124" href="https://medlineplus.gov/acne.html">Acne</a></li>
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<li>Becoming very muscular</li>
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<li><a data-tid="5282" href="https://medlineplus.gov/hairloss.html">Hair loss</a> at the top of the head</li>
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</ul>
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<p>Baby girls may also need testing if they have external (outer) genitals that do not look clearly male or female (ambiguous genitalia). Boys may need this test if they have signs of early puberty.</p>
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<p><strong>Low levels of DHEAS</strong> may have different causes. If the cause of low levels of DHEAS is an adrenal gland disorder, the symptoms can include:</p>
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<ul>
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<li>Unexplained weight loss</li>
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<li><a data-tid="489" href="https://medlineplus.gov/nauseaandvomiting.html">Nausea and vomiting</a></li>
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<li><a data-tid="216" href="https://medlineplus.gov/dizzinessandvertigo.html">Dizziness</a></li>
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<li><a data-tid="6051" href="https://medlineplus.gov/dehydration.html">Dehydration</a></li>
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<li>Craving for salt</li>
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</ul>
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<p>If the cause of low levels of DHEAS is related to aging, the symptoms can include:</p>
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<ul>
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<li>Decreased sex drive</li>
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<li><a data-tid="118" href="https://medlineplus.gov/erectiledysfunction.html">Erectile dysfunction</a> in men</li>
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<li>Thinning of vaginal tissues in women</li>
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</ul></div>
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</section>
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<section><div class="mp-content"><h2>What happens during a DHEA sulfate test?</h2>
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<p>A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.</p></div>
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</section>
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<section><div class="mp-content"><h2>Will I need to do anything to prepare for the test?</h2>
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<p>You don't need any special preparations for a DHEA sulfate test.</p></div>
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</section>
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<section><div class="mp-content"><h2>Are there any risks to the test?</h2>
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<p>There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.</p></div>
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</section>
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<section><div class="mp-content"><h2>What do the results mean?</h2>
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<p>If your results show <strong>high levels of DHEAS</strong>, it may be a sign of the following conditions:</p>
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<ul>
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<li>Congenital adrenal hyperplasia, an inherited disorder of the adrenal glands in which the adrenal glands produce too many male sex hormones.</li>
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<li>A tumor of the adrenal gland. It may be <a data-tid="3585" href="https://medlineplus.gov/benigntumors.html">benign</a> (noncancerous) or cancerous.</li>
|
||
<li><a data-tid="5912" href="https://medlineplus.gov/polycysticovarysyndrome.html">Polycystic ovary syndrome</a> (PCOS). PCOS is a common hormone disorder affecting childbearing women. It is one of the leading causes of <a data-tid="5654" href="https://medlineplus.gov/femaleinfertility.html">female infertility</a>.</li>
|
||
<li>In rare cases, a high level of DHEAS could be a sign of an ovarian tumor.</li>
|
||
</ul>
|
||
<p>If your results show <strong>low levels of DHEAS</strong>, it may be a sign of the following conditions:</p>
|
||
<ul>
|
||
<li><a data-tid="1233" href="https://medlineplus.gov/addisondisease.html">Addison disease</a>. Addison disease is a disorder in which the adrenal glands are not able to make enough of certain hormones.</li>
|
||
<li><a data-tid="362" href="https://medlineplus.gov/pituitarydisorders.html">Hypopituitarism</a>, a condition in which the pituitary gland does not make enough of one or more of the pituitary hormones. The possible symptoms will vary, depending on which hormones are lacking.</li>
|
||
</ul>
|
||
<p>If you have questions about your results, talk to your provider. To understand the results of a DHEA sulfate test, your provider will consider your symptoms, age, sex, medical history, and the results of other blood tests.</p>
|
||
<p>Learn more about <a data-pid="806" href="https://medlineplus.gov/lab-tests/how-to-understand-your-lab-results/">laboratory tests, reference ranges, and understanding results</a>.</p></div>
|
||
</section>
|
||
|
||
<section><div class="mp-content"><h2>Is there anything else I need to know about a DHEA sulfate test?</h2>
|
||
<p>Over-the-counter DHEA sulfate <a data-tid="3538" href="https://medlineplus.gov/dietarysupplements.html">supplements</a> are available and are sometimes promoted as an anti-aging therapy. However, there is no reliable evidence to support these anti-aging claims. In fact, these supplements may cause serious side effects. If you have questions about DHEA supplements, talk to your provider.</p></div>
|
||
</section>
|
||
|
||
<section><div class="mp-refs mp-content"><h2>References</h2>
|
||
<ol>
|
||
<li>Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2023. Adrenal Disorders; [reviewed 2021 Jun 07; cited 2024 Feb 16]; [about 8 screens]. Available from: <a href="https://my.clevelandclinic.org/health/diseases/16717-adrenal-disorders" target="bibliowin">https://my.clevelandclinic.org/health/diseases/16717-adrenal-disorders</a></li>
|
||
<li>Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2023. Blood Tests; [reviewed 2022 Dec 06; cited 2023 Dec 21]; [about 16 screens]. Available from: <a href="https://my.clevelandclinic.org/health/diagnostics/24508-blood-tests" target="bibliowin">https://my.clevelandclinic.org/health/diagnostics/24508-blood-tests</a></li>
|
||
<li>Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2023. DHEAS Test (DHEA Sulfate Test); [reviewed 2021 Nov 24; cited 2024 Feb 15]; [about 16 screens]. Available from: <a href="https://my.clevelandclinic.org/health/diagnostics/22148-dheas-test-dhea-sulfate-test" target="bibliowin">https://my.clevelandclinic.org/health/diagnostics/22148-dheas-test-dhea-sulfate-test</a></li>
|
||
<li>Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2023. Intersex; [reviewed 2022 Jul 19; cited 2024 Feb 21]; [about 5 screens]. Available from: <a href="https://my.clevelandclinic.org/health/articles/16324-intersex" target="bibliowin">https://my.clevelandclinic.org/health/articles/16324-intersex</a></li>
|
||
<li>Labcorp [Internet]. Burlington (NC): Laboratory Corporation of America(r) Holdings; c2023. Patient Test Information: Dehydroepiandrosterone (DHEA) Sulfate; [cited 2024 Feb 15]; [about 6 screens]. Available from: <a href="https://www.labcorp.com/tests/004020/dehydroepiandrosterone-dhea-sulfate" target="bibliowin">https://www.labcorp.com/tests/004020/dehydroepiandrosterone-dhea-sulfate</a></li>
|
||
<li>Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998-20234. Ambiguous Genitalia: Symptoms and causes; 2018 Apr 18 [cited 2023 Dec 21]; [about 10 screens]. Available from: <a href="https://www.mayoclinic.org/diseases-conditions/ambiguous-genitalia/symptoms-causes/syc-20369273" target="bibliowin">https://www.mayoclinic.org/diseases-conditions/ambiguous-genitalia/symptoms-causes/syc-20369273</a></li>
|
||
<li>Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998-2023. DHEA; 2023 Aug 10 [cited 2023 Dec 21]; [about 4 screens]. Available from: <a href="https://www.mayoclinic.org/drugs-supplements-dhea/art-20364199" target="bibliowin">https://www.mayoclinic.org/drugs-supplements-dhea/art-20364199</a></li>
|
||
<li>Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998-2023. Hypopituitarism; 2024 Feb 13 [cited 2024 Feb 16]; [about 6 screens]. Available from: <a href="https://www.mayoclinic.org/diseases-conditions/hypopituitarism/symptoms-causes/syc-20351645" target="bibliowin">https://www.mayoclinic.org/diseases-conditions/hypopituitarism/symptoms-causes/syc-20351645</a></li>
|
||
<li>Nemours KidsHealth [Internet]. Jacksonville (FL): The Nemours Foundation; c1995-2023. Blood Test: Dehydroepiandrosterone-Sulfate (DHEA-S); [reviewed 2023 May; cited 2023 Dec 21]; [about 3 screens]. Available from: <a href="https://kidshealth.org/en/parents/test-dheas.html" target="bibliowin">https://kidshealth.org/en/parents/test-dheas.html</a></li>
|
||
<li>Testing.com [Internet]. Seattle (WA): OneCare Media; c2023. Adrenal Gland; [cited 2023 Dec 21]; [about 1 screen]. Available from: <a href="https://www.testing.com/glossary/#adrenal-gland" target="bibliowin">https://www.testing.com/glossary/#adrenal-gland</a></li>
|
||
<li>Testing.com [Internet]. Seattle (WA): OneCare Media; c2023. Benign; [cited 2023 Dec 21]; [about 1 screen]. Available from: <a href="https://www.testing.com/glossary/#benign" target="bibliowin">https://www.testing.com/glossary/#benign</a></li>
|
||
<li>Testing.com [Internet]. Seattle (WA): OneCare Media; c2023. DHEA-S Test; [modified 2023 Jan 5; cited 2023 Dec 21]; [about 9 screens]. Available from: <a href="https://www.testing.com/tests/dheas/" target="bibliowin">https://www.testing.com/tests/dheas/</a></li>
|
||
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|
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<li><a href="https://medlineplus.gov/addisondisease.html">Addison Disease</a></li>
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<li><a href="https://medlineplus.gov/adrenalglanddisorders.html">Adrenal Gland Disorders</a></li>
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"headline": "DHEA Sulfate Test",
|
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"description": "This test measures the levels of DHEA sulfate (DHEAS) in your blood. DHEAS stands for dehydroepiandrosterone sulfate. DHEAS is mostly made in the adrenal glands, two small glands located above your kidneys. Your adrenal glands help control your heart rate, blood pressure, and other body functions. They make different types of hormones you need to stay healthy. This includes cortisol, a hormone that helps with your immune system, and DHEAS, a steroid hormone. DHEAS is a type of androgen (male sex hormone), but it's found in both men and women. Smaller amounts of DHEAS are made in the testicles and ovaries. DHEAS plays an important role in making the male sex hormone testosterone and the female sex hormone estrogen. DHEAS helps with the development of male sexual characteristics at puberty and reproduction for both sexes. Your DHEAS levels peak around puberty and then get lower as you age. If your DHEAS levels are not normal, it may mean there is a problem with your adrenal glands or sex hormones (estrogen or testosterone). Other names: DHEAS, DHEA-S, DHEA, DHEA-SO4, dehydroepiandrosterone sulfate",
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