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</div><div><span>ALP - blood test</span></div></div>
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</a><h1 class="with-also" itemprop="name">ALP - blood test</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, <a test="test" href="./002237.htm">bile</a> ducts, and bone.</p><p>A blood test can be done to measure the level of ALP.</p><p>A related test is the <a test="test" href="./003497.htm">ALP isoenzyme test</a>. </p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>A blood sample is needed. Most of the time, blood is <a test="test" href="./003423.htm">drawn from a vein</a> located on the inside of the elbow or the back of the hand. </p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How to Prepare for the Test</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Many medicines can interfere with blood test results.</p><ul><li>Your health care provider will tell you if you need to stop taking any medicines before you have this test.</li><li>DO NOT stop or change your medicines without talking to your provider first.</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test will Feel</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>You may feel slight pain or a sting when the needle is inserted. You may also feel some throbbing at the site after the blood is drawn.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Why the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>This test may be done:</p><ul><li>To diagnose liver or bone disease</li><li>To check if treatments for those diseases are working</li><li>To check for side effects from medicines</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Normal Results</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (µkat/L).</p><p>Normal values may vary slightly from laboratory to laboratory. They also can vary with age and sex. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women.</p><p>The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>What Abnormal Results Mean</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>Abnormal results may be due to the following conditions:</p><p>Higher-than-normal ALP levels</p><ul><li><a test="test" href="./000263.htm">Biliary obstruction</a></li><li>Bone disease</li><li>Eating a fatty meal if you have blood type O or B</li><li>Healing fracture</li><li><a test="test" href="./001154.htm">Hepatitis</a></li><li><a test="test" href="./001215.htm">Hyperparathyroidism</a></li><li>Hyperthyroidism</li><li>Leukemia</li><li>Liver disease</li><li>Lymphoma</li><li>Osteoblastic bone tumors</li><li>Osteomalacia</li><li><a test="test" href="./000414.htm">Paget disease</a> of bone</li><li>Sarcoidosis </li></ul><p>Lower-than-normal ALP levels</p><ul><li>Hypophosphatasia</li><li>Hypothyroidism</li><li>Malnutrition</li><li>Pernicious anemia</li><li><a test="test" href="./002467.htm">Protein</a> deficiency</li><li>Wilson disease</li><li>Zinc deficiency</li></ul><p>Other conditions for which the test may be done:</p><ul><li><a test="test" href="./000281.htm">Alcoholic liver disease (hepatitis/cirrhosis)</a></li><li><a test="test" href="./000944.htm">Alcohol use disorder</a></li><li><a test="test" href="./000220.htm">Biliary stricture</a></li><li>Gallstones</li><li><a test="test" href="./000448.htm">Giant cell (temporal, cranial) arteritis</a></li><li><a test="test" href="./000399.htm">Multiple endocrine neoplasia (MEN) II</a></li><li>Pancreatitis</li><li><a test="test" href="./000516.htm">Renal cell carcinoma</a></li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Alkaline phosphatase</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Images</h2></div><div class="section-button"><button type="submit" aria-controls="section-tnails" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/10026t.jpg" alt="Blood test" title="Blood test" class="side-img"/><a href="../imagepages/10026.htm">Blood test</a></li>
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</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
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</div></div><div class="section-body" id="section-Ref"><p>Fogel EL, Sherman S. Diseases of the gallbladder and bile ducts. In: Goldman L, Schafer AI, eds. <em>Goldman-Cecil Medicin</em>e. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 146.</p><p>Korenblat KM, Berk PD. Approach to the patient with jaundice or abnormal liver tests. In: Goldman L, Schafer AI, eds. <em>Goldman-Cecil Medicine</em>. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 138.</p><p>Martin P. Approach to the patient with liver disease. In: Goldman L, Schafer AI, eds. <em>Goldman-Cecil Medicine</em>. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 137.</p><p>Pincus MR, Abraham NZ, Bluth M. Interpreting laboratory results. In: McPherson RA, Pincus MR, eds. <em>Henry's Clinical Diagnosis and Management by Laboratory Methods</em>. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 9.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 6/20/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Jacob Berman, MD, MPH, Clinical Assistant Professor of Medicine, Division of General Internal Medicine, University of Washington School of Medicine, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
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