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<link rel="alternative" hreflang="en" href="https://medlineplus.gov/ency/article/000113.htm"/><meta property="og:title" content="Rheumatoid lung disease: MedlinePlus Medical Encyclopedia"/><meta property="og:url" content="https://medlineplus.gov/ency/article/000113.htm"/><meta property="twitter:title" content="Rheumatoid lung disease: MedlinePlus Medical Encyclopedia"/><meta name="twitter:card" content="summary_large_image"/><meta name="description" content="Rheumatoid lung disease is a group of lung problems related to rheumatoid arthritis (RA). The condition can include:"/><meta itemprop="description" name="description" content="Rheumatoid lung disease is a group of lung problems related to rheumatoid arthritis (RA). The condition can include:"/><meta property="og:description" content="Rheumatoid lung disease is a group of lung problems related to rheumatoid arthritis (RA). The condition can include:"/><meta property="twitter:description" content="Rheumatoid lung disease is a group of lung problems related to rheumatoid arthritis (RA). The condition can include:"/><meta property="og:image" content="https://medlineplus.gov/images/share_ency_1.jpg"/><meta property="og:image" content="https://medlineplus.gov/images/share_ency_2.jpg"/><meta property="og:image" content="https://medlineplus.gov/images/share_ency_3.jpg"/><meta property="twitter:image" content="https://medlineplus.gov/images/share_ency_1.jpg"/>
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</div><div><span>Rheumatoid lung disease</span></div></div>
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<article><div id="d-article"><div class="page-info"><div class="page-title"><a name="start" id="start">
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</a><h1 class="with-also" itemprop="name">Rheumatoid lung disease</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Rheumatoid lung disease is a group of lung problems related to <a test="test" href="./000431.htm">rheumatoid arthritis</a> (RA). The condition can include:</p><ul><li>Blockage of the small airways (bronchiolitis obliterans)</li><li>Fluid in the chest (<a test="test" href="./000086.htm">pleural effusions</a>)</li><li>High blood pressure in the lungs (<a test="test" href="./000112.htm">pulmonary hypertension</a>)</li><li>Lumps in the lungs (nodules)</li><li>Scarring (<a test="test" href="./000128.htm">pulmonary fibrosis</a>)</li></ul></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>Causes</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>Lung problems are common in RA. They often cause no symptoms, but for some people they are the main symptom of their RA.</p><p>The cause of lung disease associated with RA is unknown. Sometimes, the medicines used to treat RA, especially methotrexate, may result in lung disease.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Symptoms</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Symptoms may include any of the following:</p><ul><li>Chest pain</li><li><a test="test" href="./003072.htm">Cough</a></li><li>Fever</li><li><a test="test" href="./003075.htm">Shortness of breath</a></li><li>
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Joint pain, stiffness, and swelling
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</li><li><a test="test" href="./003230.htm">Skin nodules</a></li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Exams and Tests</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>Your health care provider will perform a physical examination and ask about your symptoms.</p><p>Symptoms depend on the type of lung disease RA is causing in the lungs.</p><p>When listening to the lungs with a stethoscope, your provider may hear normal breath sounds or:</p><ul><li>Crackles (rales)</li><li>Decreased breath sounds</li><li>Wheezing</li><li>A rubbing sound</li></ul><p>When listening to the heart, there may be abnormal heart sounds.</p><p>The following tests may show signs of rheumatoid lung disease:</p><ul><li><a test="test" href="./003804.htm">Chest x-ray</a></li><li><a test="test" href="./003788.htm">CT scan of the chest</a></li><li><a test="test" href="./003869.htm">Echocardiogram</a> (may show pulmonary hypertension)</li><li>Lung biopsy (bronchoscopic, video-assisted, or <a test="test" href="./003861.htm">open</a>)</li><li><a test="test" href="./003853.htm">Lung function tests</a></li><li>Needle inserted into the fluid around the lung (<a test="test" href="./003420.htm">thoracentesis</a>)</li><li><a test="test" href="./003548.htm">Blood tests for rheumatoid arthritis</a></li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Treatment</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>Many people with this condition have no symptoms. Treatment is aimed at the health problems causing the lung problem and the complications caused by the disorder. Corticosteroids or other medicines that suppress the immune system are sometimes useful.</p><p>There is emerging evidence that pirfenidone and nintedanib may work for people with fibrosis due to rheumatoid lung disease.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Outlook (Prognosis)</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>Outcome is related to the underlying disorder and the type and severity of lung disease. In severe cases, lung transplantation can be considered. This is more common in cases of bronchiolitis obliterans, pulmonary fibrosis, or pulmonary hypertension.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Possible Complications</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>Rheumatoid lung disease may lead to:</p><ul><li>
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Collapsed lung (<a test="test" href="./000087.htm">pneumothorax</a>)</li><li>
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Pulmonary hypertension
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</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>When to Contact a Medical Professional</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>Contact your provider right away if you have rheumatoid arthritis and you develop unexplained breathing difficulties or worsening of baseline breathing difficulties.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Lung disease - rheumatoid arthritis; Rheumatoid nodules; Rheumatoid lung</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Patient Instructions</h2></div><div class="section-button"><button type="submit" aria-controls="section-carepnt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div name="Patient Instructions" class="section-body" id="section-carepnt"><ul class="side-nav"><li><a href="../patientinstructions/000016.htm">Interstitial lung disease - adults - discharge</a></li>
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</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Corte TJ, Wells AU. Connective tissue diseases. In: Broaddus VC, Ernst JD, King TE, et al, eds. <em>Murray and Nadel's Textbook of Respiratory Medicine</em>. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 92.</p><p>Ozasa M, Fuluka J, Smith ML. Chronic diffuse lung diseases. In: Smith ML, Leslie KO, Wick MR, eds. <em>Practical Pulmonary Pathology</em>. 4th ed. Philadelphia, PA: Elsevier; 2024:chap 8.</p></div></div></section>
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