1166 lines
38 KiB
HTML
1166 lines
38 KiB
HTML
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<!doctype html>
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<html lang="en">
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<head>
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<meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no">
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<meta http-equiv="X-UA-Compatible" content="IE=edge" />
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<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
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||
<meta http-equiv="X-UA-Compatible" content="IE=edge,chrome=1"/>
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<link rel="preconnect" href="https://fonts.googleapis.com">
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<link rel="preconnect" href="https://fonts.gstatic.com" crossorigin>
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<link href="https://fonts.googleapis.com/css2?family=Roboto:wght@100;300;400;500;700&display=swap" rel="stylesheet">
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<link rel="stylesheet" href="https://use.fontawesome.com/releases/v5.0.10/css/all.css" integrity="sha384-+d0P83n9kaQMCwj8F4RJB66tzIwOKmrdb46+porD/OvrJ+37WqIM7UoBtwHO6Nlg" crossorigin="anonymous">
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<link rel="schema.DC" href="http://purl.org/dc/elements/1.1/" title="The Dublin Core metadata Element Set" />
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<link rel="stylesheet" href="/home_assets/uswds/css/styles.css">
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<title>ATC Source Information</title>
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<link rel="schema.DC" href="http://purl.org/dc/elements/1.1/" title="The Dublin Core metadata Element Set" />
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<meta name="DC.Title" content="ATC Source Information" />
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<meta name="DC.Publisher" content="U.S. National Library of Medicine" />
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<meta name="DC.Date.Issued" content="2018-12-20" />
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<meta name="DC.Date.Modified" content="2024-04-10" />
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<meta name="NLMDC.Date.LastReviewed" content="2024-04-10" />
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<meta name="NLM.Contact.Email" content="nlmumlscustserv@mail.nlm.nih.gov" />
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<meta name="DC.Type" content="Statistics and Reports" />
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<meta name="DC.Rights" content="Public Domain" />
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<meta name="DC.Language" content="eng" />
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<meta name="ncbitoggler" content="indicator: 'arrow'" />
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<script type = "text/javascript" src = "/scripts/jquery-min.js" language = "javascript"></script>
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<script type = "text/javascript" src = "//www.ncbi.nlm.nih.gov/core/jig/1.14.8/js/jig.min.js" language = "javascript"></script>
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<!--[if IE]>
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<script type="text/javascript" src="/scripts/PIE.js"></script>
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<![endif]-->
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<script type= "text/javascript">
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var $ = jQuery.noConflict();
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document.querySelectorAll('a[href^="#"]').forEach(anchor => {
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anchor.addEventListener('click', function (e) {
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e.preventDefault();
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document.querySelector(this.getAttribute('href')).scrollIntoView({
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behavior: 'smooth'
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});
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});
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});
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</script>
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<style type="text/css">
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.content-footnote{
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float:left;
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width:100%;
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}
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.jig-tabs{
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border:none;
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font-size:90%;
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}
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.jig-tabs img {
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float:left;
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}
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.jig-tabs li a {
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text-decoration:none !important;
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outline:none;
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background:none;
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background: -webkit-gradient(linear, left top, left bottom, from(#78a22f), to(#e7eeeb)) !important; /* For WebKit (Safari, Google Chrome) */
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}
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.count{
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font-size:.8em;
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color:#7a7a7a;
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font-weight:bold;
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position:absolute;
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right:1%;
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display: block;
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}
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h3 a {
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text-decoration:none !important;
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outline:none;
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}
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.sourcecontainer table{
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border:1px solid black;
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}
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.content-loader tr td {
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white-space: nowrap;
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.sourcecontainer table th{
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text-align:left;
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border:1px solid black;
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}
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.sourcecontainer table td{
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text-align:left;
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/*line-height:100%;*/
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border:1px solid black;
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}
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.limbox {
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border:none;
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position:relative;
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left:2%;
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font-weight: normal;
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padding-left: 1em;
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padding-right: 1em;
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padding-top: 0.5em;
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text-align: left;
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}
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.smalllimbox {
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width: 80%;
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}
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.leftlimbox {
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float: left;
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}
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.smalllimbox .limboxcontent {
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height: auto;
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margin-bottom: 1px;
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margin-left: 0;
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margin-right: 0;
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margin-top: 0;
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max-height: none
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overflow-x: auto;
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overflow-y: auto;
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padding-bottom: 1px;
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padding-left: 4px;
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padding-right: 0;
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padding-top: 0;
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}
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.limboxcontent .ncbitoggler span, .limboxcontent span.num-sel {
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display: block;
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}
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.limboxcontent h3 {
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-moz-background-clip: border;
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-moz-background-size: auto auto;
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background-attachment: scroll;
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background-color: #EEEEEE;
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background-image: none;
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background-position: 0 0;
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background-repeat: repeat;
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border-bottom-color: #CCCCCC;
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border-bottom-style: solid;
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border-bottom-width: 1px;
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border-left-color-ltr-source: physical;
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border-left-color-rtl-source: physical;
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border-left-color-value: #CCCCCC;
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border-left-style-ltr-source: physical;
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border-left-style-rtl-source: physical;
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border-left-width-rtl-source: physical;
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border-right-color-ltr-source: physical;
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border-right-color-rtl-source: physical;
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border-right-color-value: #CCCCCC;
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border-right-style-ltr-source: physical;
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border-right-style-rtl-source: physical;
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border-right-style-value: solid;
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border-right-width-ltr-source: physical;
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border-right-width-rtl-source: physical;
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border-right-width-value: 1px;
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border-top-color: #CCCCCC;
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border-top-style: solid;
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border-top-width: 1px;
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font-size: 1em;
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margin-bottom: 0.5em;
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margin-top: 0.5em;
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position: relative;
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}
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.resourceruntime {
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font-weight: normal;
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}
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.resourceformat {
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font-weight: normal;
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}
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</style>
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<!-- Google Tag Manager --><script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push(
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{'gtm.start': new Date().getTime(),event:'gtm.js'}
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);var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='//www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-MT6MLL');</script>
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<!-- End Google Tag Manager -->
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</head>
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<body>
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<!-- Google Tag Manager -->
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<noscript><iframe src="//www.googletagmanager.com/ns.html?id=GTM-MT6MLL" height="0" width="0" style="display:none;visibility:hidden" title="googletagmanager"></iframe></noscript>
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<!-- End Google Tag Manager -->
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<!-- TOP NAV -->
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<a class="usa-skipnav" href="#main">Skip to main content</a>
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<div class="usa-banner site-banner" aria-label="Official government website">
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<div class="usa-accordion">
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<header class="usa-banner__header">
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<div class="usa-banner__inner">
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<div class="grid-col-auto"> <img class="usa-banner__header-flag" src="https://assets.nlm.nih.gov/uswds/img/us_flag_small.png" alt="U.S. flag"/> </div>
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<div class="grid-col-fill tablet:grid-col-auto">
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<p class="usa-banner__header-text"> An official website of the United States government </p>
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<p class="usa-banner__header-action" aria-hidden="true"> Here’s how you know </p>
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</div>
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<button class="usa-accordion__button usa-banner__button" aria-expanded="false" aria-controls="gov-banner"> <span class="usa-banner__button-text">Here’s how you know</span> </button>
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||
</div>
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</header>
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<div class="usa-banner__content usa-accordion__content" id="gov-banner">
|
||
<div class="grid-row grid-gap-lg">
|
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<div class="usa-banner__guidance tablet:grid-col-6"> <img class="usa-banner__icon usa-media-block__img" src="https://assets.nlm.nih.gov/uswds/img/icon-dot-gov.svg" role="img" alt="" aria-hidden="true"/>
|
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<div class="usa-media-block__body">
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||
<p> <strong> Official websites use .gov </strong> <br />
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||
A <strong>.gov</strong> website belongs to an official government
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||
organization in the United States. </p>
|
||
</div>
|
||
</div>
|
||
<div class="usa-banner__guidance tablet:grid-col-6"> <img class="usa-banner__icon usa-media-block__img" src="https://assets.nlm.nih.gov/uswds/img/icon-https.svg" role="img" alt="" aria-hidden="true"/>
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<div class="usa-media-block__body">
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<p> <strong> Secure .gov websites use HTTPS </strong> <br />
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A <strong>lock</strong> ( <span class="icon-lock">
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<svg xmlns="http://www.w3.org/2000/svg" width="52" height="64" viewBox="0 0 52 64" class="usa-banner__lock-image" role="img" aria-labelledby="banner-lock-title-default banner-lock-description-default" focusable="false">
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<title id="banner-lock-title-default">Lock</title>
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<desc id="banner-lock-description-default">A locked padlock</desc>
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<path fill="#000000" fill-rule="evenodd" d="M26 0c10.493 0 19 8.507 19 19v9h3a4 4 0 0 1 4 4v28a4 4 0 0 1-4 4H4a4 4 0 0 1-4-4V32a4 4 0 0 1 4-4h3v-9C7 8.507 15.507 0 26 0zm0 8c-5.979 0-10.843 4.77-10.996 10.712L15 19v9h22v-9c0-6.075-4.925-11-11-11z"/>
|
||
</svg>
|
||
</span> ) or <strong>https://</strong> means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites. </p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<!-- HEADER -->
|
||
<header id="siteheader" class="usa-header usa-header--basic">
|
||
<div class="usa-nav-container tablet:padding-x-4 mobile-lg:padding-x-2 padding-y-1">
|
||
<div class="grid-row padding-y-105">
|
||
<div class="grid-col-8 desktop:grid-col-4 tablet-lg:grid-col-4 tablet:grid-col-6"> <a href="https://www.nlm.nih.gov/"> <img src="https://assets.nlm.nih.gov/uswds/img/NLM_White.png" alt="NLM logo" class="logo margin-top-1"> </a> </div>
|
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<div class="desktop:grid-col-4 desktop:grid-offset-4 tablet-lg:grid-col-6 tablet-lg:grid-offset-2 tablet:grid-col-6 grid-col-12">
|
||
<form class="usa-search desktop:margin-top-2 tablet:margin-top-2 mobile:margin-top-1" role="search" data-gtm-form-interact-id="0" method="get" action="//vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta" target="_self" name="searchForm" id="searchForm2">
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<input class="usa-input ui-autocomplete-input" aria-label="Search" type="search" name="query" data-gtm-form-interact-field-id="0" id="search2" autocomplete="off" placeholder="Search NLM" >
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<input type="hidden" name="v:project" value="nlm-main-website">
|
||
<button class="usa-button border border-top border-bottom border-right border-white" role="button" aria-label="Search" type="submit"> <span class="usa-search__submit-text"> <i class="fas fa-search"></i> </span> </button>
|
||
</form>
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</div>
|
||
</div>
|
||
</div>
|
||
</header>
|
||
<div class="bg-secondary insertCOOP">
|
||
<div class="usa-nav-container">
|
||
<div class="usa-navbar ">
|
||
<button class="usa-menu-btn">Menu</button>
|
||
</div>
|
||
<nav aria-label="Primary navigation" class="usa-nav">
|
||
<button class="usa-nav__close"><img src="https://assets.nlm.nih.gov/uswds/img/close.svg" alt="close"></button>
|
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<ul class="usa-nav__primary usa-accordion insertNav">
|
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|
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<li class="usa-nav__primary-item desktop-lg:margin-x-5 desktop:margin-x-3 tablet:margin-x-0">
|
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<button type="button" class="usa-accordion__button usa-nav__link usa-current" aria-expanded="false" aria-controls="basic-nav-section-one"> <span>Products and Services <i class="fas fa-caret-down margin-left-05"></i> </span> </button>
|
||
<ul id="basic-nav-section-one" class="usa-nav__submenu bg-secondary" hidden="">
|
||
<li class="usa-nav__submenu-item"> <a href="//eresources.nlm.nih.gov/nlm_eresources/"><span>All Products and Services</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="//clinicaltrials.gov/"><span>ClinicalTrials.gov</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="//collections.nlm.nih.gov/"><span>Digital Collections</span></a> </li>
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<li class="usa-nav__submenu-item"> <a href="//catalog.nlm.nih.gov"><span>LocatorPlus Catalog</span></a> </li>
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||
<li class="usa-nav__submenu-item"> <a href="//meshb.nlm.nih.gov/search"><span>Medical Subject Headings (MeSH)</span></a> </li>
|
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<li class="usa-nav__submenu-item"> <a href="//medlineplus.gov/"><span>MedlinePlus</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="//pubmed.ncbi.nlm.nih.gov/"><span>PubMed/MEDLINE</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="//uts.nlm.nih.gov/uts/"><span>Unified Medical Language System (UMLS)</span></a> </li>
|
||
</ul>
|
||
</li>
|
||
<li class="usa-nav__primary-item desktop-lg:margin-x-5 desktop:margin-x-3 tablet:margin-x-0">
|
||
<button type="button" class="usa-accordion__button usa-nav__link usa-current" aria-expanded="false" aria-controls="basic-nav-section-two"> <span> Resources for You <i class="fas fa-caret-down margin-left-05"></i></span> </button>
|
||
<ul id="basic-nav-section-two" class="usa-nav__submenu bg-secondary" hidden="">
|
||
<li class="usa-nav__submenu-item"> <a href="/portals/researchers.html"><span>For Researchers</span></a> </li>
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||
<li class="usa-nav__submenu-item"> <a href="/portals/publishers.html "><span>For Publishers</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/portals/librarians.html"><span>For Librarians</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/training.html "><span>For Educators/Trainers </span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/portals/healthcare.html"><span>For Health care Professionals</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/portals/public.html "><span>For the Public</span></a> </li>
|
||
</ul>
|
||
</li>
|
||
<li class="usa-nav__primary-item desktop-lg:margin-x-5 desktop:margin-x-3 tablet:margin-x-0">
|
||
<button type="button" class="usa-accordion__button usa-nav__link usa-current" aria-expanded="false" aria-controls="basic-nav-section-three"> <span>Explore NLM <i class="fas fa-caret-down margin-left-05"></i> </span> </button>
|
||
<ul id="basic-nav-section-three" class="usa-nav__submenu bg-secondary" hidden="">
|
||
<li class="usa-nav__submenu-item"> <a href="/about/index.html"><span>About the Library</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/about/visitor.html"><span>Visit the Library</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/hmd/index.html"><span>History of Medicine</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/about/org.html"><span>NLM by Organization</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/news/newsandevents.html"><span>News, Events, and Updates</span></a> </li>
|
||
</ul>
|
||
</li>
|
||
<li class="usa-nav__primary-item desktop-lg:margin-x-5 desktop:margin-x-3 tablet:margin-x-0">
|
||
<button type="button" class="usa-accordion__button usa-nav__link usa-current" aria-expanded="false" aria-controls="basic-nav-section-four"> <span> Grants and Research <i class="fas fa-caret-down margin-left-05"></i> </span> </button>
|
||
<ul id="basic-nav-section-four" class="usa-nav__submenu bg-secondary" hidden="">
|
||
<li class="usa-nav__submenu-item"> <a href="/ep/index.html"><span>NLM Extramural Programs</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="/research/index.html"><span>NLM Intramural Research Program</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="https://www.ncbi.nlm.nih.gov/"><span>National Center for Biotechnology Information</span></a> </li>
|
||
<li class="usa-nav__submenu-item"> <a href="//lhncbc.nlm.nih.gov/"><span>Lister Hill National Center for Biomedical Communications</span></a> </li>
|
||
</ul>
|
||
</li>
|
||
|
||
</ul>
|
||
</nav>
|
||
</div>
|
||
</div>
|
||
|
||
<!-- End of TOP NAV -->
|
||
|
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|
||
|
||
|
||
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||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<!-- DIVISIONAL BANNER -->
|
||
|
||
<div class="bg-gray-70">
|
||
<div class="grid-container">
|
||
<div class="grid-row divisional">
|
||
|
||
|
||
|
||
|
||
<div class="grid-col text-white">
|
||
|
||
<div class="float-left">
|
||
<h4 class="margin-bottom-0">Unified Medical Language System<small><sup>®</sup></small> (UMLS<small><sup>®</sup></small>)</h4>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
<div class="float-right margin-top-05">
|
||
<p>
|
||
|
||
|
||
|
||
<a class="text-white" href="/research/umls/faq_main.html">FAQ</a>
|
||
|
||
|
||
|
||
| <a class="text-white" href="/research/umls/support.html">Customer Support</a>
|
||
|
||
|
||
|
||
|
||
</p>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<!--END DIVISIONAL BANNER -->
|
||
|
||
<!-- Breadcrumbs -->
|
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<div class="grid-container">
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<nav class="usa-breadcrumb usa-breadcrumb--wrap padding-top-1" aria-label="Breadcrumbs">
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<ol class="usa-breadcrumb__list">
|
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<li class="usa-breadcrumb__list-item"> <a href="/index.html" class="usa-breadcrumb__link"><span>Home</span></a> </li>
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<li class="usa-breadcrumb__list-item"> <a href="/healthit" class="usa-breadcrumb__link"><span>Health IT</span></a> </li>
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|
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<li class="usa-breadcrumb__list-item"> <a href="/research/umls/index.html" class="usa-breadcrumb__link"><span>UMLS home page</span></a> </li>
|
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||
|
||
|
||
|
||
<li class="usa-breadcrumb__list-item"> <a href="/research/umls/rxnorm/index.html" class="usa-breadcrumb__link"><span>RxNorm</span></a> </li>
|
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|
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|
||
|
||
</ol>
|
||
</nav>
|
||
</div>
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||
<!-- End Breadcrumbs -->
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|
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<main class="padding-bottom-5" id="main">
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<div class="grid-container">
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<div class="grid-row">
|
||
|
||
<div class="grid-col">
|
||
|
||
|
||
|
||
<div class="h1">ATC Source Information</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div id="source-doc-wrapper">
|
||
<div id="source-doc-intro">
|
||
<p> </p>
|
||
<p>Click on a topic below the Source Synopsis section to display details.</p>
|
||
</div>
|
||
|
||
|
||
<h2>Source Synopsis</h2>
|
||
|
||
<p><strong>Web site:</strong><br />
|
||
<a href="https://www.whocc.no/atc/structure_and_principles/" target = "_blank">https://www.whocc.no/atc/structure_and_principles/</a></p>
|
||
<p><strong>Authority</strong><br />
|
||
The World Health Organization Collaborating Center for Drug Statistics Methodology produces and maintains the Anatomical Therapeutic Chemical Classification System with Defined Daily Doses (ATC/DDD).</p>
|
||
<p> The RxNorm includes ATC information only.</p>
|
||
<p><strong>Purpose</strong><br />
|
||
ATC classifies therapeutic drugs to enable drug research and to improve the quality of drug use.</p>
|
||
<p><strong>Description</strong><br />
|
||
ATC classifies drugs at five different levels. Each level is a different grouping of drugs. Groupings of active substances include the organ or system on which the drug acts as well as therapeutic, pharmacological, and chemical properties of the drug.</p>
|
||
<p><strong>RxNorm Scope</strong><br>
|
||
The RxNorm representation of ATC includes ingredients and drug classes.</p>
|
||
<!--<p><strong>Audience</strong><br />
|
||
xx
|
||
</p> -->
|
||
<p><strong>Update Frequency</strong><br />
|
||
ATC is updated annually. </p>
|
||
|
||
<p><strong>RxNorm Update Frequency</strong><br />
|
||
ATC is updated annually in RxNorm, typically in the February RxNorm monthly release.</p>
|
||
<p><strong>Sites Consulted</strong></p>
|
||
<ol>
|
||
<li>WHOCC - Home [Internet]. Oslo: WHO Collaborating Centre for Drug Statistics Methodology [updated 2018 Feb 15]. ATC/DDD methodology - History. WHOCC; c2018 [cited 2020 Oct 12]. Available from: <a href="https://www.whocc.no/atc_ddd_methodology/history/" target = "_blank"> https://www.whocc.no/atc_ddd_methodology/history/</a>.</li>
|
||
|
||
<li>WHOCC - Home [Internet]. Oslo: WHO Collaborating Centre for Drug Statistics Methodology [updated 2018 Nov 26]. ATC - Structure and Principles; [updated 2018 Feb 15; cited 2018 Dec 7]. Available from: <a href="https://www.whocc.no/atc/structure_and_principles/" target = "_blank">https://www.whocc.no/atc/structure_and_principles/</a>. </li></ol>
|
||
|
||
<div class="limboxcontent">
|
||
<h3><a class="jig-ncbitoggler">Metadata</a></h3>
|
||
<div class="sourcecontainer">
|
||
<table>
|
||
<tr>
|
||
<th>Field</th>
|
||
<th>Value</th>
|
||
</tr>
|
||
<!--<tr><td>Versioned Source Abbreviation</td><td>ATC_2019</td></tr>
|
||
<tr><td>Source Official Name</td><td>Anatomical Therapeutic Chemical Classification System</td></tr>
|
||
-->
|
||
<tr><td>Short Name</td><td>Anatomical Therapeutic Chemical Classification System</td></tr>
|
||
<tr><td>Family</td><td>ATC</td></tr>
|
||
<tr><td>Source Restriction Level</td><td>0</td></tr>
|
||
<tr><td>Language</td><td>ENG</td></tr>
|
||
<tr><td>License Contact</td><td>WHO Collaborating Centre for Drug Statistics Methodology<br />Norwegian Institute of Public Health<br />P.O.Box 4404 Nydalen<br />Oslo<br />Norway<br />0403<br />+47 21 07 81 60<br />+47 21 07 81 46<br />whocc@fhi.no<br />http://www.whocc.no/copyright_disclaimer/</td></tr>
|
||
<tr><td>Content Contact</td><td>WHO Collaborating Centre for Drug Statistics Methodology<br />Norwegian Institute of Public Health<br />P.O.Box 4404 Nydalen<br />Oslo<br />Norway<br />0403<br />+47 21 07 81 60<br />+47 21 07 81 46<br />whocc@fhi.no<br />http://www.whocc.no/</td></tr>
|
||
<!--<tr><td>Citation</td><td>WHO Collaborating Centre for Drug Statistics Methodology<br />Anatomical Therapeutic Chemical (ATC) classification system<br />2019<br />Oslo, Norway<br />WHO Collaborating Centre for Drug Statistics Methodology<br />http://www.whocc.no/copyright_disclaimer/<br /></td></tr>
|
||
-->
|
||
</table>
|
||
<br>
|
||
</div>
|
||
|
||
<h3><a class="jig-ncbitoggler">Source Representation</a></h3>
|
||
<div class="sourcecontainer">
|
||
<p>This section lists specific source data elements and provides information on their representation in RxNorm.</p>
|
||
<p>
|
||
<strong>Summary of Changes</strong>
|
||
</p>
|
||
<p>There are no changes to the original data format or to RxNorm source processing.</p>
|
||
<p>
|
||
<strong>Source Provided Files:</strong>
|
||
</p>
|
||
<p>The ATC file is available from: </p>
|
||
<p>
|
||
<a href="https://www.whocc.no/atc_ddd_index_and_guidelines/atc_ddd_index/">https://www.whocc.no/atc_ddd_index_and_guidelines/atc_ddd_index/</a>
|
||
</p>
|
||
<p>The following file is used for RxNorm source processing.</p>
|
||
<table class="wrapped">
|
||
<tbody class="">
|
||
<tr class="">
|
||
<td>
|
||
<p>
|
||
<strong>File Name</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>Description</strong>
|
||
</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p><YYYY> ATC Index with</p>
|
||
<p> DDDs_electronic version.xlsx</p>
|
||
</td>
|
||
<td>
|
||
<p>Excel file containing information on codes and levels</p>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<br/>
|
||
<strong>Source-Provided Files: Details</strong>
|
||
|
||
<p>The following is a list of fields in the ATC source files used in RxNorm processing and their representations in RxNorm.</p>
|
||
<p>Consult the ATC web site for additional ATC information at: <a href="https://www.whocc.no/atc/structure_and_principles/">https://www.whocc.no/atc/structure_and_principles/</a>
|
||
</p>
|
||
<p>File name: 2023 ATC Index with DDDs_electronic version.xlsx; only the first tab, “ATCIndeks with DDDs 2023” is processed</p>
|
||
<br/>
|
||
<table class="wrapped">
|
||
<tbody class="">
|
||
<tr class="">
|
||
<td>
|
||
<p>
|
||
<strong>#</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>ATC Field Name</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>Description</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>RxNorm Representation</strong>
|
||
</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>1</p>
|
||
</td>
|
||
<td>
|
||
<p>ATC Code</p>
|
||
</td>
|
||
<td>
|
||
<p>1-7 character alphanumeric code for the ATC name</p>
|
||
</td>
|
||
<td>
|
||
<p>RXNCONSO.CODE</p>
|
||
<p>
|
||
<br/>
|
||
</p>
|
||
<p>RXNSAT.ATN = ATC_LEVEL</p>
|
||
<p>Levels are implied by the number of characters in the ATC code:</p>
|
||
<p>1 character: Level 1</p>
|
||
<p>3 characters: Level 2</p>
|
||
<p>4 characters: Level 3</p>
|
||
<p>5 characters: Level 4</p>
|
||
<p>7 characters: Level 5</p>
|
||
<p>
|
||
<br/>
|
||
</p>
|
||
<p>RXNREL.RRF</p>
|
||
<p>Used to derive hierarchical relationships:</p>
|
||
<p>Levels 1-4:</p>
|
||
<p>REL = PAR/CHD</p>
|
||
<p>RELA = inverse_isa/isa</p>
|
||
<p>Level 5: </p>
|
||
<p>REL = PAR/CHD</p>
|
||
<p>RELA = has_member/member_of</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>2</p>
|
||
</td>
|
||
<td>
|
||
<p>ATC level name</p>
|
||
</td>
|
||
<td>
|
||
<p>ATC substance name</p>
|
||
<p>In the ATC classification system, the active substances are classified in a hierarchy with five different levels. The system has fourteen main anatomical/pharmacological groups or 1st levels. Each ATC main group is divided into 2nd levels which could be either pharmacological or therapeutic groups. The 3rd and 4th levels are chemical, pharmacological or therapeutic subgroups and the 5th level is the chemical substance. The 2nd, 3rd and 4th levels are often used to identify pharmacological subgroups when that is considered more appropriate than therapeutic or chemical subgroups.</p>
|
||
</td>
|
||
<td>
|
||
<p>RXNCONSO.STR</p>
|
||
<p>TTY = PT for levels 1-4</p>
|
||
<p>TTY = IN for level 5</p>
|
||
<p>
|
||
<br/>
|
||
</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>3</p>
|
||
</td>
|
||
<td>
|
||
<p>DDD</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>4</p>
|
||
</td>
|
||
<td>
|
||
<p>Unit</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>5</p>
|
||
</td>
|
||
<td>
|
||
<p>Adm.R</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>6</p>
|
||
</td>
|
||
<td>
|
||
<p>Comment</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<br/>
|
||
</div>
|
||
|
||
<h3><a class="jig-ncbitoggler">RxNorm Representation</a></h3>
|
||
<div class="sourcecontainer">
|
||
<p>This section lists RxNorm data elements and traces them back to the specific ATC data that populates them.</p>
|
||
<p>
|
||
<strong>Summary of Changes</strong>
|
||
</p>
|
||
<p>There are no changes to the original data format or to RxNorm source processing.</p>
|
||
<p>Source Provided Files:</p>
|
||
<p>The ATC file is available from: </p>
|
||
<p>
|
||
<a href="https://www.whocc.no/atc_ddd_index_and_guidelines/atc_ddd_index/">https://www.whocc.no/atc_ddd_index_and_guidelines/atc_ddd_index/</a>
|
||
</p>
|
||
<p>The following file is used for RxNorm source processing.</p>
|
||
<table class="wrapped">
|
||
<tbody class="">
|
||
<tr class="">
|
||
<td>
|
||
<p>
|
||
<strong>File Name</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>Description</strong>
|
||
</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>2023 ATC Index with</p>
|
||
<p> DDDs_electronic version.xlsx</p>
|
||
</td>
|
||
<td>
|
||
<p>Excel file containing information on codes and levels</p>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
|
||
<br/>
|
||
|
||
<p>RxNorm Identifiers:</p>
|
||
<p>Identifiers are assigned as follows:</p>
|
||
<table class="wrapped">
|
||
<tbody class="">
|
||
<tr class="">
|
||
<td>
|
||
<p>
|
||
<strong>Identifier</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>Origin</strong>
|
||
</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>CODE</p>
|
||
</td>
|
||
<td>
|
||
<p>ATC code</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>SAUI</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>SCUI</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>SDUI</p>
|
||
</td>
|
||
<td>
|
||
<p>Not applicable</p>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<br/>
|
||
|
||
<p>Atoms (RXNCONSO):</p>
|
||
<table class="wrapped">
|
||
<tbody class="">
|
||
<tr class="">
|
||
<td>
|
||
<p>
|
||
<strong>Term Type</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>Origin</strong>
|
||
</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>IN</p>
|
||
</td>
|
||
<td>
|
||
<p>ATC level name for Level 5 codes</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>PT</p>
|
||
</td>
|
||
<td>
|
||
<p>ATC level name for Level 1-4 codes</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>RXN_IN</p>
|
||
</td>
|
||
<td>
|
||
<p>Created by RxNorm editors for disambiguation purposes, based on the hierarchy</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>RXN_PT</p>
|
||
</td>
|
||
<td>
|
||
<p>Created by RxNorm editors for disambiguation purposes, based on the hierarchy</p>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<br/>
|
||
<p>Relationships (RXNREL):</p>
|
||
<table class="wrapped">
|
||
<tbody class="">
|
||
<tr class="">
|
||
<td>
|
||
<p>
|
||
<strong>REL/inverse REL</strong>
|
||
</p>
|
||
<p>
|
||
<strong>RELA/inverse RELA</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>Origin</strong>
|
||
</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>PAR/CHD</p>
|
||
<p>has_member/member_of</p>
|
||
</td>
|
||
<td>
|
||
<p>Hierarchical relationship connecting Level 5 (chemical substance) to Level 4 subgroup (IN to PT)</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>PAR/CHD</p>
|
||
<p>inverse_isa/isa</p>
|
||
</td>
|
||
<td>
|
||
<p>Hierarchical relationships connecting Levels 1-4 (PT to PT)</p>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<br/>
|
||
|
||
<p>Attributes (RXNSAT):</p>
|
||
<table class="wrapped">
|
||
<tbody class="">
|
||
<tr class="">
|
||
<td>
|
||
<p>
|
||
<strong>ATN</strong>
|
||
</p>
|
||
</td>
|
||
<td>
|
||
<p>
|
||
<strong>Origin</strong>
|
||
</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>ATC_LEVEL</p>
|
||
</td>
|
||
<td>
|
||
<p>Derived from ATC code:</p>
|
||
<p>
|
||
<br/>
|
||
</p>
|
||
<p>1: main anatomical/pharmacological groups</p>
|
||
<p>2. Either pharmacological or therapeutic groups </p>
|
||
<p>3,4: Chemical, pharmacological or therapeutic subgroups</p>
|
||
<p>5: Chemical substance</p>
|
||
</td>
|
||
</tr>
|
||
<tr class="">
|
||
<td>
|
||
<p>IS_DRUG_CLASS</p>
|
||
</td>
|
||
<td>
|
||
<p>“Y” for PT (level 1-4) codes</p>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
<h3><a class="jig-ncbitoggler">Data Examples with Sample Database Queries</a></h3>
|
||
<div class="sourcecontainer">
|
||
<p>This section lists source terminology specific data examples and sample database queries using Structured Query Language (SQL) to obtain the data. For more information about RxNorm data and files, see the <a href="https://www.nlm.nih.gov/research/umls/rxnorm/docs/index.html" target="_blank">RxNorm Technical Documentation</a>.</p>
|
||
|
||
|
||
<h4>Names and Codes in RXNCONSO.RRF</h4>
|
||
<p>Here are sample source terminology code, source string, RxNorm Concept Unique Identifier (RXCUI), RxNorm string, RxNorm term type (TTY), and suppress values.</p>
|
||
<table>
|
||
<tbody>
|
||
<tr>
|
||
<th>SOURCE_CODE</th>
|
||
<th>SOURCE_STR</th>
|
||
<th>RXCUI</th>
|
||
<th>RXNORM_STR</th>
|
||
<th>RXNORM_TTY</th>
|
||
<th>SUPPRESS</th>
|
||
</tr>
|
||
<tr>
|
||
<td>C01EB16</td>
|
||
<td>ibuprofen</td>
|
||
<td>5640</td>
|
||
<td>Ibuprofen</td>
|
||
<td>IN</td>
|
||
<td>N</td>
|
||
</tr>
|
||
<tr>
|
||
<td>G02CC01</td>
|
||
<td>ibuprofen</td>
|
||
<td>5640</td>
|
||
<td>Ibuprofen</td>
|
||
<td>IN</td>
|
||
<td>N</td>
|
||
</tr>
|
||
<tr>
|
||
<td>M02AA13</td>
|
||
<td>ibuprofen</td>
|
||
<td>5640</td>
|
||
<td>Ibuprofen</td>
|
||
<td>IN</td>
|
||
<td>N</td>
|
||
</tr>
|
||
<tr>
|
||
<td>M01AE01</td>
|
||
<td>ibuprofen</td>
|
||
<td>5640</td>
|
||
<td>Ibuprofen</td>
|
||
<td>IN</td>
|
||
<td>N</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
|
||
<br/>
|
||
<p>Here is a sample database query to retrieve the data above:</p>
|
||
|
||
<p>SELECT distinct rc1.code as source_code, rc1.str as source_str, rc1.rxcui, rc2.str as rxnorm_str, rc2.tty as rxnorm_tty, rc2.suppress<br />
|
||
FROM rxnconso rc1, rxnconso rc2<br />
|
||
WHERE rc1.code in ('C01EB16', 'G02CC01', 'M01AE01', 'M02AA13')<br />
|
||
AND rc1.sab = 'ATC'<br />
|
||
AND rc1.rxcui = rc2.rxcui<br />
|
||
AND rc2.sab = 'RXNORM';</p>
|
||
|
||
<h4>Names and Relationships in RXNCONSO.RRF and RXNREL.RRF </h4>
|
||
<p>Here are sample source terminology code, source string, RXCUI, relationship name, RxNorm term type (TTY), brand name, and suppress values.</p>
|
||
<table>
|
||
<tbody>
|
||
<tr>
|
||
<th>SOURCE_CODE</th>
|
||
<th>SOURCE_STR</th>
|
||
<th>RXCUI</th>
|
||
<th>RELA</th>
|
||
<th>RXNORM_TTY</th>
|
||
<th>BN</th>
|
||
<th>SUPPRESS</th>
|
||
</tr>
|
||
<tr>
|
||
<td>C01EB16</td>
|
||
<td>ibuprofen</td>
|
||
<td>5640</td>
|
||
<td>has_tradename</td>
|
||
<td>BN</td>
|
||
<td>Advil</td>
|
||
<td>N</td>
|
||
</tr>
|
||
<tr>
|
||
<td>C01EB16</td>
|
||
<td>ibuprofen</td>
|
||
<td>5640</td>
|
||
<td>has_tradename</td>
|
||
<td>BN</td>
|
||
<td>Brufen</td>
|
||
<td>N</td>
|
||
</tr>
|
||
<tr>
|
||
<td>C01EB16</td>
|
||
<td>ibuprofen</td>
|
||
<td>5640</td>
|
||
<td>has_tradename</td>
|
||
<td>BN</td>
|
||
<td>Motrin</td>
|
||
<td>N</td>
|
||
</tr>
|
||
<tr>
|
||
<td>C01EB16</td>
|
||
<td>ibuprofen</td>
|
||
<td>5640</td>
|
||
<td>has_tradename</td>
|
||
<td>BN</td>
|
||
<td>Nuprin</td>
|
||
<td>N</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
|
||
<br/>
|
||
<p>Here is a sample database query to retrieve the data above:</p>
|
||
|
||
<p>SELECT distinct rc1.code as source_code, rc1.str as source_str, rc1.rxcui, rr.rela, rc2.tty as rxnorm_tty, rc2.str as bn, rc2.suppress<br />
|
||
FROM rxnconso rc1, rxnrel rr, rxnconso rc2<br />
|
||
WHERE rc1.code = 'C01EB16'<br />
|
||
AND rc1.sab = 'ATC'<br />
|
||
AND rc1.rxcui = rr.rxcui2<br />
|
||
AND rr.rela = 'has_tradename'<br />
|
||
AND rr.rxcui1 = rc2.rxcui<br />
|
||
AND rc2.sab = 'RXNORM'<br />
|
||
AND rc2.tty = 'BN'<br />
|
||
ORDER BY suppress;</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
<p class=”margin-top-5”><small>Last Reviewed: April 10, 2024</small></p>
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