1293 lines
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<div><div>The National Institute on Alcohol Abuse and Alcoholism Data Archive (NIAAA<sub>DA</sub>) is a data repository that houses and shares human subjects data generated by NIAAA-funded research. </div>
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<h2><strong>Overview</strong></h2>
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<div>Widespread data sharing by research communities <a href="https://grants.nih.gov/grants/guide/notice-files/NOT-AA-17-005.html">adds significant value to research and accelerates the pace of discovery</a>. NIAAA has a data-sharing initiative to create a data repository of NIAAA-funded studies that include human subjects. This repository is called the NIAAA Data Archive (NIAAA<sub>DA</sub>). NIAAA-funded investigators conducting applicable human subjects research are expected to submit de-identified, individual-level data to this data archive. Non-NIAAA funded investigators with alcohol-related data are welcome to deposit their data to the NIAAA<sub>DA</sub>. The data in the NIAAA<sub>DA</sub> are catalogued and made available to the general research community at the time of an associated publication or end of the award/support period, whichever comes first. </div>
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<div>The NIAAA<sub>DA</sub> website – <a href="https://nda.nih.gov/niaaa">https://nda.nih.gov/niaaa</a> - is the portal for all information about NIAAA-related data submissions and data access. This website serves as a resource for investigators on NIAAA-funded projects preparing to share their data through NIAAA<sub>DA</sub>. It also provides useful information for those who are thinking of applying for a grant that will have associated data sharing expectations. <strong>Grant applicants are strongly encouraged to review this website prior to submitting a human-subjects grant application to NIAAA.</strong> Anyone preparing to share data can visit this site and learn about the initial steps and pre-requisites prior to and immediately after award, understand the process to harmonize data to a common definition and deposit it in the NIAAA<sub>DA</sub>, and learn how to get help if a problem arises. Data submitted to NIAAA<sub>DA</sub> will be accessible by the general research community via NIAAA<sub>DA</sub>. </div>
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<h2><strong>Expectations for NIAAA Grant Applicants</strong></h2>
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<p>Applications submitted to or assigned to NIAAA on or after January 25, 2023 must follow the Final NIH Policy for Data Management and Sharing (<a href="https://grants.nih.gov/grants/guide/notice-files/NOT-OD-21-013.html">NOT-OD-21-013</a>) and provide a Data Management and Sharing (DMS) Plan. Per <a href="https://grants.nih.gov/grants/guide/notice-files/NOT-AA-23-002.html">NOA-AA-23-002</a>, for grants involving human subject data, NIAAA expects the data to be submitted to the NIAAA<sub>DA</sub>.</p>
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<h2><strong>NIAAA<sub>DA</sub> and the NIMH Data Archive</strong></h2>
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<div>The NIAAA<sub>DA </sub>is housed within the larger National Institute of Mental Health (NIMH) Data Archive (NDA), a data repository for human subject research. NDA is comprised of a harmonization and sharing infrastructure that supports not only the human subjects research funded by NIMH (located in the NDA itself), but also a number of repositories, including NIAAA<sub>DA</sub>, the Adolescent Brain Cognitive Development (ABCD) Data Repository, the Osteoarthritis Initiative (OAI), the Connectome Coordination Facility (CCF), the Accelerating Medicines Partnership - Schizophrenia (AMP SCZ), and the Helping to End Addition Long-Term Initiative (HEAL).</div>
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<div> </div>
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<div>NDA currently houses data on over 500,000 research subjects. The benefits of merging data from hundreds of NIH-funded research projects include:</div>
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<ul>
|
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<li><u>Secondary Data Analysis</u>: aggregate deidentified, subject-level data from multiple studies or re-analyze data from publications or findings.</li>
|
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<li><u>Experimental Design</u>: review and use existing data collection plans for new studies; analyze shared data to generate preliminary data for new grants.</li>
|
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<li><u>Rigor and Reproducibility</u>
|
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<ul>
|
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<li>Validate newly collected data prior to submission and discover and resolve harmonization issues early in the research lifecycle.</li>
|
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<li>Precisely define all data, cohorts, and analyses reported in a publication so other researchers can accurately reproduce results and design new studies for broader impacts.</li>
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<li><u>Computational Infrastructure</u>: utilize NDA’s secure web services and secure cloud infrastructure for data validation, file management, search, query, analysis, and pipeline integration.</li>
|
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|
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<div>For technical assistance with data submission please contact: </div>
|
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<p><a href="mailto:NDAhelp@mail.nih.gov">NDAhelp@mail.nih.gov</a></p>
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<div>For other inquiries please contact:</div>
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<div>The NIAAA Data Archive Team</div>
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<div><a href="mailto:niaaadataarchivehelp@mail.nih.gov">niaaadataarchivehelp@mail.nih.gov</a></div>
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