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</div><div><span>Lung diffusion testing</span></div></div>
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<article><div id="d-article"><div class="page-info"><div class="page-title"><a name="start" id="start">
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</a><h1 class="with-also" itemprop="name">Lung diffusion testing</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Lung diffusion testing measures how well the lungs exchange gases. This is an important part of <a test="test" href="./003853.htm">lung testing</a>, because the major function of the lungs is to allow oxygen to diffuse or pass into the blood from the lungs, and to allow carbon dioxide to diffuse from the blood into the lungs.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>You breathe in (inhale) air containing a very small amount of <a test="test" href="./002804.htm">carbon monoxide</a> and a tracer gas, such as methane or helium. You hold your breath for 10 seconds, then rapidly blow it out (exhale). The exhaled gas is tested to determine how much of the tracer gas was absorbed during the breath.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How to Prepare for the Test</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
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</div></div><div class="section-body" id="section-2"><p>Before taking this test:</p><ul><li>Do not eat a heavy meal before the test.</li><li>Do not smoke for at least 4 to 6 hours before the test.</li><li>If you use a bronchodilator or other inhaled medicines, ask your health care provider whether or not you can use them before the test. </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test will Feel</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>The mouthpiece fits tightly around your mouth. Clips are put on your nose. </p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Why the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>The test is used to diagnose certain lung diseases, and to monitor the status of people with established lung disease. Repeatedly measuring the diffusing capacity can help determine whether the disease is improving or getting worse.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Normal Results</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>Normal test results depend on a person's:</p><ul><li>
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Age
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</li><li>
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Sex
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</li><li>
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Height
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</li><li>Hemoglobin (the protein in red blood cells that carries oxygen) level</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>What Abnormal Results Mean</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>Abnormal results mean that gases do not move normally across the lung tissues into the blood vessels of the lung. This may be due to lung diseases such as:</p><ul><li><a test="test" href="./000091.htm">COPD</a></li><li><a test="test" href="./000128.htm">Interstitial fibrosis</a></li><li><a test="test" href="./000132.htm">Pulmonary embolism</a></li><li><a test="test" href="./000112.htm">Pulmonary hypertension</a></li><li><a test="test" href="./000076.htm">Sarcoidosis</a></li><li>Bleeding in the lung</li><li><a test="test" href="./000141.htm">Asthma</a></li><li>Reduced lung volume (capacity)</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Risks</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>There are no significant risks.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Considerations</h2></div><div class="section-button"><button type="submit" aria-controls="section-8" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-8"><p>Other <a test="test" href="./003853.htm">pulmonary function tests</a> may be done together with this test.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Diffusing capacity; DLCO test</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Images</h2></div><div class="section-button"><button type="submit" aria-controls="section-tnails" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div name="Images" class="section-body" id="section-tnails"><ul class="img-grid group">
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/9598t.jpg" alt="Lung diffusion testing" title="Lung diffusion testing" class="side-img"/><a href="../imagepages/9598.htm">Lung diffusion testing</a></li>
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</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
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</div></div><div class="section-body" id="section-Ref"><p>Bhakta NR, Kaminsky DA. Pulmonary function testing: Physiologic and technical principles. In: Broaddus VC, Ernst JD, King TE, et al, eds. <em>Murray and Nadel's Textbook of Respiratory Medicine.</em> 7th ed. Philadelphia, PA: Elsevier; 2022:chap 31.</p><p>Scanlon PD, Niven AS. Respiratory testing and function. In: Goldman L, Cooney KA, eds. <em>Goldman-Cecil Medicine</em>. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 73.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 11/25/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Denis Hadjiliadis, MD, MHS, Paul F. Harron Jr. Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
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