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</div><div><span>Gastric tissue biopsy and culture</span></div></div>
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<article><div id="d-article"><div class="page-info"><div class="page-title"><a name="start" id="start">
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</a><h1 class="with-also" itemprop="name">Gastric tissue biopsy and culture</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Gastric tissue <a test="test" href="./003416.htm">biopsy</a> is the removal of stomach tissue for examination. A culture is a laboratory test that examines the tissue sample for bacteria and other organisms that can cause disease.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>The tissue sample is removed during a procedure called <a test="test" href="./003888.htm">upper endoscopy (or EGD)</a>. It is done with a flexible tube with a small camera (flexible endoscope) at the end. The scope is inserted down the throat into the stomach.</p><p>Your health care provider sends the tissue sample to a laboratory where it is examined for signs of cancer, certain infections, or other problems.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How to Prepare for the Test</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Follow instructions on how to prepare for the procedure. You will likely be asked not to eat or drink anything for 6 to 12 hours before the procedure. </p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test will Feel</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>Your provider will tell you what to expect during the procedure.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Why the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>This test may be done to diagnose a <a test="test" href="./000206.htm">stomach ulcer</a> or the cause of other stomach symptoms. These symptoms may include:</p><ul><li>Loss of appetite or weight loss</li><li>Nausea and vomiting</li><li>Pain in the upper part of the belly</li><li>Black stools</li><li>Vomiting blood or coffee ground-like material </li></ul><p>A gastric tissue biopsy and culture can help detect:</p><ul><li>Cancer</li><li>Infections, most commonly <a test="test" href="./007715.htm">Helicobacter pylori</a>, the bacteria that can cause stomach or intestinal ulcers </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Normal Results</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>A gastric tissue biopsy is normal if it does not show cancer, other damage to the lining of the stomach, or signs of organisms that cause infection.</p><p>A gastric tissue culture may be considered normal if it does not show certain bacteria. Stomach acids normally prevent too much bacteria from growing.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>What Abnormal Results Mean</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>Abnormal results may be due to:</p><ul><li><a test="test" href="./000223.htm">Stomach (gastric) cancer</a></li><li><a test="test" href="./001150.htm">Gastritis</a>, when the lining of the stomach becomes inflamed or swollen</li><li><em>Helicobacter pylori</em> infection </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Risks</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>Your provider will discuss the risks of the upper endoscopy procedure with you.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Culture - gastric tissue; Culture - stomach tissue; Biopsy - gastric tissue; Biopsy - stomach tissue; Upper endoscopy - gastric tissue biopsy; EGD - gastric tissue biopsy </p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Images</h2></div><div class="section-button"><button type="submit" aria-controls="section-tnails" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/9343t.jpg" alt="Culture of gastric tissue biopsy" title="Culture of gastric tissue biopsy" class="side-img"/><a href="../imagepages/9343.htm">Culture of gastric tissue biopsy</a></li>
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/24351t.jpg" alt="Esophagogastroduodenoscopy (EGD)" title="Esophagogastroduodenoscopy (EGD)" class="side-img"/><a href="../imagepages/19930.htm">Esophagogastroduodenoscopy (EGD)</a></li>
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</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Feldman M, Jensen PJ, Howden CW. Gastritis and gastropathy. In: Feldman M, Friedman LS, Brandt LJ, eds. <em>Sleisenger & Fordtran's Gastrointestinal and Liver Disease</em>. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 52.</p><p>Sugumar A, Vargo JJ. Preparation for and complications of GI endoscopy. In: Feldman M, Friedman LS, Brandt LJ, eds. <em>Sleisenger & Fordtran's Gastrointestinal and Liver Disease</em>. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 42.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 10/13/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
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</div></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Related MedlinePlus Health Topics</h2></div><div class="section-button"><button type="submit" aria-controls="section-mtp" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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