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</div><div><span>Latex agglutination test</span></div></div>
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</a><h1 class="with-also" itemprop="name">Latex agglutination test</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>The latex agglutination test is a test done in a lab to check for certain <a test="test" href="./002223.htm">antibodies</a> or <a test="test" href="./002224.htm">antigens</a> in body fluids including saliva, urine, cerebrospinal fluid, or blood.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>The test depends on what type of sample is needed.</p><ul><li>Saliva</li><li><a test="test" href="./007487.htm">Urine</a></li><li><a test="test" href="./003423.htm">Blood</a></li><li>Cerebrospinal fluid (<a test="test" href="./003428.htm">lumbar puncture</a>)</li></ul><p>The sample is sent to a lab, where it is mixed with latex beads coated with a specific antibody or antigen. If the suspected substance is present, the latex beads will clump together (agglutinate).</p><p>Latex agglutination results take about 15 minutes to an hour.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How to Prepare for the Test</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Your health care provider may tell you to limit certain foods or medicines shortly before the test. Follow instructions on how to prepare for the test.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Why the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>This test is a quick way to find out if an antigen or antibody is present or not. Your provider will base your treatment, in part, on the results of this test.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Normal Results</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>What Abnormal Results Mean</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>If there is an antigen-antibody match, agglutination will occur.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Risks</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>The risk level depends on the type of test.</p><p>URINE AND SALIVA TESTS</p><p>There is no risk with the urine or saliva test.</p><p>BLOOD TEST</p><p>Veins and arteries vary in size from one person to another and from one side of the body to the other. Getting a blood sample from some people may be more difficult than from others.</p><p>Other risks from having blood drawn are slight, but may include:</p><ul><li>Excessive bleeding</li><li><a test="test" href="./003092.htm">Fainting</a> or feeling lightheaded</li><li>
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Blood accumulating under the skin (<a test="test" href="./007213.htm">hematoma</a>)</li><li>Infection (a slight risk any time the skin is broken)</li></ul><p>CEREBROSPINAL FLUID TEST</p><p>Risks of lumbar puncture include:</p><ul><li>
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Bleeding into the spinal canal or around the brain (<a test="test" href="./000713.htm">subdural hematomas</a>).</li><li>Discomfort during the test.</li><li>Headache after the test that can last a few hours or days. If headaches last more than a few days (especially when you sit, stand or walk) you might have a "CSF-leak". You should talk to your provider if this occurs.</li><li>Hypersensitivity (allergic) reaction to the anesthetic.</li><li>Infection introduced by the needle going through the skin.</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Aoyagi K, Ashihara Y, Kasahara Y. Immunoassays and immunochemistry. In: McPherson RA, Pincus MR, eds. <em>Henry's Clinical Diagnosis and Management by Laboratory Methods</em>. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 45.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 9/18/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Anna C. Edens Hurst, MD, MS, Associate Professor in Medical Genetics, The University of Alabama at Birmingham, Birmingham, AL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
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