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</div><div><span>Chromosome</span></div></div>
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<article><div id="d-article"><div class="page-info"><div class="page-title"><a name="start" id="start">
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</a><h1 class="with-also" itemprop="name">Chromosome</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Chromosomes are structures found in the center (nucleus) of cells that carry long pieces of DNA. DNA is the material that holds <a test="test" href="./002371.htm">genes</a>. It is the building block of the human body.</p><p>Chromosomes also contain proteins that help DNA exist in the proper form. </p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>Information</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>Chromosomes come in pairs. Normally, each cell in the human body has 23 pairs of chromosomes (46 total chromosomes). Half come from the mother; the other half come from the father.</p><p>Two of the chromosomes (the X and the Y chromosome) are called sex chromosomes, and in almost all people:</p><ul><li>Females have 2 X chromosomes.</li><li>Males have 1 X and 1 Y chromosome. </li></ul><p>At conception, the mother gives an X chromosome to the child, and the father may contribute an X or a Y. The chromosome from the father determines if the baby is female or male. In most cases, a child is born as a male or female according to their chromosomes. However, children with <a test="test" href="./001669.htm">differences of sex development</a> may be born with genitalia that do not match their chromosomes. Or they may have fewer or more than 46 chromosomes. All of these conditions can cause problems with sexual development.</p><p>The remaining chromosomes are called autosomal chromosomes. They are known as chromosome pairs 1 through 22.</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Images</h2></div><div class="section-button"><button type="submit" aria-controls="section-tnails" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/8770t.jpg" alt="Chromosomes and DNA" title="Chromosomes and DNA" class="side-img"/><a href="../imagepages/8770.htm">Chromosomes and DNA</a></li>
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</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Perle MA, Stein CH. Applications of cytogenetics in modern pathology. In: McPherson RA, Pincus MR, eds. <em>Henry's Clinical Diagnosis and Management by Laboratory Methods</em>. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 71.</p><p><em>Taber's Cyclopedic Medical Dictionary</em>. 24th ed. F.A. Davis Company; 2021. <a href="https://www.tabers.com/tabersonline" target="_blank">www.tabers.com/tabersonline</a>. Accessed June 12, 2023.<br/></p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 4/27/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 11/16/2023.</p>
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