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</div><div><span>Acute respiratory distress syndrome</span></div></div>
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</a><h1 class="with-also" itemprop="name">Acute respiratory distress syndrome</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that prevents enough oxygen from getting to the lungs and into the blood. Infants can also have <a test="test" href="./001563.htm">respiratory distress syndrome</a>.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>Causes</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>ARDS can be caused by any major direct or indirect injury to the lung. Common causes include:</p><ul><li>Breathing vomit into the lungs (<a test="test" href="./002216.htm">aspiration</a>)</li><li>
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Inhaling chemicals
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</li><li>
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Lung transplant
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</li><li><a test="test" href="./000145.htm">Pneumonia</a>, including COVID-19 infection</li><li><a test="test" href="./000668.htm">Septic shock</a> (infection throughout the body)
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</li><li>Transfusions (multiple)</li><li>
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Trauma
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</li></ul><p>Depending on the amount of oxygen in the blood and during breathing, the severity of ARDS is classified as:</p><ul><li>Mild</li><li>Moderate</li><li>Severe</li></ul><p>ARDS leads to a buildup of fluid in the air sacs (alveoli). This fluid prevents enough oxygen from passing into the bloodstream.</p><p>The fluid buildup also makes the lungs heavy and stiff. This decreases the lungs' ability to expand. The level of oxygen in the blood can stay dangerously low, even if the person receives oxygen from a breathing machine (<a test="test" href="../patientinstructions/000458.htm">ventilator</a>) through a breathing tube (endotracheal tube).</p><p>ARDS often occurs along with the failure of other organ systems, such as the heart, liver or <a test="test" href="./000501.htm">kidneys</a>. Cigarette smoking and heavy alcohol use may be risk factors for its development.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Symptoms</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Symptoms usually develop within 24 to 48 hours of the injury or illness. Often, people with ARDS are so sick they cannot report symptoms. Symptoms can include any of the following:</p><ul><li>Shortness of breath</li><li>Fast heartbeat</li><li>Low blood pressure and organ failure</li><li>Rapid breathing</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Exams and Tests</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>Listening to the chest with a stethoscope (<a test="test" href="./002226.htm">auscultation</a>) reveals abnormal breath sounds, such as crackles, which may be signs of fluid in the lungs. Often, blood pressure is low. Blue skin, lips, and nails caused by lack of oxygen to the tissues (<a test="test" href="./003215.htm">cyanosis</a>) is often seen.</p><p>Tests used to diagnose ARDS include:</p><ul><li><a test="test" href="./003855.htm">Arterial blood gas</a></li><li>Blood tests, including <a test="test" href="./003642.htm">CBC</a> (complete blood count) and blood chemistries</li><li><a test="test" href="./003744.htm">Blood</a> and <a test="test" href="./003751.htm">urine</a> cultures</li><li><a test="test" href="./003857.htm">Bronchoscopy</a> in some people</li><li><a test="test" href="./003804.htm">Chest x-ray</a> or CT scan</li><li><a test="test" href="./003723.htm">Sputum cultures</a> and analysis</li><li>Tests for possible infections </li></ul><p>An <a test="test" href="./003869.htm">echocardiogram</a> may be needed to rule out <a test="test" href="./000158.htm">heart failure</a>, which can look similar to ARDS on a chest x-ray.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Treatment</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>ARDS often needs to be treated in an intensive care unit (ICU).</p><p>The goal of treatment is to provide breathing support and treat the cause of ARDS. This may involve medicines to treat infections, reduce inflammation, and remove fluid from the lungs.</p><p>A ventilator is used to deliver high doses of oxygen and positive pressure to the damaged lungs. People often need to be deeply sedated with medicines. During treatment, your health care providers make every effort to protect your lungs from further damage. Certain ways of using the ventilator can protect your lungs better and improve chances of recovery. Treatment is mainly supportive until the lungs recover.</p><p>Sometimes, a treatment called extracorporeal membrane oxygenation (ECMO) is done. During ECMO, blood is filtered through a machine to provide oxygen and remove carbon dioxide.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Support Groups</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>Many family members of people with ARDS are under extreme stress. They can often relieve this stress by joining <a test="test" href="./002158.htm">support groups</a> where members share common experiences and problems.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Outlook (Prognosis)</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>About one third of people with ARDS die of the disease. Those who live often get back most of their normal lung function, but many people have permanent (usually mild) lung damage.</p><p>Many people who survive ARDS have memory loss or other quality-of-life problems after they recover. This is due to brain damage that occurred when the lungs were not working properly and the brain was not getting enough oxygen. Some people can also have post-traumatic stress after surviving ARDS.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Possible Complications</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>Problems that may result from ARDS or its treatment include:</p><ul><li>Failure of many organ systems</li><li>Lung damage, such as a collapsed lung (also called <a test="test" href="./000087.htm">pneumothorax</a>) due to injury from the breathing machine needed to treat the disease</li><li><a test="test" href="./000069.htm">Pulmonary fibrosis</a> (scarring of the lung)</li><li><a test="test" href="./000146.htm">Ventilator-associated pneumonia</a></li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>When to Contact a Medical Professional</h2></div><div class="section-button"><button type="submit" aria-controls="section-8" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-8"><p>ARDS most often occurs during another illness, for which the person is already in the hospital. In some cases, a healthy person has severe pneumonia that gets worse and becomes ARDS. If you have trouble breathing, call your local emergency number (such as 911) or go to the emergency room.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Noncardiogenic pulmonary edema; Increased-permeability pulmonary edema; ARDS; Acute lung injury</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Patient Instructions</h2></div><div class="section-button"><button type="submit" aria-controls="section-carepnt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Binnie A, Herridge MS, Lee WL. Acute respiratory distress syndrome. In: Broaddus VC, Ernst JD, King TE, et al, eds. <em>Murray and Nadel's Textbook of Respiratory Medicine</em>. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 134.</p><p>Matthay MA, Ware LB. Acute respiratory failure. In: Goldman L, Cooney KA, eds. <em>Goldman-Cecil Medicine</em>. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 90.</p><p>Seigel TA, Johnson NJ. Mechanical ventilation and noninvasive ventilatory support. In: Walls RM, ed. <em>Rosen's Emergency Medicine: Concepts and Clinical Practice</em>. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 2.</p></div></div></section>
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