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<h1>tRNA modification</h1>
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<a class="usa-button" href="#" onclick="download_table_as_tsv('pathway_result_table');">Download</a>
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<table id="pathway_result_table" data-jig="ncbigrid">
<thead>
<tr>
<th>COG</th>
<th>Funtional Cat</th>
<th>COG symbol</th>
<th>Name</th>
<th>EC</th>
</tr>
</thead>
<tbody>
<tr>
<td><a href="/research/cog/cog/COG0042/">COG0042</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=DusA"
target="_blank">DusA</a>
</td>
<td>tRNA-dihydrouridine synthase</td>
<td>EC 1.3.1.91</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0324/">COG0324</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=MiaA"
target="_blank">MiaA</a>
</td>
<td>tRNA A37 N6-isopentenylltransferase MiaA</td>
<td>EC 2.5.1.75</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0621/">COG0621</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=MiaB"
target="_blank">MiaB</a>
</td>
<td>tRNA A37 methylthiotransferase MiaB</td>
<td>EC 2.8.4.3</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG4445/">COG4445</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=MiaE"
target="_blank">MiaE</a>
</td>
<td>tRNA A37 isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1214/">COG1214</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TsaB"
target="_blank">TsaB</a>
</td>
<td>tRNA A37 threonylcarbamoyladenosine modification protein TsaB</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0009/">COG0009</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TsaC"
target="_blank">TsaC</a>
</td>
<td>tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC</td>
<td>EC 2.7.7.87</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0533/">COG0533</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TsaD"
target="_blank">TsaD</a>
</td>
<td>tRNA A37 threonylcarbamoyltransferase TsaD</td>
<td>EC 2.3.1.234</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0802/">COG0802</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TsaE"
target="_blank">TsaE</a>
</td>
<td>tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1179/">COG1179</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TcdA"
target="_blank">TcdA</a>
</td>
<td>tRNA A37 threonylcarbamoyladenosine dehydratase</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG3642/">COG3642</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Bud32"
target="_blank">Bud32</a>
</td>
<td>tRNA A37 N6-threonylcarbamoyl transferase component Bud32</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2892/">COG2892</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Pcc1"
target="_blank">Pcc1</a>
</td>
<td>tRNA A37 N6-threonylcarbamoyladenosine modification (KEOPS) complex, Pcc1 subunit</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1041/">COG1041</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Trm11"
target="_blank">Trm11</a>
</td>
<td>tRNA G10 N-methylase Trm11</td>
<td>EC 2.1.1.214</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0220/">COG0220</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmB"
target="_blank">TrmB</a>
</td>
<td>tRNA G46 N7-methylase TrmB</td>
<td>EC 2.1.1.33</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0336/">COG0336</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmD"
target="_blank">TrmD</a>
</td>
<td>tRNA G37 N-methylase TrmD</td>
<td>EC 2.1.1.228</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0482/">COG0482</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=MnmA"
target="_blank">MnmA</a>
</td>
<td>tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain</td>
<td>EC 2.8.1.13</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG4121/">COG4121</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=MnmC"
target="_blank">MnmC</a>
</td>
<td>tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC</td>
<td>EC 2.1.1.61</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0486/">COG0486</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=MnmE"
target="_blank">MnmE</a>
</td>
<td>tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0445/">COG0445</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=MnmG"
target="_blank">MnmG</a>
</td>
<td>tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0617/">COG0617</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=PcnB"
target="_blank">PcnB</a>
</td>
<td>tRNA nucleotidyltransferase (CCA-adding enzyme)/poly(A) polymerase</td>
<td>EC 2.7.7.72</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0809/">COG0809</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=QueA"
target="_blank">QueA</a>
</td>
<td>S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)</td>
<td>EC 2.4.99.17</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0603/">COG0603</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=QueC"
target="_blank">QueC</a>
</td>
<td>7-cyano-7-deazaguanine synthase (queuosine biosynthesis)</td>
<td>EC 6.3.4.20</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0720/">COG0720</a></td>
<td>
H
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=QueD"
target="_blank">QueD</a>
</td>
<td>6-pyruvoyl-tetrahydropterin synthase</td>
<td>EC 4.1.2.50</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0602/">COG0602</a></td>
<td>
H
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=QueE"
target="_blank">QueE</a>
</td>
<td>Organic radical activating enzyme, includes 7-carboxy-7-deazaguanine synthase NrdG/QueE</td>
<td>EC:4.3.99.3</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0780/">COG0780</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=QueFC"
target="_blank">QueFC</a>
</td>
<td>NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily</td>
<td>EC 1.7.1.13</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1600/">COG1600</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=QueG"
target="_blank">QueG</a>
</td>
<td>Epoxyqueuosine reductase QueG (queuosine biosynthesis)</td>
<td>EC 1.17.99.6</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1746/">COG1746</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=CCA1"
target="_blank">CCA1</a>
</td>
<td>tRNA nucleotidyltransferase (archaeal CCA-adding enzyme)</td>
<td>EC 2.7.7.72</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1617/">COG1617</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Cgi121"
target="_blank">Cgi121</a>
</td>
<td>tRNA threonylcarbamoyladenosine modification (KEOPS) complex, Cgi121 subunit</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2519/">COG2519</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Gcd14"
target="_blank">Gcd14</a>
</td>
<td>tRNA A57/A58 N1-methylase Trm61</td>
<td>EC 2.1.1.220</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1258/">COG1258</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Pus10"
target="_blank">Pus10</a>
</td>
<td>tRNA U54 and U55 pseudouridine synthase Pus10</td>
<td>EC 5.4.99.25</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1676/">COG1676</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=SEN2"
target="_blank">SEN2</a>
</td>
<td>tRNA splicing endonuclease subunit SEN34</td>
<td>EC 4.6.1.16</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2603/">COG2603</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=SelU"
target="_blank">SelU</a>
</td>
<td>tRNA U34 2-selenouridine synthase SelU, contains rhodanese domain</td>
<td>EC 2.5.1.-</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0566/">COG0566</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=SpoU"
target="_blank">SpoU</a>
</td>
<td>tRNA G18 (ribose-2&#x27;-O)-methylase SpoU</td>
<td>EC 2.1.1.34</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0590/">COG0590</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TadA"
target="_blank">TadA</a>
</td>
<td>tRNA(Arg) A34 adenosine deaminase TadA</td>
<td>EC 3.5.4.33</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1818/">COG1818</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Tan1"
target="_blank">Tan1</a>
</td>
<td>tRNA(Ser,Leu) C12 N-acetylase TAN1, contains THUMP domain</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1187/">COG1187</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=RluF"
target="_blank">RluF</a>
</td>
<td>Pseudouridylate synthase RsuA/RluF, specific for 16S rRNA U516, 23S rRNA U2604/U2605/U2457, and tRNA(Tyr)-35</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0343/">COG0343</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Tgt"
target="_blank">Tgt</a>
</td>
<td>Queuine/archaeosine tRNA-ribosyltransferase</td>
<td>EC 2.4.2.29</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG4021/">COG4021</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Thg1"
target="_blank">Thg1</a>
</td>
<td>tRNA(His) 5&#x27;-end guanylyltransferase/3&#x27;-5&#x27; nucleotidyltransferase</td>
<td>EC 2.7.7.79</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1571/">COG1571</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TiaS"
target="_blank">TiaS</a>
</td>
<td>tRNA(Ile2) C34 agmatinyltransferase TiaS</td>
<td>EC 6.3.4.22</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0037/">COG0037</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TilS"
target="_blank">TilS</a>
</td>
<td>tRNA-C32 2-thiocytidine or tRNA(Ile)-C34 C2-lysylcytidine synthase TtcA/TilS/MesJ</td>
<td>EC 6.3.4.19;EC 2.8.1.-</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1444/">COG1444</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TmcA"
target="_blank">TmcA</a>
</td>
<td>tRNA(Met) C34 N-acetyltransferase TmcA</td>
<td>EC 2.3.1.193</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1323/">COG1323</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TmcAL"
target="_blank">TmcAL</a>
</td>
<td>tRNA-Met C34-N4-acetylcytidine synthase TmcAL</td>
<td>EC 6.3.4.-</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG5324/">COG5324</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Trl1"
target="_blank">Trl1</a>
</td>
<td>tRNA splicing ligase</td>
<td>None</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0144/">COG0144</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Trm4"
target="_blank">Trm4</a>
</td>
<td>RNA cytosine C5-methylase, RsmB/RsmF/Trm4/Trm9 family, includes 16S rRNA C967/C1407 and tRNA-C34/C48 C5-methylases</td>
<td>EC:2.1.1.229;EC 2.1.1.-</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2520/">COG2520</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Trm5"
target="_blank">Trm5</a>
</td>
<td>tRNA G37 N1-methylase Trm5</td>
<td>EC 2.1.1.228</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0293/">COG0293</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Trm7"
target="_blank">Trm7</a>
</td>
<td>23S rRNA U2552 or 16S rRNA-U1369 or eukaryotic tRNA-C32/G34 (ribose-2&#x27;-O)-methylase RlmE/FtsJ/TRM7</td>
<td>EC 2.1.1.205</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2265/">COG2265</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmA"
target="_blank">TrmA</a>
</td>
<td>tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family</td>
<td>EC 2.1.1.35;EC 2.1.1.189;EC 2.1.1.190</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1206/">COG1206</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmFO"
target="_blank">TrmFO</a>
</td>
<td>Folate-dependent tRNA-U54 methylase TrmFO/GidA</td>
<td>EC 2.1.1.74</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0565/">COG0565</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmJ"
target="_blank">TrmJ</a>
</td>
<td>tRNA C32,U32 (ribose-2&#x27;-O)-methylase TrmJ or a related methyltransferase</td>
<td>EC 2.1.1.200</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0270/">COG0270</a></td>
<td>
J
,
L
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Dcm"
target="_blank">Dcm</a>
</td>
<td>DNA-cytosine methylase Dcm or eukaryotic tRNA-C38 C5-methylase, Dcm/DNMT2/TRDMT1 family</td>
<td>EC 2.1.1.204</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0500/">COG0500</a></td>
<td>
Q
,
R
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=CmoB"
target="_blank">CmoB</a>
</td>
<td>SAM-dependent methyltransferase SmtA (CmoB moved to COG2228)</td>
<td>EC 2.5.1.-</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2227/">COG2227</a></td>
<td>
H
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=CmoM"
target="_blank">CmoM</a>
</td>
<td>2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase</td>
<td>EC:2.1.1.-</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1187/">COG1187</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TapT"
target="_blank">TapT</a>
</td>
<td>Pseudouridylate synthase RsuA/RluF, specific for 16S rRNA U516, 23S rRNA U2604/U2605/U2457, and tRNA(Tyr)-35</td>
<td>EC:2.5.1.25</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2384/">COG2384</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmK"
target="_blank">TrmK</a>
</td>
<td>tRNA A22 N1-methylase</td>
<td>EC 2.1.1.217</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0219/">COG0219</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmL"
target="_blank">TrmL</a>
</td>
<td>tRNA(Leu) C34 or U34 (ribose-2&#x27;-O)-methylase TrmL, contains SPOUT domain</td>
<td>EC 2.1.1.207</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG4123/">COG4123</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmN6"
target="_blank">TrmN6</a>
</td>
<td>tRNA1(Val) A37 N6-methylase TrmN6</td>
<td>EC 2.1.1.223</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1720/">COG1720</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmO"
target="_blank">TrmO</a>
</td>
<td>tRNA (Thr-GGU) A37 N6-methylase</td>
<td>EC 2.1.1.-</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG4122/">COG4122</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmR"
target="_blank">TrmR</a>
</td>
<td>tRNA 5-hydroxyU34 O-methylase TrmR/YrrM</td>
<td>EC 2.1.1.-</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1901/">COG1901</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TrmY"
target="_blank">TrmY</a>
</td>
<td>tRNA pseudouridine-54 N-methylase</td>
<td>EC 2.1.1.257</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1867/">COG1867</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Trm1"
target="_blank">Trm1</a>
</td>
<td>tRNA G26 N,N-dimethylase Trm1</td>
<td>EC 2.1.1.216</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2419/">COG2419</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Trm10"
target="_blank">Trm10</a>
</td>
<td>tRNA (A,G)9-N1-methylase TRM10</td>
<td>EC 2.1.1.218</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0116/">COG0116</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Trm14"
target="_blank">Trm14</a>
</td>
<td>RNA guanine methylase, includes 23S rRNA G2445 N2-methylase RlmL and tRNA-G6 N2-methylase Trm14</td>
<td>EC 2.1.1.256</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0101/">COG0101</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TruA"
target="_blank">TruA</a>
</td>
<td>tRNA U38,U39,U40 pseudouridine synthase TruA</td>
<td>EC 5.4.99.12</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0130/">COG0130</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TruB"
target="_blank">TruB</a>
</td>
<td>tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA</td>
<td>EC 5.4.99.25</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0585/">COG0585</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=TruD"
target="_blank">TruD</a>
</td>
<td>tRNA(Glu) U13 pseudouridine synthase TruD</td>
<td>EC 5.4.99.27</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG0731/">COG0731</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Tyw1"
target="_blank">Tyw1</a>
</td>
<td>Wyosine [tRNA(Phe)-imidazoG37] synthetase, radical SAM superfamily</td>
<td>EC 4.1.3.44</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG1590/">COG1590</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term=Tyw3"
target="_blank">Tyw3</a>
</td>
<td>tRNA(Phe) wybutosine-synthesizing methylase Tyw3</td>
<td>EC 2.1.1.282</td>
</tr>
<tr>
<td><a href="/research/cog/cog/COG2117/">COG2117</a></td>
<td>
J
</td>
<td>
<a href="https://www.ncbi.nlm.nih.gov/gene/?term="
target="_blank"></a>
</td>
<td>Adenosine-binding enzyme, AANH-like superfamily</td>
<td>None</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</section>
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