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K - NCBI
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Updated: February, 2025
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<span class="headername">Database of Clusters of Orthologous Genes (COGs)</span>
<ul data-jig="ncbimenu" id="ui-ncbimenu-1" role="menubar">
<li role="presentation" class="no-submenu">
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COG Database
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COG Categories
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<ul style="display:none" id="menu-categories">
<a href="/research/cog/cogcategory/J/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
J - Translation, ribosomal structure and biogenesis</a>
<a href="/research/cog/cogcategory/A/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
A - RNA processing and modification</a>
<a href="/research/cog/cogcategory/K/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
K - Transcription</a>
<a href="/research/cog/cogcategory/L/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
L - Replication, recombination and repair</a>
<a href="/research/cog/cogcategory/B/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
B - Chromatin structure and dynamics</a>
<a href="/research/cog/cogcategory/D/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
D - Cell cycle control, cell division, chromosome partitioning</a>
<a href="/research/cog/cogcategory/Y/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
Y - Nuclear structure</a>
<a href="/research/cog/cogcategory/V/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
V - Defense mechanisms</a>
<a href="/research/cog/cogcategory/T/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
T - Signal transduction mechanisms</a>
<a href="/research/cog/cogcategory/M/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
M - Cell wall/membrane/envelope biogenesis</a>
<a href="/research/cog/cogcategory/N/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
N - Cell motility</a>
<a href="/research/cog/cogcategory/Z/" title="COG Categories"
class="uppercase"
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id="ui-ncbimenu-1_2">
Z - Cytoskeleton</a>
<a href="/research/cog/cogcategory/W/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
W - Extracellular structures</a>
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class="uppercase"
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style="font-weight: normal;"
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U - Intracellular trafficking, secretion, and vesicular transport</a>
<a href="/research/cog/cogcategory/O/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
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O - Posttranslational modification, protein turnover, chaperones</a>
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class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
X - nan</a>
<a href="/research/cog/cogcategory/C/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
C - Energy production and conversion</a>
<a href="/research/cog/cogcategory/G/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
G - Carbohydrate transport and metabolism</a>
<a href="/research/cog/cogcategory/E/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
E - Amino acid transport and metabolism</a>
<a href="/research/cog/cogcategory/F/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
F - Nucleotide transport and metabolism</a>
<a href="/research/cog/cogcategory/H/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
H - Coenzyme transport and metabolism</a>
<a href="/research/cog/cogcategory/I/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
I - Lipid transport and metabolism</a>
<a href="/research/cog/cogcategory/P/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
P - Inorganic ion transport and metabolism</a>
<a href="/research/cog/cogcategory/Q/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
Q - Secondary metabolites biosynthesis, transport and catabolism</a>
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style="font-weight: normal;"
id="ui-ncbimenu-1_2">
R - General function prediction only</a>
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class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
S - Function unknown</a>
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</div>
<main id="main_content" accesskey="3">
<section class="usa-section cog_top_section">
<div class="usa-grid">
<h1>K<span style='font-weight: 100'> - Transcription</span></h1>
<div style="float: right; clear: both;margin-top: -53px;">
<a class="usa-button" href="#" onclick="download_table_as_tsv('cog_result_table');">Download</a>
</div>
<h2>Stats</h2>
<div style="width: 60%">
<div class="ui-ncbigrid-outer-div organism_cog_table">
<div class="ui-ncbigrid-inner-div">
<table data-jig="ncbigrid">
<thead>
<tr>
<th>COG<br>definitions</th>
<th>Organims</th>
<th>Proteins</th>
<th>Median Protein<br>Length</th>
<th>Genes</th>
</tr>
</thead>
<tbody>
<tr>
<td>224</td>
<td>2,296</td>
<td>470,333</td>
<td>232.0</td>
<td>191</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="ui-ncbigrid-outer-div" style="font-size: 80%;">
<div class="ui-ncbigrid-inner-div">
<table id="cog_result_table" data-jig="ncbigrid">
<thead>
<tr>
<th>Organism</th>
<th>Protein</th>
<th>COG</th>
<th>Cat</th>
<th>Annotation</th>
</tr>
</thead>
<tbody>
<tr>
<td>2256</td>
<td>2412</td>
<td><a href="/research/cog/cog/COG0085/">COG0085</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, beta subunit/140 kD subunit</td>
</tr>
<tr>
<td>2250</td>
<td>2521</td>
<td><a href="/research/cog/cog/COG0086/">COG0086</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, beta&#x27; subunit/160 kD subunit</td>
</tr>
<tr>
<td>2251</td>
<td>2322</td>
<td><a href="/research/cog/cog/COG0195/">COG0195</a></td>
<td>
K
</td>
<td>Transcription antitermination factor NusA, contains S1 and KH domains</td>
</tr>
<tr>
<td>2258</td>
<td>2368</td>
<td><a href="/research/cog/cog/COG0202/">COG0202</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, alpha subunit/40 kD subunit</td>
</tr>
<tr>
<td>2051</td>
<td>2219</td>
<td><a href="/research/cog/cog/COG0217/">COG0217</a></td>
<td>
J
K
</td>
<td>Transcriptional and/or translational regulatory protein YebC/TACO1</td>
</tr>
<tr>
<td>2268</td>
<td>2839</td>
<td><a href="/research/cog/cog/COG0250/">COG0250</a></td>
<td>
K
</td>
<td>Transcription termination/antitermination protein NusG</td>
</tr>
<tr>
<td>869</td>
<td>1153</td>
<td><a href="/research/cog/cog/COG0271/">COG0271</a></td>
<td>
K
T
</td>
<td>DNA-binding global transcriptional regulator BolA, affects cell shape, cell division and biofilm formation</td>
</tr>
<tr>
<td>1992</td>
<td>3169</td>
<td><a href="/research/cog/cog/COG0317/">COG0317</a></td>
<td>
K
T
</td>
<td>(p)ppGpp synthase/hydrolase, HD superfamily</td>
</tr>
<tr>
<td>115</td>
<td>124</td>
<td><a href="/research/cog/cog/COG0454/">COG0454</a></td>
<td>
K
R
</td>
<td>N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)</td>
</tr>
<tr>
<td>1491</td>
<td>3044</td>
<td><a href="/research/cog/cog/COG0553/">COG0553</a></td>
<td>
K
L
</td>
<td>Superfamily II DNA or RNA helicase, SNF2 family</td>
</tr>
<tr>
<td>1844</td>
<td>2255</td>
<td><a href="/research/cog/cog/COG0557/">COG0557</a></td>
<td>
K
</td>
<td>Exoribonuclease R</td>
</tr>
<tr>
<td>2086</td>
<td>4965</td>
<td><a href="/research/cog/cog/COG0568/">COG0568</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)</td>
</tr>
<tr>
<td>2068</td>
<td>2168</td>
<td><a href="/research/cog/cog/COG0571/">COG0571</a></td>
<td>
K
</td>
<td>dsRNA-specific ribonuclease</td>
</tr>
<tr>
<td>1902</td>
<td>34485</td>
<td><a href="/research/cog/cog/COG0583/">COG0583</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, LysR family</td>
</tr>
<tr>
<td>2064</td>
<td>10977</td>
<td><a href="/research/cog/cog/COG0640/">COG0640</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, ArsR family</td>
</tr>
<tr>
<td>1807</td>
<td>1918</td>
<td><a href="/research/cog/cog/COG0718/">COG0718</a></td>
<td>
K
</td>
<td>DNA-binding nucleoid-associated protein YbaB/EfbC</td>
</tr>
<tr>
<td>2126</td>
<td>31286</td>
<td><a href="/research/cog/cog/COG0745/">COG0745</a></td>
<td>
K
T
</td>
<td>DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain</td>
</tr>
<tr>
<td>2182</td>
<td>2501</td>
<td><a href="/research/cog/cog/COG0750/">COG0750</a></td>
<td>
K
O
</td>
<td>Membrane-associated protease RseP, regulator of RpoE activity</td>
</tr>
<tr>
<td>2078</td>
<td>2921</td>
<td><a href="/research/cog/cog/COG0781/">COG0781</a></td>
<td>
K
</td>
<td>Transcription antitermination protein NusB</td>
</tr>
<tr>
<td>1985</td>
<td>3481</td>
<td><a href="/research/cog/cog/COG0782/">COG0782</a></td>
<td>
K
</td>
<td>Transcription elongation factor, GreA/GreB family</td>
</tr>
<tr>
<td>1906</td>
<td>9983</td>
<td><a href="/research/cog/cog/COG0789/">COG0789</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, MerR family</td>
</tr>
<tr>
<td>1983</td>
<td>2075</td>
<td><a href="/research/cog/cog/COG0816/">COG0816</a></td>
<td>
J
K
L
</td>
<td>YqgF/RuvX protein, pre-16S rRNA maturation RNase/Holliday junction resolvase/anti-termination factor</td>
</tr>
<tr>
<td>627</td>
<td>899</td>
<td><a href="/research/cog/cog/COG0864/">COG0864</a></td>
<td>
K
</td>
<td>Metal-responsive transcriptional regulator, contains CopG/Arc/MetJ DNA-binding domain</td>
</tr>
<tr>
<td>1435</td>
<td>2810</td>
<td><a href="/research/cog/cog/COG1061/">COG1061</a></td>
<td>
K
L
</td>
<td>Superfamily II DNA or RNA helicase</td>
</tr>
<tr>
<td>192</td>
<td>192</td>
<td><a href="/research/cog/cog/COG1095/">COG1095</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, subunit E&#x27;/Rpb7</td>
</tr>
<tr>
<td>1818</td>
<td>1930</td>
<td><a href="/research/cog/cog/COG1158/">COG1158</a></td>
<td>
K
</td>
<td>Transcription termination factor Rho</td>
</tr>
<tr>
<td>1484</td>
<td>4772</td>
<td><a href="/research/cog/cog/COG1167/">COG1167</a></td>
<td>
K
E
</td>
<td>DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain</td>
</tr>
<tr>
<td>1096</td>
<td>1806</td>
<td><a href="/research/cog/cog/COG1191/">COG1191</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase specialized sigma subunit</td>
</tr>
<tr>
<td>1975</td>
<td>2011</td>
<td><a href="/research/cog/cog/COG1197/">COG1197</a></td>
<td>
K
L
</td>
<td>Transcription-repair coupling factor (superfamily II helicase)</td>
</tr>
<tr>
<td>104</td>
<td>111</td>
<td><a href="/research/cog/cog/COG1221/">COG1221</a></td>
<td>
K
T
</td>
<td>Transcriptional regulators containing sigma54-interacting ATPase domain</td>
</tr>
<tr>
<td>42</td>
<td>42</td>
<td><a href="/research/cog/cog/COG1224/">COG1224</a></td>
<td>
K
</td>
<td>DNA helicase TIP49, TBP-interacting protein</td>
</tr>
<tr>
<td>1871</td>
<td>5933</td>
<td><a href="/research/cog/cog/COG1278/">COG1278</a></td>
<td>
K
</td>
<td>Cold shock protein, CspA family</td>
</tr>
<tr>
<td>199</td>
<td>202</td>
<td><a href="/research/cog/cog/COG1308/">COG1308</a></td>
<td>
K
</td>
<td>Transcription factor homologous to NACalpha-BTF3</td>
</tr>
<tr>
<td>2048</td>
<td>31532</td>
<td><a href="/research/cog/cog/COG1309/">COG1309</a></td>
<td>
K
</td>
<td>DNA-binding protein, AcrR family, includes nucleoid occlusion protein SlmA</td>
</tr>
<tr>
<td>59</td>
<td>68</td>
<td><a href="/research/cog/cog/COG1318/">COG1318</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator</td>
</tr>
<tr>
<td>1283</td>
<td>2096</td>
<td><a href="/research/cog/cog/COG1321/">COG1321</a></td>
<td>
K
</td>
<td>Mn-dependent transcriptional regulator MntR, DtxR family</td>
</tr>
<tr>
<td>1669</td>
<td>1710</td>
<td><a href="/research/cog/cog/COG1327/">COG1327</a></td>
<td>
K
</td>
<td>Transcriptional regulator NrdR, contains Zn-ribbon and ATP-cone domains</td>
</tr>
<tr>
<td>834</td>
<td>911</td>
<td><a href="/research/cog/cog/COG1329/">COG1329</a></td>
<td>
K
</td>
<td>RNA polymerase-interacting regulator, CarD/CdnL/TRCF family</td>
</tr>
<tr>
<td>1254</td>
<td>4012</td>
<td><a href="/research/cog/cog/COG1349/">COG1349</a></td>
<td>
K
G
</td>
<td>DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family</td>
</tr>
<tr>
<td>82</td>
<td>93</td>
<td><a href="/research/cog/cog/COG1356/">COG1356</a></td>
<td>
K
</td>
<td>Transcriptional regulator</td>
</tr>
<tr>
<td>394</td>
<td>1051</td>
<td><a href="/research/cog/cog/COG1378/">COG1378</a></td>
<td>
K
</td>
<td>Sugar-specific transcriptional regulator TrmB</td>
</tr>
<tr>
<td>1638</td>
<td>1752</td>
<td><a href="/research/cog/cog/COG1386/">COG1386</a></td>
<td>
K
</td>
<td>Chromosome segregation and condensation protein ScpB</td>
</tr>
<tr>
<td>200</td>
<td>206</td>
<td><a href="/research/cog/cog/COG1395/">COG1395</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator</td>
</tr>
<tr>
<td>1935</td>
<td>14929</td>
<td><a href="/research/cog/cog/COG1396/">COG1396</a></td>
<td>
K
</td>
<td>Transcriptional regulator, contains XRE-family HTH domain</td>
</tr>
<tr>
<td>191</td>
<td>891</td>
<td><a href="/research/cog/cog/COG1405/">COG1405</a></td>
<td>
K
</td>
<td>Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB</td>
</tr>
<tr>
<td>1217</td>
<td>6204</td>
<td><a href="/research/cog/cog/COG1414/">COG1414</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, IclR family</td>
</tr>
<tr>
<td>1417</td>
<td>1425</td>
<td><a href="/research/cog/cog/COG1420/">COG1420</a></td>
<td>
K
</td>
<td>Transcriptional regulator of heat shock response</td>
</tr>
<tr>
<td>729</td>
<td>820</td>
<td><a href="/research/cog/cog/COG1438/">COG1438</a></td>
<td>
K
</td>
<td>Arginine repressor</td>
</tr>
<tr>
<td>186</td>
<td>188</td>
<td><a href="/research/cog/cog/COG1460/">COG1460</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, subunit F</td>
</tr>
<tr>
<td>1296</td>
<td>3280</td>
<td><a href="/research/cog/cog/COG1476/">COG1476</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, XRE-family HTH domain</td>
</tr>
<tr>
<td>647</td>
<td>649</td>
<td><a href="/research/cog/cog/COG1481/">COG1481</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator WhiA, involved in cell division</td>
</tr>
<tr>
<td>117</td>
<td>122</td>
<td><a href="/research/cog/cog/COG1497/">COG1497</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator MJ0558, contains a CRP-type HTH domain</td>
</tr>
<tr>
<td>1360</td>
<td>1466</td>
<td><a href="/research/cog/cog/COG1508/">COG1508</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog</td>
</tr>
<tr>
<td>571</td>
<td>771</td>
<td><a href="/research/cog/cog/COG1510/">COG1510</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator GbsR, MarR family</td>
</tr>
<tr>
<td>1782</td>
<td>9472</td>
<td><a href="/research/cog/cog/COG1522/">COG1522</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, Lrp family</td>
</tr>
<tr>
<td>115</td>
<td>179</td>
<td><a href="/research/cog/cog/COG1581/">COG1581</a></td>
<td>
K
B
</td>
<td>DNA/RNA-binding protein AlbA/Sso10b</td>
</tr>
<tr>
<td>206</td>
<td>347</td>
<td><a href="/research/cog/cog/COG1594/">COG1594</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS</td>
</tr>
<tr>
<td>1866</td>
<td>22302</td>
<td><a href="/research/cog/cog/COG1595/">COG1595</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase specialized sigma subunit, sigma24 family</td>
</tr>
<tr>
<td>1414</td>
<td>13436</td>
<td><a href="/research/cog/cog/COG1609/">COG1609</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, LacI/PurR family</td>
</tr>
<tr>
<td>191</td>
<td>191</td>
<td><a href="/research/cog/cog/COG1644/">COG1644</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, subunit N (RpoN/RPB10)</td>
</tr>
<tr>
<td>835</td>
<td>876</td>
<td><a href="/research/cog/cog/COG1654/">COG1654</a></td>
<td>
K
</td>
<td>Biotin operon repressor</td>
</tr>
<tr>
<td>169</td>
<td>172</td>
<td><a href="/research/cog/cog/COG1675/">COG1675</a></td>
<td>
K
</td>
<td>Transcription initiation factor IIE, alpha subunit</td>
</tr>
<tr>
<td>1151</td>
<td>1179</td>
<td><a href="/research/cog/cog/COG1678/">COG1678</a></td>
<td>
K
</td>
<td>Putative transcriptional regulator, AlgH/UPF0301 family</td>
</tr>
<tr>
<td>66</td>
<td>93</td>
<td><a href="/research/cog/cog/COG1693/">COG1693</a></td>
<td>
K
</td>
<td>Repressor of nif and glnA expression</td>
</tr>
<tr>
<td>1413</td>
<td>5042</td>
<td><a href="/research/cog/cog/COG1695/">COG1695</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, PadR family</td>
</tr>
<tr>
<td>183</td>
<td>186</td>
<td><a href="/research/cog/cog/COG1709/">COG1709</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator,contains XRE-type HTH domain</td>
</tr>
<tr>
<td>950</td>
<td>2074</td>
<td><a href="/research/cog/cog/COG1725/">COG1725</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator YhcF, GntR family</td>
</tr>
<tr>
<td>1490</td>
<td>4948</td>
<td><a href="/research/cog/cog/COG1733/">COG1733</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, HxlR family</td>
</tr>
<tr>
<td>1588</td>
<td>2654</td>
<td><a href="/research/cog/cog/COG1734/">COG1734</a></td>
<td>
K
</td>
<td>RNA polymerase-binding transcription factor DksA</td>
</tr>
<tr>
<td>1003</td>
<td>3100</td>
<td><a href="/research/cog/cog/COG1737/">COG1737</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains</td>
</tr>
<tr>
<td>1798</td>
<td>1809</td>
<td><a href="/research/cog/cog/COG1758/">COG1758</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, subunit K/omega</td>
</tr>
<tr>
<td>189</td>
<td>190</td>
<td><a href="/research/cog/cog/COG1761/">COG1761</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, subunit L/RPAC2</td>
</tr>
<tr>
<td>243</td>
<td>364</td>
<td><a href="/research/cog/cog/COG1777/">COG1777</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, ArsR family</td>
</tr>
<tr>
<td>390</td>
<td>449</td>
<td><a href="/research/cog/cog/COG1782/">COG1782</a></td>
<td>
K
</td>
<td>Transcription-terminating endoRNase FttA, contains metallo-beta-lactamase and KH domains</td>
</tr>
<tr>
<td>1273</td>
<td>7163</td>
<td><a href="/research/cog/cog/COG1802/">COG1802</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, GntR family</td>
</tr>
<tr>
<td>255</td>
<td>284</td>
<td><a href="/research/cog/cog/COG1827/">COG1827</a></td>
<td>
K
H
</td>
<td>Transcriptional regulator of NAD metabolism, contains HTH and 3H domains</td>
</tr>
<tr>
<td>1995</td>
<td>16130</td>
<td><a href="/research/cog/cog/COG1846/">COG1846</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, MarR family</td>
</tr>
<tr>
<td>1095</td>
<td>1744</td>
<td><a href="/research/cog/cog/COG1937/">COG1937</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, FrmR family</td>
</tr>
<tr>
<td>1738</td>
<td>6428</td>
<td><a href="/research/cog/cog/COG1940/">COG1940</a></td>
<td>
K
G
</td>
<td>Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain</td>
</tr>
<tr>
<td>230</td>
<td>283</td>
<td><a href="/research/cog/cog/COG1954/">COG1954</a></td>
<td>
K
</td>
<td>Glycerol-3-phosphate responsive antiterminator (mRNA-binding)</td>
</tr>
<tr>
<td>186</td>
<td>319</td>
<td><a href="/research/cog/cog/COG1958/">COG1958</a></td>
<td>
K
</td>
<td>Small nuclear ribonucleoprotein (snRNP) homolog</td>
</tr>
<tr>
<td>1789</td>
<td>4399</td>
<td><a href="/research/cog/cog/COG1959/">COG1959</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, IscR family</td>
</tr>
<tr>
<td>1752</td>
<td>2751</td>
<td><a href="/research/cog/cog/COG1974/">COG1974</a></td>
<td>
K
T
</td>
<td>SOS-response transcriptional repressor LexA (RecA-mediated autopeptidase)</td>
</tr>
<tr>
<td>911</td>
<td>1406</td>
<td><a href="/research/cog/cog/COG1983/">COG1983</a></td>
<td>
K
T
</td>
<td>Phage shock protein PspC (stress-responsive transcriptional regulator)</td>
</tr>
<tr>
<td>312</td>
<td>353</td>
<td><a href="/research/cog/cog/COG1996/">COG1996</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, subunit RPC12/RpoP, contains C4-type Zn-finger</td>
</tr>
<tr>
<td>577</td>
<td>1017</td>
<td><a href="/research/cog/cog/COG2002/">COG2002</a></td>
<td>
K
B
V
</td>
<td>DNA-binding transcriptional regulator, chromatin protein or antitoxin AbrBPrlF/Sso7c4, AbrB family</td>
</tr>
<tr>
<td>759</td>
<td>959</td>
<td><a href="/research/cog/cog/COG2005/">COG2005</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator ModE (molybdenum-dependent)</td>
</tr>
<tr>
<td>190</td>
<td>191</td>
<td><a href="/research/cog/cog/COG2012/">COG2012</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, subunit H, RpoH/RPB5</td>
</tr>
<tr>
<td>211</td>
<td>216</td>
<td><a href="/research/cog/cog/COG2093/">COG2093</a></td>
<td>
K
</td>
<td>RNA polymerase subunit RPABC4/transcription elongation factor Spt4</td>
</tr>
<tr>
<td>188</td>
<td>315</td>
<td><a href="/research/cog/cog/COG2101/">COG2101</a></td>
<td>
K
</td>
<td>TATA-box binding protein (TBP), component of TFIID and TFIIIB</td>
</tr>
<tr>
<td>1332</td>
<td>1348</td>
<td><a href="/research/cog/cog/COG2183/">COG2183</a></td>
<td>
K
</td>
<td>Transcriptional accessory protein Tex/SPT6</td>
</tr>
<tr>
<td>1177</td>
<td>4387</td>
<td><a href="/research/cog/cog/COG2186/">COG2186</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, FadR family</td>
</tr>
<tr>
<td>1320</td>
<td>4744</td>
<td><a href="/research/cog/cog/COG2188/">COG2188</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, GntR family</td>
</tr>
<tr>
<td>1858</td>
<td>17938</td>
<td><a href="/research/cog/cog/COG2197/">COG2197</a></td>
<td>
K
T
</td>
<td>DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains</td>
</tr>
<tr>
<td>1712</td>
<td>20612</td>
<td><a href="/research/cog/cog/COG2207/">COG2207</a></td>
<td>
K
</td>
<td>AraC-type DNA-binding domain and AraC-containing proteins</td>
</tr>
<tr>
<td>1025</td>
<td>3737</td>
<td><a href="/research/cog/cog/COG2208/">COG2208</a></td>
<td>
K
T
</td>
<td>Phosphoserine phosphatase RsbU, regulator of sigma subunit</td>
</tr>
<tr>
<td>217</td>
<td>264</td>
<td><a href="/research/cog/cog/COG2214/">COG2214</a></td>
<td>
K
</td>
<td>Curved DNA-binding protein CbpA, contains a DnaJ-like domain</td>
</tr>
<tr>
<td>752</td>
<td>871</td>
<td><a href="/research/cog/cog/COG2315/">COG2315</a></td>
<td>
K
</td>
<td>Predicted DNA-binding protein with double-wing structural motif, MmcQ/YjbR family</td>
</tr>
<tr>
<td>648</td>
<td>742</td>
<td><a href="/research/cog/cog/COG2344/">COG2344</a></td>
<td>
K
</td>
<td>NADH/NAD ratio-sensing transcriptional regulator Rex</td>
</tr>
<tr>
<td>627</td>
<td>975</td>
<td><a href="/research/cog/cog/COG2345/">COG2345</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, ArsR family</td>
</tr>
<tr>
<td>1465</td>
<td>3648</td>
<td><a href="/research/cog/cog/COG2378/">COG2378</a></td>
<td>
K
</td>
<td>Predicted DNA-binding transcriptional regulator YobV, contains HTH and WYL domains</td>
</tr>
<tr>
<td>657</td>
<td>1231</td>
<td><a href="/research/cog/cog/COG2390/">COG2390</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator LsrR, DeoR family</td>
</tr>
<tr>
<td>508</td>
<td>1714</td>
<td><a href="/research/cog/cog/COG2508/">COG2508</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, PucR/PutR family</td>
</tr>
<tr>
<td>184</td>
<td>277</td>
<td><a href="/research/cog/cog/COG2522/">COG2522</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains HTH domain</td>
</tr>
<tr>
<td>1086</td>
<td>1955</td>
<td><a href="/research/cog/cog/COG2524/">COG2524</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains C-terminal CBS domains</td>
</tr>
<tr>
<td>213</td>
<td>239</td>
<td><a href="/research/cog/cog/COG2732/">COG2732</a></td>
<td>
K
</td>
<td>Barstar, RNAse (barnase) inhibitor</td>
</tr>
<tr>
<td>391</td>
<td>393</td>
<td><a href="/research/cog/cog/COG2739/">COG2739</a></td>
<td>
K
</td>
<td>Predicted DNA-binding protein YlxM, UPF0122 family</td>
</tr>
<tr>
<td>523</td>
<td>541</td>
<td><a href="/research/cog/cog/COG2747/">COG2747</a></td>
<td>
K
N
</td>
<td>Negative regulator of flagellin synthesis (anti-sigma28 factor)</td>
</tr>
<tr>
<td>341</td>
<td>536</td>
<td><a href="/research/cog/cog/COG2771/">COG2771</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, CsgD family</td>
</tr>
<tr>
<td>752</td>
<td>1506</td>
<td><a href="/research/cog/cog/COG2865/">COG2865</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains HTH domain</td>
</tr>
<tr>
<td>448</td>
<td>461</td>
<td><a href="/research/cog/cog/COG2901/">COG2901</a></td>
<td>
K
</td>
<td>DNA-binding protein Fis (factor for inversion stimulation)</td>
</tr>
<tr>
<td>618</td>
<td>1315</td>
<td><a href="/research/cog/cog/COG2909/">COG2909</a></td>
<td>
K
</td>
<td>ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT</td>
</tr>
<tr>
<td>668</td>
<td>1127</td>
<td><a href="/research/cog/cog/COG2944/">COG2944</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator YiaG, XRE-type HTH domain</td>
</tr>
<tr>
<td>347</td>
<td>464</td>
<td><a href="/research/cog/cog/COG2964/">COG2964</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains</td>
</tr>
<tr>
<td>138</td>
<td>139</td>
<td><a href="/research/cog/cog/COG2973/">COG2973</a></td>
<td>
K
</td>
<td>Trp operon repressor</td>
</tr>
<tr>
<td>128</td>
<td>128</td>
<td><a href="/research/cog/cog/COG3060/">COG3060</a></td>
<td>
K
E
</td>
<td>Transcriptional regulator MetJ (met regulon)</td>
</tr>
<tr>
<td>455</td>
<td>482</td>
<td><a href="/research/cog/cog/COG3070/">COG3070</a></td>
<td>
K
</td>
<td>Transcriptional regulator of competence genes, TfoX/Sxy family</td>
</tr>
<tr>
<td>130</td>
<td>130</td>
<td><a href="/research/cog/cog/COG3112/">COG3112</a></td>
<td>
K
</td>
<td>YacL protein, interacts with RNA polymerase and NusG, UPF0231 family</td>
</tr>
<tr>
<td>170</td>
<td>172</td>
<td><a href="/research/cog/cog/COG3160/">COG3160</a></td>
<td>
K
</td>
<td>Regulator of sigma D</td>
</tr>
<tr>
<td>1182</td>
<td>2362</td>
<td><a href="/research/cog/cog/COG3177/">COG3177</a></td>
<td>
K
</td>
<td>Fic family protein</td>
</tr>
<tr>
<td>291</td>
<td>613</td>
<td><a href="/research/cog/cog/COG3226/">COG3226</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator YbjK</td>
</tr>
<tr>
<td>1066</td>
<td>3985</td>
<td><a href="/research/cog/cog/COG3279/">COG3279</a></td>
<td>
K
T
</td>
<td>DNA-binding response regulator, LytR/AlgR family</td>
</tr>
<tr>
<td>156</td>
<td>167</td>
<td><a href="/research/cog/cog/COG3283/">COG3283</a></td>
<td>
K
E
</td>
<td>Transcriptional regulator TyrR of aromatic amino acids metabolism</td>
</tr>
<tr>
<td>547</td>
<td>940</td>
<td><a href="/research/cog/cog/COG3284/">COG3284</a></td>
<td>
K
</td>
<td>Transcriptional regulator DhaR of acetoin/glycerol metabolism</td>
</tr>
<tr>
<td>242</td>
<td>421</td>
<td><a href="/research/cog/cog/COG3289/">COG3289</a></td>
<td>
K
</td>
<td>Stand-alone LytTR domain, transcriptional regulator</td>
</tr>
<tr>
<td>903</td>
<td>1682</td>
<td><a href="/research/cog/cog/COG3311/">COG3311</a></td>
<td>
K
X
</td>
<td>DNA-binding transcriptional regulator AlpA</td>
</tr>
<tr>
<td>319</td>
<td>443</td>
<td><a href="/research/cog/cog/COG3327/">COG3327</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator PaaX (phenylacetic acid degradation)</td>
</tr>
<tr>
<td>201</td>
<td>201</td>
<td><a href="/research/cog/cog/COG3343/">COG3343</a></td>
<td>
K
</td>
<td>DNA-directed RNA polymerase, delta subunit</td>
</tr>
<tr>
<td>177</td>
<td>430</td>
<td><a href="/research/cog/cog/COG3355/">COG3355</a></td>
<td>
K
N
</td>
<td>Transcriptional regulator of archaellar biosynthesis and archaeal biofilm formation AfbR</td>
</tr>
<tr>
<td>134</td>
<td>136</td>
<td><a href="/research/cog/cog/COG3357/">COG3357</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains HTH and Zn-ribbon domains</td>
</tr>
<tr>
<td>16</td>
<td>21</td>
<td><a href="/research/cog/cog/COG3373/">COG3373</a></td>
<td>
K
N
</td>
<td>Transcriptional regulator of archaellum operon</td>
</tr>
<tr>
<td>105</td>
<td>132</td>
<td><a href="/research/cog/cog/COG3388/">COG3388</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator</td>
</tr>
<tr>
<td>115</td>
<td>315</td>
<td><a href="/research/cog/cog/COG3398/">COG3398</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains two HTH domains</td>
</tr>
<tr>
<td>142</td>
<td>282</td>
<td><a href="/research/cog/cog/COG3423/">COG3423</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, lambda repressor-like DNA-binding domain</td>
</tr>
<tr>
<td>797</td>
<td>1788</td>
<td><a href="/research/cog/cog/COG3604/">COG3604</a></td>
<td>
K
T
</td>
<td>FhlA-type transcriptional regulator, contains GAF, AAA-type ATPase, and DNA-binding Fis domains</td>
</tr>
<tr>
<td>613</td>
<td>1176</td>
<td><a href="/research/cog/cog/COG3609/">COG3609</a></td>
<td>
K
</td>
<td>Transcriptional regulator, contains Arc/MetJ-type RHH (ribbon-helix-helix) DNA-binding domain</td>
</tr>
<tr>
<td>1126</td>
<td>1747</td>
<td><a href="/research/cog/cog/COG3620/">COG3620</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair)</td>
</tr>
<tr>
<td>487</td>
<td>1970</td>
<td><a href="/research/cog/cog/COG3629/">COG3629</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator DnrI/AfsR/EmbR, SARP family, contains BTAD domain</td>
</tr>
<tr>
<td>816</td>
<td>1384</td>
<td><a href="/research/cog/cog/COG3655/">COG3655</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, XRE family</td>
</tr>
<tr>
<td>815</td>
<td>1741</td>
<td><a href="/research/cog/cog/COG3682/">COG3682</a></td>
<td>
K
</td>
<td>Transcriptional regulator, CopY/TcrY family</td>
</tr>
<tr>
<td>848</td>
<td>905</td>
<td><a href="/research/cog/cog/COG3695/">COG3695</a></td>
<td>
K
</td>
<td>Alkylated DNA nucleotide flippase Atl1, participates in nucleotide excision repair, Ada-like DNA-binding domain</td>
</tr>
<tr>
<td>1234</td>
<td>5588</td>
<td><a href="/research/cog/cog/COG3706/">COG3706</a></td>
<td>
K
T
</td>
<td>Two-component response regulator, PleD family, consists of two REC domains and a diguanylate cyclase (GGDEF) domain</td>
</tr>
<tr>
<td>868</td>
<td>1390</td>
<td><a href="/research/cog/cog/COG3707/">COG3707</a></td>
<td>
K
T
</td>
<td>Two-component response regulator, AmiR/NasT family, consists of REC and RNA-binding antiterminator (ANTAR) domains</td>
</tr>
<tr>
<td>574</td>
<td>958</td>
<td><a href="/research/cog/cog/COG3708/">COG3708</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator YdeE, contains AraC-type DNA-binding domain</td>
</tr>
<tr>
<td>389</td>
<td>1114</td>
<td><a href="/research/cog/cog/COG3710/">COG3710</a></td>
<td>
K
</td>
<td>DNA-binding winged helix-turn-helix (wHTH) domain</td>
</tr>
<tr>
<td>379</td>
<td>1461</td>
<td><a href="/research/cog/cog/COG3711/">COG3711</a></td>
<td>
K
</td>
<td>Transcriptional antiterminator</td>
</tr>
<tr>
<td>83</td>
<td>92</td>
<td><a href="/research/cog/cog/COG3722/">COG3722</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator, MltR family</td>
</tr>
<tr>
<td>149</td>
<td>230</td>
<td><a href="/research/cog/cog/COG3801/">COG3801</a></td>
<td>
K
</td>
<td>Predicted DNA-binding protein, MmcQ/YjbR superfamily</td>
</tr>
<tr>
<td>291</td>
<td>291</td>
<td><a href="/research/cog/cog/COG3820/">COG3820</a></td>
<td>
K
</td>
<td>Cell cycle regulator TrcR, DUF1013 family</td>
</tr>
<tr>
<td>837</td>
<td>2918</td>
<td><a href="/research/cog/cog/COG3829/">COG3829</a></td>
<td>
K
T
</td>
<td>RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains</td>
</tr>
<tr>
<td>216</td>
<td>337</td>
<td><a href="/research/cog/cog/COG3831/">COG3831</a></td>
<td>
K
</td>
<td>WGR domain, predicted DNA-binding domain in MolR</td>
</tr>
<tr>
<td>485</td>
<td>862</td>
<td><a href="/research/cog/cog/COG3835/">COG3835</a></td>
<td>
K
T
</td>
<td>Sugar diacid utilization regulator CdaR</td>
</tr>
<tr>
<td>204</td>
<td>227</td>
<td><a href="/research/cog/cog/COG3877/">COG3877</a></td>
<td>
K
</td>
<td>Predicted DNA-binding transcriptional regulator with XRE-family HTH domain, DUF2089 family</td>
</tr>
<tr>
<td>27</td>
<td>28</td>
<td><a href="/research/cog/cog/COG3888/">COG3888</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator</td>
</tr>
<tr>
<td>162</td>
<td>194</td>
<td><a href="/research/cog/cog/COG3901/">COG3901</a></td>
<td>
K
</td>
<td>Transcriptional regulator NosR of nitric oxide reductase</td>
</tr>
<tr>
<td>266</td>
<td>359</td>
<td><a href="/research/cog/cog/COG3905/">COG3905</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains ribbon-helix-helix (RHH_1) domain</td>
</tr>
<tr>
<td>121</td>
<td>234</td>
<td><a href="/research/cog/cog/COG3933/">COG3933</a></td>
<td>
K
</td>
<td>Transcriptional regulator of LevR family, contains sigma54-interacting AAA domain, PTS regulation domain (PRD), and EIIA-type domain</td>
</tr>
<tr>
<td>185</td>
<td>255</td>
<td><a href="/research/cog/cog/COG3947/">COG3947</a></td>
<td>
K
T
</td>
<td>Two-component response regulator, SAPR family, consists of REC, wHTH and BTAD domains</td>
</tr>
<tr>
<td>39</td>
<td>40</td>
<td><a href="/research/cog/cog/COG4008/">COG4008</a></td>
<td>
K
</td>
<td>Predicted metal-binding transcription factor, methanogenesis marker domain 9</td>
</tr>
<tr>
<td>490</td>
<td>582</td>
<td><a href="/research/cog/cog/COG4109/">COG4109</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator containing CBS domains</td>
</tr>
<tr>
<td>237</td>
<td>309</td>
<td><a href="/research/cog/cog/COG4189/">COG4189</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, ArsR family</td>
</tr>
<tr>
<td>189</td>
<td>317</td>
<td><a href="/research/cog/cog/COG4190/">COG4190</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains HTH domain</td>
</tr>
<tr>
<td>115</td>
<td>142</td>
<td><a href="/research/cog/cog/COG4197/">COG4197</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator YdaS, prophage-encoded, Cro superfamily</td>
</tr>
<tr>
<td>227</td>
<td>227</td>
<td><a href="/research/cog/cog/COG4255/">COG4255</a></td>
<td>
K
</td>
<td>Regulator of pathogenicity factor RpfE</td>
</tr>
<tr>
<td>337</td>
<td>365</td>
<td><a href="/research/cog/cog/COG4256/">COG4256</a></td>
<td>
K
H
</td>
<td>RNA-binding regulator of hemin uptake HemP/HmuP</td>
</tr>
<tr>
<td>51</td>
<td>55</td>
<td><a href="/research/cog/cog/COG4344/">COG4344</a></td>
<td>
K
</td>
<td>Predicted transciptional regulator, contains DUF2250 domain</td>
</tr>
<tr>
<td>270</td>
<td>270</td>
<td><a href="/research/cog/cog/COG4463/">COG4463</a></td>
<td>
K
</td>
<td>Transcriptional regulator CtsR</td>
</tr>
<tr>
<td>255</td>
<td>273</td>
<td><a href="/research/cog/cog/COG4465/">COG4465</a></td>
<td>
K
</td>
<td>GTP-sensing pleiotropic transcriptional regulator CodY</td>
</tr>
<tr>
<td>103</td>
<td>169</td>
<td><a href="/research/cog/cog/COG4512/">COG4512</a></td>
<td>
K
T
</td>
<td>Accessory gene regulator protein AgrB</td>
</tr>
<tr>
<td>123</td>
<td>199</td>
<td><a href="/research/cog/cog/COG4533/">COG4533</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator SgrR of sgrS sRNA, contains a MarR-type HTH domain and a periplasmic-type solute-binding domain</td>
</tr>
<tr>
<td>511</td>
<td>800</td>
<td><a href="/research/cog/cog/COG4565/">COG4565</a></td>
<td>
K
T
</td>
<td>DNA-binding response regulator DpiB of citrate/malate metabolism</td>
</tr>
<tr>
<td>553</td>
<td>1539</td>
<td><a href="/research/cog/cog/COG4566/">COG4566</a></td>
<td>
K
T
</td>
<td>DNA-binding response regulator, FixJ family, consists of REC and HTH domains</td>
</tr>
<tr>
<td>494</td>
<td>559</td>
<td><a href="/research/cog/cog/COG4567/">COG4567</a></td>
<td>
K
T
</td>
<td>DNA-binding response regulator, ActR/RegA family, consists of REC and Fis-type HTH domains</td>
</tr>
<tr>
<td>136</td>
<td>138</td>
<td><a href="/research/cog/cog/COG4568/">COG4568</a></td>
<td>
K
</td>
<td>Transcriptional antiterminator Rof (Rho-off)</td>
</tr>
<tr>
<td>162</td>
<td>179</td>
<td><a href="/research/cog/cog/COG4578/">COG4578</a></td>
<td>
K
</td>
<td>DNA-binding transcriptional regulator of glucitol operon</td>
</tr>
<tr>
<td>128</td>
<td>133</td>
<td><a href="/research/cog/cog/COG4650/">COG4650</a></td>
<td>
K
T
</td>
<td>Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain</td>
</tr>
<tr>
<td>46</td>
<td>77</td>
<td><a href="/research/cog/cog/COG4738/">COG4738</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator</td>
</tr>
<tr>
<td>136</td>
<td>601</td>
<td><a href="/research/cog/cog/COG4742/">COG4742</a></td>
<td>
K
N
</td>
<td>Transcriptional regulator of archaellar expression ArnR</td>
</tr>
<tr>
<td>872</td>
<td>2493</td>
<td><a href="/research/cog/cog/COG4753/">COG4753</a></td>
<td>
K
T
</td>
<td>Two-component response regulator, YesN/AraC family, consists of REC and AraC-type DNA-binding domains</td>
</tr>
<tr>
<td>131</td>
<td>131</td>
<td><a href="/research/cog/cog/COG4776/">COG4776</a></td>
<td>
K
</td>
<td>Exoribonuclease II</td>
</tr>
<tr>
<td>40</td>
<td>42</td>
<td><a href="/research/cog/cog/COG4800/">COG4800</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator with an HTH domain</td>
</tr>
<tr>
<td>91</td>
<td>96</td>
<td><a href="/research/cog/cog/COG4815/">COG4815</a></td>
<td>
K
</td>
<td>DNA/RNA-binding protein MepB</td>
</tr>
<tr>
<td>106</td>
<td>106</td>
<td><a href="/research/cog/cog/COG4838/">COG4838</a></td>
<td>
K
</td>
<td>Fur protein antagonist Fpa/YlaN, UPF0358/DUF1507 family</td>
</tr>
<tr>
<td>43</td>
<td>43</td>
<td><a href="/research/cog/cog/COG4860/">COG4860</a></td>
<td>
K
</td>
<td>Predicted DNA-binding transcriptional regulator, ArsR family</td>
</tr>
<tr>
<td>208</td>
<td>273</td>
<td><a href="/research/cog/cog/COG4862/">COG4862</a></td>
<td>
K
T
N
</td>
<td>Negative regulator MecA of genetic competence, sporulation and motility</td>
</tr>
<tr>
<td>55</td>
<td>69</td>
<td><a href="/research/cog/cog/COG4871/">COG4871</a></td>
<td>
K
</td>
<td>Metal-binding trascriptional regulator, contains Fe-S cluster and ArsR family DNA binding domain</td>
</tr>
<tr>
<td>75</td>
<td>77</td>
<td><a href="/research/cog/cog/COG4876/">COG4876</a></td>
<td>
K
</td>
<td>DNA-binding prophage repressor, YdaT family</td>
</tr>
<tr>
<td>324</td>
<td>331</td>
<td><a href="/research/cog/cog/COG4877/">COG4877</a></td>
<td>
K
</td>
<td>Arc-like DNA-binding domain</td>
</tr>
<tr>
<td>42</td>
<td>42</td>
<td><a href="/research/cog/cog/COG4888/">COG4888</a></td>
<td>
K
</td>
<td>Transcription elongation factor Elf1, contains Zn-ribbon domain</td>
</tr>
<tr>
<td>83</td>
<td>132</td>
<td><a href="/research/cog/cog/COG4903/">COG4903</a></td>
<td>
K
</td>
<td>Competence transcription factor ComK</td>
</tr>
<tr>
<td>128</td>
<td>135</td>
<td><a href="/research/cog/cog/COG4933/">COG4933</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator, contains an HTH and PUA-like domains</td>
</tr>
<tr>
<td>481</td>
<td>1071</td>
<td><a href="/research/cog/cog/COG4941/">COG4941</a></td>
<td>
K
</td>
<td>Predicted RNA polymerase sigma factor, contains C-terminal TPR domain</td>
</tr>
<tr>
<td>251</td>
<td>535</td>
<td><a href="/research/cog/cog/COG4957/">COG4957</a></td>
<td>
K
</td>
<td>Predicted transcriptional regulator</td>
</tr>
<tr>
<td>1202</td>
<td>4311</td>
<td><a href="/research/cog/cog/COG4977/">COG4977</a></td>
<td>
K
</td>
<td>Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain</td>
</tr>
<tr>
<td>16</td>
<td>18</td>
<td><a href="/research/cog/cog/COG5108/">COG5108</a></td>
<td>
K
</td>
<td>Mitochondrial DNA-directed RNA polymerase</td>
</tr>
<tr>
<td>4</td>
<td>4</td>
<td><a href="/research/cog/cog/COG5164/">COG5164</a></td>
<td>
K
</td>
<td>Transcription elongation factor SPT5</td>
</tr>
<tr>
<td>23</td>
<td>24</td>
<td><a href="/research/cog/cog/COG5190/">COG5190</a></td>
<td>
K
</td>
<td>TFIIF-interacting CTD phosphatase, includes NLI-interacting factor</td>
</tr>
<tr>
<td>111</td>
<td>146</td>
<td><a href="/research/cog/cog/COG5304/">COG5304</a></td>
<td>
K
</td>
<td>Predicted DNA binding protein, CopG/RHH family</td>
</tr>
<tr>
<td>271</td>
<td>317</td>
<td><a href="/research/cog/cog/COG5352/">COG5352</a></td>
<td>
K
</td>
<td>Transcription factor GcrA interacting with sigma70</td>
</tr>
<tr>
<td>90</td>
<td>129</td>
<td><a href="/research/cog/cog/COG5419/">COG5419</a></td>
<td>
K
</td>
<td>Hexameric transcriptional regulator RovC, contains DUF2285 domain</td>
</tr>
<tr>
<td>188</td>
<td>209</td>
<td><a href="/research/cog/cog/COG5450/">COG5450</a></td>
<td>
K
</td>
<td>Transcription regulator of the Arc/MetJ class, contains ribbon-helix-helix (RHH) domain</td>
</tr>
<tr>
<td>129</td>
<td>129</td>
<td><a href="/research/cog/cog/COG5503/">COG5503</a></td>
<td>
K
V
</td>
<td>DNA-dependent RNA polymerase auxiliary subunit epsilon</td>
</tr>
<tr>
<td>100</td>
<td>136</td>
<td><a href="/research/cog/cog/COG5566/">COG5566</a></td>
<td>
K
X
</td>
<td>Transcriptional regulator, middle operon regulator (Mor) family</td>
</tr>
<tr>
<td>21</td>
<td>23</td>
<td><a href="/research/cog/cog/COG5625/">COG5625</a></td>
<td>
K
</td>
<td>Predicted DNA-binding transcriptional regulator, contains HTH domain</td>
</tr>
<tr>
<td>123</td>
<td>132</td>
<td><a href="/research/cog/cog/COG5631/">COG5631</a></td>
<td>
K
</td>
<td>Predicted transcription regulator, contains HTH domain, MarR family</td>
</tr>
<tr>
<td>534</td>
<td>743</td>
<td><a href="/research/cog/cog/COG5662/">COG5662</a></td>
<td>
K
</td>
<td>Transmembrane transcriptional regulator RsiW (anti-sigma-W factor)</td>
</tr>
<tr>
<td>12</td>
<td>12</td>
<td><a href="/research/cog/cog/COG5665/">COG5665</a></td>
<td>
K
</td>
<td>CCR4-NOT transcriptional regulation complex, NOT5 subunit</td>
</tr>
<tr>
<td>67</td>
<td>68</td>
<td><a href="/research/cog/cog/COG5794/">COG5794</a></td>
<td>
K
</td>
<td>RNA-binding protein Asl3888</td>
</tr>
<tr>
<td>234</td>
<td>234</td>
<td><a href="/research/cog/cog/COG5811/">COG5811</a></td>
<td>
K
D
</td>
<td>Sporulation sigma factor SigE (mother cell-specific, SpoIIGB)</td>
</tr>
<tr>
<td>224</td>
<td>225</td>
<td><a href="/research/cog/cog/COG5812/">COG5812</a></td>
<td>
K
D
</td>
<td>Sporulation sigma factor SigF (forespore-specific, SpoIIAC)</td>
</tr>
<tr>
<td>228</td>
<td>233</td>
<td><a href="/research/cog/cog/COG5813/">COG5813</a></td>
<td>
K
D
</td>
<td>Sporulation sigma factor SigG (forespore-specific, SpoIIIG)</td>
</tr>
<tr>
<td>221</td>
<td>242</td>
<td><a href="/research/cog/cog/COG5814/">COG5814</a></td>
<td>
K
D
</td>
<td>Sporulation sigma factor SigK (mother cell-specific, SpoIIIC/SpoIVCB)</td>
</tr>
<tr>
<td>233</td>
<td>233</td>
<td><a href="/research/cog/cog/COG5818/">COG5818</a></td>
<td>
K
D
O
</td>
<td>Stage II sporulation protein SpoIIGA (protease, processing of pro-sigma-E to active sigma-E)</td>
</tr>
<tr>
<td>227</td>
<td>236</td>
<td><a href="/research/cog/cog/COG5830/">COG5830</a></td>
<td>
K
D
</td>
<td>Stage III sporulation protein SpoIIID, transcriptional regulator of sigma-E- and sigma-K-dependent genes</td>
</tr>
<tr>
<td>266</td>
<td>600</td>
<td><a href="/research/cog/cog/COG5845/">COG5845</a></td>
<td>
K
D
</td>
<td>Stage V sporulation protein SpoVT, regulator of stationary/sporulation gene expression</td>
</tr>
<tr>
<td>98</td>
<td>191</td>
<td><a href="/research/cog/cog/COG5850/">COG5850</a></td>
<td>
K
D
</td>
<td>Prespore-specific transcriptional regulator RsfA</td>
</tr>
<tr>
<td>110</td>
<td>110</td>
<td><a href="/research/cog/cog/COG5865/">COG5865</a></td>
<td>
K
D
</td>
<td>Forespore-specific anti-sigma-G factor CsfB/Gin</td>
</tr>
<tr>
<td>40</td>
<td>40</td>
<td><a href="/research/cog/cog/COG5870/">COG5870</a></td>
<td>
K
D
</td>
<td>Uncharacterized sporulation protein YbaK, contains DUF2521 domain (not related to E. coli deacylase YbaK, COG2606)</td>
</tr>
<tr>
<td>966</td>
<td>2208</td>
<td><a href="/research/cog/cog/COG5905/">COG5905</a></td>
<td>
K
D
</td>
<td>Spore transcriptional regulator GerE (stand-alone HTH domain)</td>
</tr>
<tr>
<td>59</td>
<td>88</td>
<td><a href="/research/cog/cog/COG6084/">COG6084</a></td>
<td>
K
N
</td>
<td>Regulator of haloarchaeal motility, adhesion and cell morphology</td>
</tr>
<tr>
<td>88</td>
<td>105</td>
<td><a href="/research/cog/cog/COG6095/">COG6095</a></td>
<td>
K
T
</td>
<td>YcbB domain, DNA-binding domain in GlnL-type response regulators</td>
</tr>
<tr>
<td>15</td>
<td>20</td>
<td><a href="/research/cog/cog/COG6096/">COG6096</a></td>
<td>
K
T
</td>
<td>BetR domain, DNA-binding domain in betaproteobacterial response regulators</td>
</tr>
<tr>
<td>24</td>
<td>24</td>
<td><a href="/research/cog/cog/COG6136/">COG6136</a></td>
<td>
K
</td>
<td>Archaeal DNA-directed RNA polymerase subunit 8, Rpo8/RpbG</td>
</tr>
<tr>
<td>8</td>
<td>8</td>
<td><a href="/research/cog/cog/COG6137/">COG6137</a></td>
<td>
K
</td>
<td>Archaeal DNA-directed RNA polymerase subunit 13, Rpo13/RpbQ</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</section>
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