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<span class="headername">Database of Clusters of Orthologous Genes (COGs)</span>
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J - Translation, ribosomal structure and biogenesis</a>
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D - Cell cycle control, cell division, chromosome partitioning</a>
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Y - Nuclear structure</a>
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V - Defense mechanisms</a>
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C - Energy production and conversion</a>
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<h1>D<span style='font-weight: 100'> - Cell cycle control, cell division, chromosome partitioning</span></h1>
<div style="float: right; clear: both;margin-top: -53px;">
<a class="usa-button" href="#" onclick="download_table_as_tsv('cog_result_table');">Download</a>
</div>
<h2>Stats</h2>
<div style="width: 60%">
<div class="ui-ncbigrid-outer-div organism_cog_table">
<div class="ui-ncbigrid-inner-div">
<table data-jig="ncbigrid">
<thead>
<tr>
<th>COG<br>definitions</th>
<th>Organims</th>
<th>Proteins</th>
<th>Median Protein<br>Length</th>
<th>Genes</th>
</tr>
</thead>
<tbody>
<tr>
<td>195</td>
<td>2,291</td>
<td>133,776</td>
<td>337.0</td>
<td>193</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="ui-ncbigrid-outer-div" style="font-size: 80%;">
<div class="ui-ncbigrid-inner-div">
<table id="cog_result_table" data-jig="ncbigrid">
<thead>
<tr>
<th>Organism</th>
<th>Protein</th>
<th>COG</th>
<th>Cat</th>
<th>Annotation</th>
</tr>
</thead>
<tbody>
<tr>
<td>2140</td>
<td>2448</td>
<td><a href="/research/cog/cog/COG0206/">COG0206</a></td>
<td>
D
</td>
<td>Cell division GTPase FtsZ</td>
</tr>
<tr>
<td>1684</td>
<td>1720</td>
<td><a href="/research/cog/cog/COG0218/">COG0218</a></td>
<td>
D
</td>
<td>GTP-binding protein EngB required for normal cell division</td>
</tr>
<tr>
<td>1667</td>
<td>2244</td>
<td><a href="/research/cog/cog/COG0239/">COG0239</a></td>
<td>
D
P
</td>
<td>Fluoride ion exporter CrcB/FEX, affects chromosome condensation</td>
</tr>
<tr>
<td>1055</td>
<td>1639</td>
<td><a href="/research/cog/cog/COG0455/">COG0455</a></td>
<td>
D
N
</td>
<td>MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase</td>
</tr>
<tr>
<td>1254</td>
<td>2738</td>
<td><a href="/research/cog/cog/COG0464/">COG0464</a></td>
<td>
D
T
M
</td>
<td>AAA+-type ATPase, SpoVK/Ycf46/Vps4 family</td>
</tr>
<tr>
<td>2111</td>
<td>5318</td>
<td><a href="/research/cog/cog/COG0489/">COG0489</a></td>
<td>
D
</td>
<td>Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family</td>
</tr>
<tr>
<td>1548</td>
<td>4743</td>
<td><a href="/research/cog/cog/COG0535/">COG0535</a></td>
<td>
D
H
</td>
<td>Radical SAM superfamily maturase, SkfB/NifB/PqqE family</td>
</tr>
<tr>
<td>2042</td>
<td>2043</td>
<td><a href="/research/cog/cog/COG0536/">COG0536</a></td>
<td>
L
D
</td>
<td>GTPase involved in cell partioning and DNA repair</td>
</tr>
<tr>
<td>2023</td>
<td>5041</td>
<td><a href="/research/cog/cog/COG0768/">COG0768</a></td>
<td>
D
M
</td>
<td>Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2)</td>
</tr>
<tr>
<td>2026</td>
<td>4359</td>
<td><a href="/research/cog/cog/COG0772/">COG0772</a></td>
<td>
D
</td>
<td>Peptodoglycan polymerase FtsW/RodA/SpoVE</td>
</tr>
<tr>
<td>1578</td>
<td>1717</td>
<td><a href="/research/cog/cog/COG0849/">COG0849</a></td>
<td>
D
</td>
<td>Cell division ATPase FtsA</td>
</tr>
<tr>
<td>871</td>
<td>893</td>
<td><a href="/research/cog/cog/COG0850/">COG0850</a></td>
<td>
D
</td>
<td>Septum site-determining protein MinC</td>
</tr>
<tr>
<td>731</td>
<td>739</td>
<td><a href="/research/cog/cog/COG0851/">COG0851</a></td>
<td>
D
</td>
<td>Septum formation topological specificity factor MinE</td>
</tr>
<tr>
<td>1669</td>
<td>2229</td>
<td><a href="/research/cog/cog/COG1077/">COG1077</a></td>
<td>
D
Z
</td>
<td>Cell shape-determining ATPase MreB, actin-like superfamily</td>
</tr>
<tr>
<td>2043</td>
<td>6215</td>
<td><a href="/research/cog/cog/COG1192/">COG1192</a></td>
<td>
D
N
</td>
<td>ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ</td>
</tr>
<tr>
<td>2029</td>
<td>4908</td>
<td><a href="/research/cog/cog/COG1196/">COG1196</a></td>
<td>
D
</td>
<td>Chromosome segregation ATPase Smc</td>
</tr>
<tr>
<td>702</td>
<td>809</td>
<td><a href="/research/cog/cog/COG1300/">COG1300</a></td>
<td>
D
</td>
<td>Stage II sporulation protein SpoIIM, component of the engulfment complex</td>
</tr>
<tr>
<td>1332</td>
<td>1598</td>
<td><a href="/research/cog/cog/COG1426/">COG1426</a></td>
<td>
D
</td>
<td>Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains</td>
</tr>
<tr>
<td>1989</td>
<td>4360</td>
<td><a href="/research/cog/cog/COG1475/">COG1475</a></td>
<td>
D
</td>
<td>Chromosome segregation protein Spo0J, contains ParB-like CTPase domain</td>
</tr>
<tr>
<td>810</td>
<td>885</td>
<td><a href="/research/cog/cog/COG1485/">COG1485</a></td>
<td>
D
</td>
<td>Cell division protein ZapE (Z ring-associated ATPase), AFG1 superfamily</td>
</tr>
<tr>
<td>1770</td>
<td>1771</td>
<td><a href="/research/cog/cog/COG1589/">COG1589</a></td>
<td>
D
</td>
<td>Cell division septal protein FtsQ</td>
</tr>
<tr>
<td>544</td>
<td>1053</td>
<td><a href="/research/cog/cog/COG1649/">COG1649</a></td>
<td>
D
</td>
<td>Divisome-localized peptidoglycan glycosyl hydrolase DigH/YddW </td>
</tr>
<tr>
<td>1962</td>
<td>3162</td>
<td><a href="/research/cog/cog/COG1674/">COG1674</a></td>
<td>
D
</td>
<td>DNA segregation ATPase FtsK/SpoIIIE or related protein</td>
</tr>
<tr>
<td>1325</td>
<td>2505</td>
<td><a href="/research/cog/cog/COG1729/">COG1729</a></td>
<td>
D
</td>
<td>Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction</td>
</tr>
<tr>
<td>1661</td>
<td>1667</td>
<td><a href="/research/cog/cog/COG1792/">COG1792</a></td>
<td>
D
Z
</td>
<td>Cell shape-determining protein MreC</td>
</tr>
<tr>
<td>693</td>
<td>760</td>
<td><a href="/research/cog/cog/COG1799/">COG1799</a></td>
<td>
D
</td>
<td>Cell division protein SepF/YlmF, interacts with FtsZ</td>
</tr>
<tr>
<td>361</td>
<td>429</td>
<td><a href="/research/cog/cog/COG2088/">COG2088</a></td>
<td>
D
</td>
<td>DNA-binding protein SpoVG, cell septation regulator</td>
</tr>
<tr>
<td>1173</td>
<td>2497</td>
<td><a href="/research/cog/cog/COG2132/">COG2132</a></td>
<td>
D
M
P
</td>
<td>Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)</td>
</tr>
<tr>
<td>1611</td>
<td>1673</td>
<td><a href="/research/cog/cog/COG2177/">COG2177</a></td>
<td>
D
</td>
<td>Cell division protein FtsX</td>
</tr>
<tr>
<td>1060</td>
<td>2014</td>
<td><a href="/research/cog/cog/COG2340/">COG2340</a></td>
<td>
D
R
</td>
<td>Spore germination protein YkwD and related proteins with CAP (CSP/antigen 5/PR1) domain</td>
</tr>
<tr>
<td>575</td>
<td>944</td>
<td><a href="/research/cog/cog/COG2385/">COG2385</a></td>
<td>
D
M
</td>
<td>Sporulation protein SpoIID (lytic transglycosylase)</td>
</tr>
<tr>
<td>149</td>
<td>150</td>
<td><a href="/research/cog/cog/COG2450/">COG2450</a></td>
<td>
D
</td>
<td>Predicted archaeal cell division protein, SepF family</td>
</tr>
<tr>
<td>572</td>
<td>587</td>
<td><a href="/research/cog/cog/COG2719/">COG2719</a></td>
<td>
D
</td>
<td>Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation (function unknown)</td>
</tr>
<tr>
<td>1694</td>
<td>5757</td>
<td><a href="/research/cog/cog/COG2755/">COG2755</a></td>
<td>
D
I
</td>
<td>Lysophospholipase L1 or related esterase. Includes spore coat protein LipC/YcsK</td>
</tr>
<tr>
<td>414</td>
<td>432</td>
<td><a href="/research/cog/cog/COG2848/">COG2848</a></td>
<td>
D
</td>
<td>Uncharacterized conserved protein, UPF0210 family</td>
</tr>
<tr>
<td>1576</td>
<td>1618</td>
<td><a href="/research/cog/cog/COG2884/">COG2884</a></td>
<td>
D
</td>
<td>Cell division ATPase FtsE</td>
</tr>
<tr>
<td>901</td>
<td>921</td>
<td><a href="/research/cog/cog/COG2894/">COG2894</a></td>
<td>
D
</td>
<td>Septum site-determining ATPase MinD</td>
</tr>
<tr>
<td>667</td>
<td>684</td>
<td><a href="/research/cog/cog/COG2917/">COG2917</a></td>
<td>
D
</td>
<td>Intracellular septation protein A</td>
</tr>
<tr>
<td>1224</td>
<td>1234</td>
<td><a href="/research/cog/cog/COG2919/">COG2919</a></td>
<td>
D
</td>
<td>Cell division protein FtsB</td>
</tr>
<tr>
<td>105</td>
<td>105</td>
<td><a href="/research/cog/cog/COG3006/">COG3006</a></td>
<td>
D
</td>
<td>Chromosome condensin MukBEF, kleisin-like MukF subunit</td>
</tr>
<tr>
<td>1007</td>
<td>1014</td>
<td><a href="/research/cog/cog/COG3027/">COG3027</a></td>
<td>
D
</td>
<td>Cell division protein ZapA, inhibits GTPase activity of FtsZ</td>
</tr>
<tr>
<td>238</td>
<td>315</td>
<td><a href="/research/cog/cog/COG3061/">COG3061</a></td>
<td>
D
</td>
<td>Cell division protein YtfB/OapA (opacity-associated protein A)</td>
</tr>
<tr>
<td>186</td>
<td>189</td>
<td><a href="/research/cog/cog/COG3074/">COG3074</a></td>
<td>
D
</td>
<td>Cell division protein ZapB, interacts with FtsZ</td>
</tr>
<tr>
<td>858</td>
<td>1174</td>
<td><a href="/research/cog/cog/COG3087/">COG3087</a></td>
<td>
D
</td>
<td>Cell division protein FtsN</td>
</tr>
<tr>
<td>102</td>
<td>102</td>
<td><a href="/research/cog/cog/COG3095/">COG3095</a></td>
<td>
D
</td>
<td>Chromosome condensin MukBEF, MukE localization factor</td>
</tr>
<tr>
<td>111</td>
<td>116</td>
<td><a href="/research/cog/cog/COG3096/">COG3096</a></td>
<td>
D
</td>
<td>Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB</td>
</tr>
<tr>
<td>211</td>
<td>211</td>
<td><a href="/research/cog/cog/COG3105/">COG3105</a></td>
<td>
D
</td>
<td>Membrane-anchored cell division protein YhcB, DUF1043 family</td>
</tr>
<tr>
<td>414</td>
<td>421</td>
<td><a href="/research/cog/cog/COG3115/">COG3115</a></td>
<td>
D
</td>
<td>Cell division protein ZipA, interacts with FtsZ</td>
</tr>
<tr>
<td>530</td>
<td>530</td>
<td><a href="/research/cog/cog/COG3116/">COG3116</a></td>
<td>
D
</td>
<td>Cell division protein FtsL, interacts with FtsB and FtsQ</td>
</tr>
<tr>
<td>648</td>
<td>784</td>
<td><a href="/research/cog/cog/COG3147/">COG3147</a></td>
<td>
D
</td>
<td>Cell division protein DedD (periplasmic protein involved in septation)</td>
</tr>
<tr>
<td>408</td>
<td>504</td>
<td><a href="/research/cog/cog/COG3266/">COG3266</a></td>
<td>
D
</td>
<td>Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain</td>
</tr>
<tr>
<td>331</td>
<td>500</td>
<td><a href="/research/cog/cog/COG3314/">COG3314</a></td>
<td>
D
E
</td>
<td>Spore dipicolinate transporter SpoVV/YjiH/YlbJ, contains nucleoside recognition GATE domain</td>
</tr>
<tr>
<td>581</td>
<td>785</td>
<td><a href="/research/cog/cog/COG3599/">COG3599</a></td>
<td>
D
</td>
<td>Cell division septum initiation protein DivIVA, interacts with FtsZ and MinD</td>
</tr>
<tr>
<td>228</td>
<td>273</td>
<td><a href="/research/cog/cog/COG3660/">COG3660</a></td>
<td>
D
</td>
<td>Mitochondrial fission protein ELM1</td>
</tr>
<tr>
<td>515</td>
<td>1028</td>
<td><a href="/research/cog/cog/COG3773/">COG3773</a></td>
<td>
D
M
</td>
<td>Cell wall hydrolase CwlJ, involved in spore germination</td>
</tr>
<tr>
<td>222</td>
<td>226</td>
<td><a href="/research/cog/cog/COG3827/">COG3827</a></td>
<td>
D
</td>
<td>Cell pole-organizing protein PopZ</td>
</tr>
<tr>
<td>342</td>
<td>350</td>
<td><a href="/research/cog/cog/COG3854/">COG3854</a></td>
<td>
D
</td>
<td>Stage III sporulation protein SpoIIIAA</td>
</tr>
<tr>
<td>453</td>
<td>884</td>
<td><a href="/research/cog/cog/COG3858/">COG3858</a></td>
<td>
D
</td>
<td>Spore cortex hydrolase SleL/YaaH, N-acetylglucosaminidase of GH18 family</td>
</tr>
<tr>
<td>273</td>
<td>310</td>
<td><a href="/research/cog/cog/COG3874/">COG3874</a></td>
<td>
D
</td>
<td>Spore protein YtfJ/GerW, could be involved in germination</td>
</tr>
<tr>
<td>151</td>
<td>241</td>
<td><a href="/research/cog/cog/COG4326/">COG4326</a></td>
<td>
D
</td>
<td>Stage 0 sporulation-control protein Spo0M</td>
</tr>
<tr>
<td>166</td>
<td>169</td>
<td><a href="/research/cog/cog/COG4477/">COG4477</a></td>
<td>
D
</td>
<td>Septation ring formation regulator EzrA</td>
</tr>
<tr>
<td>338</td>
<td>339</td>
<td><a href="/research/cog/cog/COG4582/">COG4582</a></td>
<td>
D
</td>
<td>Cell division protein ZapD, interacts with FtsZ</td>
</tr>
<tr>
<td>366</td>
<td>682</td>
<td><a href="/research/cog/cog/COG4641/">COG4641</a></td>
<td>
D
</td>
<td>Spore maturation protein CgeB</td>
</tr>
<tr>
<td>373</td>
<td>372</td>
<td><a href="/research/cog/cog/COG4839/">COG4839</a></td>
<td>
D
</td>
<td>Cell division protein FtsL, bacillar variant</td>
</tr>
<tr>
<td>1359</td>
<td>1793</td>
<td><a href="/research/cog/cog/COG4942/">COG4942</a></td>
<td>
D
</td>
<td>Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB</td>
</tr>
<tr>
<td>97</td>
<td>235</td>
<td><a href="/research/cog/cog/COG5023/">COG5023</a></td>
<td>
D
</td>
<td>Cell shape-controlling protein CetZ, FtsZ-like GTPase</td>
</tr>
<tr>
<td>316</td>
<td>1030</td>
<td><a href="/research/cog/cog/COG5184/">COG5184</a></td>
<td>
D
Z
</td>
<td>Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins</td>
</tr>
<tr>
<td>26</td>
<td>31</td>
<td><a href="/research/cog/cog/COG5185/">COG5185</a></td>
<td>
D
</td>
<td>Chromosome segregation protein NDC80, interacts with SMC proteins</td>
</tr>
<tr>
<td>210</td>
<td>316</td>
<td><a href="/research/cog/cog/COG5279/">COG5279</a></td>
<td>
D
</td>
<td>Cytokinesis protein 3, contains TGc (transglutaminase/protease-like) domain</td>
</tr>
<tr>
<td>360</td>
<td>447</td>
<td><a href="/research/cog/cog/COG5401/">COG5401</a></td>
<td>
D
</td>
<td>Spore germination protein GerM</td>
</tr>
<tr>
<td>136</td>
<td>139</td>
<td><a href="/research/cog/cog/COG5404/">COG5404</a></td>
<td>
D
</td>
<td>Cell division inhibitor SulA, prevents FtsZ ring assembly</td>
</tr>
<tr>
<td>241</td>
<td>241</td>
<td><a href="/research/cog/cog/COG5462/">COG5462</a></td>
<td>
D
</td>
<td>Cell division protein FtsL, alphaproteobacterial variant</td>
</tr>
<tr>
<td>39</td>
<td>109</td>
<td><a href="/research/cog/cog/COG5491/">COG5491</a></td>
<td>
D
</td>
<td>Archaeal cell division protein CdvB, Snf7/Vps24/ESCRT-III family</td>
</tr>
<tr>
<td>242</td>
<td>277</td>
<td><a href="/research/cog/cog/COG5801/">COG5801</a></td>
<td>
D
T
</td>
<td>Stage 0 sporulation initiation regulator Spo0A (response regulator, REC-HTH domains)</td>
</tr>
<tr>
<td>99</td>
<td>99</td>
<td><a href="/research/cog/cog/COG5802/">COG5802</a></td>
<td>
D
T
</td>
<td>Stage 0 sporulation initiation phosphotransferase Spo0B</td>
</tr>
<tr>
<td>161</td>
<td>211</td>
<td><a href="/research/cog/cog/COG5803/">COG5803</a></td>
<td>
D
T
</td>
<td>Stage 0 sporulation initiation response regulator Spo0F</td>
</tr>
<tr>
<td>151</td>
<td>436</td>
<td><a href="/research/cog/cog/COG5804/">COG5804</a></td>
<td>
D
T
</td>
<td>Stage 0 sporulation regulatory phosphatase Spo0E</td>
</tr>
<tr>
<td>42</td>
<td>58</td>
<td><a href="/research/cog/cog/COG5805/">COG5805</a></td>
<td>
D
T
</td>
<td>Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ)</td>
</tr>
<tr>
<td>47</td>
<td>114</td>
<td><a href="/research/cog/cog/COG5806/">COG5806</a></td>
<td>
D
T
</td>
<td>Sporulation sensor histidine kinase B</td>
</tr>
<tr>
<td>20</td>
<td>20</td>
<td><a href="/research/cog/cog/COG5807/">COG5807</a></td>
<td>
D
T
</td>
<td>Sporulation sensor histidine kinase C</td>
</tr>
<tr>
<td>30</td>
<td>37</td>
<td><a href="/research/cog/cog/COG5808/">COG5808</a></td>
<td>
D
T
</td>
<td>Sporulation sensor histidine kinase D</td>
</tr>
<tr>
<td>1006</td>
<td>3435</td>
<td><a href="/research/cog/cog/COG5809/">COG5809</a></td>
<td>
D
T
</td>
<td>Sporulation sensor histidine kinase E</td>
</tr>
<tr>
<td>83</td>
<td>83</td>
<td><a href="/research/cog/cog/COG5810/">COG5810</a></td>
<td>
D
T
</td>
<td>Sporulation protein KbaA, activator of histidine kinase KinB</td>
</tr>
<tr>
<td>234</td>
<td>234</td>
<td><a href="/research/cog/cog/COG5811/">COG5811</a></td>
<td>
K
D
</td>
<td>Sporulation sigma factor SigE (mother cell-specific, SpoIIGB)</td>
</tr>
<tr>
<td>224</td>
<td>225</td>
<td><a href="/research/cog/cog/COG5812/">COG5812</a></td>
<td>
K
D
</td>
<td>Sporulation sigma factor SigF (forespore-specific, SpoIIAC)</td>
</tr>
<tr>
<td>228</td>
<td>233</td>
<td><a href="/research/cog/cog/COG5813/">COG5813</a></td>
<td>
K
D
</td>
<td>Sporulation sigma factor SigG (forespore-specific, SpoIIIG)</td>
</tr>
<tr>
<td>221</td>
<td>242</td>
<td><a href="/research/cog/cog/COG5814/">COG5814</a></td>
<td>
K
D
</td>
<td>Sporulation sigma factor SigK (mother cell-specific, SpoIIIC/SpoIVCB)</td>
</tr>
<tr>
<td>888</td>
<td>1775</td>
<td><a href="/research/cog/cog/COG5815/">COG5815</a></td>
<td>
D
T
</td>
<td>Stage II sporulation protein SpoIIAA (anti-anti-sigma F factor), STAS domain</td>
</tr>
<tr>
<td>116</td>
<td>120</td>
<td><a href="/research/cog/cog/COG5816/">COG5816</a></td>
<td>
D
</td>
<td>Stage II sporulation protein SpoIIB (spatial and temporal regulation of the dissolution of septal peptidoglycan during engulfment)</td>
</tr>
<tr>
<td>382</td>
<td>496</td>
<td><a href="/research/cog/cog/COG5817/">COG5817</a></td>
<td>
D
</td>
<td>Stage II sporulation protein SpoIIE/SpoIIH (serine phosphatase - sigma-F activation)</td>
</tr>
<tr>
<td>233</td>
<td>233</td>
<td><a href="/research/cog/cog/COG5818/">COG5818</a></td>
<td>
K
D
O
</td>
<td>Stage II sporulation protein SpoIIGA (protease, processing of pro-sigma-E to active sigma-E)</td>
</tr>
<tr>
<td>233</td>
<td>328</td>
<td><a href="/research/cog/cog/COG5819/">COG5819</a></td>
<td>
D
</td>
<td>Stage II sporulation protein SpoIIP, required for dissolution of the septal cell wall</td>
</tr>
<tr>
<td>99</td>
<td>100</td>
<td><a href="/research/cog/cog/COG5820/">COG5820</a></td>
<td>
D
</td>
<td>Stage II sporulation protein SpoIIQ, required for engulfement</td>
</tr>
<tr>
<td>1226</td>
<td>2311</td>
<td><a href="/research/cog/cog/COG5821/">COG5821</a></td>
<td>
D
</td>
<td>Stage II sporulation protein SpoIIQ, clostridial version, metallopeptidase M23 family</td>
</tr>
<tr>
<td>222</td>
<td>227</td>
<td><a href="/research/cog/cog/COG5822/">COG5822</a></td>
<td>
D
</td>
<td>Stage II sporulation protein SpoIIR, required for processing of pro-sigma-E</td>
</tr>
<tr>
<td>213</td>
<td>213</td>
<td><a href="/research/cog/cog/COG5823/">COG5823</a></td>
<td>
D
</td>
<td>Stage III sporulation protein SpoIIIAB, component of the engulfment complex</td>
</tr>
<tr>
<td>225</td>
<td>226</td>
<td><a href="/research/cog/cog/COG5824/">COG5824</a></td>
<td>
D
</td>
<td>Stage III sporulation protein SpoIIIAC, component of the engulfment complex</td>
</tr>
<tr>
<td>219</td>
<td>219</td>
<td><a href="/research/cog/cog/COG5825/">COG5825</a></td>
<td>
D
</td>
<td>Stage III sporulation protein SpoIIIAD, component of the engulfment complex</td>
</tr>
<tr>
<td>226</td>
<td>227</td>
<td><a href="/research/cog/cog/COG5826/">COG5826</a></td>
<td>
D
</td>
<td>Stage III sporulation protein SpoIIIAE, component of the engulfment complex</td>
</tr>
<tr>
<td>204</td>
<td>204</td>
<td><a href="/research/cog/cog/COG5827/">COG5827</a></td>
<td>
D
</td>
<td>Stage III sporulation protein SpoIIIAF, component of the engulfment complex</td>
</tr>
<tr>
<td>227</td>
<td>227</td>
<td><a href="/research/cog/cog/COG5828/">COG5828</a></td>
<td>
D
</td>
<td>Stage III sporulation protein SpoIIIAG, component of the engulfment complex</td>
</tr>
<tr>
<td>239</td>
<td>239</td>
<td><a href="/research/cog/cog/COG5829/">COG5829</a></td>
<td>
D
</td>
<td>Stage III sporulation protein SpoIIIAH, component of the engulfment complex</td>
</tr>
<tr>
<td>227</td>
<td>236</td>
<td><a href="/research/cog/cog/COG5830/">COG5830</a></td>
<td>
K
D
</td>
<td>Stage III sporulation protein SpoIIID, transcriptional regulator of sigma-E- and sigma-K-dependent genes</td>
</tr>
<tr>
<td>234</td>
<td>237</td>
<td><a href="/research/cog/cog/COG5831/">COG5831</a></td>
<td>
D
</td>
<td>Stage IV sporulation protein SpoIVA, required for spore cortex formation and coat assembly</td>
</tr>
<tr>
<td>457</td>
<td>523</td>
<td><a href="/research/cog/cog/COG5832/">COG5832</a></td>
<td>
D
O
</td>
<td>Stage IV sporulation protein SpoIVB, serine protease, degrades SpoIIQ, SpoIVFA</td>
</tr>
<tr>
<td>136</td>
<td>137</td>
<td><a href="/research/cog/cog/COG5833/">COG5833</a></td>
<td>
D
</td>
<td>Stage IV sporulation protein SpoIVFA, regulates SpoIVFB</td>
</tr>
<tr>
<td>104</td>
<td>104</td>
<td><a href="/research/cog/cog/COG5834/">COG5834</a></td>
<td>
D
E
</td>
<td>Stage V sporulation protein SpoVAA, subunit of dipicolinate uptake complex</td>
</tr>
<tr>
<td>103</td>
<td>103</td>
<td><a href="/research/cog/cog/COG5835/">COG5835</a></td>
<td>
D
E
</td>
<td>Stage V sporulation protein SpoVAB, subunit of dipicolinate uptake complex</td>
</tr>
<tr>
<td>237</td>
<td>276</td>
<td><a href="/research/cog/cog/COG5836/">COG5836</a></td>
<td>
D
E
</td>
<td>Stage V sporulation protein SpoVAC, subunit of dipicolinate uptake complex</td>
</tr>
<tr>
<td>234</td>
<td>275</td>
<td><a href="/research/cog/cog/COG5837/">COG5837</a></td>
<td>
D
E
</td>
<td>Stage V sporulation protein SpoVAD, subunit of dipicolinate uptake complex</td>
</tr>
<tr>
<td>80</td>
<td>80</td>
<td><a href="/research/cog/cog/COG5838/">COG5838</a></td>
<td>
D
</td>
<td>Stage V sporulation protein SpoVAEA, mutants lead to the production of immature spores</td>
</tr>
<tr>
<td>236</td>
<td>271</td>
<td><a href="/research/cog/cog/COG5839/">COG5839</a></td>
<td>
D
E
</td>
<td>Stage V sporulation protein SpoVAEB, subunit of dipicolinate uptake complex</td>
</tr>
<tr>
<td>160</td>
<td>205</td>
<td><a href="/research/cog/cog/COG5840/">COG5840</a></td>
<td>
D
E
</td>
<td>Stage V sporulation protein SpoVAF, subunit of dipicolinate uptake complex, GerA superfamily</td>
</tr>
<tr>
<td>561</td>
<td>1022</td>
<td><a href="/research/cog/cog/COG5841/">COG5841</a></td>
<td>
D
</td>
<td>Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis</td>
</tr>
<tr>
<td>184</td>
<td>190</td>
<td><a href="/research/cog/cog/COG5842/">COG5842</a></td>
<td>
D
E
</td>
<td>Dipicolinate synthase subunit A (sporulation protein SpoVFA)</td>
</tr>
<tr>
<td>187</td>
<td>191</td>
<td><a href="/research/cog/cog/COG5843/">COG5843</a></td>
<td>
D
E
</td>
<td>Dipicolinate synthase subunit B (sporulation protein SpoVFB)</td>
</tr>
<tr>
<td>70</td>
<td>70</td>
<td><a href="/research/cog/cog/COG5844/">COG5844</a></td>
<td>
D
</td>
<td>Stage V sporulation protein SpoVM, required for spore cortex and coat synthesis</td>
</tr>
<tr>
<td>266</td>
<td>600</td>
<td><a href="/research/cog/cog/COG5845/">COG5845</a></td>
<td>
K
D
</td>
<td>Stage V sporulation protein SpoVT, regulator of stationary/sporulation gene expression</td>
</tr>
<tr>
<td>482</td>
<td>583</td>
<td><a href="/research/cog/cog/COG5846/">COG5846</a></td>
<td>
D
</td>
<td>Stage VI sporulation protein SpoVID (LysM domain), required for assembly of the spore coat</td>
</tr>
<tr>
<td>76</td>
<td>88</td>
<td><a href="/research/cog/cog/COG5847/">COG5847</a></td>
<td>
D
</td>
<td>Stage VI sporulation protein SpoVIF, required for heat resistance</td>
</tr>
<tr>
<td>165</td>
<td>168</td>
<td><a href="/research/cog/cog/COG5848/">COG5848</a></td>
<td>
D
T
</td>
<td>SigmaK-processing regulatory protein BofA (Bypass-of-forespore protein A)</td>
</tr>
<tr>
<td>118</td>
<td>118</td>
<td><a href="/research/cog/cog/COG5849/">COG5849</a></td>
<td>
D
T
</td>
<td>SigmaK checkpoint regulator BofC (Bypass-of-forespore protein C)</td>
</tr>
<tr>
<td>98</td>
<td>191</td>
<td><a href="/research/cog/cog/COG5850/">COG5850</a></td>
<td>
K
D
</td>
<td>Prespore-specific transcriptional regulator RsfA</td>
</tr>
<tr>
<td>66</td>
<td>133</td>
<td><a href="/research/cog/cog/COG5851/">COG5851</a></td>
<td>
L
D
</td>
<td>Stage 0 sporulation inhibitor Sda, checkpoint for initiation of sporulation and replication</td>
</tr>
<tr>
<td>228</td>
<td>630</td>
<td><a href="/research/cog/cog/COG5852/">COG5852</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspA/SspB/SspC/SspD (alpha/beta-type)</td>
</tr>
<tr>
<td>63</td>
<td>66</td>
<td><a href="/research/cog/cog/COG5853/">COG5853</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspE (gamma-type)</td>
</tr>
<tr>
<td>137</td>
<td>141</td>
<td><a href="/research/cog/cog/COG5854/">COG5854</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspF (alpha/beta-type)</td>
</tr>
<tr>
<td>95</td>
<td>135</td>
<td><a href="/research/cog/cog/COG5855/">COG5855</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspH/YfjU</td>
</tr>
<tr>
<td>87</td>
<td>87</td>
<td><a href="/research/cog/cog/COG5856/">COG5856</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspI</td>
</tr>
<tr>
<td>44</td>
<td>44</td>
<td><a href="/research/cog/cog/COG5857/">COG5857</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspK</td>
</tr>
<tr>
<td>31</td>
<td>31</td>
<td><a href="/research/cog/cog/COG5858/">COG5858</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspL</td>
</tr>
<tr>
<td>39</td>
<td>39</td>
<td><a href="/research/cog/cog/COG5859/">COG5859</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspN</td>
</tr>
<tr>
<td>36</td>
<td>36</td>
<td><a href="/research/cog/cog/COG5860/">COG5860</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspO/CotK</td>
</tr>
<tr>
<td>50</td>
<td>50</td>
<td><a href="/research/cog/cog/COG5861/">COG5861</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SspP/CotL</td>
</tr>
<tr>
<td>21</td>
<td>21</td>
<td><a href="/research/cog/cog/COG5862/">COG5862</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein CsgA</td>
</tr>
<tr>
<td>89</td>
<td>90</td>
<td><a href="/research/cog/cog/COG5863/">COG5863</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein Tlp (thioredoxin-like protein)</td>
</tr>
<tr>
<td>96</td>
<td>107</td>
<td><a href="/research/cog/cog/COG5864/">COG5864</a></td>
<td>
D
</td>
<td>Small acid-soluble spore protein SAS2, clostridial type</td>
</tr>
<tr>
<td>110</td>
<td>110</td>
<td><a href="/research/cog/cog/COG5865/">COG5865</a></td>
<td>
K
D
</td>
<td>Forespore-specific anti-sigma-G factor CsfB/Gin</td>
</tr>
<tr>
<td>133</td>
<td>143</td>
<td><a href="/research/cog/cog/COG5866/">COG5866</a></td>
<td>
D
O
</td>
<td>Sporulation-specific protease YabG</td>
</tr>
<tr>
<td>90</td>
<td>90</td>
<td><a href="/research/cog/cog/COG5867/">COG5867</a></td>
<td>
D
T
</td>
<td>Anti-sigma-F factor Fin</td>
</tr>
<tr>
<td>236</td>
<td>236</td>
<td><a href="/research/cog/cog/COG5868/">COG5868</a></td>
<td>
D
</td>
<td>Sporulation protein YabP</td>
</tr>
<tr>
<td>195</td>
<td>195</td>
<td><a href="/research/cog/cog/COG5869/">COG5869</a></td>
<td>
D
</td>
<td>Spore cortex formation membrane protein YabQ</td>
</tr>
<tr>
<td>40</td>
<td>40</td>
<td><a href="/research/cog/cog/COG5870/">COG5870</a></td>
<td>
K
D
</td>
<td>Uncharacterized sporulation protein YbaK, contains DUF2521 domain (not related to E. coli deacylase YbaK, COG2606)</td>
</tr>
<tr>
<td>223</td>
<td>223</td>
<td><a href="/research/cog/cog/COG5871/">COG5871</a></td>
<td>
D
</td>
<td>Spore cortex protein YqfC, YabP family</td>
</tr>
<tr>
<td>236</td>
<td>238</td>
<td><a href="/research/cog/cog/COG5872/">COG5872</a></td>
<td>
D
</td>
<td>Stage IV sporulation protein YqfD</td>
</tr>
<tr>
<td>63</td>
<td>63</td>
<td><a href="/research/cog/cog/COG5873/">COG5873</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YqzE</td>
</tr>
<tr>
<td>153</td>
<td>153</td>
<td><a href="/research/cog/cog/COG5874/">COG5874</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YtxC</td>
</tr>
<tr>
<td>194</td>
<td>201</td>
<td><a href="/research/cog/cog/COG5875/">COG5875</a></td>
<td>
D
</td>
<td>Membrane fission protein FisB/YunB</td>
</tr>
<tr>
<td>190</td>
<td>239</td>
<td><a href="/research/cog/cog/COG5878/">COG5878</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YyaC,contains DUF1256 domain</td>
</tr>
<tr>
<td>56</td>
<td>72</td>
<td><a href="/research/cog/cog/COG5879/">COG5879</a></td>
<td>
D
</td>
<td>Spore coat protein CotD</td>
</tr>
<tr>
<td>95</td>
<td>101</td>
<td><a href="/research/cog/cog/COG5880/">COG5880</a></td>
<td>
D
</td>
<td>Spore coat protein CotE</td>
</tr>
<tr>
<td>219</td>
<td>381</td>
<td><a href="/research/cog/cog/COG5881/">COG5881</a></td>
<td>
D
</td>
<td>Spore coat protein CotI/CotS, protein kinase superfamily</td>
</tr>
<tr>
<td>59</td>
<td>59</td>
<td><a href="/research/cog/cog/COG5882/">COG5882</a></td>
<td>
D
</td>
<td>Spore coat protein CotJA, required for the assembly of CotJC</td>
</tr>
<tr>
<td>172</td>
<td>185</td>
<td><a href="/research/cog/cog/COG5883/">COG5883</a></td>
<td>
D
</td>
<td>Spore coat protein CotJB</td>
</tr>
<tr>
<td>98</td>
<td>170</td>
<td><a href="/research/cog/cog/COG5884/">COG5884</a></td>
<td>
D
W
</td>
<td>Biofilm matrix protein TasA/Spore protein CotN, contains M73-like domain</td>
</tr>
<tr>
<td>37</td>
<td>39</td>
<td><a href="/research/cog/cog/COG5885/">COG5885</a></td>
<td>
D
</td>
<td>Spore coat protein CotO/YjbX</td>
</tr>
<tr>
<td>35</td>
<td>56</td>
<td><a href="/research/cog/cog/COG5886/">COG5886</a></td>
<td>
D
</td>
<td>Spore coat protein CotV/CotX (outer spore coat)</td>
</tr>
<tr>
<td>26</td>
<td>26</td>
<td><a href="/research/cog/cog/COG5887/">COG5887</a></td>
<td>
D
</td>
<td>Spore coat protein CotW (outer spore coat)</td>
</tr>
<tr>
<td>43</td>
<td>67</td>
<td><a href="/research/cog/cog/COG5888/">COG5888</a></td>
<td>
D
</td>
<td>Spore coat protein CotY/CotZ (outer spore coat)</td>
</tr>
<tr>
<td>122</td>
<td>135</td>
<td><a href="/research/cog/cog/COG5889/">COG5889</a></td>
<td>
D
</td>
<td>Spore coat protein GerQ/YwdL (inner spore coat)</td>
</tr>
<tr>
<td>201</td>
<td>241</td>
<td><a href="/research/cog/cog/COG5890/">COG5890</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation proteins YjcM and YhbB, contain C-terminal amidase domain</td>
</tr>
<tr>
<td>225</td>
<td>517</td>
<td><a href="/research/cog/cog/COG5891/">COG5891</a></td>
<td>
D
</td>
<td>Spore coat protein YheC/YheD, ATP-grasp superfamily</td>
</tr>
<tr>
<td>58</td>
<td>58</td>
<td><a href="/research/cog/cog/COG5892/">COG5892</a></td>
<td>
D
</td>
<td>Spore coat protein YlbD, FlgN family</td>
</tr>
<tr>
<td>64</td>
<td>69</td>
<td><a href="/research/cog/cog/COG5894/">COG5894</a></td>
<td>
D
</td>
<td>Spore coat protein YppG</td>
</tr>
<tr>
<td>23</td>
<td>23</td>
<td><a href="/research/cog/cog/COG5895/">COG5895</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YpzA, contains DUF2564 domain</td>
</tr>
<tr>
<td>51</td>
<td>90</td>
<td><a href="/research/cog/cog/COG5896/">COG5896</a></td>
<td>
D
</td>
<td>Spore coat protein YraE/YraG</td>
</tr>
<tr>
<td>79</td>
<td>81</td>
<td><a href="/research/cog/cog/COG5897/">COG5897</a></td>
<td>
D
</td>
<td>Spore coat protein YsxE, aminoglycoside phosphotransferase family</td>
</tr>
<tr>
<td>36</td>
<td>37</td>
<td><a href="/research/cog/cog/COG5898/">COG5898</a></td>
<td>
D
</td>
<td>Spore coat protein YuzC (inner spore coat)</td>
</tr>
<tr>
<td>25</td>
<td>48</td>
<td><a href="/research/cog/cog/COG5899/">COG5899</a></td>
<td>
D
</td>
<td>Spore coat protein YwqH</td>
</tr>
<tr>
<td>105</td>
<td>212</td>
<td><a href="/research/cog/cog/COG5900/">COG5900</a></td>
<td>
D
</td>
<td>Spore coat protein YybI (inner spore coat)</td>
</tr>
<tr>
<td>206</td>
<td>715</td>
<td><a href="/research/cog/cog/COG5901/">COG5901</a></td>
<td>
D
</td>
<td>Spore germination receptor GerABC, GerA subunit (L-alanine receptor)</td>
</tr>
<tr>
<td>203</td>
<td>811</td>
<td><a href="/research/cog/cog/COG5902/">COG5902</a></td>
<td>
D
</td>
<td>Spore germination receptor GerABC, GerB subunit (amino acid transporter)</td>
</tr>
<tr>
<td>205</td>
<td>753</td>
<td><a href="/research/cog/cog/COG5903/">COG5903</a></td>
<td>
D
</td>
<td>Spore germination receptor GerABC, GerC subunit</td>
</tr>
<tr>
<td>90</td>
<td>91</td>
<td><a href="/research/cog/cog/COG5904/">COG5904</a></td>
<td>
D
</td>
<td>Spore germination receptor GerD</td>
</tr>
<tr>
<td>966</td>
<td>2208</td>
<td><a href="/research/cog/cog/COG5905/">COG5905</a></td>
<td>
K
D
</td>
<td>Spore transcriptional regulator GerE (stand-alone HTH domain)</td>
</tr>
<tr>
<td>50</td>
<td>128</td>
<td><a href="/research/cog/cog/COG5906/">COG5906</a></td>
<td>
D
</td>
<td>Spore germination protein GerPA/GerPF (inner spore coat)</td>
</tr>
<tr>
<td>44</td>
<td>45</td>
<td><a href="/research/cog/cog/COG5907/">COG5907</a></td>
<td>
D
</td>
<td>Spore germination protein GerPB, DUF2539 family (inner spore coat)</td>
</tr>
<tr>
<td>48</td>
<td>50</td>
<td><a href="/research/cog/cog/COG5908/">COG5908</a></td>
<td>
D
</td>
<td>Spore germination protein GerPC (inner spore coat)</td>
</tr>
<tr>
<td>43</td>
<td>44</td>
<td><a href="/research/cog/cog/COG5909/">COG5909</a></td>
<td>
D
</td>
<td>Spore germination protein GerPD (inner spore coat)</td>
</tr>
<tr>
<td>43</td>
<td>43</td>
<td><a href="/research/cog/cog/COG5910/">COG5910</a></td>
<td>
D
</td>
<td>Spore germination protein GerPE (inner spore coat)</td>
</tr>
<tr>
<td>234</td>
<td>235</td>
<td><a href="/research/cog/cog/COG5911/">COG5911</a></td>
<td>
D
</td>
<td>Spore germination protease Gpr</td>
</tr>
<tr>
<td>135</td>
<td>327</td>
<td><a href="/research/cog/cog/COG5912/">COG5912</a></td>
<td>
D
</td>
<td>Spore cortex protein CoxA (YrbB), YhcN/YlaJ family</td>
</tr>
<tr>
<td>161</td>
<td>186</td>
<td><a href="/research/cog/cog/COG5914/">COG5914</a></td>
<td>
D
</td>
<td>Spore germination protein YpeB, HAD superfamily, activates cortex-lytic enzyme SleB</td>
</tr>
<tr>
<td>68</td>
<td>73</td>
<td><a href="/research/cog/cog/COG5915/">COG5915</a></td>
<td>
D
</td>
<td>Transglutaminase</td>
</tr>
<tr>
<td>53</td>
<td>53</td>
<td><a href="/research/cog/cog/COG5916/">COG5916</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YfkD</td>
</tr>
<tr>
<td>53</td>
<td>53</td>
<td><a href="/research/cog/cog/COG5917/">COG5917</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YjbA, contains UPF0736/DUF3603 domain</td>
</tr>
<tr>
<td>114</td>
<td>146</td>
<td><a href="/research/cog/cog/COG5918/">COG5918</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YmfJ, contains DUF3243 domain</td>
</tr>
<tr>
<td>56</td>
<td>67</td>
<td><a href="/research/cog/cog/COG5919/">COG5919</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YodI</td>
</tr>
<tr>
<td>53</td>
<td>53</td>
<td><a href="/research/cog/cog/COG5920/">COG5920</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YqfT, contains DUF2624 domain</td>
</tr>
<tr>
<td>134</td>
<td>149</td>
<td><a href="/research/cog/cog/COG5921/">COG5921</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YqfX, contains DUF308 domain</td>
</tr>
<tr>
<td>86</td>
<td>87</td>
<td><a href="/research/cog/cog/COG5922/">COG5922</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YqhG</td>
</tr>
<tr>
<td>178</td>
<td>185</td>
<td><a href="/research/cog/cog/COG5923/">COG5923</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation membrane protein YrzE, contains DUF3792 domain</td>
</tr>
<tr>
<td>167</td>
<td>167</td>
<td><a href="/research/cog/cog/COG5924/">COG5924</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YtfI, contains DUF2953 domain</td>
</tr>
<tr>
<td>102</td>
<td>102</td>
<td><a href="/research/cog/cog/COG5925/">COG5925</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation membrane protein YtrH/SpoVIGA</td>
</tr>
<tr>
<td>80</td>
<td>81</td>
<td><a href="/research/cog/cog/COG5926/">COG5926</a></td>
<td>
D
</td>
<td>Uncharacterized sporulation protein YtrI</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</section>
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