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<meta name="keywords" content="C5676995, cardiomyopathy, dilated, 2g, cmd2g, disease or syndrome, lmod2, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Dilated cardiomyopathy-2G (CMD2G) is characterized by early-onset severe dilated cardiomyopathy that progresses rapidly to heart failure in the neonatal period without evidence of intervening hypertrophy. Cardiac tissue exhibits markedly shortened thin filaments, disorganized myofibrils, and reduced contractile force generation, resulting in the severe ventricular dysfunction observed. There is no evidence of skeletal muscle hypertrophy (Ahrens-Nicklas et al., 2019). For a general phenotypic description and a discussion of genetic heterogeneity of dilated cardiomyopathy, see 115200." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=1801983
|
||
ConceptID=C5676995
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Cardiomyopathy, dilated, 2G<span class="h1sub">(CMD2G)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1801983</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C5676995</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>CARDIOMYOPATHY, DILATED, 2G; CMD2G</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="LMOD2 - ID: 442721 - NCBI Gene" href="/gene/442721" class="medgenPMinfo">LMOD2</a> (7q31.32)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0030887" target="_blank">MONDO:0030887</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/619897" target="_blank">619897</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Dilated cardiomyopathy-2G (CMD2G) is characterized by early-onset severe dilated cardiomyopathy that progresses rapidly to heart failure in the neonatal period without evidence of intervening hypertrophy. Cardiac tissue exhibits markedly shortened thin filaments, disorganized myofibrils, and reduced contractile force generation, resulting in the severe ventricular dysfunction observed. There is no evidence of skeletal muscle hypertrophy (Ahrens-Nicklas et al., 2019). For a general phenotypic description and a discussion of genetic heterogeneity of dilated cardiomyopathy, see 115200. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
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<div class="portlet mgSection" id="ID_102">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_8153"><div><strong>Aortic regurgitation</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>8153</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0003504</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An insufficiency of the aortic valve, leading to regurgitation (backward flow) of blood from the aorta into the left ventricle.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/8153">Feature record</a> | <a href="/medgen?term=%22Aortic%20regurgitation%22%5BClinical%20Features%5D%20OR%208153%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_2880"><div><strong>Primary dilated cardiomyopathy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2880</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0007193</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial dilated cardiomyopathy is a genetic form of heart disease. It occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of the heart, causing the open area of the chamber to become enlarged (dilated). As a result, the heart is unable to pump blood as efficiently as usual. To compensate, the heart attempts to increase the amount of blood being pumped through the heart, leading to further thinning and weakening of the cardiac muscle. Over time, this condition results in heart failure.\n\nIt usually takes many years for symptoms of familial dilated cardiomyopathy to cause health problems. They typically begin in mid-adulthood, but can occur at any time from infancy to late adulthood. Signs and symptoms of familial dilated cardiomyopathy can include an irregular heartbeat (arrhythmia), shortness of breath (dyspnea), extreme tiredness (fatigue), fainting episodes (syncope), and swelling of the legs and feet. In some cases, the first sign of the disorder is sudden cardiac death. The severity of the condition varies among affected individuals, even in members of the same family.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/2880">Feature record</a> | <a href="/medgen?term=%22Primary%20dilated%20cardiomyopathy%22%5BClinical%20Features%5D%20OR%202880%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_7670"><div><strong>Mitral regurgitation</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>7670</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0026266</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An abnormality of the mitral valve characterized by insufficiency or incompetence of the mitral valve resulting in retrograde leaking of blood through the mitral valve upon ventricular contraction.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/7670">Feature record</a> | <a href="/medgen?term=%22Mitral%20regurgitation%22%5BClinical%20Features%5D%20OR%207670%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_18315"><div><strong>Paroxysmal ventricular tachycardia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>18315</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0030591</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Episodes of ventricular tachycardia that have a sudden onset and ending.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/18315">Feature record</a> | <a href="/medgen?term=%22Paroxysmal%20ventricular%20tachycardia%22%5BClinical%20Features%5D%20OR%2018315%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_48650"><div><strong>Cardiogenic shock</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>48650</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0036980</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Pathologic Function</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Severely decreased cardiac output with evidence of inadequate end-organ perfusion (i.e., tissue hypoxia) in the presence of adequate intravascular volume.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/48650">Feature record</a> | <a href="/medgen?term=%22Cardiogenic%20shock%22%5BClinical%20Features%5D%20OR%2048650%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_21453"><div><strong>Tachycardia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>21453</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0039231</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rapid heartrate that exceeds the range of the normal resting heartrate for age.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/21453">Feature record</a> | <a href="/medgen?term=%22Tachycardia%22%5BClinical%20Features%5D%20OR%2021453%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_11911"><div><strong>Tricuspid regurgitation</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>11911</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0040961</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Failure of the tricuspid valve to close sufficiently upon contraction of the right ventricle, causing blood to regurgitate (flow backward) into the right atrium.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/11911">Feature record</a> | <a href="/medgen?term=%22Tricuspid%20regurgitation%22%5BClinical%20Features%5D%20OR%2011911%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_88445"><div><strong>Right bundle branch block</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>88445</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0085615</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A conduction block of the right branch of the bundle of His. This manifests as a prolongation of the QRS complex (greater than 0.12 s) with delayed activation of the right ventricle and terminal delay on the EKG.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/88445">Feature record</a> | <a href="/medgen?term=%22Right%20bundle%20branch%20block%22%5BClinical%20Features%5D%20OR%2088445%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_66362"><div><strong>Multifocal atrial tachycardia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>66362</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0221158</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Multifocal atrial tachycardia is a rare supraventricular arrhythmia in neonates and young infants that is characterized by multiple P waves with varying P wave morphology and is usually asymptomatic.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/66362">Feature record</a> | <a href="/medgen?term=%22Multifocal%20atrial%20tachycardia%22%5BClinical%20Features%5D%20OR%2066362%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_536845"><div><strong>Left atrial enlargement</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>536845</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0238705</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Increase in size of the left atrium.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/536845">Feature record</a> | <a href="/medgen?term=%22Left%20atrial%20enlargement%22%5BClinical%20Features%5D%20OR%20536845%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_91027"><div><strong>Monomorphic ventricular tachycardia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>91027</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0344431</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A type of ventricular tachycardia that is characterized by uniform QRS complexes within each lead (i.e., each QRS is identical or nearly so).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/91027">Feature record</a> | <a href="/medgen?term=%22Monomorphic%20ventricular%20tachycardia%22%5BClinical%20Features%5D%20OR%2091027%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_423648"><div><strong>Cerebral hemorrhage</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>423648</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2937358</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Pathologic Function</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hemorrhage into the parenchyma of the brain.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/423648">Feature record</a> | <a href="/medgen?term=%22Cerebral%20hemorrhage%22%5BClinical%20Features%5D%20OR%20423648%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_1615672"><div><strong>Myofiber disarray</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1615672</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3671015</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A nonparallel arrangement of cardiac myocytes.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1615672">Feature record</a> | <a href="/medgen?term=%22Myofiber%20disarray%22%5BClinical%20Features%5D%20OR%201615672%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_868396"><div><strong>Severely reduced left ventricular ejection fraction</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>868396</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4022790</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A large reduction in the fraction of blood pumped from the left ventricle with each cardiac cycle. The normal range in adults is at over 50 percent, and a severe reduction is defined as less than 30 percent.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/868396">Feature record</a> | <a href="/medgen?term=%22Severely%20reduced%20left%20ventricular%20ejection%20fraction%22%5BClinical%20Features%5D%20OR%20868396%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_1716989"><div><strong>Increased Z-disc width</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1716989</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5397994</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Abnormally increased width of the Z-disk of the sarcomere, resulting from splitting or opening of the Z-disc (c.f., Figure 2 of PMID:28732005).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1716989">Feature record</a> | <a href="/medgen?term=%22Increased%20Z-disc%20width%22%5BClinical%20Features%5D%20OR%201716989%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_1625775"><div><strong>Myocardial sarcomeric disarray</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1625775</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4531190</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A disruption of the structure of the sarcomeres of cardiomyocytes. The sarcomere is the repeating unit between two Z lines comprised largely of myosin and actin that mediates contractility, and normally sarcomeres are aligned with the long axis of cells, with the Z bands being in register throughout the length of the cardiac myocytes.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1625775">Feature record</a> | <a href="/medgen?term=%22Myocardial%20sarcomeric%20disarray%22%5BClinical%20Features%5D%20OR%201625775%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormal cellular phenotype</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1625775" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Myocardial sarcomeric disarray</a></span></li></ul></li><li><span class="TLline">Abnormality of the cardiovascular system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_8153" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Aortic regurgitation</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_48650" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cardiogenic shock</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_423648" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cerebral hemorrhage</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_536845" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Left atrial enlargement</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_7670" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mitral regurgitation</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_91027" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Monomorphic ventricular tachycardia</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_66362" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Multifocal atrial tachycardia</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1615672" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Myofiber disarray</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_18315" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Paroxysmal ventricular tachycardia</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_2880" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Primary dilated cardiomyopathy</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_88445" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Right bundle branch block</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_868396" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Severely reduced left ventricular ejection fraction</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_21453" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Tachycardia</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_11911" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Tricuspid regurgitation</a></span></li></ul></li><li><span class="TLline">Abnormality of the musculoskeletal system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1716989" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Increased Z-disc width</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/14559127">Treatment of acute inflammatory cardiomyopathy with intravenous immunoglobulin ameliorates left ventricular function associated with suppression of inflammatory cytokines and decreased oxidative stress.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kishimoto C,
|
||
Shioji K,
|
||
Kinoshita M,
|
||
Iwase T,
|
||
Tamaki S,
|
||
Fujii M,
|
||
Murashige A,
|
||
Maruhashi H,
|
||
Takeda S,
|
||
Nonogi H,
|
||
Hashimoto T</span><br />
|
||
<span class="medgenPMjournal">Int J Cardiol</span>
|
||
2003 Oct;91(2-3):173-8.
|
||
doi: 10.1016/s0167-5273(03)00002-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14559127" target="_blank">14559127</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7933427">Management of heart failure. II. Counseling, education, and lifestyle modifications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dracup K,
|
||
Baker DW,
|
||
Dunbar SB,
|
||
Dacey RA,
|
||
Brooks NH,
|
||
Johnson JC,
|
||
Oken C,
|
||
Massie BM</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
1994 Nov 9;272(18):1442-6.
|
||
doi: 10.1001/jama.1994.03520180066037.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7933427" target="_blank">7933427</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1943242">Predictive value of early electrophysiologic testing in determining long-term outcome with amiodarone treatment in patients with sustained ventricular tachycardia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shannon JA,
|
||
Hammill SC,
|
||
Gersh BJ</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
1991 Nov;66(11):1114-9.
|
||
doi: 10.1016/s0025-6196(12)65790-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1943242" target="_blank">1943242</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(cardiomyopathy%2C%20dilated%2C%202g)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37778991">Evaluation of Left Ventricular Mass in Different Cardiac Geometry Using Three-Dimensional Contrast-Enhanced Echocardiography.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang M,
|
||
Chen X,
|
||
Yang F,
|
||
Song Y,
|
||
Zhang D,
|
||
Chen Q,
|
||
Ma Y,
|
||
Wang S,
|
||
Ji D,
|
||
Duan Z,
|
||
Zhang L,
|
||
Wang Q</span><br />
|
||
<span class="medgenPMjournal">Int Heart J</span>
|
||
2023;64(5):885-893.
|
||
doi: 10.1536/ihj.22-663.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37778991" target="_blank">37778991</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37735995">Predictive value for mortality of left ventricular wall thickness in dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li J,
|
||
Feng YY,
|
||
Hu CA,
|
||
Zhao Y,
|
||
Hou JP,
|
||
Xu H,
|
||
Dou LN,
|
||
Lou M,
|
||
Han B</span><br />
|
||
<span class="medgenPMjournal">ESC Heart Fail</span>
|
||
2023 Dec;10(6):3538-3545.
|
||
Epub 2023 Sep 22
|
||
doi: 10.1002/ehf2.14534.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37735995" target="_blank">37735995</a><a href="/pmc/articles/PMC10682886" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33347677">Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double-blind, randomized, placebo-controlled clinical trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hazebroek MR,
|
||
Henkens MTHM,
|
||
Raafs AG,
|
||
Verdonschot JAJ,
|
||
Merken JJ,
|
||
Dennert RM,
|
||
Eurlings C,
|
||
Abdul Hamid MA,
|
||
Wolffs PFG,
|
||
Winkens B,
|
||
Brunner-La Rocca HP,
|
||
Knackstedt C,
|
||
van Paassen P,
|
||
van Empel VPM,
|
||
Heymans SRB</span><br />
|
||
<span class="medgenPMjournal">Eur J Heart Fail</span>
|
||
2021 Feb;23(2):302-309.
|
||
Epub 2021 Jan 7
|
||
doi: 10.1002/ejhf.2082.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33347677" target="_blank">33347677</a><a href="/pmc/articles/PMC8048650" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32835416">Intravenous immunoglobulin for presumed viral myocarditis in children and adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Robinson J,
|
||
Hartling L,
|
||
Vandermeer B,
|
||
Sebastianski M,
|
||
Klassen TP</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2020 Aug 19;8(8):CD004370.
|
||
doi: 10.1002/14651858.CD004370.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32835416" target="_blank">32835416</a><a href="/pmc/articles/PMC8210245" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2463576">Efficacy and safety of low doses of beta-blocker agents combined with amiodarone in refractory ventricular tachycardia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tonet J,
|
||
Frank R,
|
||
Fontaine G,
|
||
Grosgogeat Y</span><br />
|
||
<span class="medgenPMjournal">Pacing Clin Electrophysiol</span>
|
||
1988 Nov;11(11 Pt 2):1984-9.
|
||
doi: 10.1111/j.1540-8159.1988.tb06338.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2463576" target="_blank">2463576</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Cardiomyopathy%2C%20dilated%2C%202G%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (26)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37752589">TCAP gene is not a common cause of cardiomyopathy in Iranian patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alaei Z,
|
||
Zamani N,
|
||
Rabbani B,
|
||
Mahdieh N</span><br />
|
||
<span class="medgenPMjournal">Eur J Med Res</span>
|
||
2023 Sep 26;28(1):376.
|
||
doi: 10.1186/s40001-023-01019-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37752589" target="_blank">37752589</a><a href="/pmc/articles/PMC10523715" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32835416">Intravenous immunoglobulin for presumed viral myocarditis in children and adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Robinson J,
|
||
Hartling L,
|
||
Vandermeer B,
|
||
Sebastianski M,
|
||
Klassen TP</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2020 Aug 19;8(8):CD004370.
|
||
doi: 10.1002/14651858.CD004370.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32835416" target="_blank">32835416</a><a href="/pmc/articles/PMC8210245" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28541593">Clinical and prognostic relevancy of left ventricular trabeculation assessed by cardiac magnetic resonance in patients with dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mazurkiewicz Ł,
|
||
Petryka J,
|
||
Śpiewak M,
|
||
Miłosz-Wieczorek B,
|
||
Małek ŁA,
|
||
Jasińska A,
|
||
Jarmus E,
|
||
Marczak M,
|
||
Misko J,
|
||
Grzybowski J</span><br />
|
||
<span class="medgenPMjournal">Kardiol Pol</span>
|
||
2017;75(8):794-803.
|
||
Epub 2017 May 25
|
||
doi: 10.5603/KP.a2017.0097.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28541593" target="_blank">28541593</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26004942">Myocardial scar predicts monomorphic ventricular tachycardia but not polymorphic ventricular tachycardia or ventricular fibrillation in nonischemic dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Piers SR,
|
||
Everaerts K,
|
||
van der Geest RJ,
|
||
Hazebroek MR,
|
||
Siebelink HM,
|
||
Pison LA,
|
||
Schalij MJ,
|
||
Bekkers SC,
|
||
Heymans S,
|
||
Zeppenfeld K</span><br />
|
||
<span class="medgenPMjournal">Heart Rhythm</span>
|
||
2015 Oct;12(10):2106-14.
|
||
Epub 2015 May 22
|
||
doi: 10.1016/j.hrthm.2015.05.026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26004942" target="_blank">26004942</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2463576">Efficacy and safety of low doses of beta-blocker agents combined with amiodarone in refractory ventricular tachycardia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tonet J,
|
||
Frank R,
|
||
Fontaine G,
|
||
Grosgogeat Y</span><br />
|
||
<span class="medgenPMjournal">Pacing Clin Electrophysiol</span>
|
||
1988 Nov;11(11 Pt 2):1984-9.
|
||
doi: 10.1111/j.1540-8159.1988.tb06338.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2463576" target="_blank">2463576</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Cardiomyopathy%2C%20dilated%2C%202G%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (16)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33347677">Intravenous immunoglobulin therapy in adult patients with idiopathic chronic cardiomyopathy and cardiac parvovirus B19 persistence: a prospective, double-blind, randomized, placebo-controlled clinical trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hazebroek MR,
|
||
Henkens MTHM,
|
||
Raafs AG,
|
||
Verdonschot JAJ,
|
||
Merken JJ,
|
||
Dennert RM,
|
||
Eurlings C,
|
||
Abdul Hamid MA,
|
||
Wolffs PFG,
|
||
Winkens B,
|
||
Brunner-La Rocca HP,
|
||
Knackstedt C,
|
||
van Paassen P,
|
||
van Empel VPM,
|
||
Heymans SRB</span><br />
|
||
<span class="medgenPMjournal">Eur J Heart Fail</span>
|
||
2021 Feb;23(2):302-309.
|
||
Epub 2021 Jan 7
|
||
doi: 10.1002/ejhf.2082.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33347677" target="_blank">33347677</a><a href="/pmc/articles/PMC8048650" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33225554">Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy: insights from TRED-HF.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Halliday BP,
|
||
Owen R,
|
||
Gregson J,
|
||
S Vassiliou V,
|
||
Chen X,
|
||
Wage R,
|
||
Lota AS,
|
||
Khalique Z,
|
||
Tayal U,
|
||
Hammersley DJ,
|
||
Jones RE,
|
||
Baksi AJ,
|
||
Cowie MR,
|
||
Cleland JGF,
|
||
Pennell DJ,
|
||
Prasad SK</span><br />
|
||
<span class="medgenPMjournal">Eur J Heart Fail</span>
|
||
2021 Feb;23(2):293-301.
|
||
Epub 2020 Dec 14
|
||
doi: 10.1002/ejhf.2063.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33225554" target="_blank">33225554</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32835416">Intravenous immunoglobulin for presumed viral myocarditis in children and adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Robinson J,
|
||
Hartling L,
|
||
Vandermeer B,
|
||
Sebastianski M,
|
||
Klassen TP</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2020 Aug 19;8(8):CD004370.
|
||
doi: 10.1002/14651858.CD004370.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32835416" target="_blank">32835416</a><a href="/pmc/articles/PMC8210245" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20386074">Intravenous immunoglobulin therapy for patients with idiopathic cardiomyopathy and endomyocardial biopsy-proven high PVB19 viral load.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dennert R,
|
||
Velthuis S,
|
||
Schalla S,
|
||
Eurlings L,
|
||
van Suylen RJ,
|
||
van Paassen P,
|
||
Tervaert JW,
|
||
Wolffs P,
|
||
Goossens VJ,
|
||
Bruggeman C,
|
||
Waltenberger J,
|
||
Crijns HJ,
|
||
Heymans S</span><br />
|
||
<span class="medgenPMjournal">Antivir Ther</span>
|
||
2010;15(2):193-201.
|
||
doi: 10.3851/IMP1516.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20386074" target="_blank">20386074</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2463576">Efficacy and safety of low doses of beta-blocker agents combined with amiodarone in refractory ventricular tachycardia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tonet J,
|
||
Frank R,
|
||
Fontaine G,
|
||
Grosgogeat Y</span><br />
|
||
<span class="medgenPMjournal">Pacing Clin Electrophysiol</span>
|
||
1988 Nov;11(11 Pt 2):1984-9.
|
||
doi: 10.1111/j.1540-8159.1988.tb06338.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2463576" target="_blank">2463576</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Cardiomyopathy%2C%20dilated%2C%202G%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37752589">TCAP gene is not a common cause of cardiomyopathy in Iranian patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alaei Z,
|
||
Zamani N,
|
||
Rabbani B,
|
||
Mahdieh N</span><br />
|
||
<span class="medgenPMjournal">Eur J Med Res</span>
|
||
2023 Sep 26;28(1):376.
|
||
doi: 10.1186/s40001-023-01019-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37752589" target="_blank">37752589</a><a href="/pmc/articles/PMC10523715" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37735995">Predictive value for mortality of left ventricular wall thickness in dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li J,
|
||
Feng YY,
|
||
Hu CA,
|
||
Zhao Y,
|
||
Hou JP,
|
||
Xu H,
|
||
Dou LN,
|
||
Lou M,
|
||
Han B</span><br />
|
||
<span class="medgenPMjournal">ESC Heart Fail</span>
|
||
2023 Dec;10(6):3538-3545.
|
||
Epub 2023 Sep 22
|
||
doi: 10.1002/ehf2.14534.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37735995" target="_blank">37735995</a><a href="/pmc/articles/PMC10682886" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28541593">Clinical and prognostic relevancy of left ventricular trabeculation assessed by cardiac magnetic resonance in patients with dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mazurkiewicz Ł,
|
||
Petryka J,
|
||
Śpiewak M,
|
||
Miłosz-Wieczorek B,
|
||
Małek ŁA,
|
||
Jasińska A,
|
||
Jarmus E,
|
||
Marczak M,
|
||
Misko J,
|
||
Grzybowski J</span><br />
|
||
<span class="medgenPMjournal">Kardiol Pol</span>
|
||
2017;75(8):794-803.
|
||
Epub 2017 May 25
|
||
doi: 10.5603/KP.a2017.0097.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28541593" target="_blank">28541593</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26004942">Myocardial scar predicts monomorphic ventricular tachycardia but not polymorphic ventricular tachycardia or ventricular fibrillation in nonischemic dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Piers SR,
|
||
Everaerts K,
|
||
van der Geest RJ,
|
||
Hazebroek MR,
|
||
Siebelink HM,
|
||
Pison LA,
|
||
Schalij MJ,
|
||
Bekkers SC,
|
||
Heymans S,
|
||
Zeppenfeld K</span><br />
|
||
<span class="medgenPMjournal">Heart Rhythm</span>
|
||
2015 Oct;12(10):2106-14.
|
||
Epub 2015 May 22
|
||
doi: 10.1016/j.hrthm.2015.05.026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26004942" target="_blank">26004942</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2463576">Efficacy and safety of low doses of beta-blocker agents combined with amiodarone in refractory ventricular tachycardia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tonet J,
|
||
Frank R,
|
||
Fontaine G,
|
||
Grosgogeat Y</span><br />
|
||
<span class="medgenPMjournal">Pacing Clin Electrophysiol</span>
|
||
1988 Nov;11(11 Pt 2):1984-9.
|
||
doi: 10.1111/j.1540-8159.1988.tb06338.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2463576" target="_blank">2463576</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Cardiomyopathy%2C%20dilated%2C%202G%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (19)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37752589">TCAP gene is not a common cause of cardiomyopathy in Iranian patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alaei Z,
|
||
Zamani N,
|
||
Rabbani B,
|
||
Mahdieh N</span><br />
|
||
<span class="medgenPMjournal">Eur J Med Res</span>
|
||
2023 Sep 26;28(1):376.
|
||
doi: 10.1186/s40001-023-01019-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37752589" target="_blank">37752589</a><a href="/pmc/articles/PMC10523715" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37735995">Predictive value for mortality of left ventricular wall thickness in dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li J,
|
||
Feng YY,
|
||
Hu CA,
|
||
Zhao Y,
|
||
Hou JP,
|
||
Xu H,
|
||
Dou LN,
|
||
Lou M,
|
||
Han B</span><br />
|
||
<span class="medgenPMjournal">ESC Heart Fail</span>
|
||
2023 Dec;10(6):3538-3545.
|
||
Epub 2023 Sep 22
|
||
doi: 10.1002/ehf2.14534.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37735995" target="_blank">37735995</a><a href="/pmc/articles/PMC10682886" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33225554">Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy: insights from TRED-HF.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Halliday BP,
|
||
Owen R,
|
||
Gregson J,
|
||
S Vassiliou V,
|
||
Chen X,
|
||
Wage R,
|
||
Lota AS,
|
||
Khalique Z,
|
||
Tayal U,
|
||
Hammersley DJ,
|
||
Jones RE,
|
||
Baksi AJ,
|
||
Cowie MR,
|
||
Cleland JGF,
|
||
Pennell DJ,
|
||
Prasad SK</span><br />
|
||
<span class="medgenPMjournal">Eur J Heart Fail</span>
|
||
2021 Feb;23(2):293-301.
|
||
Epub 2020 Dec 14
|
||
doi: 10.1002/ejhf.2063.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33225554" target="_blank">33225554</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28541593">Clinical and prognostic relevancy of left ventricular trabeculation assessed by cardiac magnetic resonance in patients with dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mazurkiewicz Ł,
|
||
Petryka J,
|
||
Śpiewak M,
|
||
Miłosz-Wieczorek B,
|
||
Małek ŁA,
|
||
Jasińska A,
|
||
Jarmus E,
|
||
Marczak M,
|
||
Misko J,
|
||
Grzybowski J</span><br />
|
||
<span class="medgenPMjournal">Kardiol Pol</span>
|
||
2017;75(8):794-803.
|
||
Epub 2017 May 25
|
||
doi: 10.5603/KP.a2017.0097.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28541593" target="_blank">28541593</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26004942">Myocardial scar predicts monomorphic ventricular tachycardia but not polymorphic ventricular tachycardia or ventricular fibrillation in nonischemic dilated cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Piers SR,
|
||
Everaerts K,
|
||
van der Geest RJ,
|
||
Hazebroek MR,
|
||
Siebelink HM,
|
||
Pison LA,
|
||
Schalij MJ,
|
||
Bekkers SC,
|
||
Heymans S,
|
||
Zeppenfeld K</span><br />
|
||
<span class="medgenPMjournal">Heart Rhythm</span>
|
||
2015 Oct;12(10):2106-14.
|
||
Epub 2015 May 22
|
||
doi: 10.1016/j.hrthm.2015.05.026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26004942" target="_blank">26004942</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Cardiomyopathy%2C%20dilated%2C%202G%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (9)</a></div></div>
|
||
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
|
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<div class="nl"><a target="_blank" href="/pubmed/32835416">Intravenous immunoglobulin for presumed viral myocarditis in children and adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Robinson J,
|
||
Hartling L,
|
||
Vandermeer B,
|
||
Sebastianski M,
|
||
Klassen TP</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2020 Aug 19;8(8):CD004370.
|
||
doi: 10.1002/14651858.CD004370.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32835416" target="_blank">32835416</a><a href="/pmc/articles/PMC8210245" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Cardiomyopathy%2C%20dilated%2C%202G%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C5676995%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (3)</a></li>
|
||
<li><a href="/gtr/tests?term=C5676995%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (3)</a></li>
|
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<li><a href="/gtr/tests?term=C5676995%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (3)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C5676995%5bDISCUI%5d" target="_blank">See all (3)</a></total></li>
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