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<meta name="keywords" content="C4748876, cib1, epidermodysplasia verruciformis 3, epidermodysplasia verruciformis, susceptibility to, 3, ev3, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Epidermodysplasia verruciformis-3 (EV3) is characterized by onset in childhood or early adulthood of persistent disseminated flat warts and pityriasis versicolor-like lesions of the skin that are induced by cutaneous human papillomaviruses (HPVs) of the beta genus. Some patients develop nonmelanoma skin cancer, particularly on areas of the body exposed to the sun. Patients are otherwise healthy and normally resistant to other microorganisms, including other viruses and skintropic pathogens, and even all other cutaneous and mucosal HPVs (de Jong et al., 2018). For a discussion of genetic heterogeneity of susceptibility to epidermodysplasia verruciformis, see EV1 (226400)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=1648390
|
||
ConceptID=C4748876
|
||
-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Epidermodysplasia verruciformis, susceptibility to, 3<span class="h1sub">(EV3)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648390</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4748876</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Epidermodysplasia verruciformis 3</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="CIB1 - ID: 10519 - NCBI Gene" href="/gene/10519" class="medgenPMinfo">CIB1</a> (15q26.1)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0032644" target="_blank">MONDO:0032644</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/618267" target="_blank">618267</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Epidermodysplasia verruciformis-3 (EV3) is characterized by onset in childhood or early adulthood of persistent disseminated flat warts and pityriasis versicolor-like lesions of the skin that are induced by cutaneous human papillomaviruses (HPVs) of the beta genus. Some patients develop nonmelanoma skin cancer, particularly on areas of the body exposed to the sun. Patients are otherwise healthy and normally resistant to other microorganisms, including other viruses and skintropic pathogens, and even all other cutaneous and mucosal HPVs (de Jong et al., 2018). For a discussion of genetic heterogeneity of susceptibility to epidermodysplasia verruciformis, see EV1 (226400). [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_2874"><div><strong>Squamous cell carcinoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2874</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0007137</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of squamous cell carcinoma of the skin.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/2874">Feature record</a> | <a href="/medgen?term=%22Squamous%20cell%20carcinoma%22%5BClinical%20Features%5D%20OR%202874%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_777120"><div><strong>Verrucae</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>777120</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3665596</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Warts, benign growths on the skin or mucous membranes that cause cosmetic problems as well as pain and discomfort. Warts most often occur on the hands, feet, and genital areas.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/777120">Feature record</a> | <a href="/medgen?term=%22Verrucae%22%5BClinical%20Features%5D%20OR%20777120%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_1648304"><div><strong>Skin basal cell carcinoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648304</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4721806</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of a basal cell carcinoma of the skin.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648304">Feature record</a> | <a href="/medgen?term=%22Skin%20basal%20cell%20carcinoma%22%5BClinical%20Features%5D%20OR%201648304%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_65136"><div><strong>Epidermal acanthosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>65136</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0221270</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Diffuse hypertrophy or thickening of the stratum spinosum of the epidermis (prickle cell layer of the skin).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/65136">Feature record</a> | <a href="/medgen?term=%22Epidermal%20acanthosis%22%5BClinical%20Features%5D%20OR%2065136%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_96101"><div><strong>Palmar pits</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>96101</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0423776</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/96101">Feature record</a> | <a href="/medgen?term=%22Palmar%20pits%22%5BClinical%20Features%5D%20OR%2096101%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of the integument</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_65136" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Epidermal acanthosis</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_96101" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Palmar pits</a></span></li></ul></li><li><span class="TLline">Neoplasm</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1648304" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Skin basal cell carcinoma</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_2874" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Squamous cell carcinoma</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_777120" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Verrucae</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28941263">Epidermodysplasia verruciformis: three case reports and a brief review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shruti S,
|
||
Siraj F,
|
||
Singh A,
|
||
Ramesh V</span><br />
|
||
<span class="medgenPMjournal">Acta Dermatovenerol Alp Pannonica Adriat</span>
|
||
2017 Sep;26(3):59-61.
|
||
doi: 10.15570/actaapa.2017.19.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28941263" target="_blank">28941263</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21387292">Contribution of TMC6 and TMC8 (EVER1 and EVER2) variants to cervical cancer susceptibility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Castro FA,
|
||
Ivansson EL,
|
||
Schmitt M,
|
||
Juko-Pecirep I,
|
||
Kjellberg L,
|
||
Hildesheim A,
|
||
Gyllensten UB,
|
||
Pawlita M</span><br />
|
||
<span class="medgenPMjournal">Int J Cancer</span>
|
||
2012 Jan 15;130(2):349-55.
|
||
Epub 2011 May 5
|
||
doi: 10.1002/ijc.26016.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21387292" target="_blank">21387292</a><a href="/pmc/articles/PMC3530613" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22131115">Cutaneous manifestations of human papillomaviruses: a review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cardoso JC,
|
||
Calonje E</span><br />
|
||
<span class="medgenPMjournal">Acta Dermatovenerol Alp Pannonica Adriat</span>
|
||
2011 Sep;20(3):145-54.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22131115" target="_blank">22131115</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10844558">Evidence for a nonallelic heterogeneity of epidermodysplasia verruciformis with two susceptibility loci mapped to chromosome regions 2p21-p24 and 17q25.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ramoz N,
|
||
Taïeb A,
|
||
Rueda LA,
|
||
Montoya LS,
|
||
Bouadjar B,
|
||
Favre M,
|
||
Orth G</span><br />
|
||
<span class="medgenPMjournal">J Invest Dermatol</span>
|
||
2000 Jun;114(6):1148-53.
|
||
doi: 10.1046/j.1523-1747.2000.00996.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10844558" target="_blank">10844558</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10084299">A susceptibility locus for epidermodysplasia verruciformis, an abnormal predisposition to infection with the oncogenic human papillomavirus type 5, maps to chromosome 17qter in a region containing a psoriasis locus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ramoz N,
|
||
Rueda LA,
|
||
Bouadjar B,
|
||
Favre M,
|
||
Orth G</span><br />
|
||
<span class="medgenPMjournal">J Invest Dermatol</span>
|
||
1999 Mar;112(3):259-63.
|
||
doi: 10.1046/j.1523-1747.1999.00536.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10084299" target="_blank">10084299</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Epidermodysplasia%20verruciformis%2C%20susceptibility%20to%2C%203%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (9)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30982308">Multiple flat-topped scaly violaceous papules.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Girijala RL,
|
||
Nyinawinyange D,
|
||
Parekh PK,
|
||
Grimwood RE</span><br />
|
||
<span class="medgenPMjournal">Dermatol Online J</span>
|
||
2019 Mar 15;25(3)
|
||
<span class="bold">PMID: </span><a href="/pubmed/30982308" target="_blank">30982308</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25073507">Compound heterozygous CORO1A mutations in siblings with a mucocutaneous-immunodeficiency syndrome of epidermodysplasia verruciformis-HPV, molluscum contagiosum and granulomatous tuberculoid leprosy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stray-Pedersen A,
|
||
Jouanguy E,
|
||
Crequer A,
|
||
Bertuch AA,
|
||
Brown BS,
|
||
Jhangiani SN,
|
||
Muzny DM,
|
||
Gambin T,
|
||
Sorte H,
|
||
Sasa G,
|
||
Metry D,
|
||
Campbell J,
|
||
Sockrider MM,
|
||
Dishop MK,
|
||
Scollard DM,
|
||
Gibbs RA,
|
||
Mace EM,
|
||
Orange JS,
|
||
Lupski JR,
|
||
Casanova JL,
|
||
Noroski LM</span><br />
|
||
<span class="medgenPMjournal">J Clin Immunol</span>
|
||
2014 Oct;34(7):871-90.
|
||
Epub 2014 Jul 30
|
||
doi: 10.1007/s10875-014-0074-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25073507" target="_blank">25073507</a><a href="/pmc/articles/PMC4386834" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22131115">Cutaneous manifestations of human papillomaviruses: a review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cardoso JC,
|
||
Calonje E</span><br />
|
||
<span class="medgenPMjournal">Acta Dermatovenerol Alp Pannonica Adriat</span>
|
||
2011 Sep;20(3):145-54.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22131115" target="_blank">22131115</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16854762">A case of epidermodysplasia verruciformis associated with squamous cell carcinoma and Bowen's disease: a therapeutic challenge.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baskan EB,
|
||
Tunali S,
|
||
Adim SB,
|
||
Turan A,
|
||
Toker S</span><br />
|
||
<span class="medgenPMjournal">J Dermatolog Treat</span>
|
||
2006;17(3):179-83.
|
||
doi: 10.1080/09546630600788844.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16854762" target="_blank">16854762</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Epidermodysplasia%20verruciformis%2C%20susceptibility%20to%2C%203%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30156265">A novel approach to the classification of epidermodysplasia verruciformis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang S,
|
||
Wu JH,
|
||
Lewis DJ,
|
||
Rady PL,
|
||
Tyring SK</span><br />
|
||
<span class="medgenPMjournal">Int J Dermatol</span>
|
||
2018 Nov;57(11):1344-1350.
|
||
Epub 2018 Aug 29
|
||
doi: 10.1111/ijd.14196.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30156265" target="_blank">30156265</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26954321">Treatment of Imiquimod Resistant Epidermodysplasia Verruciformis With Ingenol Mebutate.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kim C,
|
||
Hashemi P,
|
||
Caglia M,
|
||
Shulman K</span><br />
|
||
<span class="medgenPMjournal">J Drugs Dermatol</span>
|
||
2016 Mar;15(3):350-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26954321" target="_blank">26954321</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16681585">Epidermodysplasia verruciformis and generalized verrucosis: the same disease?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yanagi T,
|
||
Shibaki A,
|
||
Tsuji-Abe Y,
|
||
Yokota K,
|
||
Shimizu H</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Dermatol</span>
|
||
2006 May;31(3):390-3.
|
||
doi: 10.1111/j.1365-2230.2006.02100.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16681585" target="_blank">16681585</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/14522631">Epidermodysplasia verruciformis with multiple mucosal carcinomas treated with pegylated interferon alfa and acitretin.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gubinelli E,
|
||
Posteraro P,
|
||
Cocuroccia B,
|
||
Girolomoni G</span><br />
|
||
<span class="medgenPMjournal">J Dermatolog Treat</span>
|
||
2003 Sep;14(3):184-8.
|
||
doi: 10.1080/09546630310009699.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14522631" target="_blank">14522631</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6086930">Epidermodysplasia verruciformis: response to therapy with dialyzable leukocyte extract (transfer factor) derived from household contacts.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vasily DB,
|
||
Miller OF,
|
||
Fudenberg HH,
|
||
Goust JM,
|
||
Wilson GB</span><br />
|
||
<span class="medgenPMjournal">J Clin Lab Immunol</span>
|
||
1984 May;14(1):49-57.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6086930" target="_blank">6086930</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Epidermodysplasia%20verruciformis%2C%20susceptibility%20to%2C%203%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (7)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/26954321">Treatment of Imiquimod Resistant Epidermodysplasia Verruciformis With Ingenol Mebutate.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kim C,
|
||
Hashemi P,
|
||
Caglia M,
|
||
Shulman K</span><br />
|
||
<span class="medgenPMjournal">J Drugs Dermatol</span>
|
||
2016 Mar;15(3):350-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26954321" target="_blank">26954321</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12906855">Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kurima K,
|
||
Yang Y,
|
||
Sorber K,
|
||
Griffith AJ</span><br />
|
||
<span class="medgenPMjournal">Genomics</span>
|
||
2003 Sep;82(3):300-8.
|
||
doi: 10.1016/s0888-7543(03)00154-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12906855" target="_blank">12906855</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Epidermodysplasia%20verruciformis%2C%20susceptibility%20to%2C%203%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30541782">Metagenomic Discovery of 83 New Human Papillomavirus Types in Patients with Immunodeficiency.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pastrana DV,
|
||
Peretti A,
|
||
Welch NL,
|
||
Borgogna C,
|
||
Olivero C,
|
||
Badolato R,
|
||
Notarangelo LD,
|
||
Gariglio M,
|
||
FitzGerald PC,
|
||
McIntosh CE,
|
||
Reeves J,
|
||
Starrett GJ,
|
||
Bliskovsky V,
|
||
Velez D,
|
||
Brownell I,
|
||
Yarchoan R,
|
||
Wyvill KM,
|
||
Uldrick TS,
|
||
Maldarelli F,
|
||
Lisco A,
|
||
Sereti I,
|
||
Gonzalez CM,
|
||
Androphy EJ,
|
||
McBride AA,
|
||
Van Doorslaer K,
|
||
Garcia F,
|
||
Dvoretzky I,
|
||
Liu JS,
|
||
Han J,
|
||
Murphy PM,
|
||
McDermott DH,
|
||
Buck CB</span><br />
|
||
<span class="medgenPMjournal">mSphere</span>
|
||
2018 Dec 12;3(6)
|
||
doi: 10.1128/mSphereDirect.00645-18.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30541782" target="_blank">30541782</a><a href="/pmc/articles/PMC6291628" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19924140">Seroreactivity of 38 human papillomavirus types in epidermodysplasia verruciformis patients, relatives, and controls.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Michael KM,
|
||
Waterboer T,
|
||
Pfister H,
|
||
Gariglio M,
|
||
Majewski S,
|
||
Favre M,
|
||
Pawlita M</span><br />
|
||
<span class="medgenPMjournal">J Invest Dermatol</span>
|
||
2010 Mar;130(3):841-8.
|
||
Epub 2009 Nov 19
|
||
doi: 10.1038/jid.2009.356.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19924140" target="_blank">19924140</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12906855">Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kurima K,
|
||
Yang Y,
|
||
Sorber K,
|
||
Griffith AJ</span><br />
|
||
<span class="medgenPMjournal">Genomics</span>
|
||
2003 Sep;82(3):300-8.
|
||
doi: 10.1016/s0888-7543(03)00154-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12906855" target="_blank">12906855</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10844558">Evidence for a nonallelic heterogeneity of epidermodysplasia verruciformis with two susceptibility loci mapped to chromosome regions 2p21-p24 and 17q25.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ramoz N,
|
||
Taïeb A,
|
||
Rueda LA,
|
||
Montoya LS,
|
||
Bouadjar B,
|
||
Favre M,
|
||
Orth G</span><br />
|
||
<span class="medgenPMjournal">J Invest Dermatol</span>
|
||
2000 Jun;114(6):1148-53.
|
||
doi: 10.1046/j.1523-1747.2000.00996.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10844558" target="_blank">10844558</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10084299">A susceptibility locus for epidermodysplasia verruciformis, an abnormal predisposition to infection with the oncogenic human papillomavirus type 5, maps to chromosome 17qter in a region containing a psoriasis locus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ramoz N,
|
||
Rueda LA,
|
||
Bouadjar B,
|
||
Favre M,
|
||
Orth G</span><br />
|
||
<span class="medgenPMjournal">J Invest Dermatol</span>
|
||
1999 Mar;112(3):259-63.
|
||
doi: 10.1046/j.1523-1747.1999.00536.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10084299" target="_blank">10084299</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Epidermodysplasia%20verruciformis%2C%20susceptibility%20to%2C%203%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
||
<div class="portlet mgSection" id="ID_113">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_106">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C4748876%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (3)</a></li>
|
||
<li><a href="/gtr/tests?term=C4748876%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (2)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C4748876%5bDISCUI%5d" target="_blank">See all (4)</a></total></li>
|
||
</ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_119">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=618267" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Epidermodysplasia%20verruciformis,%20susceptibility%20to,%203" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_115">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=602293" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=10519[geneid]" target="_blank">View CIB1 variations in ClinVar</a></li><li><a href="https://catalog.coriell.org/Search?q=618267" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
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