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<meta name="keywords" content="C4551527, actn4, actn4 focal segmental glomerulosclerosis, disease or syndrome, familial idiopathic steroid-resistant nephrotic syndrome with focal segmental glomerulosclerosis, familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis, focal segmental glomerulosclerosis 1, focal segmental glomerulosclerosis caused by mutation in actn4, focal segmental glomerulosclerosis type 1, fsgs1, glomerulosclerosis, focal segmental, 1, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Focal segmental glomerulosclerosis (FSGS) is a pathologic finding in several renal disorders that manifest clinically as proteinuria and progressive decline in renal function. Some patients with FSGS develop the clinical entity called 'nephrotic syndrome' (see NPHS1; 256300), which includes massive proteinuria, hypoalbuminemia, hyperlipidemia, and edema. However, patients with FSGS may have proteinuria in the nephrotic range without other features of the nephrotic syndrome (summary by D'Agati et al., 2004; Mathis et al., 1998). D'Agati et al. (2011) provided a detailed review of FSGS, emphasizing that the disorder results from defects of the podocyte. Because of confusion in the literature regarding use of the terms 'nephrotic syndrome' and 'focal segmental glomerulosclerosis' (see NOMENCLATURE section), these disorders in OMIM are classified as NPHS or FSGS according to how they were first designated in the literature. Genetic Heterogeneity of Focal Segmental Glomerulosclerosis and Nephrotic Syndrome Focal segmental glomerulosclerosis and nephrotic syndrome are genetically heterogeneous disorders representing a spectrum of hereditary renal diseases. See also FSGS2 (603965), caused by mutation in the TRPC6 gene (603652); FSGS3 (607832), associated with variation in the CD2AP gene (604241); FSGS4 (612551), mapped to chromosome 22q12; FSGS5 (613237), caused by mutation in the INF2 gene (610982); FSGS6 (614131), caused by mutation in the MYO1E gene (601479); FSGS7 (616002), caused by mutation in the PAX2 gene (167409); FSGS8 (616032), caused by mutation in the ANLN gene (616027); FSGS9 (616220), caused by mutation in the CRB2 gene (609720); and FSGS10 (256020), caused by mutation in the LMX1B gene (602575). See also NPHS1 (256300), caused by mutation in the NPHS1 gene (602716); NPHS2 (600995), caused by mutation in the podocin gene (604766); NPHS3 (610725), caused by mutation in the PLCE1 gene (608414); NPHS4 (256370), caused by mutation in the WT1 gene (607102); NPHS5 (614199), caused by mutation in the LAMB2 gene (150325); NPHS6 (614196), caused by mutation in the PTPRO gene (600579); NPHS7 (615008), caused by mutation in the DGKE gene (601440); NPHS8 (615244), caused by mutation in the ARHGDIA gene (601925); NPHS9 (615573), caused by mutation in the COQ8B gene (615567); NPHS10 (615861), caused by mutation in the EMP2 gene (602334); NPHS11 (616730), caused by mutation in the NUP107 gene (607617); NPHS12 (616892), caused by mutation in the NUP93 gene (614351); NPHS13 (616893), caused by mutation in the NUP205 gene (614352); NPHS14 (617575), caused by mutation in the SGPL1 gene (603729); NPHS15 (617609), caused by mutation in the MAGI2 gene (606382); NPHS16 (617783), caused by mutation in the KANK2 gene (614610), NPHS17 (618176), caused by mutation in the NUP85 gene (170285); NPHS18 (618177), caused by mutation in the NUP133 gene (607613); NPHS19 (618178), caused by mutation in the NUP160 gene (607614); NPHS20 (301028), caused by mutation in the TBC1D8B gene (301027); and NPHS21 (618594) caused by mutation in the AVIL gene (613397)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=1636833
|
||
ConceptID=C4551527
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Focal segmental glomerulosclerosis 1<span class="h1sub">(FSGS1)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1636833</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4551527</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>FSGS1</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="ACTN4 - ID: 81 - NCBI Gene" href="/gene/81" class="medgenPMinfo">ACTN4</a> (19q13.2)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0011303" target="_blank">MONDO:0011303</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/603278" target="_blank">603278</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Focal segmental glomerulosclerosis (FSGS) is a pathologic finding in several renal disorders that manifest clinically as proteinuria and progressive decline in renal function. Some patients with FSGS develop the clinical entity called 'nephrotic syndrome' (see NPHS1; 256300), which includes massive proteinuria, hypoalbuminemia, hyperlipidemia, and edema. However, patients with FSGS may have proteinuria in the nephrotic range without other features of the nephrotic syndrome (summary by D'Agati et al., 2004; Mathis et al., 1998). D'Agati et al. (2011) provided a detailed review of FSGS, emphasizing that the disorder results from defects of the podocyte. Because of confusion in the literature regarding use of the terms 'nephrotic syndrome' and 'focal segmental glomerulosclerosis' (see NOMENCLATURE section), these disorders in OMIM are classified as NPHS or FSGS according to how they were first designated in the literature. Genetic Heterogeneity of Focal Segmental Glomerulosclerosis and Nephrotic Syndrome Focal segmental glomerulosclerosis and nephrotic syndrome are genetically heterogeneous disorders representing a spectrum of hereditary renal diseases. See also FSGS2 (603965), caused by mutation in the TRPC6 gene (603652); FSGS3 (607832), associated with variation in the CD2AP gene (604241); FSGS4 (612551), mapped to chromosome 22q12; FSGS5 (613237), caused by mutation in the INF2 gene (610982); FSGS6 (614131), caused by mutation in the MYO1E gene (601479); FSGS7 (616002), caused by mutation in the PAX2 gene (167409); FSGS8 (616032), caused by mutation in the ANLN gene (616027); FSGS9 (616220), caused by mutation in the CRB2 gene (609720); and FSGS10 (256020), caused by mutation in the LMX1B gene (602575). See also NPHS1 (256300), caused by mutation in the NPHS1 gene (602716); NPHS2 (600995), caused by mutation in the podocin gene (604766); NPHS3 (610725), caused by mutation in the PLCE1 gene (608414); NPHS4 (256370), caused by mutation in the WT1 gene (607102); NPHS5 (614199), caused by mutation in the LAMB2 gene (150325); NPHS6 (614196), caused by mutation in the PTPRO gene (600579); NPHS7 (615008), caused by mutation in the DGKE gene (601440); NPHS8 (615244), caused by mutation in the ARHGDIA gene (601925); NPHS9 (615573), caused by mutation in the COQ8B gene (615567); NPHS10 (615861), caused by mutation in the EMP2 gene (602334); NPHS11 (616730), caused by mutation in the NUP107 gene (607617); NPHS12 (616892), caused by mutation in the NUP93 gene (614351); NPHS13 (616893), caused by mutation in the NUP205 gene (614352); NPHS14 (617575), caused by mutation in the SGPL1 gene (603729); NPHS15 (617609), caused by mutation in the MAGI2 gene (606382); NPHS16 (617783), caused by mutation in the KANK2 gene (614610), NPHS17 (618176), caused by mutation in the NUP85 gene (170285); NPHS18 (618177), caused by mutation in the NUP133 gene (607613); NPHS19 (618178), caused by mutation in the NUP160 gene (607614); NPHS20 (301028), caused by mutation in the TBC1D8B gene (301027); and NPHS21 (618594) caused by mutation in the AVIL gene (613397). [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_4904"><div><strong>Focal segmental glomerulosclerosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>4904</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017668</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Segmental accumulation of scar tissue in individual (but not all) glomeruli.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/4904">Feature record</a> | <a href="/medgen?term=%22Focal%20segmental%20glomerulosclerosis%22%5BClinical%20Features%5D%20OR%204904%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_10976"><div><strong>Proteinuria</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>10976</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0033687</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Increased levels of protein in the urine.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/10976">Feature record</a> | <a href="/medgen?term=%22Proteinuria%22%5BClinical%20Features%5D%20OR%2010976%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_384526"><div><strong>Stage 5 chronic kidney disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>384526</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2316810</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A degree of kidney failure severe enough to require dialysis or kidney transplantation for survival characterized by a severe reduction in glomerular filtration rate (less than 15 ml/min/1.73 m2) and other manifestations including increased serum creatinine.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/384526">Feature record</a> | <a href="/medgen?term=%22Stage%205%20chronic%20kidney%20disease%22%5BClinical%20Features%5D%20OR%20384526%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_477530"><div><strong>Hyperechogenic kidneys</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>477530</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3275899</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An increase in amplitude of waves returned in ultrasonography of the kidney, which is generally displayed as increased brightness of the signal.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/477530">Feature record</a> | <a href="/medgen?term=%22Hyperechogenic%20kidneys%22%5BClinical%20Features%5D%20OR%20477530%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_813461"><div><strong>Reduced renal corticomedullary differentiation</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>813461</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3807131</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Reduced differentiation between renal cortex and medulla on diagnostic imaging.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/813461">Feature record</a> | <a href="/medgen?term=%22Reduced%20renal%20corticomedullary%20differentiation%22%5BClinical%20Features%5D%20OR%20813461%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_6969"><div><strong>Hypertensive disorder</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>6969</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0020538</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of chronic increased pressure in the systemic arterial system.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/6969">Feature record</a> | <a href="/medgen?term=%22Hypertensive%20disorder%22%5BClinical%20Features%5D%20OR%206969%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_416"><div><strong>Ascites</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>416</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0003962</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Accumulation of fluid in the peritoneal cavity (between the layers of the peritoneum that lines the abdomen).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/416">Feature record</a> | <a href="/medgen?term=%22Ascites%22%5BClinical%20Features%5D%20OR%20416%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_1526"><div><strong>Anemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1526</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0002871</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A reduction in erythrocytes volume or hemoglobin concentration.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1526">Feature record</a> | <a href="/medgen?term=%22Anemia%22%5BClinical%20Features%5D%20OR%201526%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_10805"><div><strong>Pleural effusion</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>10805</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0032227</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Pathologic Function</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of an excessive amount of fluid in the pleural cavity.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/10805">Feature record</a> | <a href="/medgen?term=%22Pleural%20effusion%22%5BClinical%20Features%5D%20OR%2010805%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_4451"><div><strong>Edema</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>4451</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0013604</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Pathologic Function</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An abnormal accumulation of fluid beneath the skin, or in one or more cavities of the body.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/4451">Feature record</a> | <a href="/medgen?term=%22Edema%22%5BClinical%20Features%5D%20OR%204451%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_5692"><div><strong>Hyperlipidemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5692</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0020473</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An elevated lipid concentration in the blood.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5692">Feature record</a> | <a href="/medgen?term=%22Hyperlipidemia%22%5BClinical%20Features%5D%20OR%205692%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_68694"><div><strong>Hypoalbuminemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>68694</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0239981</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Reduction in the concentration of albumin in the blood.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/68694">Feature record</a> | <a href="/medgen?term=%22Hypoalbuminemia%22%5BClinical%20Features%5D%20OR%2068694%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of blood and blood-forming tissues</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1526" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Anemia</a></span></li></ul></li><li><span class="TLline">Abnormality of metabolism/homeostasis</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_4451" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Edema</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_5692" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyperlipidemia</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_68694" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypoalbuminemia</a></span></li></ul></li><li><span class="TLline">Abnormality of the cardiovascular system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_6969" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypertensive disorder</a></span></li></ul></li><li><span class="TLline">Abnormality of the digestive system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_416" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ascites</a></span></li></ul></li><li><span class="TLline">Abnormality of the genitourinary system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_4904" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Focal segmental glomerulosclerosis</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_477530" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyperechogenic kidneys</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_10976" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Proteinuria</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_813461" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Reduced renal corticomedullary differentiation</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_384526" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Stage 5 chronic kidney disease</a></span></li></ul></li><li><span class="TLline">Abnormality of the respiratory system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_10805" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pleural effusion</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C4273714[DISCUI]&test_type=Clinical" ref="ncbi_uid=902527">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C4273714[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=902527">R</a></span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=902527" ref="ncbi_uid=902527">V</a></span></span><span class="TLline"><a href="/medgen/902527" ref="tree=GTR&ncbi_uid=902527&link_uid=902527" title="View MedGen record for 'Familial idiopathic steroid-resistant nephrotic syndrome'">Familial idiopathic steroid-resistant nephrotic syndrome</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=CN043612[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=432731">R</a></span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/432731" ref="tree=GTR&ncbi_uid=432731&link_uid=432731" title="View MedGen record for 'Hereditary Nephrotic Syndromes, Autosomal Dominant'">Hereditary Nephrotic Syndromes, Autosomal Dominant</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0017668[DISCUI]&test_type=Clinical" ref="ncbi_uid=4904">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C0017668[DISCUI]&test_type=Research" ref="ncbi_uid=4904">R</a></span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=4904" ref="ncbi_uid=4904">V</a></span></span><span class="TLline"><a href="/medgen/4904" ref="tree=GTR&ncbi_uid=4904&link_uid=4904" title="View MedGen record for 'Focal segmental glomerulosclerosis'">Focal segmental glomerulosclerosis</a></span><ul><li class="TLclosed"><span class="TLline"><a href="/medgen/1008296" ref="tree=GTR&ncbi_uid=1008296&link_uid=1008296" title="View MedGen record for 'Inherited focal segmental glomerulosclerosis'">Inherited focal segmental glomerulosclerosis</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C3151568[DISCUI]&test_type=Clinical" ref="ncbi_uid=462918">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C3151568[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=462918">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=462918" target="_blank" href="/omim/256370">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK556455/" ref="ncbi_uid=462918">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=462918" ref="ncbi_uid=462918">V</a></span></span><span class="TLline"><a href="/medgen/462918" ref="tree=GTR&ncbi_uid=462918&link_uid=462918" title="View MedGen record for 'Nephrotic syndrome, type 4'">Nephrotic syndrome, type 4</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=CN043613[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=432732">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=CN043613[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=432732">R</a></span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/432732" ref="tree=GTR&ncbi_uid=432732&link_uid=432732" title="View MedGen record for 'Hereditary Nephrotic Syndromes, Autosomal Recessive'">Hereditary Nephrotic Syndromes, Autosomal Recessive</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0403399[DISCUI]&test_type=Clinical" ref="ncbi_uid=98011">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C0403399[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=98011">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=98011" target="_blank" href="/omim/256300">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK573219/" ref="ncbi_uid=98011">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=98011" ref="ncbi_uid=98011">V</a></span></span><span class="TLline"><a href="/medgen/98011" ref="tree=GTR&ncbi_uid=98011&link_uid=98011" title="View MedGen record for 'Finnish congenital nephrotic syndrome'">Finnish congenital nephrotic syndrome</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1868672[DISCUI]&test_type=Clinical" ref="ncbi_uid=358380">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C1868672[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=358380">R</a></span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=358380" target="_blank" href="/omim/600995">O</a></span><span class="chiclet Gcolor" title="GeneReviews"><a target="_blank" href="/books/NBK573219/" ref="ncbi_uid=358380">G</a></span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=358380" ref="ncbi_uid=358380">V</a></span></span><span class="TLline"><a href="/medgen/358380" ref="tree=GTR&ncbi_uid=358380&link_uid=358380" title="View MedGen record for 'Nephrotic syndrome, type 2'">Nephrotic syndrome, type 2</a></span></li></ul></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/868444" ref="tree=MeSH" title="MedGen record for Abnormal nephron morphology">Abnormal nephron morphology</a></span><ul><li><span class="TLline"><a href="/medgen/1623650" ref="tree=MeSH" title="MedGen record for Abnormal renal corpuscle morphology">Abnormal renal corpuscle morphology</a></span><ul><li><span class="TLline"><a href="/medgen/871392" ref="tree=MeSH" title="MedGen record for Abnormal renal glomerulus morphology">Abnormal renal glomerulus morphology</a></span><ul><li><span class="TLline"><a href="/medgen/61248" ref="tree=MeSH" title="MedGen record for Glomerular sclerosis">Glomerular sclerosis</a></span><ul><li><span class="TLline"><a href="/medgen/4904" ref="tree=MeSH" title="MedGen record for Focal segmental glomerulosclerosis">Focal segmental glomerulosclerosis</a></span><ul><li><span class="TLline"><a href="/medgen/1008296" ref="tree=MeSH" title="MedGen record for Inherited focal segmental glomerulosclerosis">Inherited focal segmental glomerulosclerosis</a></span><ul><li><span class="matched_ds">Focal segmental glomerulosclerosis 1</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34556300">Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rovin BH,
|
||
Adler SG,
|
||
Barratt J,
|
||
Bridoux F,
|
||
Burdge KA,
|
||
Chan TM,
|
||
Cook HT,
|
||
Fervenza FC,
|
||
Gibson KL,
|
||
Glassock RJ,
|
||
Jayne DRW,
|
||
Jha V,
|
||
Liew A,
|
||
Liu ZH,
|
||
Mejía-Vilet JM,
|
||
Nester CM,
|
||
Radhakrishnan J,
|
||
Rave EM,
|
||
Reich HN,
|
||
Ronco P,
|
||
Sanders JF,
|
||
Sethi S,
|
||
Suzuki Y,
|
||
Tang SCW,
|
||
Tesar V,
|
||
Vivarelli M,
|
||
Wetzels JFM,
|
||
Lytvyn L,
|
||
Craig JC,
|
||
Tunnicliffe DJ,
|
||
Howell M,
|
||
Tonelli MA,
|
||
Cheung M,
|
||
Earley A,
|
||
Floege J</span><br />
|
||
<span class="medgenPMjournal">Kidney Int</span>
|
||
2021 Oct;100(4):753-779.
|
||
doi: 10.1016/j.kint.2021.05.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34556300" target="_blank">34556300</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28914167">Nephrotic syndrome in infants and children: pathophysiology and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Downie ML,
|
||
Gallibois C,
|
||
Parekh RS,
|
||
Noone DG</span><br />
|
||
<span class="medgenPMjournal">Paediatr Int Child Health</span>
|
||
2017 Nov;37(4):248-258.
|
||
Epub 2017 Sep 15
|
||
doi: 10.1080/20469047.2017.1374003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28914167" target="_blank">28914167</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26977832">Diagnosis and Management of Nephrotic Syndrome in Adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kodner C</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2016 Mar 15;93(6):479-85.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26977832" target="_blank">26977832</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(focal%20segmental%20glomerulosclerosis%201)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (334)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38664100">Recurrence of Glomerulonephritis After Kidney Transplantation - Experience of One Center from 2020 to 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wieliczko M,
|
||
Nazarewski S,
|
||
Gałązka Z,
|
||
Małyszko J</span><br />
|
||
<span class="medgenPMjournal">Transplant Proc</span>
|
||
2024 May;56(4):789-792.
|
||
Epub 2024 Apr 24
|
||
doi: 10.1016/j.transproceed.2024.03.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38664100" target="_blank">38664100</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35354140">New Onset Biopsy-Proven Nephropathies after COVID Vaccination.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fenoglio R,
|
||
Lalloni S,
|
||
Marchisio M,
|
||
Oddone V,
|
||
De Simone E,
|
||
Del Vecchio G,
|
||
Sciascia S,
|
||
Roccatello D</span><br />
|
||
<span class="medgenPMjournal">Am J Nephrol</span>
|
||
2022;53(4):325-330.
|
||
Epub 2022 Mar 30
|
||
doi: 10.1159/000523962.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35354140" target="_blank">35354140</a><a href="/pmc/articles/PMC9059008" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26154936">Epidemiology of biopsy-proven glomerulonephritis in Queensland adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jegatheesan D,
|
||
Nath K,
|
||
Reyaldeen R,
|
||
Sivasuthan G,
|
||
John GT,
|
||
Francis L,
|
||
Rajmokan M,
|
||
Ranganathan D</span><br />
|
||
<span class="medgenPMjournal">Nephrology (Carlton)</span>
|
||
2016 Jan;21(1):28-34.
|
||
doi: 10.1111/nep.12559.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26154936" target="_blank">26154936</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21733549">Acquired glomerular lesions in patients with Down syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Said SM,
|
||
Cornell LD,
|
||
Sethi S,
|
||
Fidler ME,
|
||
Al Masri O,
|
||
Marple J,
|
||
Nasr SH</span><br />
|
||
<span class="medgenPMjournal">Hum Pathol</span>
|
||
2012 Jan;43(1):81-8.
|
||
Epub 2011 Jul 5
|
||
doi: 10.1016/j.humpath.2011.04.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21733549" target="_blank">21733549</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9729649">Spontaneous cellulitis in adults with idiopathic nephrotic syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cheng YF,
|
||
Chuang FR,
|
||
Chen JB,
|
||
Liao SC,
|
||
Lam KK,
|
||
Hsu KT</span><br />
|
||
<span class="medgenPMjournal">Changgeng Yi Xue Za Zhi</span>
|
||
1998 Jun;21(2):158-64.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9729649" target="_blank">9729649</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Focal%20segmental%20glomerulosclerosis%201%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38664100">Recurrence of Glomerulonephritis After Kidney Transplantation - Experience of One Center from 2020 to 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wieliczko M,
|
||
Nazarewski S,
|
||
Gałązka Z,
|
||
Małyszko J</span><br />
|
||
<span class="medgenPMjournal">Transplant Proc</span>
|
||
2024 May;56(4):789-792.
|
||
Epub 2024 Apr 24
|
||
doi: 10.1016/j.transproceed.2024.03.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38664100" target="_blank">38664100</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35354140">New Onset Biopsy-Proven Nephropathies after COVID Vaccination.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fenoglio R,
|
||
Lalloni S,
|
||
Marchisio M,
|
||
Oddone V,
|
||
De Simone E,
|
||
Del Vecchio G,
|
||
Sciascia S,
|
||
Roccatello D</span><br />
|
||
<span class="medgenPMjournal">Am J Nephrol</span>
|
||
2022;53(4):325-330.
|
||
Epub 2022 Mar 30
|
||
doi: 10.1159/000523962.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35354140" target="_blank">35354140</a><a href="/pmc/articles/PMC9059008" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26154936">Epidemiology of biopsy-proven glomerulonephritis in Queensland adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jegatheesan D,
|
||
Nath K,
|
||
Reyaldeen R,
|
||
Sivasuthan G,
|
||
John GT,
|
||
Francis L,
|
||
Rajmokan M,
|
||
Ranganathan D</span><br />
|
||
<span class="medgenPMjournal">Nephrology (Carlton)</span>
|
||
2016 Jan;21(1):28-34.
|
||
doi: 10.1111/nep.12559.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26154936" target="_blank">26154936</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21068142">The incidence of primary glomerulonephritis worldwide: a systematic review of the literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McGrogan A,
|
||
Franssen CF,
|
||
de Vries CS</span><br />
|
||
<span class="medgenPMjournal">Nephrol Dial Transplant</span>
|
||
2011 Feb;26(2):414-30.
|
||
Epub 2010 Nov 10
|
||
doi: 10.1093/ndt/gfq665.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21068142" target="_blank">21068142</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2234252">Pattern of double glomerulopathies. A clinicopathologic study in nine nondiabetic patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Monga G,
|
||
Mazzucco G,
|
||
Barbiano di Belgiojoso G,
|
||
Confalonieri R,
|
||
Sacchi G,
|
||
Bertani T</span><br />
|
||
<span class="medgenPMjournal">Nephron</span>
|
||
1990;56(1):73-80.
|
||
doi: 10.1159/000186104.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2234252" target="_blank">2234252</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Focal%20segmental%20glomerulosclerosis%201%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (7)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38664100">Recurrence of Glomerulonephritis After Kidney Transplantation - Experience of One Center from 2020 to 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wieliczko M,
|
||
Nazarewski S,
|
||
Gałązka Z,
|
||
Małyszko J</span><br />
|
||
<span class="medgenPMjournal">Transplant Proc</span>
|
||
2024 May;56(4):789-792.
|
||
Epub 2024 Apr 24
|
||
doi: 10.1016/j.transproceed.2024.03.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38664100" target="_blank">38664100</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36869828">Postmortem Histopathologic Findings and SARS-CoV-2 Detection in Autopsy Kidneys of Patients With COVID-19: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mahjani M,
|
||
Parvin M,
|
||
Ghobadi S,
|
||
Jafari A,
|
||
Ahangar H,
|
||
Gohari S,
|
||
Gohari S</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Pathol</span>
|
||
2023 May 2;159(5):429-436.
|
||
doi: 10.1093/ajcp/aqad001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36869828" target="_blank">36869828</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35354140">New Onset Biopsy-Proven Nephropathies after COVID Vaccination.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fenoglio R,
|
||
Lalloni S,
|
||
Marchisio M,
|
||
Oddone V,
|
||
De Simone E,
|
||
Del Vecchio G,
|
||
Sciascia S,
|
||
Roccatello D</span><br />
|
||
<span class="medgenPMjournal">Am J Nephrol</span>
|
||
2022;53(4):325-330.
|
||
Epub 2022 Mar 30
|
||
doi: 10.1159/000523962.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35354140" target="_blank">35354140</a><a href="/pmc/articles/PMC9059008" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/14964454">Mycophenolate mofetil in children with multidrug-resistant nephrotic syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bayazit AK,
|
||
Noyan A,
|
||
Cengiz N,
|
||
Anarat A</span><br />
|
||
<span class="medgenPMjournal">Clin Nephrol</span>
|
||
2004 Jan;61(1):25-9.
|
||
doi: 10.5414/cnp61025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14964454" target="_blank">14964454</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6627762">Renal biopsy appearances in rheumatoid disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sellars L,
|
||
Siamopoulos K,
|
||
Wilkinson R,
|
||
Leohapand T,
|
||
Morley AR</span><br />
|
||
<span class="medgenPMjournal">Clin Nephrol</span>
|
||
1983 Sep;20(3):114-20.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6627762" target="_blank">6627762</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Focal%20segmental%20glomerulosclerosis%201%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38664100">Recurrence of Glomerulonephritis After Kidney Transplantation - Experience of One Center from 2020 to 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wieliczko M,
|
||
Nazarewski S,
|
||
Gałązka Z,
|
||
Małyszko J</span><br />
|
||
<span class="medgenPMjournal">Transplant Proc</span>
|
||
2024 May;56(4):789-792.
|
||
Epub 2024 Apr 24
|
||
doi: 10.1016/j.transproceed.2024.03.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38664100" target="_blank">38664100</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26154936">Epidemiology of biopsy-proven glomerulonephritis in Queensland adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jegatheesan D,
|
||
Nath K,
|
||
Reyaldeen R,
|
||
Sivasuthan G,
|
||
John GT,
|
||
Francis L,
|
||
Rajmokan M,
|
||
Ranganathan D</span><br />
|
||
<span class="medgenPMjournal">Nephrology (Carlton)</span>
|
||
2016 Jan;21(1):28-34.
|
||
doi: 10.1111/nep.12559.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26154936" target="_blank">26154936</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21733549">Acquired glomerular lesions in patients with Down syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Said SM,
|
||
Cornell LD,
|
||
Sethi S,
|
||
Fidler ME,
|
||
Al Masri O,
|
||
Marple J,
|
||
Nasr SH</span><br />
|
||
<span class="medgenPMjournal">Hum Pathol</span>
|
||
2012 Jan;43(1):81-8.
|
||
Epub 2011 Jul 5
|
||
doi: 10.1016/j.humpath.2011.04.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21733549" target="_blank">21733549</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21068142">The incidence of primary glomerulonephritis worldwide: a systematic review of the literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McGrogan A,
|
||
Franssen CF,
|
||
de Vries CS</span><br />
|
||
<span class="medgenPMjournal">Nephrol Dial Transplant</span>
|
||
2011 Feb;26(2):414-30.
|
||
Epub 2010 Nov 10
|
||
doi: 10.1093/ndt/gfq665.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21068142" target="_blank">21068142</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9890685">Renal diseases in ankylosing spondylitis: review of the literature illustrated by case reports.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Strobel ES,
|
||
Fritschka E</span><br />
|
||
<span class="medgenPMjournal">Clin Rheumatol</span>
|
||
1998;17(6):524-30.
|
||
doi: 10.1007/BF01451293.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9890685" target="_blank">9890685</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Focal%20segmental%20glomerulosclerosis%201%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38664100">Recurrence of Glomerulonephritis After Kidney Transplantation - Experience of One Center from 2020 to 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wieliczko M,
|
||
Nazarewski S,
|
||
Gałązka Z,
|
||
Małyszko J</span><br />
|
||
<span class="medgenPMjournal">Transplant Proc</span>
|
||
2024 May;56(4):789-792.
|
||
Epub 2024 Apr 24
|
||
doi: 10.1016/j.transproceed.2024.03.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38664100" target="_blank">38664100</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32479988">B-cell oligoclonal expansions in renal tissue of patients with immune-mediated glomerular disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kolovou K,
|
||
Laskari K,
|
||
Roumelioti M,
|
||
Tektonidou MG,
|
||
Panayiotidis P,
|
||
Boletis JN,
|
||
Marinaki S,
|
||
Sfikakis PP</span><br />
|
||
<span class="medgenPMjournal">Clin Immunol</span>
|
||
2020 Aug;217:108488.
|
||
Epub 2020 May 30
|
||
doi: 10.1016/j.clim.2020.108488.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32479988" target="_blank">32479988</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/14964454">Mycophenolate mofetil in children with multidrug-resistant nephrotic syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bayazit AK,
|
||
Noyan A,
|
||
Cengiz N,
|
||
Anarat A</span><br />
|
||
<span class="medgenPMjournal">Clin Nephrol</span>
|
||
2004 Jan;61(1):25-9.
|
||
doi: 10.5414/cnp61025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14964454" target="_blank">14964454</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Focal%20segmental%20glomerulosclerosis%201%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/36869828">Postmortem Histopathologic Findings and SARS-CoV-2 Detection in Autopsy Kidneys of Patients With COVID-19: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mahjani M,
|
||
Parvin M,
|
||
Ghobadi S,
|
||
Jafari A,
|
||
Ahangar H,
|
||
Gohari S,
|
||
Gohari S</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Pathol</span>
|
||
2023 May 2;159(5):429-436.
|
||
doi: 10.1093/ajcp/aqad001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36869828" target="_blank">36869828</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21068142">The incidence of primary glomerulonephritis worldwide: a systematic review of the literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McGrogan A,
|
||
Franssen CF,
|
||
de Vries CS</span><br />
|
||
<span class="medgenPMjournal">Nephrol Dial Transplant</span>
|
||
2011 Feb;26(2):414-30.
|
||
Epub 2010 Nov 10
|
||
doi: 10.1093/ndt/gfq665.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21068142" target="_blank">21068142</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Focal%20segmental%20glomerulosclerosis%201%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
||
<div class="portlet mgSection" id="ID_113">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_106">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C4551527%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (22)</a></li>
|
||
<li><a href="/gtr/tests?term=C4551527%5bDISCUI%5d&filter=method%3A2%5F29" target="_blank">Detection of homozygosity (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C4551527%5bDISCUI%5d&filter=method%3A2%5F17" target="_blank">Mutation scanning of the entire coding region (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C4551527%5bDISCUI%5d&test_type=Research" target="_blank">Research (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C4551527%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (33)</a></li>
|
||
<li><a href="/gtr/tests?term=C4551527%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (10)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C4551527%5bDISCUI%5d" target="_blank">See all (37)</a></total></li>
|
||
</ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_119">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=603278" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Focal%20segmental%20glomerulosclerosis%201" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_121">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(focal%20segmental%20glomerulosclerosis%201)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Focal%20segmental%20glomerulosclerosis%201%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_115">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=604638" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=81[geneid]" target="_blank">View ACTN4 variations in ClinVar</a></li><li><a href="/nuccore/163954917" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=603278" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_116">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="http://www.diseaseinfosearch.org/Focal+Segmental+Glomerulosclerosis/2890" target="_blank">Genetic Alliance</a></li><li><a href="https://www.malacards.org/card/focal_segmental_glomerulosclerosis_1" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Focal%20segmental%20glomerulosclerosis%201" target="_blank">MedlinePlus</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/15353/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
||
</div>
|
||
</div>
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Reviews</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Reviews" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pubmed/clinical?term=Focal%20segmental%20glomerulosclerosis%201" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed?term=Focal%20segmental%20glomerulosclerosis%201%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<!-- MedGen supplemental column ends here -->
|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
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|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=1636833" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=medgen_gene_diseases&from_uid=1636833" ref="log$=recordlinks">Gene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in NCBI Gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C4551527[DISCUI]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C4551527[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C4551527[DISCUI]&test_type=Research" ref="log$=recordlinks">GTR(Research)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Research tests in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/mesh?LinkName=medgen_mesh&from_uid=1636833" ref="log$=recordlinks">MeSH</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Medical Subject Headings</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim&from_uid=1636833" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related records in OMIM</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=medgen_omim_gene&from_uid=1636833" ref="log$=recordlinks">OMIM(Genes)</a>
|
||
<div class="brieflinkpop offscreen_noflow">OMIM records containing genes associated with phenotypes registered in MedGen</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=1636833" ref="log$=recordlinks">PMC Articles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in PubMed Central Links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&from_uid=1636833" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed_omim&from_uid=1636833" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Shutter"></a>
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<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
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