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<meta name="keywords" content="C4023512, disease or syndrome, myoclonic absence, myoclonic absence seizure, myoclonic absences, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Myoclonic absence seizure is a type of generalized non-motor (absence) seizure characterized by an interruption of ongoing activities, a blank stare and rhythmic three-per-second myoclonic movements, causing ratcheting abduction of the upper limbs leading to progressive arm elevation, and associated with 3 Hz generalized spike-wave discharges on the electroencephalogram. Duration is typically 10-60 s. Whilst impairment of consciousness may not be obvious the ILAE classified this seizure as a generalized non-motor seizure in 2017." /><meta name="robots" content="index,nofollow,noarchive" />
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ConceptID=C4023512
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Myoclonic absence seizure</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>869094</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4023512</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Myoclonic absence; Myoclonic absences</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Myoclonic absence seizure (1208629005)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0011150">HP:0011150</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Myoclonic absence seizure is a type of generalized non-motor (absence) seizure characterized by an interruption of ongoing activities, a blank stare and rhythmic three-per-second myoclonic movements, causing ratcheting abduction of the upper limbs leading to progressive arm elevation, and associated with 3 Hz generalized spike-wave discharges on the electroencephalogram. Duration is typically 10-60 s. Whilst impairment of consciousness may not be obvious the ILAE classified this seizure as a generalized non-motor seizure in 2017. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Myoclonic absence seizure</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/474891" ref="tree=MeSH" title="MedGen record for Congenital Systemic Disorder">Congenital Systemic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868417" ref="tree=MeSH" title="MedGen record for Abnormal nervous system physiology">Abnormal nervous system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/20693" ref="tree=MeSH" title="MedGen record for Seizure">Seizure</a></span><ul><li><span class="TLline"><a href="/medgen/1780546" ref="tree=MeSH" title="MedGen record for Non-motor seizure">Non-motor seizure</a></span><ul><li><span class="TLline"><a href="/medgen/1385688" ref="tree=MeSH" title="MedGen record for Generalized non-motor (absence) seizure">Generalized non-motor (absence) seizure</a></span><ul><li><span class="matched_ds">Myoclonic absence seizure</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
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|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_346552"><div><strong>Progressive encephalopathy with leukodystrophy due to DECR deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>346552</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1857252</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">2,4-Dienoyl-CoA reductase deficiency (DECRD) is a rare autosomal recessive inborn error of metabolism resulting in mitochondrial dysfunction due to impaired production of NADPH, which is an essential cofactor for several mitochondrial enzymes. Affected individuals have a variable phenotype: some may have severe neurologic symptoms and metabolic dysfunction beginning in early infancy, whereas others may present with more subtle features, such as childhood-onset optic atrophy or intermittent muscle weakness. The variable severity is putatively dependent on the effect of the mutation on the NADK2 enzyme. Biochemical analysis typically shows hyperlysinemia, due to defective activity of the mitochondrial NADP(H)-dependent enzyme AASS (605113), which is usually a benign finding. More severe cases have increased C10:2-carnitine levels, due to defective activity of the enzyme DECR (DECR1; 222745) (summary by Houten et al., 2014 and Pomerantz et al., 2018).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/346552">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_382611"><div><strong>Intellectual disability, autosomal dominant 5</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>382611</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2675473</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Mental or Behavioral Dysfunction</dd></dl></div></div></div>
|
||
<div class="spaceAbove">SYNGAP1-related intellectual disability (SYNGAP1-ID) is characterized by developmental delay (DD) or intellectual disability (ID) (100% of affected individuals), generalized epilepsy (~84%), and autism spectrum disorder (ASD) and other behavioral abnormalities (=50%). To date more than 50 individuals with SYNGAP1-ID have been reported. In the majority DD/ID was moderate to severe; in some it was mild. The epilepsy is generalized; a subset of individuals with epilepsy have myoclonic astatic epilepsy (Doose syndrome) or epilepsy with myoclonic absences. Behavioral abnormalities can include stereotypic behaviors (e.g., hand flapping, obsessions with certain objects) as well as poor social development. Feeding difficulties can be significant in some.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/382611">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1641343"><div><strong>Developmental delay and seizures with or without movement abnormalities</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1641343</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4693376</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">DEDSM is a neurodevelopmental disorder characterized by global developmental delay, variable intellectual disability, and early-onset seizures with a myoclonic component. Most patients have delayed motor development and show abnormal movements, including ataxia, dystonia, and tremor (summary by Hamdan et al., 2017).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1641343">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1684869"><div><strong>Epilepsy, idiopathic generalized, susceptibility to, 16</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1684869</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5231421</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1684869">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1740295"><div><strong>Intellectual developmental disorder with seizures and language delay</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1740295</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436574</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">SETD1B-related neurodevelopmental disorder (SETD1B-NDD) is characterized by developmental delay (mainly affecting speech and language), intellectual disability, seizures, autism spectrum disorder or autism-like behaviors, and additional behavioral concerns. Speech delay and/or language disorder has been reported in most affected individuals. Delay in gross motor skills and mild-to-moderate intellectual disability are common. Most affected individuals have seizures with variable onset and seizure type. Behavioral issues including hyperactivity, aggression, anxiety, and sleep disorders have been reported in approximately half of individuals. Less common features include ophthalmologic manifestations and feeding issues.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1740295">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1779648"><div><strong>Developmental and epileptic encephalopathy 6B</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1779648</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543353</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">SCN1A seizure disorders encompass a spectrum that ranges from simple febrile seizures and generalized epilepsy with febrile seizures plus (GEFS+) at the mild end to Dravet syndrome and intractable childhood epilepsy with generalized tonic-clonic seizures (ICE-GTC) at the severe end. Phenotypes with intractable seizures including Dravet syndrome are often associated with cognitive decline. Less commonly observed phenotypes include myoclonic astatic epilepsy (MAE), Lennox-Gastaut syndrome, infantile spasms, epilepsy with focal seizures, and vaccine-related encephalopathy and seizures. The phenotype of SCN1A seizure disorders can vary even within the same family.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1779648">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1779648" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Developmental and epileptic encephalopathy 6B</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1641343" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Developmental delay and seizures with or without movement abnormalities</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1684869" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Epilepsy, idiopathic generalized, susceptibility to, 16</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1740295" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual developmental disorder with seizures and language delay</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_382611" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual disability, autosomal dominant 5</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_346552" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Progressive encephalopathy with leukodystrophy due to DECR deficiency</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35490361">International consensus on diagnosis and management of Dravet syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wirrell EC,
|
||
Hood V,
|
||
Knupp KG,
|
||
Meskis MA,
|
||
Nabbout R,
|
||
Scheffer IE,
|
||
Wilmshurst J,
|
||
Sullivan J</span><br />
|
||
<span class="medgenPMjournal">Epilepsia</span>
|
||
2022 Jul;63(7):1761-1777.
|
||
Epub 2022 May 12
|
||
doi: 10.1111/epi.17274.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35490361" target="_blank">35490361</a><a href="/pmc/articles/PMC9543220" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34215386">Epilepsy: Epileptic Syndromes and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Katyayan A,
|
||
Diaz-Medina G</span><br />
|
||
<span class="medgenPMjournal">Neurol Clin</span>
|
||
2021 Aug;39(3):779-795.
|
||
doi: 10.1016/j.ncl.2021.04.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34215386" target="_blank">34215386</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33559102">Cannabidiol in the Treatment of Epilepsy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">von Wrede R,
|
||
Helmstaedter C,
|
||
Surges R</span><br />
|
||
<span class="medgenPMjournal">Clin Drug Investig</span>
|
||
2021 Mar;41(3):211-220.
|
||
Epub 2021 Feb 9
|
||
doi: 10.1007/s40261-021-01003-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33559102" target="_blank">33559102</a><a href="/pmc/articles/PMC7946683" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(myoclonic%20absence%20seizure)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (284)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37225432">Alzheimer Disease and Epilepsy: A Mendelian Randomization Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fang Y,
|
||
Si X,
|
||
Wang J,
|
||
Wang Z,
|
||
Chen Y,
|
||
Liu Y,
|
||
Yan Y,
|
||
Tian J,
|
||
Zhang B,
|
||
Pu J</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
2023 Jul 25;101(4):e399-e409.
|
||
Epub 2023 May 24
|
||
doi: 10.1212/WNL.0000000000207423.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37225432" target="_blank">37225432</a><a href="/pmc/articles/PMC10435057" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35490361">International consensus on diagnosis and management of Dravet syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wirrell EC,
|
||
Hood V,
|
||
Knupp KG,
|
||
Meskis MA,
|
||
Nabbout R,
|
||
Scheffer IE,
|
||
Wilmshurst J,
|
||
Sullivan J</span><br />
|
||
<span class="medgenPMjournal">Epilepsia</span>
|
||
2022 Jul;63(7):1761-1777.
|
||
Epub 2022 May 12
|
||
doi: 10.1111/epi.17274.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35490361" target="_blank">35490361</a><a href="/pmc/articles/PMC9543220" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33559102">Cannabidiol in the Treatment of Epilepsy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">von Wrede R,
|
||
Helmstaedter C,
|
||
Surges R</span><br />
|
||
<span class="medgenPMjournal">Clin Drug Investig</span>
|
||
2021 Mar;41(3):211-220.
|
||
Epub 2021 Feb 9
|
||
doi: 10.1007/s40261-021-01003-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33559102" target="_blank">33559102</a><a href="/pmc/articles/PMC7946683" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28538134">Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Devinsky O,
|
||
Cross JH,
|
||
Laux L,
|
||
Marsh E,
|
||
Miller I,
|
||
Nabbout R,
|
||
Scheffer IE,
|
||
Thiele EA,
|
||
Wright S;
|
||
Cannabidiol in Dravet Syndrome Study Group</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2017 May 25;376(21):2011-2020.
|
||
doi: 10.1056/NEJMoa1611618.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28538134" target="_blank">28538134</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16022579">Stiripentol.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chiron C</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Investig Drugs</span>
|
||
2005 Jul;14(7):905-11.
|
||
doi: 10.1517/13543784.14.7.905.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16022579" target="_blank">16022579</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myoclonic%20absence%20seizure%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1382)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37225432">Alzheimer Disease and Epilepsy: A Mendelian Randomization Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fang Y,
|
||
Si X,
|
||
Wang J,
|
||
Wang Z,
|
||
Chen Y,
|
||
Liu Y,
|
||
Yan Y,
|
||
Tian J,
|
||
Zhang B,
|
||
Pu J</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
2023 Jul 25;101(4):e399-e409.
|
||
Epub 2023 May 24
|
||
doi: 10.1212/WNL.0000000000207423.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37225432" target="_blank">37225432</a><a href="/pmc/articles/PMC10435057" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35503716">ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hirsch E,
|
||
French J,
|
||
Scheffer IE,
|
||
Bogacz A,
|
||
Alsaadi T,
|
||
Sperling MR,
|
||
Abdulla F,
|
||
Zuberi SM,
|
||
Trinka E,
|
||
Specchio N,
|
||
Somerville E,
|
||
Samia P,
|
||
Riney K,
|
||
Nabbout R,
|
||
Jain S,
|
||
Wilmshurst JM,
|
||
Auvin S,
|
||
Wiebe S,
|
||
Perucca E,
|
||
Moshé SL,
|
||
Tinuper P,
|
||
Wirrell EC</span><br />
|
||
<span class="medgenPMjournal">Epilepsia</span>
|
||
2022 Jun;63(6):1475-1499.
|
||
Epub 2022 May 3
|
||
doi: 10.1111/epi.17236.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35503716" target="_blank">35503716</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35490361">International consensus on diagnosis and management of Dravet syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wirrell EC,
|
||
Hood V,
|
||
Knupp KG,
|
||
Meskis MA,
|
||
Nabbout R,
|
||
Scheffer IE,
|
||
Wilmshurst J,
|
||
Sullivan J</span><br />
|
||
<span class="medgenPMjournal">Epilepsia</span>
|
||
2022 Jul;63(7):1761-1777.
|
||
Epub 2022 May 12
|
||
doi: 10.1111/epi.17274.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35490361" target="_blank">35490361</a><a href="/pmc/articles/PMC9543220" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33096746">Genetic Landscape of Common Epilepsies: Advancing towards Precision in Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Thakran S,
|
||
Guin D,
|
||
Singh P,
|
||
Singh P,
|
||
Kukal S,
|
||
Rawat C,
|
||
Yadav S,
|
||
Kushwaha SS,
|
||
Srivastava AK,
|
||
Hasija Y,
|
||
Saso L,
|
||
Ramachandran S,
|
||
Kukreti R</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2020 Oct 21;21(20)
|
||
doi: 10.3390/ijms21207784.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33096746" target="_blank">33096746</a><a href="/pmc/articles/PMC7589654" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28276060">Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fisher RS,
|
||
Cross JH,
|
||
French JA,
|
||
Higurashi N,
|
||
Hirsch E,
|
||
Jansen FE,
|
||
Lagae L,
|
||
Moshé SL,
|
||
Peltola J,
|
||
Roulet Perez E,
|
||
Scheffer IE,
|
||
Zuberi SM</span><br />
|
||
<span class="medgenPMjournal">Epilepsia</span>
|
||
2017 Apr;58(4):522-530.
|
||
Epub 2017 Mar 8
|
||
doi: 10.1111/epi.13670.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28276060" target="_blank">28276060</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myoclonic%20absence%20seizure%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1789)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37225432">Alzheimer Disease and Epilepsy: A Mendelian Randomization Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fang Y,
|
||
Si X,
|
||
Wang J,
|
||
Wang Z,
|
||
Chen Y,
|
||
Liu Y,
|
||
Yan Y,
|
||
Tian J,
|
||
Zhang B,
|
||
Pu J</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
2023 Jul 25;101(4):e399-e409.
|
||
Epub 2023 May 24
|
||
doi: 10.1212/WNL.0000000000207423.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37225432" target="_blank">37225432</a><a href="/pmc/articles/PMC10435057" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36762638">Recent advances in pharmacotherapy for epilepsy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pong AW,
|
||
Xu KJ,
|
||
Klein P</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Neurol</span>
|
||
2023 Apr 1;36(2):77-85.
|
||
Epub 2023 Feb 10
|
||
doi: 10.1097/WCO.0000000000001144.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36762638" target="_blank">36762638</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33395108">Dravet syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lagae L</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Neurol</span>
|
||
2021 Apr 1;34(2):213-218.
|
||
doi: 10.1097/WCO.0000000000000902.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33395108" target="_blank">33395108</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33332006">Cannabidiol Therapy for Refractory Epilepsy and Seizure Disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Golub V,
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<div class="nl"><a target="_blank" href="/pubmed/32893075">Epilepsy in Angelman syndrome: A scoping review.</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/32893075" target="_blank">32893075</a><a href="/pmc/articles/PMC7688500" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myoclonic%20absence%20seizure%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1408)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37225432">Alzheimer Disease and Epilepsy: A Mendelian Randomization Study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Fang Y,
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Chen Y,
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Liu Y,
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<span class="medgenPMjournal">Epilepsia</span>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hirsch E,
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French J,
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Scheffer IE,
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Bogacz A,
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Sperling MR,
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Trinka E,
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Specchio N,
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Somerville E,
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Samia P,
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Riney K,
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Nabbout R,
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Jain S,
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Wilmshurst JM,
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Auvin S,
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Wiebe S,
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<span class="medgenPMjournal">Epilepsia</span>
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2022 Jun;63(6):1475-1499.
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<span class="bold">PMID: </span><a href="/pubmed/35503716" target="_blank">35503716</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33395108">Dravet syndrome.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lagae L</span><br />
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<span class="medgenPMjournal">Curr Opin Neurol</span>
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2021 Apr 1;34(2):213-218.
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<span class="bold">PMID: </span><a href="/pubmed/33395108" target="_blank">33395108</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29137682">Cefepime-induced neurotoxicity: a systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Payne LE,
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Gagnon DJ,
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Riker RR,
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Seder DB,
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Glisic EK,
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<span class="medgenPMjournal">Crit Care</span>
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<span class="bold">PMID: </span><a href="/pubmed/29137682" target="_blank">29137682</a><a href="/pmc/articles/PMC5686900" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myoclonic%20absence%20seizure%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (970)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37467479">SCN1A-deficient excitatory neuronal networks display mutation-specific phenotypes.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">van Hugte EJH,
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Lewerissa EI,
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Wu KM,
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Scheefhals N,
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van Voorst TW,
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Keller JM,
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Frega M,
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Schubert D,
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Schelhaas HJ,
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van Bokhoven H,
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Nadif Kasri N</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/37467479" target="_blank">37467479</a><a href="/pmc/articles/PMC10689919" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
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||
<div class="nl"><a target="_blank" href="/pubmed/37316680">Fenfluramine: A Review in Dravet and Lennox-Gastaut Syndromes.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Frampton JE</span><br />
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2023 Jul;83(10):923-934.
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doi: 10.1007/s40265-023-01881-w.
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<span class="bold">PMID: </span><a href="/pubmed/37316680" target="_blank">37316680</a><a href="/pmc/articles/PMC10310619" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37225432">Alzheimer Disease and Epilepsy: A Mendelian Randomization Study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Fang Y,
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Si X,
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Wang J,
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Wang Z,
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Chen Y,
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Liu Y,
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Yan Y,
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Tian J,
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Zhang B,
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Pu J</span><br />
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<span class="medgenPMjournal">Neurology</span>
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2023 Jul 25;101(4):e399-e409.
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Epub 2023 May 24
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doi: 10.1212/WNL.0000000000207423.
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<span class="bold">PMID: </span><a href="/pubmed/37225432" target="_blank">37225432</a><a href="/pmc/articles/PMC10435057" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33754312">Highly Purified Cannabidiol for Epilepsy Treatment: A Systematic Review of Epileptic Conditions Beyond Dravet Syndrome and Lennox-Gastaut Syndrome.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lattanzi S,
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Trinka E,
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Striano P,
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Rocchi C,
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Salvemini S,
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Silvestrini M,
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Brigo F</span><br />
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<span class="medgenPMjournal">CNS Drugs</span>
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2021 Mar;35(3):265-281.
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Epub 2021 Mar 22
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doi: 10.1007/s40263-021-00807-y.
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<span class="bold">PMID: </span><a href="/pubmed/33754312" target="_blank">33754312</a><a href="/pmc/articles/PMC8005394" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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||
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||
<div class="nl"><a target="_blank" href="/pubmed/33096746">Genetic Landscape of Common Epilepsies: Advancing towards Precision in Treatment.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Thakran S,
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Guin D,
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Singh P,
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Singh P,
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Kukal S,
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Rawat C,
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Yadav S,
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Kushwaha SS,
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Srivastava AK,
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Hasija Y,
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Saso L,
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Ramachandran S,
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Kukreti R</span><br />
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<span class="medgenPMjournal">Int J Mol Sci</span>
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2020 Oct 21;21(20)
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doi: 10.3390/ijms21207784.
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<span class="bold">PMID: </span><a href="/pubmed/33096746" target="_blank">33096746</a><a href="/pmc/articles/PMC7589654" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myoclonic%20absence%20seizure%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (995)</a></div></div>
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||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37378757">Antiseizure medications for idiopathic generalized epilepsies: a systematic review and network meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Chu H,
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Zhang X,
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Shi J,
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Zhou Z,
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Yang X</span><br />
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<span class="medgenPMjournal">J Neurol</span>
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||
2023 Oct;270(10):4713-4728.
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||
Epub 2023 Jun 28
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||
doi: 10.1007/s00415-023-11834-8.
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||
<span class="bold">PMID: </span><a href="/pubmed/37378757" target="_blank">37378757</a><a href="/pmc/articles/PMC10511599" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36206805">Clinical efficacy and safety of cannabidiol for pediatric refractory epilepsy indications: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Talwar A,
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Estes E,
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Aparasu R,
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Reddy DS</span><br />
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<span class="medgenPMjournal">Exp Neurol</span>
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2023 Jan;359:114238.
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||
Epub 2022 Oct 4
|
||
doi: 10.1016/j.expneurol.2022.114238.
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||
<span class="bold">PMID: </span><a href="/pubmed/36206805" target="_blank">36206805</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34873203">Efficacy and safety of medical cannabinoids in children: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Treves N,
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||
Mor N,
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Allegaert K,
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Bassalov H,
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Berkovitch M,
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Stolar OE,
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Matok I</span><br />
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<span class="medgenPMjournal">Sci Rep</span>
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2021 Dec 6;11(1):23462.
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||
doi: 10.1038/s41598-021-02770-6.
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<span class="bold">PMID: </span><a href="/pubmed/34873203" target="_blank">34873203</a><a href="/pmc/articles/PMC8648720" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30390221">Efficacy and Safety of Cannabidiol in Epilepsy: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lattanzi S,
|
||
Brigo F,
|
||
Trinka E,
|
||
Zaccara G,
|
||
Cagnetti C,
|
||
Del Giovane C,
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||
Silvestrini M</span><br />
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<span class="medgenPMjournal">Drugs</span>
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2018 Nov;78(17):1791-1804.
|
||
doi: 10.1007/s40265-018-0992-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30390221" target="_blank">30390221</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29137682">Cefepime-induced neurotoxicity: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Payne LE,
|
||
Gagnon DJ,
|
||
Riker RR,
|
||
Seder DB,
|
||
Glisic EK,
|
||
Morris JG,
|
||
Fraser GL</span><br />
|
||
<span class="medgenPMjournal">Crit Care</span>
|
||
2017 Nov 14;21(1):276.
|
||
doi: 10.1186/s13054-017-1856-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29137682" target="_blank">29137682</a><a href="/pmc/articles/PMC5686900" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myoclonic%20absence%20seizure%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (57)</a></div></div>
|
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|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(myoclonic%20absence%20seizure)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Myoclonic%20absence%20seizure%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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