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<meta name="keywords" content="C3281288, corin, corin preeclampsia, disease or syndrome, pee5, preeclampsia caused by mutation in corin, preeclampsia/eclampsia 5, preeclampsia/eclampsia type 5, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Preeclampsia, which along with chronic hypertension and gestational hypertension comprise the hypertensive disorders of pregnancy, is characterized by new hypertension (blood pressure 140/90 or greater) presenting after 20 weeks' gestation with clinically relevant proteinuria. Preeclampsia is 1 of the top 4 causes of maternal mortality and morbidity worldwide (summary by Payne et al., 2011). For a general phenotypic description and a discussion of genetic heterogeneity of preeclampsia/eclampsia, see PEE1 (189800)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=482918
|
||
ConceptID=C3281288
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Preeclampsia/eclampsia 5<span class="h1sub">(PEE5)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>482918</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C3281288</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>PEE5</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="CORIN - ID: 10699 - NCBI Gene" href="/gene/10699" class="medgenPMinfo">CORIN</a> (4p12)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0013817" target="_blank">MONDO:0013817</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/614595" target="_blank">614595</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Preeclampsia, which along with chronic hypertension and gestational hypertension comprise the hypertensive disorders of pregnancy, is characterized by new hypertension (blood pressure 140/90 or greater) presenting after 20 weeks' gestation with clinically relevant proteinuria. Preeclampsia is 1 of the top 4 causes of maternal mortality and morbidity worldwide (summary by Payne et al., 2011). For a general phenotypic description and a discussion of genetic heterogeneity of preeclampsia/eclampsia, see PEE1 (189800). [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
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<div class="portlet mgSection" id="ID_117">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Additional_description">Additional description</h1><a sid="117" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><div class="mgSection"><strong>From MedlinePlus Genetics</strong><br />Preeclampsia is a complication of pregnancy in which affected women develop high blood pressure (hypertension); they can also have abnormally high levels of protein in their urine (proteinuria). This condition usually occurs in the last few months of pregnancy and often requires early delivery of the infant. However, this condition can also appear shortly after giving birth (postpartum preeclampsia).<br /><br />Women who have had preeclampsia have approximately twice the lifetime risk of heart disease and stroke than do women in the general population. Researchers suggest that preeclampsia, heart disease, and stroke may share common risk factors. Women who have diseases such as obesity, hypertension, heart disease, diabetes, or kidney disease before they become pregnant have an increased risk of developing preeclampsia. Preeclampsia is most likely to occur in a woman's first pregnancy, although it can occur in subsequent pregnancies, particularly in women with other health conditions.<br /><br />Many women with mild preeclampsia do not feel ill, and the condition is often first detected through blood pressure and urine testing in their doctor's office. In addition to hypertension and proteinuria, signs and symptoms of preeclampsia can include excessive swelling (edema) of the face or hands and a weight gain of more than 3 to 5 pounds in a week due to fluid retention. Affected women may also experience headaches, dizziness, irritability, shortness of breath, a decrease in urination, upper abdominal pain, and nausea or vomiting. Vision changes may develop, including flashing lights or spots, increased sensitivity to light (photophobia), blurry vision, or temporary blindness.<br /><br />In many cases, symptoms of preeclampsia go away within a few days after the baby is born. In severe cases, however, preeclampsia can damage the mother's organs, such as the heart, liver, and kidneys, and can lead to life-threatening complications. Extremely high blood pressure in the mother can cause bleeding in the brain (hemorrhagic stroke). The effects of high blood pressure on the brain (hypertensive encephalopathy) may also result in seizures. If seizures occur, the condition is considered to have worsened to eclampsia, which can result in coma. About 1 in 200 women with untreated preeclampsia develop eclampsia. Eclampsia can also develop without any obvious signs of preeclampsia.<br /><br />Between 10 and 20 percent of women with severe preeclampsia develop another potentially life-threatening complication called HELLP syndrome. HELLP stands for hemolysis (premature red blood cell breakdown), elevated liver enzyme levels, and low platelets (cells involved in blood clotting), which are the key features of this condition.<br /><br />Severe preeclampsia can also affect the fetus, with impairment of blood and oxygen flow leading to growth problems or stillbirth. Infants delivered early due to preeclampsia may have complications associated with prematurity, such as breathing problems caused by underdeveloped lungs. <a target="_blank" href="https://medlineplus.gov/genetics/condition/preeclampsia">https://medlineplus.gov/genetics/condition/preeclampsia</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/25840271">Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Erez O,
|
||
Mastrolia SA,
|
||
Thachil J</span><br />
|
||
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
|
||
2015 Oct;213(4):452-63.
|
||
Epub 2015 Mar 31
|
||
doi: 10.1016/j.ajog.2015.03.054.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25840271" target="_blank">25840271</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18814997">Postpartum preeclampsia: emergency department presentation and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yancey LM,
|
||
Withers E,
|
||
Bakes K,
|
||
Abbott J</span><br />
|
||
<span class="medgenPMjournal">J Emerg Med</span>
|
||
2011 Apr;40(4):380-4.
|
||
Epub 2008 Sep 23
|
||
doi: 10.1016/j.jemermed.2008.02.056.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18814997" target="_blank">18814997</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19019323">Diagnosis and management of atypical preeclampsia-eclampsia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sibai BM,
|
||
Stella CL</span><br />
|
||
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
|
||
2009 May;200(5):481.e1-7.
|
||
Epub 2008 Nov 18
|
||
doi: 10.1016/j.ajog.2008.07.048.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19019323" target="_blank">19019323</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(preeclampsia%2Feclampsia%205)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (10)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng133" target="_blank">UK NICE guideline (NG133), Hypertension in pregnancy: diagnosis and management, 2023</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37144983">Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Simmons D,
|
||
Immanuel J,
|
||
Hague WM,
|
||
Teede H,
|
||
Nolan CJ,
|
||
Peek MJ,
|
||
Flack JR,
|
||
McLean M,
|
||
Wong V,
|
||
Hibbert E,
|
||
Kautzky-Willer A,
|
||
Harreiter J,
|
||
Backman H,
|
||
Gianatti E,
|
||
Sweeting A,
|
||
Mohan V,
|
||
Enticott J,
|
||
Cheung NW;
|
||
TOBOGM Research Group</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2023 Jun 8;388(23):2132-2144.
|
||
Epub 2023 May 5
|
||
doi: 10.1056/NEJMoa2214956.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37144983" target="_blank">37144983</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33885740">Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Villar J,
|
||
Ariff S,
|
||
Gunier RB,
|
||
Thiruvengadam R,
|
||
Rauch S,
|
||
Kholin A,
|
||
Roggero P,
|
||
Prefumo F,
|
||
do Vale MS,
|
||
Cardona-Perez JA,
|
||
Maiz N,
|
||
Cetin I,
|
||
Savasi V,
|
||
Deruelle P,
|
||
Easter SR,
|
||
Sichitiu J,
|
||
Soto Conti CP,
|
||
Ernawati E,
|
||
Mhatre M,
|
||
Teji JS,
|
||
Liu B,
|
||
Capelli C,
|
||
Oberto M,
|
||
Salazar L,
|
||
Gravett MG,
|
||
Cavoretto PI,
|
||
Nachinab VB,
|
||
Galadanci H,
|
||
Oros D,
|
||
Ayede AI,
|
||
Sentilhes L,
|
||
Bako B,
|
||
Savorani M,
|
||
Cena H,
|
||
García-May PK,
|
||
Etuk S,
|
||
Casale R,
|
||
Abd-Elsalam S,
|
||
Ikenoue S,
|
||
Aminu MB,
|
||
Vecciarelli C,
|
||
Duro EA,
|
||
Usman MA,
|
||
John-Akinola Y,
|
||
Nieto R,
|
||
Ferrazi E,
|
||
Bhutta ZA,
|
||
Langer A,
|
||
Kennedy SH,
|
||
Papageorghiou AT</span><br />
|
||
<span class="medgenPMjournal">JAMA Pediatr</span>
|
||
2021 Aug 1;175(8):817-826.
|
||
doi: 10.1001/jamapediatrics.2021.1050.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33885740" target="_blank">33885740</a><a href="/pmc/articles/PMC8063132" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31838502">Associations Between Maternal Thyroid Function in Pregnancy and Obstetric and Perinatal Outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee SY,
|
||
Cabral HJ,
|
||
Aschengrau A,
|
||
Pearce EN</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2020 May 1;105(5):e2015-23.
|
||
doi: 10.1210/clinem/dgz275.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31838502" target="_blank">31838502</a><a href="/pmc/articles/PMC7089848" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31401877">Randomized Interventional Study on Prediction of Preeclampsia/Eclampsia in Women With Suspected Preeclampsia: INSPIRE.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cerdeira AS,
|
||
O'Sullivan J,
|
||
Ohuma EO,
|
||
Harrington D,
|
||
Szafranski P,
|
||
Black R,
|
||
Mackillop L,
|
||
Impey L,
|
||
Greenwood C,
|
||
James T,
|
||
Smith I,
|
||
Papageorghiou AT,
|
||
Knight M,
|
||
Vatish M</span><br />
|
||
<span class="medgenPMjournal">Hypertension</span>
|
||
2019 Oct;74(4):983-990.
|
||
Epub 2019 Aug 12
|
||
doi: 10.1161/HYPERTENSIONAHA.119.12739.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31401877" target="_blank">31401877</a><a href="/pmc/articles/PMC6756298" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24503673">Guidelines for the prevention of stroke in women: a statement for healthcare professionals from the American Heart Association/American Stroke Association.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bushnell C,
|
||
McCullough LD,
|
||
Awad IA,
|
||
Chireau MV,
|
||
Fedder WN,
|
||
Furie KL,
|
||
Howard VJ,
|
||
Lichtman JH,
|
||
Lisabeth LD,
|
||
Piña IL,
|
||
Reeves MJ,
|
||
Rexrode KM,
|
||
Saposnik G,
|
||
Singh V,
|
||
Towfighi A,
|
||
Vaccarino V,
|
||
Walters MR;
|
||
American Heart Association Stroke Council;
|
||
Council on Cardiovascular and Stroke Nursing;
|
||
Council on Clinical Cardiology;
|
||
Council on Epidemiology and Prevention;
|
||
Council for High Blood Pressure Research</span><br />
|
||
<span class="medgenPMjournal">Stroke</span>
|
||
2014 May;45(5):1545-88.
|
||
Epub 2014 Feb 6
|
||
doi: 10.1161/01.str.0000442009.06663.48.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24503673" target="_blank">24503673</a><a href="/pmc/articles/PMC10152977" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%2Feclampsia%205%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (274)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37144983">Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Simmons D,
|
||
Immanuel J,
|
||
Hague WM,
|
||
Teede H,
|
||
Nolan CJ,
|
||
Peek MJ,
|
||
Flack JR,
|
||
McLean M,
|
||
Wong V,
|
||
Hibbert E,
|
||
Kautzky-Willer A,
|
||
Harreiter J,
|
||
Backman H,
|
||
Gianatti E,
|
||
Sweeting A,
|
||
Mohan V,
|
||
Enticott J,
|
||
Cheung NW;
|
||
TOBOGM Research Group</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2023 Jun 8;388(23):2132-2144.
|
||
Epub 2023 May 5
|
||
doi: 10.1056/NEJMoa2214956.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37144983" target="_blank">37144983</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33885740">Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Villar J,
|
||
Ariff S,
|
||
Gunier RB,
|
||
Thiruvengadam R,
|
||
Rauch S,
|
||
Kholin A,
|
||
Roggero P,
|
||
Prefumo F,
|
||
do Vale MS,
|
||
Cardona-Perez JA,
|
||
Maiz N,
|
||
Cetin I,
|
||
Savasi V,
|
||
Deruelle P,
|
||
Easter SR,
|
||
Sichitiu J,
|
||
Soto Conti CP,
|
||
Ernawati E,
|
||
Mhatre M,
|
||
Teji JS,
|
||
Liu B,
|
||
Capelli C,
|
||
Oberto M,
|
||
Salazar L,
|
||
Gravett MG,
|
||
Cavoretto PI,
|
||
Nachinab VB,
|
||
Galadanci H,
|
||
Oros D,
|
||
Ayede AI,
|
||
Sentilhes L,
|
||
Bako B,
|
||
Savorani M,
|
||
Cena H,
|
||
García-May PK,
|
||
Etuk S,
|
||
Casale R,
|
||
Abd-Elsalam S,
|
||
Ikenoue S,
|
||
Aminu MB,
|
||
Vecciarelli C,
|
||
Duro EA,
|
||
Usman MA,
|
||
John-Akinola Y,
|
||
Nieto R,
|
||
Ferrazi E,
|
||
Bhutta ZA,
|
||
Langer A,
|
||
Kennedy SH,
|
||
Papageorghiou AT</span><br />
|
||
<span class="medgenPMjournal">JAMA Pediatr</span>
|
||
2021 Aug 1;175(8):817-826.
|
||
doi: 10.1001/jamapediatrics.2021.1050.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33885740" target="_blank">33885740</a><a href="/pmc/articles/PMC8063132" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31401877">Randomized Interventional Study on Prediction of Preeclampsia/Eclampsia in Women With Suspected Preeclampsia: INSPIRE.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cerdeira AS,
|
||
O'Sullivan J,
|
||
Ohuma EO,
|
||
Harrington D,
|
||
Szafranski P,
|
||
Black R,
|
||
Mackillop L,
|
||
Impey L,
|
||
Greenwood C,
|
||
James T,
|
||
Smith I,
|
||
Papageorghiou AT,
|
||
Knight M,
|
||
Vatish M</span><br />
|
||
<span class="medgenPMjournal">Hypertension</span>
|
||
2019 Oct;74(4):983-990.
|
||
Epub 2019 Aug 12
|
||
doi: 10.1161/HYPERTENSIONAHA.119.12739.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31401877" target="_blank">31401877</a><a href="/pmc/articles/PMC6756298" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27562782">Imaging of Headache in Pregnancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Skliut M,
|
||
Jamieson DG</span><br />
|
||
<span class="medgenPMjournal">Curr Pain Headache Rep</span>
|
||
2016 Oct;20(10):56.
|
||
doi: 10.1007/s11916-016-0585-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27562782" target="_blank">27562782</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19019323">Diagnosis and management of atypical preeclampsia-eclampsia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sibai BM,
|
||
Stella CL</span><br />
|
||
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
|
||
2009 May;200(5):481.e1-7.
|
||
Epub 2008 Nov 18
|
||
doi: 10.1016/j.ajog.2008.07.048.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19019323" target="_blank">19019323</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%2Feclampsia%205%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (123)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37144983">Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Simmons D,
|
||
Immanuel J,
|
||
Hague WM,
|
||
Teede H,
|
||
Nolan CJ,
|
||
Peek MJ,
|
||
Flack JR,
|
||
McLean M,
|
||
Wong V,
|
||
Hibbert E,
|
||
Kautzky-Willer A,
|
||
Harreiter J,
|
||
Backman H,
|
||
Gianatti E,
|
||
Sweeting A,
|
||
Mohan V,
|
||
Enticott J,
|
||
Cheung NW;
|
||
TOBOGM Research Group</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2023 Jun 8;388(23):2132-2144.
|
||
Epub 2023 May 5
|
||
doi: 10.1056/NEJMoa2214956.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37144983" target="_blank">37144983</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32813750">Systematic and meta-analysis of factors associated with preeclampsia and eclampsia in sub-Saharan Africa.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Meazaw MW,
|
||
Chojenta C,
|
||
Muluneh MD,
|
||
Loxton D</span><br />
|
||
<span class="medgenPMjournal">PLoS One</span>
|
||
2020;15(8):e0237600.
|
||
Epub 2020 Aug 19
|
||
doi: 10.1371/journal.pone.0237600.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32813750" target="_blank">32813750</a><a href="/pmc/articles/PMC7437916" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31401877">Randomized Interventional Study on Prediction of Preeclampsia/Eclampsia in Women With Suspected Preeclampsia: INSPIRE.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cerdeira AS,
|
||
O'Sullivan J,
|
||
Ohuma EO,
|
||
Harrington D,
|
||
Szafranski P,
|
||
Black R,
|
||
Mackillop L,
|
||
Impey L,
|
||
Greenwood C,
|
||
James T,
|
||
Smith I,
|
||
Papageorghiou AT,
|
||
Knight M,
|
||
Vatish M</span><br />
|
||
<span class="medgenPMjournal">Hypertension</span>
|
||
2019 Oct;74(4):983-990.
|
||
Epub 2019 Aug 12
|
||
doi: 10.1161/HYPERTENSIONAHA.119.12739.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31401877" target="_blank">31401877</a><a href="/pmc/articles/PMC6756298" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
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<div class="portlet_content ln"><span class="medgenPMauthor">Mugo M,
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<div class="nl"><a target="_blank" href="/pubmed/2288560">Magnesium sulfate is the ideal anticonvulsant in preeclampsia-eclampsia.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%2Feclampsia%205%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (82)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/32813750">Systematic and meta-analysis of factors associated with preeclampsia and eclampsia in sub-Saharan Africa.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Meazaw MW,
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Chojenta C,
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Muluneh MD,
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Loxton D</span><br />
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Epub 2020 Aug 19
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<span class="bold">PMID: </span><a href="/pubmed/32813750" target="_blank">32813750</a><a href="/pmc/articles/PMC7437916" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31401877">Randomized Interventional Study on Prediction of Preeclampsia/Eclampsia in Women With Suspected Preeclampsia: INSPIRE.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Cerdeira AS,
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O'Sullivan J,
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Ohuma EO,
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Harrington D,
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Szafranski P,
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Black R,
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Mackillop L,
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Impey L,
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Greenwood C,
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James T,
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Smith I,
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Papageorghiou AT,
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Knight M,
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Vatish M</span><br />
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2019 Oct;74(4):983-990.
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Epub 2019 Aug 12
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doi: 10.1161/HYPERTENSIONAHA.119.12739.
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<span class="bold">PMID: </span><a href="/pubmed/31401877" target="_blank">31401877</a><a href="/pmc/articles/PMC6756298" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28554307">Hypertensive Disorders in Pregnancy Current Practice Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Turner K,
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Hameed AB</span><br />
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doi: 10.2174/1573402113666170529110024.
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<span class="bold">PMID: </span><a href="/pubmed/28554307" target="_blank">28554307</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%2Feclampsia%205%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (119)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38366809">First-trimester preterm preeclampsia prediction model for prevention with low-dose aspirin.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Pooh RK</span><br />
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<span class="medgenPMjournal">J Obstet Gynaecol Res</span>
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2024 May;50(5):793-799.
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Epub 2024 Feb 17
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<span class="bold">PMID: </span><a href="/pubmed/38366809" target="_blank">38366809</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/37144983">Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Simmons D,
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Immanuel J,
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Hague WM,
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Teede H,
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Nolan CJ,
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Peek MJ,
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Flack JR,
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McLean M,
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Wong V,
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Hibbert E,
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Kautzky-Willer A,
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Harreiter J,
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Backman H,
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Gianatti E,
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Sweeting A,
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Mohan V,
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Enticott J,
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Cheung NW;
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TOBOGM Research Group</span><br />
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<span class="medgenPMjournal">N Engl J Med</span>
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2023 Jun 8;388(23):2132-2144.
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Epub 2023 May 5
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doi: 10.1056/NEJMoa2214956.
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<span class="bold">PMID: </span><a href="/pubmed/37144983" target="_blank">37144983</a></div>
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||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31401877">Randomized Interventional Study on Prediction of Preeclampsia/Eclampsia in Women With Suspected Preeclampsia: INSPIRE.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cerdeira AS,
|
||
O'Sullivan J,
|
||
Ohuma EO,
|
||
Harrington D,
|
||
Szafranski P,
|
||
Black R,
|
||
Mackillop L,
|
||
Impey L,
|
||
Greenwood C,
|
||
James T,
|
||
Smith I,
|
||
Papageorghiou AT,
|
||
Knight M,
|
||
Vatish M</span><br />
|
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<span class="medgenPMjournal">Hypertension</span>
|
||
2019 Oct;74(4):983-990.
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||
Epub 2019 Aug 12
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doi: 10.1161/HYPERTENSIONAHA.119.12739.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31401877" target="_blank">31401877</a><a href="/pmc/articles/PMC6756298" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28554307">Hypertensive Disorders in Pregnancy Current Practice Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Turner K,
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Hameed AB</span><br />
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<span class="medgenPMjournal">Curr Hypertens Rev</span>
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2017;13(2):80-88.
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doi: 10.2174/1573402113666170529110024.
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<span class="bold">PMID: </span><a href="/pubmed/28554307" target="_blank">28554307</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/24503673">Guidelines for the prevention of stroke in women: a statement for healthcare professionals from the American Heart Association/American Stroke Association.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Bushnell C,
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McCullough LD,
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Chireau MV,
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Fedder WN,
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Furie KL,
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Howard VJ,
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Lichtman JH,
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Lisabeth LD,
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Piña IL,
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Reeves MJ,
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Rexrode KM,
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Saposnik G,
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Singh V,
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Towfighi A,
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Vaccarino V,
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Walters MR;
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American Heart Association Stroke Council;
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Council on Cardiovascular and Stroke Nursing;
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Council on Clinical Cardiology;
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Council on Epidemiology and Prevention;
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Council for High Blood Pressure Research</span><br />
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<span class="medgenPMjournal">Stroke</span>
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2014 May;45(5):1545-88.
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<span class="bold">PMID: </span><a href="/pubmed/24503673" target="_blank">24503673</a><a href="/pmc/articles/PMC10152977" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%2Feclampsia%205%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (118)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/33940650">The Impact of Maternal Preeclampsia and Hyperglycemia on the Cardiovascular Health of the Offspring: A Systematic Review and Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hoodbhoy Z,
|
||
Mohammed N,
|
||
Nathani KR,
|
||
Sattar S,
|
||
Chowdhury D,
|
||
Maskatia S,
|
||
Tierney S,
|
||
Hasan B,
|
||
Das JK</span><br />
|
||
<span class="medgenPMjournal">Am J Perinatol</span>
|
||
2023 Mar;40(4):363-374.
|
||
Epub 2021 May 3
|
||
doi: 10.1055/s-0041-1728823.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33940650" target="_blank">33940650</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35098440">Acromegaly and pregnancy: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bandeira DB,
|
||
Olivatti TOF,
|
||
Bolfi F,
|
||
Boguszewski CL,
|
||
Dos Santos Nunes-Nogueira V</span><br />
|
||
<span class="medgenPMjournal">Pituitary</span>
|
||
2022 Jun;25(3):352-362.
|
||
Epub 2022 Jan 30
|
||
doi: 10.1007/s11102-022-01208-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35098440" target="_blank">35098440</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32917311">"Hepatic rupture in preeclampsia and HELLP syndrome: A catastrophic presentation".</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dubey S,
|
||
Rani J</span><br />
|
||
<span class="medgenPMjournal">Taiwan J Obstet Gynecol</span>
|
||
2020 Sep;59(5):643-651.
|
||
doi: 10.1016/j.tjog.2020.07.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32917311" target="_blank">32917311</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32813750">Systematic and meta-analysis of factors associated with preeclampsia and eclampsia in sub-Saharan Africa.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Meazaw MW,
|
||
Chojenta C,
|
||
Muluneh MD,
|
||
Loxton D</span><br />
|
||
<span class="medgenPMjournal">PLoS One</span>
|
||
2020;15(8):e0237600.
|
||
Epub 2020 Aug 19
|
||
doi: 10.1371/journal.pone.0237600.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32813750" target="_blank">32813750</a><a href="/pmc/articles/PMC7437916" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19061708">Cardiovascular sequelae of preeclampsia/eclampsia: a systematic review and meta-analyses.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McDonald SD,
|
||
Malinowski A,
|
||
Zhou Q,
|
||
Yusuf S,
|
||
Devereaux PJ</span><br />
|
||
<span class="medgenPMjournal">Am Heart J</span>
|
||
2008 Nov;156(5):918-30.
|
||
Epub 2008 Oct 2
|
||
doi: 10.1016/j.ahj.2008.06.042.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19061708" target="_blank">19061708</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Preeclampsia%2Feclampsia%205%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (16)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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||
|
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|
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|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
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|
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|
||
|
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C3281288%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C3281288%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (4)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C3281288%5bDISCUI%5d" target="_blank">See all (4)</a></total></li>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=614595" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Preeclampsia/eclampsia%205" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(preeclampsia%2Feclampsia%205)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng133">NICE, 2023</a><div>UK NICE guideline (NG133), Hypertension in pregnancy: diagnosis and management, 2023</div></li></ul></div>
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