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<meta name="keywords" content="C1855579, exercise-induced muscle stiffness, finding, muscle stiffness with exercise, muscle stiffness, exercise-induced, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A type of muscle stiffness that occurs following physical exertion." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=343388
|
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ConceptID=C1855579
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Exercise-induced muscle stiffness</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>343388</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1855579</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
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<td>Muscle stiffness with exercise; Muscle stiffness, exercise-induced</td></tr>
|
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<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0008967">HP:0008967</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">A type of muscle stiffness that occurs following physical exertion. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Exercise-induced muscle stiffness</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/1763488" ref="tree=MeSH" title="MedGen record for Abnormality of the musculoskeletal system">Abnormality of the musculoskeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/867380" ref="tree=MeSH" title="MedGen record for Abnormality of the musculature">Abnormality of the musculature</a></span><ul><li><span class="TLline"><a href="/medgen/868777" ref="tree=MeSH" title="MedGen record for Abnormal muscle physiology">Abnormal muscle physiology</a></span><ul><li><span class="TLline"><a href="/medgen/113151" ref="tree=MeSH" title="MedGen record for Muscle stiffness">Muscle stiffness</a></span><ul><li><span class="matched_ds">Exercise-induced muscle stiffness</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_5342"><div><strong>Glycogen storage disease, type VII</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5342</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017926</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Glycogen storage disease VII is an autosomal recessive metabolic disorder characterized clinically by exercise intolerance, muscle cramping, exertional myopathy, and compensated hemolysis. Myoglobinuria may also occur. The deficiency of the muscle isoform of PFK results in a total and partial loss of muscle and red cell PFK activity, respectively. Raben and Sherman (1995) noted that not all patients with GSD VII seek medical care because in some cases it is a relatively mild disorder.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5342">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_371357"><div><strong>Rippling muscle disease 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>371357</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1832560</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hereditary rippling muscle disease is an autosomal dominant disorder characterized by mechanically triggered contractions of skeletal muscle. In rippling muscle disease, mechanical stimulation leads to electrically silent muscle contractions that spread to neighboring fibers that cause visible ripples to move over the muscle. RMD is usually inherited as an autosomal dominant trait, but autosomal recessive inheritance has also been reported (Kubisch et al., 2005). Genetic Heterogeneity of Rippling Muscle Disease Another locus for RMD, designated RMD1 (600332), maps to chromosome 1q41.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/371357">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_371441"><div><strong>Brody myopathy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>371441</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1832918</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Brody disease (BROD) is an autosomal recessive skeletal muscle disorder characterized by exercise-induced muscle stiffness and cramps primarily affecting the arms, legs, and eyelids, although more generalized muscle involvement may also occur. Symptom onset is most often in the first decade, but many patients present and are diagnosed later in life. Skeletal muscle biopsy typically shows variation in fiber size, increased internal nuclei, and atrophy of type II muscle fibers. Rare patients have been reported to develop malignant hyperthermia after administration of anesthesia, suggesting that patients with the disorder should be tested. The disorder results from defective relaxation of fast-twitch (type II) skeletal muscle fibers due to defects in calcium homeostasis and reuptake in the muscle fiber (summary by Odermatt et al., 2000 and Molenaar et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/371441">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_324987"><div><strong>Rippling muscle disease 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>324987</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1838254</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/324987">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_335112"><div><strong>Glycogen storage disease IXd</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>335112</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1845151</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Phosphorylase kinase (PhK) deficiency causing glycogen storage disease type IX (GSD IX) results from deficiency of the enzyme phosphorylase b kinase, which has a major regulatory role in the breakdown of glycogen. The two types of PhK deficiency are liver PhK deficiency (characterized by early childhood onset of hepatomegaly and growth restriction, and often, but not always, fasting ketosis and hypoglycemia) and muscle PhK deficiency, which is considerably rarer (characterized by any of the following: exercise intolerance, myalgia, muscle cramps, myoglobinuria, and progressive muscle weakness). While symptoms and biochemical abnormalities of liver PhK deficiency were thought to improve with age, it is becoming evident that affected individuals need to be monitored for long-term complications such as liver fibrosis and cirrhosis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/335112">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_344529"><div><strong>Metabolic myopathy due to lactate transporter defect</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>344529</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1855577</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare metabolic myopathy with characteristics of muscle cramping and/or stiffness after exercise (especially during heat exposure), post-exertional rhabdomyolysis and myoglobinuria and elevation of serum creatine kinase. Caused by mutation in the SLC16A1 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/344529">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1824033"><div><strong>Myopathy with myalgia, increased serum creatine kinase, and with or without episodic rhabdomyolysis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1824033</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5774260</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Myopathy with myalgia, increased serum creatine kinase, and with or without episodic rhabdomyolysis-1 (MMCKR1) is an autosomal recessive skeletal muscle disorder characterized by the onset of muscle cramping and stiffness on exertion in infancy or early childhood, although later (even adult) onset has also been reported. The features remit with rest, but some individuals develop mild proximal or distal muscle weakness. Rare affected individuals may demonstrate cardiac involvement, including left ventricular dysfunction or rhythm abnormalities. Laboratory studies show increased baseline serum creatine kinase levels with episodic spikes that may coincide with rhabdomyolysis. EMG shows myopathic changes, and muscle biopsy shows nonspecific myopathic or degenerative features (Lopes Abath Neto et al., 2021; Salzer-Sheelo et al., 2022). Genetic Heterogeneity of Myopathy with Myalgia, Increased Serum Creatine Kinase, and with or without Episodic Rhabdomyolysis MMCKR2 (620971) is caused by mutation in the DTNA gene (601239) on chromosome 18q12.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1824033">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_371441" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Brody myopathy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_335112" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease IXd</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5342" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease, type VII</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_344529" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Metabolic myopathy due to lactate transporter defect</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1824033" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Myopathy with myalgia, increased serum creatine kinase, and with or without episodic rhabdomyolysis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_324987" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Rippling muscle disease 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_371357" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Rippling muscle disease 2</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32040565">Clinical, morphological and genetic characterization of Brody disease: an international study of 40 patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molenaar JP,
|
||
Verhoeven JI,
|
||
Rodenburg RJ,
|
||
Kamsteeg EJ,
|
||
Erasmus CE,
|
||
Vicart S,
|
||
Behin A,
|
||
Bassez G,
|
||
Magot A,
|
||
Péréon Y,
|
||
Brandom BW,
|
||
Guglielmi V,
|
||
Vattemi G,
|
||
Chevessier F,
|
||
Mathieu J,
|
||
Franques J,
|
||
Suetterlin K,
|
||
Hanna MG,
|
||
Guyant-Marechal L,
|
||
Snoeck MM,
|
||
Roberts ME,
|
||
Kuntzer T,
|
||
Fernandez-Torron R,
|
||
Martínez-Arroyo A,
|
||
Seeger J,
|
||
Kusters B,
|
||
Treves S,
|
||
van Engelen BG,
|
||
Eymard B,
|
||
Voermans NC,
|
||
Sternberg D</span><br />
|
||
<span class="medgenPMjournal">Brain</span>
|
||
2020 Feb 1;143(2):452-466.
|
||
doi: 10.1093/brain/awz410.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32040565" target="_blank">32040565</a><a href="/pmc/articles/PMC7009512" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Exercise-induced%20muscle%20stiffness%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32040565">Clinical, morphological and genetic characterization of Brody disease: an international study of 40 patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molenaar JP,
|
||
Verhoeven JI,
|
||
Rodenburg RJ,
|
||
Kamsteeg EJ,
|
||
Erasmus CE,
|
||
Vicart S,
|
||
Behin A,
|
||
Bassez G,
|
||
Magot A,
|
||
Péréon Y,
|
||
Brandom BW,
|
||
Guglielmi V,
|
||
Vattemi G,
|
||
Chevessier F,
|
||
Mathieu J,
|
||
Franques J,
|
||
Suetterlin K,
|
||
Hanna MG,
|
||
Guyant-Marechal L,
|
||
Snoeck MM,
|
||
Roberts ME,
|
||
Kuntzer T,
|
||
Fernandez-Torron R,
|
||
Martínez-Arroyo A,
|
||
Seeger J,
|
||
Kusters B,
|
||
Treves S,
|
||
van Engelen BG,
|
||
Eymard B,
|
||
Voermans NC,
|
||
Sternberg D</span><br />
|
||
<span class="medgenPMjournal">Brain</span>
|
||
2020 Feb 1;143(2):452-466.
|
||
doi: 10.1093/brain/awz410.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32040565" target="_blank">32040565</a><a href="/pmc/articles/PMC7009512" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20445432">A case of paramyotonia congenita without periodic paralysis: electrophysiological and molecular genetic studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Park JH,
|
||
Lee YW,
|
||
Park SA,
|
||
Lee TK,
|
||
Rho HJ,
|
||
Sung KB</span><br />
|
||
<span class="medgenPMjournal">Neurologist</span>
|
||
2010 May;16(3):203-5.
|
||
doi: 10.1097/NRL.0b013e3181a3cb6c.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20445432" target="_blank">20445432</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10424227">Occult presentation of myotonia congenita in a 15-year-old athlete.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weinberg J,
|
||
Curl LA,
|
||
Kuncl RW,
|
||
McFarland EG</span><br />
|
||
<span class="medgenPMjournal">Am J Sports Med</span>
|
||
1999 Jul-Aug;27(4):529-31.
|
||
doi: 10.1177/03635465990270042101.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10424227" target="_blank">10424227</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Exercise-induced%20muscle%20stiffness%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/20445432">A case of paramyotonia congenita without periodic paralysis: electrophysiological and molecular genetic studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Park JH,
|
||
Lee YW,
|
||
Park SA,
|
||
Lee TK,
|
||
Rho HJ,
|
||
Sung KB</span><br />
|
||
<span class="medgenPMjournal">Neurologist</span>
|
||
2010 May;16(3):203-5.
|
||
doi: 10.1097/NRL.0b013e3181a3cb6c.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20445432" target="_blank">20445432</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Exercise-induced%20muscle%20stiffness%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/10424227">Occult presentation of myotonia congenita in a 15-year-old athlete.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weinberg J,
|
||
Curl LA,
|
||
Kuncl RW,
|
||
McFarland EG</span><br />
|
||
<span class="medgenPMjournal">Am J Sports Med</span>
|
||
1999 Jul-Aug;27(4):529-31.
|
||
doi: 10.1177/03635465990270042101.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10424227" target="_blank">10424227</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Exercise-induced%20muscle%20stiffness%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32040565">Clinical, morphological and genetic characterization of Brody disease: an international study of 40 patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Molenaar JP,
|
||
Verhoeven JI,
|
||
Rodenburg RJ,
|
||
Kamsteeg EJ,
|
||
Erasmus CE,
|
||
Vicart S,
|
||
Behin A,
|
||
Bassez G,
|
||
Magot A,
|
||
Péréon Y,
|
||
Brandom BW,
|
||
Guglielmi V,
|
||
Vattemi G,
|
||
Chevessier F,
|
||
Mathieu J,
|
||
Franques J,
|
||
Suetterlin K,
|
||
Hanna MG,
|
||
Guyant-Marechal L,
|
||
Snoeck MM,
|
||
Roberts ME,
|
||
Kuntzer T,
|
||
Fernandez-Torron R,
|
||
Martínez-Arroyo A,
|
||
Seeger J,
|
||
Kusters B,
|
||
Treves S,
|
||
van Engelen BG,
|
||
Eymard B,
|
||
Voermans NC,
|
||
Sternberg D</span><br />
|
||
<span class="medgenPMjournal">Brain</span>
|
||
2020 Feb 1;143(2):452-466.
|
||
doi: 10.1093/brain/awz410.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32040565" target="_blank">32040565</a><a href="/pmc/articles/PMC7009512" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Exercise-induced%20muscle%20stiffness%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
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|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
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|
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|
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Exercise-induced%20muscle%20stiffness" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<a href="/pubmed/clinical?term=Exercise-induced%20muscle%20stiffness" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a href="/pubmed?term=Exercise-induced%20muscle%20stiffness%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67ce915884f3725e59275046">Exercise-induced muscle stiffness</a>
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<div class="ralinkpop offscreen_noflow">C1855580[trait identifier] AND "Centre for Mendelian Genomics, University Medical Centre Ljubljana"[submitter]<div class="brieflinkpopdesc">Search</div></div>
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