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<meta name="keywords" content="C0345905, cholangiocarcinoma of intrahepatic biliary tract, cholangiocarcinoma, intrahepatic, cholangiocarcinoma, intrahepatic, malignant, cholangiocarcinomas, intrahepatic, icc, ihch, intrahepatic bile duct cancer (cholangiocarcinoma), intrahepatic bile duct carcinoma, intrahepatic carcinoma of bile duct, intrahepatic carcinoma of the bile duct, intrahepatic cholangiocarcinoma, intrahepatic cholangiocarcinoma (bile duct cancer), intrahepatic cholangiocarcinomas, intrahepatic cholangiocellular carcinoma, neoplastic process, peripheral cholangiocarcinoma, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=87521
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ConceptID=C0345905
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Intrahepatic cholangiocarcinoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>87521</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0345905</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Cholangiocarcinoma, Intrahepatic; Cholangiocarcinomas, Intrahepatic; Intrahepatic Cholangiocarcinoma; Intrahepatic Cholangiocarcinomas</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Intrahepatic bile duct carcinoma (109842005); Cholangiocarcinoma of intrahepatic biliary tract (1260050006); Intrahepatic cholangiocarcinoma (1260050006)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0003210" target="_blank">MONDO:0003210</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Intrahepatic cholangiocarcinoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/277963" ref="tree=MeSH" title="MedGen record for Epithelial neoplasm">Epithelial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2867" ref="tree=MeSH" title="MedGen record for Carcinoma">Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/57467" ref="tree=MeSH" title="MedGen record for Gastrointestinal carcinoma">Gastrointestinal carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/78921" ref="tree=MeSH" title="MedGen record for Carcinoma of liver and intrahepatic biliary tract">Carcinoma of liver and intrahepatic biliary tract</a></span><ul><li><span class="matched_ds">Intrahepatic cholangiocarcinoma</span><ul><li><span class="TLline"><a href="/medgen/273143" ref="tree=MeSH" title="MedGen record for Cholangiolocellular carcinoma">Cholangiolocellular carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/317517" ref="tree=MeSH" title="MedGen record for Clear Cell Intrahepatic Cholangiocarcinoma">Clear Cell Intrahepatic Cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/474769" ref="tree=MeSH" title="MedGen record for Intrahepatic Bile Duct Intraductal Papillary Neoplasm with an Associated Invasive Carcinoma">Intrahepatic Bile Duct Intraductal Papillary Neoplasm with an Associated Invasive Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1628168" ref="tree=MeSH" title="MedGen record for Intrahepatic Cholangiocarcinoma by AJCC v7 Stage">Intrahepatic Cholangiocarcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/453850" ref="tree=MeSH" title="MedGen record for Stage 0 Intrahepatic Cholangiocarcinoma AJCC v7">Stage 0 Intrahepatic Cholangiocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/453851" ref="tree=MeSH" title="MedGen record for Stage I Intrahepatic Cholangiocarcinoma AJCC v7">Stage I Intrahepatic Cholangiocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/453852" ref="tree=MeSH" title="MedGen record for Stage II Intrahepatic Cholangiocarcinoma AJCC v7">Stage II Intrahepatic Cholangiocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/453853" ref="tree=MeSH" title="MedGen record for Stage III Intrahepatic Cholangiocarcinoma AJCC v7">Stage III Intrahepatic Cholangiocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/453854" ref="tree=MeSH" title="MedGen record for Stage IVA Intrahepatic Cholangiocarcinoma AJCC v7">Stage IVA Intrahepatic Cholangiocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/453855" ref="tree=MeSH" title="MedGen record for Stage IVB Intrahepatic Cholangiocarcinoma AJCC v7">Stage IVB Intrahepatic Cholangiocarcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1616489" ref="tree=MeSH" title="MedGen record for Intrahepatic Cholangiocarcinoma by AJCC v8 Stage">Intrahepatic Cholangiocarcinoma by AJCC v8 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1619486" ref="tree=MeSH" title="MedGen record for Stage 0 Intrahepatic Cholangiocarcinoma AJCC v8">Stage 0 Intrahepatic Cholangiocarcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1614984" ref="tree=MeSH" title="MedGen record for Stage I Intrahepatic Cholangiocarcinoma AJCC v8">Stage I Intrahepatic Cholangiocarcinoma AJCC v8</a></span><ul><li><span class="TLline"><a href="/medgen/1613689" ref="tree=MeSH" title="MedGen record for Stage IA Intrahepatic Cholangiocarcinoma AJCC v8">Stage IA Intrahepatic Cholangiocarcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1618618" ref="tree=MeSH" title="MedGen record for Stage IB Intrahepatic Cholangiocarcinoma AJCC v8">Stage IB Intrahepatic Cholangiocarcinoma AJCC v8</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1623564" ref="tree=MeSH" title="MedGen record for Stage II Intrahepatic Cholangiocarcinoma AJCC v8">Stage II Intrahepatic Cholangiocarcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1616317" ref="tree=MeSH" title="MedGen record for Stage III Intrahepatic Cholangiocarcinoma AJCC v8">Stage III Intrahepatic Cholangiocarcinoma AJCC v8</a></span><ul><li><span class="TLline"><a href="/medgen/1627125" ref="tree=MeSH" title="MedGen record for Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8">Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1622553" ref="tree=MeSH" title="MedGen record for Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8">Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1612157" ref="tree=MeSH" title="MedGen record for Stage IV Intrahepatic Cholangiocarcinoma AJCC v8">Stage IV Intrahepatic Cholangiocarcinoma AJCC v8</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1762846" ref="tree=MeSH" title="MedGen record for Large Duct Intrahepatic Cholangiocarcinoma">Large Duct Intrahepatic Cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1777207" ref="tree=MeSH" title="MedGen record for Metastatic Intrahepatic Cholangiocarcinoma">Metastatic Intrahepatic Cholangiocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1778739" ref="tree=MeSH" title="MedGen record for Advanced Intrahepatic Cholangiocarcinoma">Advanced Intrahepatic Cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1776433" ref="tree=MeSH" title="MedGen record for Locally Advanced Intrahepatic Cholangiocarcinoma">Locally Advanced Intrahepatic Cholangiocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/270842" ref="tree=MeSH" title="MedGen record for Mucinous intrahepatic cholangiocarcinoma">Mucinous intrahepatic cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/923759" ref="tree=MeSH" title="MedGen record for Recurrent Intrahepatic Cholangiocarcinoma">Recurrent Intrahepatic Cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1775959" ref="tree=MeSH" title="MedGen record for Refractory Intrahepatic Cholangiocarcinoma">Refractory Intrahepatic Cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1666496" ref="tree=MeSH" title="MedGen record for Resectable Intrahepatic Cholangiocarcinoma">Resectable Intrahepatic Cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/275403" ref="tree=MeSH" title="MedGen record for Sarcomatous intrahepatic cholangiocarcinoma">Sarcomatous intrahepatic cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/276815" ref="tree=MeSH" title="MedGen record for Signet ring cell intrahepatic cholangiocarcinoma">Signet ring cell intrahepatic cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/474681" ref="tree=MeSH" title="MedGen record for Small Duct Intrahepatic Cholangiocarcinoma">Small Duct Intrahepatic Cholangiocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1664280" ref="tree=MeSH" title="MedGen record for Unresectable Intrahepatic Cholangiocarcinoma">Unresectable Intrahepatic Cholangiocarcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36260350">Advances in the treatment of intrahepatic cholangiocarcinoma: An overview of the current and future therapeutic landscape for clinicians.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moris D,
|
||
Palta M,
|
||
Kim C,
|
||
Allen PJ,
|
||
Morse MA,
|
||
Lidsky ME</span><br />
|
||
<span class="medgenPMjournal">CA Cancer J Clin</span>
|
||
2023 Mar;73(2):198-222.
|
||
Epub 2022 Oct 19
|
||
doi: 10.3322/caac.21759.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36260350" target="_blank">36260350</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24681130">Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bridgewater J,
|
||
Galle PR,
|
||
Khan SA,
|
||
Llovet JM,
|
||
Park JW,
|
||
Patel T,
|
||
Pawlik TM,
|
||
Gores GJ</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2014 Jun;60(6):1268-89.
|
||
Epub 2014 Mar 27
|
||
doi: 10.1016/j.jhep.2014.01.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24681130" target="_blank">24681130</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24140396">Pathogenesis, diagnosis, and management of cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ilyas SI,
|
||
Gores GJ</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2013 Dec;145(6):1215-29.
|
||
Epub 2013 Oct 15
|
||
doi: 10.1053/j.gastro.2013.10.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24140396" target="_blank">24140396</a><a href="/pmc/articles/PMC3862291" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22intrahepatic%20cholangiocarcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (247)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/btc.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Biliary Tract Cancers, 2024</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37084797">EASL-ILCA Clinical Practice Guidelines on the management of intrahepatic cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">European Association for the Study of the Liver</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2023 Jul;79(1):181-208.
|
||
Epub 2023 Apr 20
|
||
doi: 10.1016/j.jhep.2023.03.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37084797" target="_blank">37084797</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33516341">Biliary tract cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Valle JW,
|
||
Kelley RK,
|
||
Nervi B,
|
||
Oh DY,
|
||
Zhu AX</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2021 Jan 30;397(10272):428-444.
|
||
doi: 10.1016/S0140-6736(21)00153-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33516341" target="_blank">33516341</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32059499">Asbestos and Intrahepatic Cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brandi G,
|
||
Tavolari S</span><br />
|
||
<span class="medgenPMjournal">Cells</span>
|
||
2020 Feb 12;9(2)
|
||
doi: 10.3390/cells9020421.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32059499" target="_blank">32059499</a><a href="/pmc/articles/PMC7072580" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31472907">Intrahepatic Cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">El-Diwany R,
|
||
Pawlik TM,
|
||
Ejaz A</span><br />
|
||
<span class="medgenPMjournal">Surg Oncol Clin N Am</span>
|
||
2019 Oct;28(4):587-599.
|
||
doi: 10.1016/j.soc.2019.06.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31472907" target="_blank">31472907</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28975830">Epidemiology of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Massarweh NN,
|
||
El-Serag HB</span><br />
|
||
<span class="medgenPMjournal">Cancer Control</span>
|
||
2017 Jul-Sep;24(3):1073274817729245.
|
||
doi: 10.1177/1073274817729245.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28975830" target="_blank">28975830</a><a href="/pmc/articles/PMC5937247" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Intrahepatic%20cholangiocarcinoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1954)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39448128">Cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Harrison JM,
|
||
Visser BC</span><br />
|
||
<span class="medgenPMjournal">Surg Clin North Am</span>
|
||
2024 Dec;104(6):1281-1293.
|
||
Epub 2024 May 10
|
||
doi: 10.1016/j.suc.2024.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39448128" target="_blank">39448128</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33516341">Biliary tract cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Valle JW,
|
||
Kelley RK,
|
||
Nervi B,
|
||
Oh DY,
|
||
Zhu AX</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2021 Jan 30;397(10272):428-444.
|
||
doi: 10.1016/S0140-6736(21)00153-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33516341" target="_blank">33516341</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32402299">Primary Liver Cancers: Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mejia JC,
|
||
Pasko J</span><br />
|
||
<span class="medgenPMjournal">Surg Clin North Am</span>
|
||
2020 Jun;100(3):535-549.
|
||
Epub 2020 Apr 16
|
||
doi: 10.1016/j.suc.2020.02.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32402299" target="_blank">32402299</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24681130">Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bridgewater J,
|
||
Galle PR,
|
||
Khan SA,
|
||
Llovet JM,
|
||
Park JW,
|
||
Patel T,
|
||
Pawlik TM,
|
||
Gores GJ</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2014 Jun;60(6):1268-89.
|
||
Epub 2014 Mar 27
|
||
doi: 10.1016/j.jhep.2014.01.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24681130" target="_blank">24681130</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24560108">Intrahepatic cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brown KM,
|
||
Parmar AD,
|
||
Geller DA</span><br />
|
||
<span class="medgenPMjournal">Surg Oncol Clin N Am</span>
|
||
2014 Apr;23(2):231-46.
|
||
doi: 10.1016/j.soc.2013.10.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24560108" target="_blank">24560108</a><a href="/pmc/articles/PMC4007210" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Intrahepatic%20cholangiocarcinoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1480)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36652354">Futibatinib for FGFR2-Rearranged Intrahepatic Cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Goyal L,
|
||
Meric-Bernstam F,
|
||
Hollebecque A,
|
||
Valle JW,
|
||
Morizane C,
|
||
Karasic TB,
|
||
Abrams TA,
|
||
Furuse J,
|
||
Kelley RK,
|
||
Cassier PA,
|
||
Klümpen HJ,
|
||
Chang HM,
|
||
Chen LT,
|
||
Tabernero J,
|
||
Oh DY,
|
||
Mahipal A,
|
||
Moehler M,
|
||
Mitchell EP,
|
||
Komatsu Y,
|
||
Masuda K,
|
||
Ahn D,
|
||
Epstein RS,
|
||
Halim AB,
|
||
Fu Y,
|
||
Salimi T,
|
||
Wacheck V,
|
||
He Y,
|
||
Liu M,
|
||
Benhadji KA,
|
||
Bridgewater JA;
|
||
FOENIX-CCA2 Study Investigators</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2023 Jan 19;388(3):228-239.
|
||
doi: 10.1056/NEJMoa2206834.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36652354" target="_blank">36652354</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36260350">Advances in the treatment of intrahepatic cholangiocarcinoma: An overview of the current and future therapeutic landscape for clinicians.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moris D,
|
||
Palta M,
|
||
Kim C,
|
||
Allen PJ,
|
||
Morse MA,
|
||
Lidsky ME</span><br />
|
||
<span class="medgenPMjournal">CA Cancer J Clin</span>
|
||
2023 Mar;73(2):198-222.
|
||
Epub 2022 Oct 19
|
||
doi: 10.3322/caac.21759.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36260350" target="_blank">36260350</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32402299">Primary Liver Cancers: Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mejia JC,
|
||
Pasko J</span><br />
|
||
<span class="medgenPMjournal">Surg Clin North Am</span>
|
||
2020 Jun;100(3):535-549.
|
||
Epub 2020 Apr 16
|
||
doi: 10.1016/j.suc.2020.02.013.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32402299" target="_blank">32402299</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31954497">Systemic therapies for intrahepatic cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kelley RK,
|
||
Bridgewater J,
|
||
Gores GJ,
|
||
Zhu AX</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2020 Feb;72(2):353-363.
|
||
doi: 10.1016/j.jhep.2019.10.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31954497" target="_blank">31954497</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30843343">Surgery for cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cillo U,
|
||
Fondevila C,
|
||
Donadon M,
|
||
Gringeri E,
|
||
Mocchegiani F,
|
||
Schlitt HJ,
|
||
Ijzermans JNM,
|
||
Vivarelli M,
|
||
Zieniewicz K,
|
||
Olde Damink SWM,
|
||
Groot Koerkamp B</span><br />
|
||
<span class="medgenPMjournal">Liver Int</span>
|
||
2019 May;39 Suppl 1(Suppl Suppl 1):143-155.
|
||
doi: 10.1111/liv.14089.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30843343" target="_blank">30843343</a><a href="/pmc/articles/PMC6563077" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Intrahepatic%20cholangiocarcinoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (863)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36208844">Global burden of primary liver cancer in 2020 and predictions to 2040.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rumgay H,
|
||
Arnold M,
|
||
Ferlay J,
|
||
Lesi O,
|
||
Cabasag CJ,
|
||
Vignat J,
|
||
Laversanne M,
|
||
McGlynn KA,
|
||
Soerjomataram I</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2022 Dec;77(6):1598-1606.
|
||
Epub 2022 Oct 5
|
||
doi: 10.1016/j.jhep.2022.08.021.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36208844" target="_blank">36208844</a><a href="/pmc/articles/PMC9670241" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31954497">Systemic therapies for intrahepatic cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kelley RK,
|
||
Bridgewater J,
|
||
Gores GJ,
|
||
Zhu AX</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
2020 Feb;72(2):353-363.
|
||
doi: 10.1016/j.jhep.2019.10.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31954497" target="_blank">31954497</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29735023">Liver Transplant for Cholangiocarcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zamora-Valdes D,
|
||
Heimbach JK</span><br />
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<div class="nl"><a target="_blank" href="/pubmed/24140396">Pathogenesis, diagnosis, and management of cholangiocarcinoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ilyas SI,
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<span class="medgenPMjournal">Gastroenterology</span>
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2013 Dec;145(6):1215-29.
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<div class="nl"><a target="_blank" href="/pubmed/20637950">Intrahepatic cholangiocarcinoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Poultsides GA,
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Choti MA,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Intrahepatic%20cholangiocarcinoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2212)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/34793865">Distribution and density of tertiary lymphoid structures predict clinical outcome in intrahepatic cholangiocarcinoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ding GY,
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Ma JQ,
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Yun JP,
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Chen X,
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Ling Y,
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Zhang S,
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Shi JY,
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Chang YQ,
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Ji Y,
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Wang XY,
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Tan WM,
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Yuan KF,
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Yan B,
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Zhang XM,
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Liang F,
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Zhou J,
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<span class="bold">PMID: </span><a href="/pubmed/34793865" target="_blank">34793865</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Brandi G,
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Tavolari S</span><br />
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<span class="medgenPMjournal">Cells</span>
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2020 Feb 12;9(2)
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<div class="nl"><a target="_blank" href="/pubmed/31472907">Intrahepatic Cholangiocarcinoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">El-Diwany R,
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Pawlik TM,
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2019 Oct;28(4):587-599.
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<span class="bold">PMID: </span><a href="/pubmed/31472907" target="_blank">31472907</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31130341">Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Xue R,
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Chen L,
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Zhang C,
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Fujita M,
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Li R,
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Yan SM,
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Ong CK,
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Liao X,
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Gao Q,
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Sasagawa S,
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Li Y,
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Wang J,
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Guo H,
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Huang QT,
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Zhong Q,
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Tan J,
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Qi L,
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Gong W,
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2019 Jun 10;35(6):932-947.e8.
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<span class="bold">PMID: </span><a href="/pubmed/31130341" target="_blank">31130341</a><a href="/pmc/articles/PMC8317046" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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|
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<div class="nl"><a target="_blank" href="/pubmed/26615163">Intrahepatic Cholangiocarcinoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Padia SA</span><br />
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2015 Dec;18(4):227-35.
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Epub 2015 Jul 15
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<span class="bold">PMID: </span><a href="/pubmed/26615163" target="_blank">26615163</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Intrahepatic%20cholangiocarcinoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1418)</a></div></div>
|
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|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38071187">Value of lymph node dissection in intrahepatic cholangiocarcinoma: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yeow M,
|
||
Fong KY,
|
||
Zhao JJ,
|
||
Tan AYH,
|
||
Koh YX,
|
||
Kam JH,
|
||
Goh BKP,
|
||
Pawlik TM,
|
||
Kabir T</span><br />
|
||
<span class="medgenPMjournal">HPB (Oxford)</span>
|
||
2024 Feb;26(2):161-170.
|
||
Epub 2023 Nov 20
|
||
doi: 10.1016/j.hpb.2023.11.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38071187" target="_blank">38071187</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35574621">Adjuvant Transarterial Chemoembolization for Patients with Intrahepatic Cholangiocarcinoma after Surgical Resection: A Systematic Review and Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang L,
|
||
Wen X,
|
||
Zhuang L,
|
||
Fang K,
|
||
Shen J</span><br />
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<span class="medgenPMjournal">J Gastrointestin Liver Dis</span>
|
||
2022 Jun 12;31(2):215-222.
|
||
doi: 10.15403/jgld-4207.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35574621" target="_blank">35574621</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34688956">External Beam Radiation Therapy for Primary Liver Cancers: An ASTRO Clinical Practice Guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Apisarnthanarax S,
|
||
Barry A,
|
||
Cao M,
|
||
Czito B,
|
||
DeMatteo R,
|
||
Drinane M,
|
||
Hallemeier CL,
|
||
Koay EJ,
|
||
Lasley F,
|
||
Meyer J,
|
||
Owen D,
|
||
Pursley J,
|
||
Schaub SK,
|
||
Smith G,
|
||
Venepalli NK,
|
||
Zibari G,
|
||
Cardenes H</span><br />
|
||
<span class="medgenPMjournal">Pract Radiat Oncol</span>
|
||
2022 Jan-Feb;12(1):28-51.
|
||
Epub 2021 Oct 21
|
||
doi: 10.1016/j.prro.2021.09.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34688956" target="_blank">34688956</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32622478">Conversion therapy for intrahepatic cholangiocarcinoma and tumor downsizing to increase resection rates: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fruscione M,
|
||
Pickens RC,
|
||
Baker EH,
|
||
Martinie JB,
|
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Iannitti DA,
|
||
Hwang JJ,
|
||
Vrochides D</span><br />
|
||
<span class="medgenPMjournal">Curr Probl Cancer</span>
|
||
2021 Feb;45(1):100614.
|
||
Epub 2020 Jun 20
|
||
doi: 10.1016/j.currproblcancer.2020.100614.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32622478" target="_blank">32622478</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25555821">Type 2 diabetes and cancer: umbrella review of meta-analyses of observational studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tsilidis KK,
|
||
Kasimis JC,
|
||
Lopez DS,
|
||
Ntzani EE,
|
||
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|
||
2015 Jan 2;350:g7607.
|
||
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|
||
<span class="bold">PMID: </span><a href="/pubmed/25555821" target="_blank">25555821</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Intrahepatic%20cholangiocarcinoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (78)</a></div></div>
|
||
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|
||
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|
||
<div class="supplemental col three_col last">
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||
<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Intrahepatic%20cholangiocarcinoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22intrahepatic%20cholangiocarcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Intrahepatic%20cholangiocarcinoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/btc.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Biliary Tract Cancers, 2024</div></li></ul></div>
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<a href="/pubmed/clinical?term=Intrahepatic%20cholangiocarcinoma" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a href="/pubmed?term=Intrahepatic%20cholangiocarcinoma%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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