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<meta name="keywords" content="C0149978, adenocarcinoma - rectum, adenocarcinoma of rectum, adenocarcinoma of the rectum, neoplastic process, read, rectal adenocarcinoma, rectum adenocarcinoma, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="An adenocarcinoma arising from the rectum. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, rectal adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=56214
|
||
ConceptID=C0149978
|
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Rectum adenocarcinoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>56214</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0149978</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Rectal Adenocarcinoma</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Adenocarcinoma of rectum (254582000)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0002169" target="_blank">MONDO:0002169</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">An adenocarcinoma arising from the rectum. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, rectal adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
|
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Rectum adenocarcinoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/277963" ref="tree=MeSH" title="MedGen record for Epithelial neoplasm">Epithelial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2867" ref="tree=MeSH" title="MedGen record for Carcinoma">Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/122" ref="tree=MeSH" title="MedGen record for Adenocarcinoma">Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/230816" ref="tree=MeSH" title="MedGen record for Adenocarcinoma of the large intestine">Adenocarcinoma of the large intestine</a></span><ul><li><span class="matched_ds">Rectum adenocarcinoma</span><ul><li><span class="TLline"><a href="/medgen/272683" ref="tree=MeSH" title="MedGen record for Grade 1 Rectal Adenocarcinoma">Grade 1 Rectal Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/232567" ref="tree=MeSH" title="MedGen record for Grade 2 Rectal Adenocarcinoma">Grade 2 Rectal Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234320" ref="tree=MeSH" title="MedGen record for Grade 3 Rectal Adenocarcinoma">Grade 3 Rectal Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1695687" ref="tree=MeSH" title="MedGen record for Metastatic Rectal Adenocarcinoma">Metastatic Rectal Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1784958" ref="tree=MeSH" title="MedGen record for Advanced Rectal Adenocarcinoma">Advanced Rectal Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1741687" ref="tree=MeSH" title="MedGen record for Locally Advanced Rectal Adenocarcinoma">Locally Advanced Rectal Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1699799" ref="tree=MeSH" title="MedGen record for Locally Advanced Unresectable Rectal Adenocarcinoma">Locally Advanced Unresectable Rectal Adenocarcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/474447" ref="tree=MeSH" title="MedGen record for Rectal Cribriform Comedo-Type Adenocarcinoma">Rectal Cribriform Comedo-Type Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/364314" ref="tree=MeSH" title="MedGen record for Rectal medullary carcinoma">Rectal medullary carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/474450" ref="tree=MeSH" title="MedGen record for Rectal Micropapillary Adenocarcinoma">Rectal Micropapillary Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/474444" ref="tree=MeSH" title="MedGen record for Rectal Serrated Adenocarcinoma">Rectal Serrated Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/124641" ref="tree=MeSH" title="MedGen record for Rectal signet ring cell adenocarcinoma">Rectal signet ring cell adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83537" ref="tree=MeSH" title="MedGen record for Rectum mucinous adenocarcinoma">Rectum mucinous adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1691586" ref="tree=MeSH" title="MedGen record for Recurrent Rectal Adenocarcinoma">Recurrent Rectal Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1691064" ref="tree=MeSH" title="MedGen record for Refractory Rectal Adenocarcinoma">Refractory Rectal Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1707346" ref="tree=MeSH" title="MedGen record for Unresectable Rectal Adenocarcinoma">Unresectable Rectal Adenocarcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38007705">APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao S,
|
||
Li Y,
|
||
Xu J,
|
||
Shen L</span><br />
|
||
<span class="medgenPMjournal">Neurol Res</span>
|
||
2024 Mar;46(3):227-242.
|
||
Epub 2024 Jan 22
|
||
doi: 10.1080/01616412.2023.2287340.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38007705" target="_blank">38007705</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30871581">Tumor budding for predicting prognosis of resected rectum cancer after neoadjuvant treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Demir A,
|
||
Alan O,
|
||
Oruc E</span><br />
|
||
<span class="medgenPMjournal">World J Surg Oncol</span>
|
||
2019 Mar 14;17(1):50.
|
||
doi: 10.1186/s12957-019-1588-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30871581" target="_blank">30871581</a><a href="/pmc/articles/PMC6419499" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24764671">Role of triamcinolone in radiation enteritis management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cetin E,
|
||
Ozturk AS,
|
||
Orhun H,
|
||
Ulger S</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2014 Apr 21;20(15):4341-4.
|
||
doi: 10.3748/wjg.v20.i15.4341.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24764671" target="_blank">24764671</a><a href="/pmc/articles/PMC3989969" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22rectum%20adenocarcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (6)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38938617">Prognostic and therapeutic insights into colorectal carcinoma through immunogenic cell death gene profiling.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yu J,
|
||
Gong Y,
|
||
Xu Z,
|
||
Chen L,
|
||
Li S,
|
||
Cui Y</span><br />
|
||
<span class="medgenPMjournal">PeerJ</span>
|
||
2024;12:e17629.
|
||
Epub 2024 Jun 24
|
||
doi: 10.7717/peerj.17629.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38938617" target="_blank">38938617</a><a href="/pmc/articles/PMC11210462" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38012642">Research on radiotherapy related genes and prognostic target identification of rectal cancer based on multi-omics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu Y,
|
||
Yang Y,
|
||
Ni F,
|
||
Tai G,
|
||
Yu C,
|
||
Jiang X,
|
||
Wang D</span><br />
|
||
<span class="medgenPMjournal">J Transl Med</span>
|
||
2023 Nov 27;21(1):856.
|
||
doi: 10.1186/s12967-023-04753-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38012642" target="_blank">38012642</a><a href="/pmc/articles/PMC10680259" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34531868">Pan-Cancer Analysis of PARP1 Alterations as Biomarkers in the Prediction of Immunotherapeutic Effects and the Association of Its Expression Levels and Immunotherapy Signatures.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang X,
|
||
Wang Y,
|
||
A G,
|
||
Qu C,
|
||
Chen J</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2021;12:721030.
|
||
Epub 2021 Aug 31
|
||
doi: 10.3389/fimmu.2021.721030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34531868" target="_blank">34531868</a><a href="/pmc/articles/PMC8438309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34373442">Identification of m6A-Related Biomarkers Associated with Prognosis of Colorectal Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang Z,
|
||
Zhang X</span><br />
|
||
<span class="medgenPMjournal">Med Sci Monit</span>
|
||
2021 Aug 10;27:e932370.
|
||
doi: 10.12659/MSM.932370.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34373442" target="_blank">34373442</a><a href="/pmc/articles/PMC8364289" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32482534">"Decision for adjuvant treatment in stage II colon cancer based on circulating tumor DNA:The CIRCULATE-PRODIGE 70 trial".</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Taïeb J,
|
||
Benhaim L,
|
||
Laurent Puig P,
|
||
Le Malicot K,
|
||
Emile JF,
|
||
Geillon F,
|
||
Tougeron D,
|
||
Manfredi S,
|
||
Chauvenet M,
|
||
Taly V,
|
||
Lepage C,
|
||
André T</span><br />
|
||
<span class="medgenPMjournal">Dig Liver Dis</span>
|
||
2020 Jul;52(7):730-733.
|
||
Epub 2020 May 29
|
||
doi: 10.1016/j.dld.2020.04.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32482534" target="_blank">32482534</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Rectum%20adenocarcinoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (45)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39167075">Tumor cell-intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miao N,
|
||
Cao D,
|
||
Jin J,
|
||
Ma G,
|
||
Yu H,
|
||
Qu J,
|
||
Li G,
|
||
Gao C,
|
||
Dong D,
|
||
Xia F,
|
||
Li W</span><br />
|
||
<span class="medgenPMjournal">J Exp Med</span>
|
||
2024 Oct 7;221(10)
|
||
Epub 2024 Aug 21
|
||
doi: 10.1084/jem.20231486.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39167075" target="_blank">39167075</a><a href="/pmc/articles/PMC11338319" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36879254">Identification of hub genes and potential molecular mechanisms related to radiotherapy sensitivity in rectal cancer based on multiple datasets.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao P,
|
||
Zhen H,
|
||
Zhao H,
|
||
Huang Y,
|
||
Cao B</span><br />
|
||
<span class="medgenPMjournal">J Transl Med</span>
|
||
2023 Mar 6;21(1):176.
|
||
doi: 10.1186/s12967-023-04029-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36879254" target="_blank">36879254</a><a href="/pmc/articles/PMC9987056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36773567">MARCO is a potential prognostic and immunotherapy biomarker.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dong Q,
|
||
Zhang S,
|
||
Zhang H,
|
||
Sun J,
|
||
Lu J,
|
||
Wang G,
|
||
Wang X</span><br />
|
||
<span class="medgenPMjournal">Int Immunopharmacol</span>
|
||
2023 Mar;116:109783.
|
||
Epub 2023 Feb 9
|
||
doi: 10.1016/j.intimp.2023.109783.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36773567" target="_blank">36773567</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34531868">Pan-Cancer Analysis of PARP1 Alterations as Biomarkers in the Prediction of Immunotherapeutic Effects and the Association of Its Expression Levels and Immunotherapy Signatures.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang X,
|
||
Wang Y,
|
||
A G,
|
||
Qu C,
|
||
Chen J</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2021;12:721030.
|
||
Epub 2021 Aug 31
|
||
doi: 10.3389/fimmu.2021.721030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34531868" target="_blank">34531868</a><a href="/pmc/articles/PMC8438309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32903444">Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin A,
|
||
Zhang J,
|
||
Luo P</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2020;11:2039.
|
||
Epub 2020 Aug 12
|
||
doi: 10.3389/fimmu.2020.02039.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32903444" target="_blank">32903444</a><a href="/pmc/articles/PMC7435056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Rectum%20adenocarcinoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (50)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38012642">Research on radiotherapy related genes and prognostic target identification of rectal cancer based on multi-omics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu Y,
|
||
Yang Y,
|
||
Ni F,
|
||
Tai G,
|
||
Yu C,
|
||
Jiang X,
|
||
Wang D</span><br />
|
||
<span class="medgenPMjournal">J Transl Med</span>
|
||
2023 Nov 27;21(1):856.
|
||
doi: 10.1186/s12967-023-04753-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38012642" target="_blank">38012642</a><a href="/pmc/articles/PMC10680259" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36879254">Identification of hub genes and potential molecular mechanisms related to radiotherapy sensitivity in rectal cancer based on multiple datasets.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao P,
|
||
Zhen H,
|
||
Zhao H,
|
||
Huang Y,
|
||
Cao B</span><br />
|
||
<span class="medgenPMjournal">J Transl Med</span>
|
||
2023 Mar 6;21(1):176.
|
||
doi: 10.1186/s12967-023-04029-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36879254" target="_blank">36879254</a><a href="/pmc/articles/PMC9987056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34531868">Pan-Cancer Analysis of PARP1 Alterations as Biomarkers in the Prediction of Immunotherapeutic Effects and the Association of Its Expression Levels and Immunotherapy Signatures.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang X,
|
||
Wang Y,
|
||
A G,
|
||
Qu C,
|
||
Chen J</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2021;12:721030.
|
||
Epub 2021 Aug 31
|
||
doi: 10.3389/fimmu.2021.721030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34531868" target="_blank">34531868</a><a href="/pmc/articles/PMC8438309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32903444">Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin A,
|
||
Zhang J,
|
||
Luo P</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2020;11:2039.
|
||
Epub 2020 Aug 12
|
||
doi: 10.3389/fimmu.2020.02039.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32903444" target="_blank">32903444</a><a href="/pmc/articles/PMC7435056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32482534">"Decision for adjuvant treatment in stage II colon cancer based on circulating tumor DNA:The CIRCULATE-PRODIGE 70 trial".</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Taïeb J,
|
||
Benhaim L,
|
||
Laurent Puig P,
|
||
Le Malicot K,
|
||
Emile JF,
|
||
Geillon F,
|
||
Tougeron D,
|
||
Manfredi S,
|
||
Chauvenet M,
|
||
Taly V,
|
||
Lepage C,
|
||
André T</span><br />
|
||
<span class="medgenPMjournal">Dig Liver Dis</span>
|
||
2020 Jul;52(7):730-733.
|
||
Epub 2020 May 29
|
||
doi: 10.1016/j.dld.2020.04.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32482534" target="_blank">32482534</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Rectum%20adenocarcinoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38012642">Research on radiotherapy related genes and prognostic target identification of rectal cancer based on multi-omics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu Y,
|
||
Yang Y,
|
||
Ni F,
|
||
Tai G,
|
||
Yu C,
|
||
Jiang X,
|
||
Wang D</span><br />
|
||
<span class="medgenPMjournal">J Transl Med</span>
|
||
2023 Nov 27;21(1):856.
|
||
doi: 10.1186/s12967-023-04753-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38012642" target="_blank">38012642</a><a href="/pmc/articles/PMC10680259" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36879254">Identification of hub genes and potential molecular mechanisms related to radiotherapy sensitivity in rectal cancer based on multiple datasets.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao P,
|
||
Zhen H,
|
||
Zhao H,
|
||
Huang Y,
|
||
Cao B</span><br />
|
||
<span class="medgenPMjournal">J Transl Med</span>
|
||
2023 Mar 6;21(1):176.
|
||
doi: 10.1186/s12967-023-04029-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36879254" target="_blank">36879254</a><a href="/pmc/articles/PMC9987056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36773567">MARCO is a potential prognostic and immunotherapy biomarker.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dong Q,
|
||
Zhang S,
|
||
Zhang H,
|
||
Sun J,
|
||
Lu J,
|
||
Wang G,
|
||
Wang X</span><br />
|
||
<span class="medgenPMjournal">Int Immunopharmacol</span>
|
||
2023 Mar;116:109783.
|
||
Epub 2023 Feb 9
|
||
doi: 10.1016/j.intimp.2023.109783.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36773567" target="_blank">36773567</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34531868">Pan-Cancer Analysis of PARP1 Alterations as Biomarkers in the Prediction of Immunotherapeutic Effects and the Association of Its Expression Levels and Immunotherapy Signatures.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang X,
|
||
Wang Y,
|
||
A G,
|
||
Qu C,
|
||
Chen J</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2021;12:721030.
|
||
Epub 2021 Aug 31
|
||
doi: 10.3389/fimmu.2021.721030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34531868" target="_blank">34531868</a><a href="/pmc/articles/PMC8438309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32903444">Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin A,
|
||
Zhang J,
|
||
Luo P</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2020;11:2039.
|
||
Epub 2020 Aug 12
|
||
doi: 10.3389/fimmu.2020.02039.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32903444" target="_blank">32903444</a><a href="/pmc/articles/PMC7435056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Rectum%20adenocarcinoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (72)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36879254">Identification of hub genes and potential molecular mechanisms related to radiotherapy sensitivity in rectal cancer based on multiple datasets.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao P,
|
||
Zhen H,
|
||
Zhao H,
|
||
Huang Y,
|
||
Cao B</span><br />
|
||
<span class="medgenPMjournal">J Transl Med</span>
|
||
2023 Mar 6;21(1):176.
|
||
doi: 10.1186/s12967-023-04029-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36879254" target="_blank">36879254</a><a href="/pmc/articles/PMC9987056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36773567">MARCO is a potential prognostic and immunotherapy biomarker.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dong Q,
|
||
Zhang S,
|
||
Zhang H,
|
||
Sun J,
|
||
Lu J,
|
||
Wang G,
|
||
Wang X</span><br />
|
||
<span class="medgenPMjournal">Int Immunopharmacol</span>
|
||
2023 Mar;116:109783.
|
||
Epub 2023 Feb 9
|
||
doi: 10.1016/j.intimp.2023.109783.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36773567" target="_blank">36773567</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36497135">The BRCAness Landscape of Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Guo M,
|
||
Wang SM</span><br />
|
||
<span class="medgenPMjournal">Cells</span>
|
||
2022 Dec 1;11(23)
|
||
doi: 10.3390/cells11233877.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36497135" target="_blank">36497135</a><a href="/pmc/articles/PMC9738094" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/34531868">Pan-Cancer Analysis of PARP1 Alterations as Biomarkers in the Prediction of Immunotherapeutic Effects and the Association of Its Expression Levels and Immunotherapy Signatures.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang X,
|
||
Wang Y,
|
||
A G,
|
||
Qu C,
|
||
Chen J</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2021;12:721030.
|
||
Epub 2021 Aug 31
|
||
doi: 10.3389/fimmu.2021.721030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34531868" target="_blank">34531868</a><a href="/pmc/articles/PMC8438309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/32903444">Crosstalk Between the MSI Status and Tumor Microenvironment in Colorectal Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin A,
|
||
Zhang J,
|
||
Luo P</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2020;11:2039.
|
||
Epub 2020 Aug 12
|
||
doi: 10.3389/fimmu.2020.02039.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32903444" target="_blank">32903444</a><a href="/pmc/articles/PMC7435056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Rectum%20adenocarcinoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (54)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/31061821">Prognostic Value of MicroRNA-15a in Human Cancers: A Meta-Analysis and Bioinformatics.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Yang FR,
|
||
Li HJ,
|
||
Li TT,
|
||
Zhao YF,
|
||
Liu ZK,
|
||
Li XR</span><br />
|
||
<span class="medgenPMjournal">Biomed Res Int</span>
|
||
2019;2019:2063823.
|
||
Epub 2019 Apr 2
|
||
doi: 10.1155/2019/2063823.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31061821" target="_blank">31061821</a><a href="/pmc/articles/PMC6466945" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Rectum%20adenocarcinoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
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