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<meta name="keywords" content="C0036220, african lymphadenopathic kaposi's sarcoma, hhv8, human herpesvirus 8, kaposi sarcoma, kaposi sarcoma herpesvirus, kaposi's sarcoma, kaposi's sarcoma (clinical), kaposi's sarcoma (disease), kaposi's sarcoma of conjunctiva, kaposi's sarcoma of cornea, kaposi's sarcoma of lung, kaposi's sarcoma of palate, kaposi's sarcoma of soft tissue, kaposi's sarcoma of soft tissues, kaposi's sarcoma-associated herpesvirus (kshv), kaposis sarcoma, ks, ks - kaposi's sarcoma, kshv, mediterranean kaposi sarcoma, multiple hemorrhagic sarcoma, multiple idiopathic pigmented hemangiosarcoma, neoplastic process, non aids related kaposi sarcoma, sarcoma, kaposi, sarcoma, kaposi's, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A systemic disease which can present with cutaneous lesions with or without internal involvement. Tumors are caused by Human herpesvirus 8 (HHV8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=11321
|
||
ConceptID=C0036220
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Kaposi sarcoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>11321</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0036220</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Kaposi's sarcoma; Kaposi's sarcoma (disease); Mediterranean Kaposi sarcoma</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>KS - Kaposi's sarcoma (109385007); Kaposi's sarcoma (clinical) (109385007); Kaposi's sarcoma (109385007); Kaposi sarcoma (109385007); Multiple hemorrhagic sarcoma (1179374007); Kaposi's sarcoma (1179374007); Kaposi sarcoma (1179374007)</td></tr>
|
||
<tr><td>Modes of inheritance:</td>
|
||
<td>
|
||
<div class="divPopper rprt" id="moi_988794"><div><strong>Not genetically inherited</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>988794</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms that cannot be identified in NLM's Unified Medical Language system (UMLS) Click for more information.">CN307044</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">clinical entity without genetic inheritance.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/988794">This record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_988794" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Not genetically inherited</a><span> (Orphanet)</span></div></td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help" data-jig="ncbipopper" href="#target-gene-related">Related genes:<img src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div id="target-gene-related" class="display-none">
|
||
Gene(s) associated with related conditions. For conditions<br />
|
||
in a hierarchy, the parent condition will list the genes<br />
|
||
associated with the children conditions.</div></td>
|
||
<td><a target="_blank" href="/gene/3569">IL6</a>, <a target="_blank" href="/gene/2186">BPTF</a></td></tr><tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0100726">HP:0100726</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0005055" target="_blank">MONDO:0005055</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=33276">ORPHA33276</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A systemic disease which can present with cutaneous lesions with or without internal involvement. Tumors are caused by Human herpesvirus 8 (HHV8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV). [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0036220[DISCUI]&test_type=Clinical" ref="ncbi_uid=11321">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=11321" ref="ncbi_uid=11321">V</a></span></span><span class="TLline">Kaposi sarcoma</span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=761233" target="_blank" href="/omim/147620">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=761233" ref="ncbi_uid=761233">V</a></span></span><span class="TLline"><a href="/medgen/761233" ref="tree=GTR&ncbi_uid=761233&link_uid=761233" title="View MedGen record for 'Kaposi sarcoma, susceptibility to'">Kaposi sarcoma, susceptibility to</a></span></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/19974" ref="tree=MeSH" title="MedGen record for Clinical finding">Clinical finding</a></span><ul><li><span class="TLline"><a href="/medgen/232191" ref="tree=MeSH" title="MedGen record for Finding by Cause">Finding by Cause</a></span><ul><li><span class="TLline"><a href="/medgen/811352" ref="tree=MeSH" title="MedGen record for Infection">Infection</a></span><ul><li><span class="TLline"><a href="/medgen/53027" ref="tree=MeSH" title="MedGen record for viral disease">viral disease</a></span><ul><li><span class="TLline"><a href="/medgen/41636" ref="tree=MeSH" title="MedGen record for DNA Virus Infections">DNA Virus Infections</a></span><ul><li><span class="TLline"><a href="/medgen/6823" ref="tree=MeSH" title="MedGen record for Herpesvirus infection">Herpesvirus infection</a></span><ul><li><span class="matched_ds">Kaposi sarcoma</span><ul><li><span class="TLline"><a href="/medgen/78817" ref="tree=MeSH" title="MedGen record for AIDS-Related Kaposi Sarcoma">AIDS-Related Kaposi Sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/234469" ref="tree=MeSH" title="MedGen record for AIDS-Related Cervical Kaposi Sarcoma">AIDS-Related Cervical Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/234470" ref="tree=MeSH" title="MedGen record for AIDS-Related Gastric Kaposi Sarcoma">AIDS-Related Gastric Kaposi Sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/232025" ref="tree=MeSH" title="MedGen record for Cardiac Kaposi Sarcoma">Cardiac Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/232677" ref="tree=MeSH" title="MedGen record for Central Nervous System Kaposi Sarcoma">Central Nervous System Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/91110" ref="tree=MeSH" title="MedGen record for Conjunctival Kaposi Sarcoma">Conjunctival Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/83430" ref="tree=MeSH" title="MedGen record for Corneal Kaposi Sarcoma">Corneal Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1757843" ref="tree=MeSH" title="MedGen record for Digestive System Kaposi Sarcoma">Digestive System Kaposi Sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/272307" ref="tree=MeSH" title="MedGen record for Anal Kaposi Sarcoma">Anal Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/474411" ref="tree=MeSH" title="MedGen record for Appendix Kaposi Sarcoma">Appendix Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/474466" ref="tree=MeSH" title="MedGen record for Colorectal Kaposi sarcoma">Colorectal Kaposi sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/232378" ref="tree=MeSH" title="MedGen record for Colon Kaposi sarcoma">Colon Kaposi sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/277575" ref="tree=MeSH" title="MedGen record for Rectum Kaposi sarcoma">Rectum Kaposi sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234230" ref="tree=MeSH" title="MedGen record for Esophageal Kaposi Sarcoma">Esophageal Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/473531" ref="tree=MeSH" title="MedGen record for Extrahepatic Bile Duct Kaposi Sarcoma">Extrahepatic Bile Duct Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/272659" ref="tree=MeSH" title="MedGen record for Gallbladder Kaposi Sarcoma">Gallbladder Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/232236" ref="tree=MeSH" title="MedGen record for Gastric Kaposi Sarcoma">Gastric Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/473527" ref="tree=MeSH" title="MedGen record for Liver Kaposi Sarcoma">Liver Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/474159" ref="tree=MeSH" title="MedGen record for Small Intestinal Kaposi Sarcoma">Small Intestinal Kaposi Sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/232453" ref="tree=MeSH" title="MedGen record for Endemic African Kaposi Sarcoma">Endemic African Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/235203" ref="tree=MeSH" title="MedGen record for Iatrogenic Kaposi sarcoma">Iatrogenic Kaposi sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/78932" ref="tree=MeSH" title="MedGen record for Kaposi Sarcoma Related to Immunosuppressive Treatment">Kaposi Sarcoma Related to Immunosuppressive Treatment</a></span><ul><li><span class="TLline"><a href="/medgen/277832" ref="tree=MeSH" title="MedGen record for Transplant-Related Kaposi Sarcoma">Transplant-Related Kaposi Sarcoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/272784" ref="tree=MeSH" title="MedGen record for Kaposi Sarcoma NCI Grade 2">Kaposi Sarcoma NCI Grade 2</a></span></li><li><span class="TLline"><a href="/medgen/235241" ref="tree=MeSH" title="MedGen record for Kaposi Sarcoma NCI Grade 3">Kaposi Sarcoma NCI Grade 3</a></span></li><li><span class="TLline"><a href="/medgen/761233" ref="tree=MeSH" title="MedGen record for Kaposi sarcoma, susceptibility to">Kaposi sarcoma, susceptibility to</a></span></li><li><span class="TLline"><a href="/medgen/57790" ref="tree=MeSH" title="MedGen record for Lung Kaposi Sarcoma">Lung Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233630" ref="tree=MeSH" title="MedGen record for Lymphadenopathic Kaposi Sarcoma">Lymphadenopathic Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/721119" ref="tree=MeSH" title="MedGen record for Metastatic Kaposi Sarcoma">Metastatic Kaposi Sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/1650954" ref="tree=MeSH" title="MedGen record for Advanced Kaposi Sarcoma">Advanced Kaposi Sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1761543" ref="tree=MeSH" title="MedGen record for Oral Cavity Kaposi Sarcoma">Oral Cavity Kaposi Sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/57789" ref="tree=MeSH" title="MedGen record for Palate Kaposi Sarcoma">Palate Kaposi Sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233313" ref="tree=MeSH" title="MedGen record for Parotid Gland Kaposi Sarcoma">Parotid Gland Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233320" ref="tree=MeSH" title="MedGen record for Penile Kaposi Sarcoma">Penile Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233874" ref="tree=MeSH" title="MedGen record for Prostate Kaposi Sarcoma">Prostate Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/124564" ref="tree=MeSH" title="MedGen record for Recurrent Kaposi Sarcoma">Recurrent Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1670331" ref="tree=MeSH" title="MedGen record for Refractory Kaposi Sarcoma">Refractory Kaposi Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/57563" ref="tree=MeSH" title="MedGen record for Skin Kaposi Sarcoma">Skin Kaposi Sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/78931" ref="tree=MeSH" title="MedGen record for Classic Kaposi sarcoma">Classic Kaposi sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1793820" ref="tree=MeSH" title="MedGen record for Vulvar Kaposi Sarcoma">Vulvar Kaposi Sarcoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=10316&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Kaposi sarcoma</span> in Orphanet.</div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_440575"><div><strong>Combined immunodeficiency due to STIM1 deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>440575</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2748557</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-10 (IMD10) is an autosomal recessive primary immunodeficiency characterized by onset of recurrent infections in childhood due to defective T- and NK-cell function, although the severity is variable. Affected individuals may also have hypotonia, hypohidrosis, or dental enamel hypoplasia consistent with amelogenesis imperfecta (summary by Parry et al., 2016).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/440575">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_761233"><div><strong>Kaposi sarcoma, susceptibility to</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>761233</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3538945</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Kaposi sarcoma (KS) is a rare neoplasm that shows sporadic, endemic, and epidemic forms. KS usually presents with purplish papular cutaneous lesions often on the lower limbs, back, and mouth, but may also involve the gastrointestinal and respiratory systems. KS is caused by an infectious agent, Kaposi sarcoma-associated herpesvirus (KSHV; human herpesvirus-8, HHV-8). KSHV infection is necessary but not sufficient for KS development; the infection is mostly asymptomatic but may cause disease in immunocompromised patients (summary by Yogev et al., 2024). KS is an invasive angioproliferative inflammatory condition that occurs commonly in men infected with human immunodeficiency virus (HIV; see 609423). In the early stages of KS, lesions appear reactive and are stimulated to grow by the actions of inflammatory cytokines and growth factors. In the late stages of KS, a malignant phenotype that appears to be monoclonal can develop. Coinfection with HIV markedly increases the likelihood of KS development, and additional environmental, hormonal, and genetic cofactors likely contribute to its pathogenesis (summary by Foster et al., 2000). Suthaus et al. (2012) noted that HHV-8 is the etiologic agent not only of KS, but also of primary effusion lymphoma and plasma cell-type multicentric Castleman disease (MCD).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/761233">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_816383"><div><strong>Combined immunodeficiency due to OX40 deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816383</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3810053</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-16 (IMD16) is an autosomal recessive primary immunodeficiency associated with classic Kaposi sarcoma of childhood and poor T-cell recall immune responses due to complete functional OX40 deficiency (Byun et al., 2013).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/816383">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816383" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Combined immunodeficiency due to OX40 deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_440575" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Combined immunodeficiency due to STIM1 deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_761233" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Kaposi sarcoma, susceptibility to</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38551777">Differential diagnosis between kaposi sarcoma-associated herpesvirus cytokine syndrome and hemophagocytic lymphohistiocytosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Luppi M,
|
||
Cona A,
|
||
Barozzi P,
|
||
Riva G,
|
||
Mularoni A</span><br />
|
||
<span class="medgenPMjournal">Infection</span>
|
||
2024 Aug;52(4):1643-1644.
|
||
Epub 2024 Mar 29
|
||
doi: 10.1007/s15010-024-02252-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38551777" target="_blank">38551777</a><a href="/pmc/articles/PMC11289136" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37578202">Clinical management of Kaposi sarcoma herpesvirus-associated diseases: an update on disease manifestations and treatment strategies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Patel R,
|
||
Lurain K,
|
||
Yarchoan R,
|
||
Ramaswami R</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Anti Infect Ther</span>
|
||
2023 Jul-Dec;21(9):929-941.
|
||
Epub 2023 Aug 15
|
||
doi: 10.1080/14787210.2023.2247161.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37578202" target="_blank">37578202</a><a href="/pmc/articles/PMC10529793" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28324233">Diagnosis and Treatment of Kaposi Sarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schneider JW,
|
||
Dittmer DP</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Dermatol</span>
|
||
2017 Aug;18(4):529-539.
|
||
doi: 10.1007/s40257-017-0270-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28324233" target="_blank">28324233</a><a href="/pmc/articles/PMC5509489" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22kaposi%20sarcoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (129)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/kaposi.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Kaposi Sarcoma, 2023</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36410975">Cutaneous Oncology in the Immunosuppressed.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang LL,
|
||
Lin SK,
|
||
Stull CM,
|
||
Shin TM,
|
||
Higgins HW,
|
||
Giordano CN,
|
||
McMurray SL,
|
||
Etzkorn JR,
|
||
Miller CJ,
|
||
Walker JL</span><br />
|
||
<span class="medgenPMjournal">Dermatol Clin</span>
|
||
2023 Jan;41(1):141-162.
|
||
doi: 10.1016/j.det.2022.07.012.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36410975" target="_blank">36410975</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30601874">Oral Kaposi Sarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sanchez IM,
|
||
DiTommaso LE,
|
||
Tsoukas MM</span><br />
|
||
<span class="medgenPMjournal">JAMA Dermatol</span>
|
||
2019 Mar 1;155(3):370.
|
||
doi: 10.1001/jamadermatol.2018.4079.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30601874" target="_blank">30601874</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29539283">HIV-Associated Cancers and Related Diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yarchoan R,
|
||
Uldrick TS</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2018 Mar 15;378(11):1029-1041.
|
||
doi: 10.1056/NEJMra1615896.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29539283" target="_blank">29539283</a><a href="/pmc/articles/PMC6890231" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28324233">Diagnosis and Treatment of Kaposi Sarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schneider JW,
|
||
Dittmer DP</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Dermatol</span>
|
||
2017 Aug;18(4):529-539.
|
||
doi: 10.1007/s40257-017-0270-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28324233" target="_blank">28324233</a><a href="/pmc/articles/PMC5509489" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10749966">Kaposi's sarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Antman K,
|
||
Chang Y</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2000 Apr 6;342(14):1027-38.
|
||
doi: 10.1056/NEJM200004063421407.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10749966" target="_blank">10749966</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Kaposi%20sarcoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2728)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37040901">Anaplastic Kaposi sarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Legesse TB,
|
||
Twaddell WS,
|
||
Ng VY,
|
||
Davis DL,
|
||
Ciner AT,
|
||
Kallen ME</span><br />
|
||
<span class="medgenPMjournal">Histopathology</span>
|
||
2023 Jul;83(1):149-150.
|
||
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<div class="nl"><a target="_blank" href="/pubmed/30521465">African Kaposi's Sarcoma.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28324233">Diagnosis and Treatment of Kaposi Sarcoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Schneider JW,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Kaposi%20sarcoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1994)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/35491643">Pembrolizumab Is Safe and Effective in Kaposi Sarcoma.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Kaposi%20sarcoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1508)</a></div></div>
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</div>
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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<div class="nl"><a target="_blank" href="/pubmed/38049836">Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35671149">Kaposi Sarcoma of the Larynx: A Systematic Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Barron K,
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Omiunu A,
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Celidonio J,
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Cruz-Mullane A,
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Din-Lovinescu C,
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Chemas-Velez MM,
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<div class="nl"><a target="_blank" href="/pubmed/35775738">Treatments for AIDS/HIV-related Kaposi sarcoma: A systematic review of the literature.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Liew YCC,
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Tam YCS,
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<span class="bold">PMID: </span><a href="/pubmed/35775738" target="_blank">35775738</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35085400">Burden of Kaposi sarcoma according to HIV status: A systematic review and global analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ibrahim Khalil A,
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<div class="nl"><a target="_blank" href="/pubmed/22157133">Multicentric Castleman disease in an HHV8-infected child born to consanguineous parents with systematic review.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Kaposi%20sarcoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (40)</a></div></div>
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||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
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|
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</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
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<div class="rightCol mgCol">
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0036220%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0036220%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (3)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0036220%5bDISCUI%5d" target="_blank">See all (3)</a></total></li>
|
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</ul></div>
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</div>
|
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<div class="portlet mgSection" id="ID_119">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=33276" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Kaposi%20sarcoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
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|
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|
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