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<meta name="keywords" content="C0023269, leiomyosarcoma, leiomyosarcoma (excluding uterine leiomyosarcoma), leiomyosarcoma - not uterine, leiomyosarcoma, malignant, leiomyosarcomas, neoplastic process, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A smooth muscle connective tissue tumor, which is rare type of cancer that is a malignant neoplasm of smooth muscle. When such a neoplasm is benign, it is called a leiomyoma." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=9711
|
||
ConceptID=C0023269
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Leiomyosarcoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>9711</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0023269</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Leiomyosarcomas</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Leiomyosarcoma (443719001); Leiomyosarcoma (1163022006)</td></tr>
|
||
<tr><td>Modes of inheritance:</td>
|
||
<td>
|
||
<div class="divPopper rprt" id="moi_988794"><div><strong>Not genetically inherited</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>988794</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms that cannot be identified in NLM's Unified Medical Language system (UMLS) Click for more information.">CN307044</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">clinical entity without genetic inheritance.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/988794">This record</a></div></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_988794" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Not genetically inherited</a><span> (Orphanet)</span></div></td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0100243">HP:0100243</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0005058" target="_blank">MONDO:0005058</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=64720">ORPHA64720</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A smooth muscle connective tissue tumor, which is rare type of cancer that is a malignant neoplasm of smooth muscle. When such a neoplasm is benign, it is called a leiomyoma. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Leiomyosarcoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1843096" ref="tree=MeSH" title="MedGen record for Epstein-Barr virus-associated mesenchymal tumor">Epstein-Barr virus-associated mesenchymal tumor</a></span><ul><li><span class="matched_ds">Leiomyosarcoma</span><ul><li><span class="TLline"><a href="/medgen/124483" ref="tree=MeSH" title="MedGen record for Adult Leiomyosarcoma">Adult Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1704193" ref="tree=MeSH" title="MedGen record for Bladder Leiomyosarcoma">Bladder Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/234043" ref="tree=MeSH" title="MedGen record for Bone leiomyosarcoma">Bone leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/234050" ref="tree=MeSH" title="MedGen record for Breast leiomyosarcoma">Breast leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1792392" ref="tree=MeSH" title="MedGen record for Broad Ligament Leiomyosarcoma">Broad Ligament Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/235254" ref="tree=MeSH" title="MedGen record for Central nervous system leiomyosarcoma">Central nervous system leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/76054" ref="tree=MeSH" title="MedGen record for Childhood Leiomyosarcoma">Childhood Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/904885" ref="tree=MeSH" title="MedGen record for Childhood Small Intestinal Leiomyosarcoma">Childhood Small Intestinal Leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1783758" ref="tree=MeSH" title="MedGen record for Conjunctival Leiomyosarcoma">Conjunctival Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/232394" ref="tree=MeSH" title="MedGen record for Conventional leiomyosarcoma">Conventional leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/87534" ref="tree=MeSH" title="MedGen record for Cutaneous leiomyosarcoma">Cutaneous leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1748737" ref="tree=MeSH" title="MedGen record for Digestive System Leiomyosarcoma">Digestive System Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/231370" ref="tree=MeSH" title="MedGen record for Anus leiomyosarcoma">Anus leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/473538" ref="tree=MeSH" title="MedGen record for Appendix Leiomyosarcoma">Appendix Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/474465" ref="tree=MeSH" title="MedGen record for Colorectal Leiomyosarcoma">Colorectal Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/232380" ref="tree=MeSH" title="MedGen record for Colon leiomyosarcoma">Colon leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233391" ref="tree=MeSH" title="MedGen record for Rectum leiomyosarcoma">Rectum leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272589" ref="tree=MeSH" title="MedGen record for Esophagus leiomyosarcoma">Esophagus leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/232481" ref="tree=MeSH" title="MedGen record for Extrahepatic bile duct leiomyosarcoma">Extrahepatic bile duct leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/234291" ref="tree=MeSH" title="MedGen record for Gallbladder leiomyosarcoma">Gallbladder leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/196652" ref="tree=MeSH" title="MedGen record for Gastric leiomyosarcoma">Gastric leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/272707" ref="tree=MeSH" title="MedGen record for Liver leiomyosarcoma">Liver leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/183086" ref="tree=MeSH" title="MedGen record for Small intestine leiomyosarcoma">Small intestine leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1700409" ref="tree=MeSH" title="MedGen record for EBV-Related Leiomyosarcoma">EBV-Related Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/61454" ref="tree=MeSH" title="MedGen record for Epithelioid leiomyosarcoma">Epithelioid leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/274363" ref="tree=MeSH" title="MedGen record for Uterine corpus epithelioid leiomyosarcoma">Uterine corpus epithelioid leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/274488" ref="tree=MeSH" title="MedGen record for Fallopian tube leiomyosarcoma">Fallopian tube leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/234321" ref="tree=MeSH" title="MedGen record for Granular cell leiomyosarcoma">Granular cell leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/234095" ref="tree=MeSH" title="MedGen record for Heart leiomyosarcoma">Heart leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233554" ref="tree=MeSH" title="MedGen record for Inflammatory leiomyosarcoma">Inflammatory leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/235545" ref="tree=MeSH" title="MedGen record for Kidney leiomyosarcoma">Kidney leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/272791" ref="tree=MeSH" title="MedGen record for Laryngeal leiomyosarcoma">Laryngeal leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/232696" ref="tree=MeSH" title="MedGen record for Leiomyosarcoma NCI Grade 2">Leiomyosarcoma NCI Grade 2</a></span></li><li><span class="TLline"><a href="/medgen/233612" ref="tree=MeSH" title="MedGen record for Leiomyosarcoma NCI Grade 3">Leiomyosarcoma NCI Grade 3</a></span></li><li><span class="TLline"><a href="/medgen/882471" ref="tree=MeSH" title="MedGen record for Leiomyosarcoma of Deep Soft Tissue">Leiomyosarcoma of Deep Soft Tissue</a></span><ul><li><span class="TLline"><a href="/medgen/412162" ref="tree=MeSH" title="MedGen record for Retroperitoneal leiomyosarcoma">Retroperitoneal leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/927349" ref="tree=MeSH" title="MedGen record for Leiomyosarcoma of the cervix uteri">Leiomyosarcoma of the cervix uteri</a></span></li><li><span class="TLline"><a href="/medgen/277864" ref="tree=MeSH" title="MedGen record for Leiomyosarcoma of Vessels">Leiomyosarcoma of Vessels</a></span><ul><li><span class="TLline"><a href="/medgen/272756" ref="tree=MeSH" title="MedGen record for Inferior Vena Cava Leiomyosarcoma">Inferior Vena Cava Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233372" ref="tree=MeSH" title="MedGen record for Pulmonary artery leiomyosarcoma">Pulmonary artery leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/235513" ref="tree=MeSH" title="MedGen record for Pulmonary vein leiomyosarcoma">Pulmonary vein leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/277592" ref="tree=MeSH" title="MedGen record for Renal Vein Leiomyosarcoma">Renal Vein Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/236963" ref="tree=MeSH" title="MedGen record for Superior vena cava leiomyosarcoma">Superior vena cava leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163507" ref="tree=MeSH" title="MedGen record for Localized Leiomyosarcoma">Localized Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/232711" ref="tree=MeSH" title="MedGen record for Lung leiomyosarcoma">Lung leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/235310" ref="tree=MeSH" title="MedGen record for Mediastinum leiomyosarcoma">Mediastinum leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/163506" ref="tree=MeSH" title="MedGen record for Metastatic Leiomyosarcoma">Metastatic Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/1714364" ref="tree=MeSH" title="MedGen record for Advanced Leiomyosarcoma">Advanced Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/1718848" ref="tree=MeSH" title="MedGen record for Advanced Soft Tissue Leiomyosarcoma">Advanced Soft Tissue Leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1702008" ref="tree=MeSH" title="MedGen record for Locally Advanced Leiomyosarcoma">Locally Advanced Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1714888" ref="tree=MeSH" title="MedGen record for Metastatic Soft Tissue Leiomyosarcoma">Metastatic Soft Tissue Leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/104725" ref="tree=MeSH" title="MedGen record for Myxoid leiomyosarcoma">Myxoid leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/311426" ref="tree=MeSH" title="MedGen record for Uterine corpus myxoid leiomyosarcoma">Uterine corpus myxoid leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233275" ref="tree=MeSH" title="MedGen record for Ovary leiomyosarcoma">Ovary leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1699937" ref="tree=MeSH" title="MedGen record for Paratesticular Leiomyosarcoma">Paratesticular Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/1691073" ref="tree=MeSH" title="MedGen record for Seminal Vesicle Leiomyosarcoma">Seminal Vesicle Leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1688881" ref="tree=MeSH" title="MedGen record for Penile Leiomyosarcoma">Penile Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1790039" ref="tree=MeSH" title="MedGen record for Pleomorphic Leiomyosarcoma">Pleomorphic Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/1791315" ref="tree=MeSH" title="MedGen record for Dedifferentiated Leiomyosarcoma">Dedifferentiated Leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233876" ref="tree=MeSH" title="MedGen record for Prostate leiomyosarcoma">Prostate leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/163508" ref="tree=MeSH" title="MedGen record for Recurrent Leiomyosarcoma">Recurrent Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/1791953" ref="tree=MeSH" title="MedGen record for Locally Recurrent Uterine Corpus Leiomyosarcoma">Locally Recurrent Uterine Corpus Leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1652428" ref="tree=MeSH" title="MedGen record for Refractory Leiomyosarcoma">Refractory Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1780623" ref="tree=MeSH" title="MedGen record for Resectable Leiomyosarcoma">Resectable Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1733090" ref="tree=MeSH" title="MedGen record for Sinonasal Leiomyosarcoma">Sinonasal Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1654933" ref="tree=MeSH" title="MedGen record for Thyroid Gland Leiomyosarcoma">Thyroid Gland Leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1385549" ref="tree=MeSH" title="MedGen record for Unresectable Leiomyosarcoma">Unresectable Leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/1713501" ref="tree=MeSH" title="MedGen record for Unresectable Soft Tissue Leiomyosarcoma">Unresectable Soft Tissue Leiomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83679" ref="tree=MeSH" title="MedGen record for Uterine leiomyosarcoma">Uterine leiomyosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/1633243" ref="tree=MeSH" title="MedGen record for Uterine Corpus Leiomyosarcoma by AJCC v8 Stage">Uterine Corpus Leiomyosarcoma by AJCC v8 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1645980" ref="tree=MeSH" title="MedGen record for Stage I Uterine Corpus Leiomyosarcoma AJCC v8">Stage I Uterine Corpus Leiomyosarcoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1639799" ref="tree=MeSH" title="MedGen record for Stage II Uterine Corpus Leiomyosarcoma AJCC v8">Stage II Uterine Corpus Leiomyosarcoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1637724" ref="tree=MeSH" title="MedGen record for Stage III Uterine Corpus Leiomyosarcoma AJCC v8">Stage III Uterine Corpus Leiomyosarcoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1646588" ref="tree=MeSH" title="MedGen record for Stage IV Uterine Corpus Leiomyosarcoma AJCC v8">Stage IV Uterine Corpus Leiomyosarcoma AJCC v8</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/277860" ref="tree=MeSH" title="MedGen record for Vagina leiomyosarcoma">Vagina leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/378348" ref="tree=MeSH" title="MedGen record for Vulvar leiomyosarcoma">Vulvar leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/237060" ref="tree=MeSH" title="MedGen record for Well Differentiated Leiomyosarcoma">Well Differentiated Leiomyosarcoma</a></span></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=10838&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Leiomyosarcoma</span> in Orphanet.</div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36194109">MRI Evaluation of Uterine Masses for Risk of Leiomyosarcoma: A Consensus Statement.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hindman N,
|
||
Kang S,
|
||
Fournier L,
|
||
Lakhman Y,
|
||
Nougaret S,
|
||
Reinhold C,
|
||
Sadowski E,
|
||
Huang JQ,
|
||
Ascher S</span><br />
|
||
<span class="medgenPMjournal">Radiology</span>
|
||
2023 Feb;306(2):e211658.
|
||
Epub 2022 Oct 4
|
||
doi: 10.1148/radiol.211658.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36194109" target="_blank">36194109</a><a href="/pmc/articles/PMC9885356" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35715148">Leiomyosarcoma: Current Clinical Management and Future Horizons.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Devaud N,
|
||
Vornicova O,
|
||
Abdul Razak AR,
|
||
Khalili K,
|
||
Demicco EG,
|
||
Mitric C,
|
||
Bernardini MQ,
|
||
Gladdy RA</span><br />
|
||
<span class="medgenPMjournal">Surg Oncol Clin N Am</span>
|
||
2022 Jul;31(3):527-546.
|
||
doi: 10.1016/j.soc.2022.03.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35715148" target="_blank">35715148</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32914475">Retroperitoneal tumors: Review of diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sassa N</span><br />
|
||
<span class="medgenPMjournal">Int J Urol</span>
|
||
2020 Dec;27(12):1058-1070.
|
||
Epub 2020 Sep 10
|
||
doi: 10.1111/iju.14361.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32914475" target="_blank">32914475</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22leiomyosarcoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (308)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/sarcoma.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Soft Tissue Sarcoma, 2024</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36975422">Management of Recurrent Retroperitoneal Sarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jolissaint JS,
|
||
Raut CP,
|
||
Fairweather M</span><br />
|
||
<span class="medgenPMjournal">Curr Oncol</span>
|
||
2023 Feb 25;30(3):2761-2769.
|
||
doi: 10.3390/curroncol30030209.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36975422" target="_blank">36975422</a><a href="/pmc/articles/PMC10047230" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36135073">Updates in Pathology for Retroperitoneal Soft Tissue Sarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mack T,
|
||
Purgina B</span><br />
|
||
<span class="medgenPMjournal">Curr Oncol</span>
|
||
2022 Sep 7;29(9):6400-6418.
|
||
doi: 10.3390/curroncol29090504.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36135073" target="_blank">36135073</a><a href="/pmc/articles/PMC9497884" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33602520">Cutaneous Sarcomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tillman BN,
|
||
Liu JC</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Clin North Am</span>
|
||
2021 Apr;54(2):369-378.
|
||
Epub 2021 Feb 16
|
||
doi: 10.1016/j.otc.2020.11.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33602520" target="_blank">33602520</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30321869">Uterine Leiomyosarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Juhasz-Böss I,
|
||
Gabriel L,
|
||
Bohle RM,
|
||
Horn LC,
|
||
Solomayer EF,
|
||
Breitbach GP</span><br />
|
||
<span class="medgenPMjournal">Oncol Res Treat</span>
|
||
2018;41(11):680-686.
|
||
Epub 2018 Oct 16
|
||
doi: 10.1159/000494299.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30321869" target="_blank">30321869</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11884817">Cutaneous leiomyosarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Porter CJ,
|
||
Januszkiewicz JS</span><br />
|
||
<span class="medgenPMjournal">Plast Reconstr Surg</span>
|
||
2002 Mar;109(3):964-7.
|
||
doi: 10.1097/00006534-200203000-00024.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11884817" target="_blank">11884817</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Leiomyosarcoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2504)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35715148">Leiomyosarcoma: Current Clinical Management and Future Horizons.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Devaud N,
|
||
Vornicova O,
|
||
Abdul Razak AR,
|
||
Khalili K,
|
||
Demicco EG,
|
||
Mitric C,
|
||
Bernardini MQ,
|
||
Gladdy RA</span><br />
|
||
<span class="medgenPMjournal">Surg Oncol Clin N Am</span>
|
||
2022 Jul;31(3):527-546.
|
||
doi: 10.1016/j.soc.2022.03.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35715148" target="_blank">35715148</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30207938">Growth Patterns of Retroperitoneal Leiomyosarcomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Frazier AA</span><br />
|
||
<span class="medgenPMjournal">Radiographics</span>
|
||
2018 Sep-Oct;38(5):1402.
|
||
doi: 10.1148/rg.2018184006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30207938" target="_blank">30207938</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27617944">Primary periungual leiyomyosarcoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rachadi H,
|
||
Derrabi N,
|
||
Marnissi F,
|
||
Chiheb S</span><br />
|
||
<span class="medgenPMjournal">Dermatol Online J</span>
|
||
2016 Aug 15;22(8)
|
||
<span class="bold">PMID: </span><a href="/pubmed/27617944" target="_blank">27617944</a></div>
|
||
|
||
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</div>
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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<div class="nl"><a target="_blank" href="/pubmed/37814590">Leiomyosarcoma of the rectum: A systematic review of recent literature.</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/37814590" target="_blank">37814590</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/37301271">Special features of sarcomas developed in patients with Lynch syndrome: A systematic review.</a></div>
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Jaffrelot M,
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<div class="portlet_content ln"><span class="medgenPMauthor">Li Y,
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<div class="portlet_content ln"><span class="medgenPMauthor">Sparić R,
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<div class="nl"><a target="_blank" href="/pubmed/34624740">Ki67 as a prognostic marker in uterine leiomyosarcoma: A quantitative systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Travaglino A,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Leiomyosarcoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (64)</a></div></div>
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||
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|
||
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|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=64720" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Leiomyosarcoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22leiomyosarcoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Leiomyosarcoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/sarcoma.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Soft Tissue Sarcoma, 2024</div></li></ul></div>
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