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<meta name="keywords" content="C0004114, astrocytic glioma, astrocytic gliomas, astrocytic neoplasm, astrocytic tumor, astrocytoma, astrocytoma (excluding glioblastoma), astrocytomas, astroglioma, astrogliomas, glioma, astrocytic, gliomas, astrocytic, neoplastic process, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Astrocytoma is a neoplasm of the central nervous system derived from astrocytes. Astrocytes are a type of glial cell, and thus astrocytoma is a subtype of glioma." /><meta name="robots" content="index,nofollow,noarchive" />
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|
||
<!--
|
||
UID=438
|
||
ConceptID=C0004114
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Astrocytoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>438</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0004114</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Astrocytoma (excluding glioblastoma)</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Astrocytoma (1157043006); Astrocytic glioma (1157043006); Astroglioma (1157043006)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0009592">HP:0009592</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0019781" target="_blank">MONDO:0019781</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/137800" target="_blank">137800</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Astrocytoma is a neoplasm of the central nervous system derived from astrocytes. Astrocytes are a type of glial cell, and thus astrocytoma is a subtype of glioma. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
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|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0017638[DISCUI]&test_type=Clinical" ref="ncbi_uid=9030">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=9030" ref="ncbi_uid=9030">V</a></span></span><span class="TLline"><a href="/medgen/9030" ref="tree=GTR&ncbi_uid=9030&link_uid=9030" title="View MedGen record for 'Glioma'">Glioma</a></span><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0004114[DISCUI]&test_type=Clinical" ref="ncbi_uid=438">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=438" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=438" ref="ncbi_uid=438">V</a></span></span><span class="TLline">Astrocytoma</span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0017636[DISCUI]&test_type=Clinical" ref="ncbi_uid=42228">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C0017636[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=42228">R</a></span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=42228" ref="ncbi_uid=42228">V</a></span></span><span class="TLline"><a href="/medgen/42228" ref="tree=GTR&ncbi_uid=42228&link_uid=42228" title="View MedGen record for 'Glioblastoma'">Glioblastoma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0014474[DISCUI]&test_type=Clinical" ref="ncbi_uid=41825">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=41825" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=41825" ref="ncbi_uid=41825">V</a></span></span><span class="TLline"><a href="/medgen/41825" ref="tree=GTR&ncbi_uid=41825&link_uid=41825" title="View MedGen record for 'Ependymoma'">Ependymoma</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=64637" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/64637" ref="tree=GTR&ncbi_uid=64637&link_uid=64637" title="View MedGen record for 'Subependymal glioma'">Subependymal glioma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=CN305335[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=986435">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/986435" ref="tree=GTR&ncbi_uid=986435&link_uid=986435" title="View MedGen record for 'Glioma susceptibility'">Glioma susceptibility</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C2750850[DISCUI]&test_type=Clinical" ref="ncbi_uid=413414">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=413414" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=413414" ref="ncbi_uid=413414">V</a></span></span><span class="TLline"><a href="/medgen/413414" ref="tree=GTR&ncbi_uid=413414&link_uid=413414" title="View MedGen record for 'Glioma susceptibility 1'">Glioma susceptibility 1</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0025149[DISCUI]&test_type=Clinical" ref="ncbi_uid=7517">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=7517" target="_blank" href="/omim/155255">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=7517" ref="ncbi_uid=7517">V</a></span></span><span class="TLline"><a href="/medgen/7517" ref="tree=GTR&ncbi_uid=7517&link_uid=7517" title="View MedGen record for 'Medulloblastoma'">Medulloblastoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0547065[DISCUI]&test_type=Clinical" ref="ncbi_uid=154285">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/154285" ref="tree=GTR&ncbi_uid=154285&link_uid=154285" title="View MedGen record for 'Oligoastrocytoma'">Oligoastrocytoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0028945[DISCUI]&test_type=Clinical" ref="ncbi_uid=45190">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=45190" target="_blank" href="/omim/137800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=45190" ref="ncbi_uid=45190">V</a></span></span><span class="TLline"><a href="/medgen/45190" ref="tree=GTR&ncbi_uid=45190&link_uid=45190" title="View MedGen record for 'Oligodendroglioma'">Oligodendroglioma</a></span></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1254" ref="tree=MeSH" title="MedGen record for Fetal anomaly">Fetal anomaly</a></span><ul><li><span class="TLline"><a href="/medgen/474891" ref="tree=MeSH" title="MedGen record for Congenital Systemic Disorder">Congenital Systemic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868416" ref="tree=MeSH" title="MedGen record for Abnormal nervous system morphology">Abnormal nervous system morphology</a></span><ul><li><span class="TLline"><a href="/medgen/867607" ref="tree=MeSH" title="MedGen record for Abnormal glial cell morphology">Abnormal glial cell morphology</a></span><ul><li><span class="TLline"><a href="/medgen/867605" ref="tree=MeSH" title="MedGen record for Abnormal astrocyte morphology">Abnormal astrocyte morphology</a></span><ul><li><span class="matched_ds">Astrocytoma</span><ul><li><span class="TLline"><a href="/medgen/272290" ref="tree=MeSH" title="MedGen record for Adult astrocytic tumor">Adult astrocytic tumor</a></span><ul><li><span class="TLline"><a href="/medgen/233962" ref="tree=MeSH" title="MedGen record for Adult brainstem astrocytoma">Adult brainstem astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/79278" ref="tree=MeSH" title="MedGen record for Adult infiltrating astrocytic neoplasm">Adult infiltrating astrocytic neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/76118" ref="tree=MeSH" title="MedGen record for Adult Anaplastic Astrocytoma">Adult Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/272295" ref="tree=MeSH" title="MedGen record for Adult Diffuse Astrocytoma">Adult Diffuse Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/124527" ref="tree=MeSH" title="MedGen record for Adult glioblastoma">Adult glioblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/128889" ref="tree=MeSH" title="MedGen record for Adult Pilocytic Astrocytoma">Adult Pilocytic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/859690" ref="tree=MeSH" title="MedGen record for Adult Pineal Gland Astrocytoma">Adult Pineal Gland Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/321874" ref="tree=MeSH" title="MedGen record for Adult Subependymal Giant Cell Astrocytoma">Adult Subependymal Giant Cell Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/924393" ref="tree=MeSH" title="MedGen record for Anaplastic pleomorphic xanthoastrocytoma">Anaplastic pleomorphic xanthoastrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/1685266" ref="tree=MeSH" title="MedGen record for Recurrent Anaplastic Pleomorphic Xanthoastrocytoma">Recurrent Anaplastic Pleomorphic Xanthoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1701639" ref="tree=MeSH" title="MedGen record for Refractory Anaplastic Pleomorphic Xanthoastrocytoma">Refractory Anaplastic Pleomorphic Xanthoastrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/137784" ref="tree=MeSH" title="MedGen record for Astrocytoma, anaplastic">Astrocytoma, anaplastic</a></span><ul><li><span class="TLline"><a href="/medgen/927512" ref="tree=MeSH" title="MedGen record for Anaplastic Astrocytoma, IDH-Wildtype">Anaplastic Astrocytoma, IDH-Wildtype</a></span></li><li><span class="TLline"><a href="/medgen/233983" ref="tree=MeSH" title="MedGen record for Anaplastic Brain Stem Astrocytoma">Anaplastic Brain Stem Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/231068" ref="tree=MeSH" title="MedGen record for Anaplastic Diencephalic Astrocytoma">Anaplastic Diencephalic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/927513" ref="tree=MeSH" title="MedGen record for Astrocytoma, IDH-mutant, grade 3">Astrocytoma, IDH-mutant, grade 3</a></span></li><li><span class="TLline"><a href="/medgen/1635918" ref="tree=MeSH" title="MedGen record for Childhood Anaplastic Astrocytoma">Childhood Anaplastic Astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/234121" ref="tree=MeSH" title="MedGen record for Childhood Brain Anaplastic Astrocytoma">Childhood Brain Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/857356" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Anaplastic Astrocytoma">Recurrent Childhood Anaplastic Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/231069" ref="tree=MeSH" title="MedGen record for Hemispheric Anaplastic Astrocytoma">Hemispheric Anaplastic Astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/859264" ref="tree=MeSH" title="MedGen record for Childhood Cerebral Anaplastic Astrocytoma">Childhood Cerebral Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1660962" ref="tree=MeSH" title="MedGen record for Frontal Lobe Anaplastic Astrocytoma">Frontal Lobe Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1721747" ref="tree=MeSH" title="MedGen record for Parietal Lobe Anaplastic Astrocytoma">Parietal Lobe Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1659216" ref="tree=MeSH" title="MedGen record for Temporal Lobe Anaplastic Astrocytoma">Temporal Lobe Anaplastic Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1621925" ref="tree=MeSH" title="MedGen record for Recurrent Anaplastic Astrocytoma">Recurrent Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1709594" ref="tree=MeSH" title="MedGen record for Refractory Anaplastic Astrocytoma">Refractory Anaplastic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/231374" ref="tree=MeSH" title="MedGen record for Secondary Supratentorial Anaplastic Astrocytoma">Secondary Supratentorial Anaplastic Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/811330" ref="tree=MeSH" title="MedGen record for Brain astrocytoma">Brain astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/231458" ref="tree=MeSH" title="MedGen record for Brain stem astrocytic neoplasm">Brain stem astrocytic neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/234123" ref="tree=MeSH" title="MedGen record for Childhood brainstem astrocytoma">Childhood brainstem astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/196631" ref="tree=MeSH" title="MedGen record for Cerebellar astrocytoma">Cerebellar astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/91158" ref="tree=MeSH" title="MedGen record for Cerebellar pilocytic astrocytoma">Cerebellar pilocytic astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/124480" ref="tree=MeSH" title="MedGen record for Childhood cerebellar astrocytic neoplasm">Childhood cerebellar astrocytic neoplasm</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/196691" ref="tree=MeSH" title="MedGen record for Cerebral astrocytoma">Cerebral astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/137828" ref="tree=MeSH" title="MedGen record for Childhood cerebral astrocytoma">Childhood cerebral astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/232072" ref="tree=MeSH" title="MedGen record for Childhood optic tract astrocytoma">Childhood optic tract astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/235536" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Visual Pathway Astrocytoma">Recurrent Childhood Visual Pathway Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272542" ref="tree=MeSH" title="MedGen record for Diencephalic astrocytomas">Diencephalic astrocytomas</a></span></li><li><span class="TLline"><a href="/medgen/83711" ref="tree=MeSH" title="MedGen record for Pineal gland astrocytoma">Pineal gland astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1660183" ref="tree=MeSH" title="MedGen record for Supratentorial Pleomorphic Xanthoastrocytoma">Supratentorial Pleomorphic Xanthoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1663242" ref="tree=MeSH" title="MedGen record for Third Ventricle Pilocytic Astrocytoma">Third Ventricle Pilocytic Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235225" ref="tree=MeSH" title="MedGen record for Cauda equina intradural extramedullary astrocytoma">Cauda equina intradural extramedullary astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/272112" ref="tree=MeSH" title="MedGen record for Childhood astrocytic tumor">Childhood astrocytic tumor</a></span><ul><li><span class="TLline"><a href="/medgen/898003" ref="tree=MeSH" title="MedGen record for Childhood Astrocytoma">Childhood Astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/859262" ref="tree=MeSH" title="MedGen record for Childhood Diffuse Astrocytoma">Childhood Diffuse Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/232355" ref="tree=MeSH" title="MedGen record for Childhood pilocytic astrocytoma">Childhood pilocytic astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/859240" ref="tree=MeSH" title="MedGen record for Childhood Pilomyxoid Astrocytoma">Childhood Pilomyxoid Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/859239" ref="tree=MeSH" title="MedGen record for Childhood Pleomorphic Xanthoastrocytoma">Childhood Pleomorphic Xanthoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/853488" ref="tree=MeSH" title="MedGen record for Childhood Subependymal Giant Cell Astrocytoma">Childhood Subependymal Giant Cell Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/128836" ref="tree=MeSH" title="MedGen record for Childhood Glioblastoma">Childhood Glioblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/1639108" ref="tree=MeSH" title="MedGen record for Childhood Brain Glioblastoma">Childhood Brain Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/859253" ref="tree=MeSH" title="MedGen record for Childhood Giant Cell Glioblastoma">Childhood Giant Cell Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/859252" ref="tree=MeSH" title="MedGen record for Childhood Gliosarcoma">Childhood Gliosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/857346" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Glioblastoma">Recurrent Childhood Glioblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/857352" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Astrocytic Tumor">Recurrent Childhood Astrocytic Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/233909" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Brain Stem Astrocytoma">Recurrent Childhood Brain Stem Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/137885" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Cerebellar Astrocytoma">Recurrent Childhood Cerebellar Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/90912" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Cerebral Astrocytoma">Recurrent Childhood Cerebral Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/857350" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Diffuse Astrocytoma">Recurrent Childhood Diffuse Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/857340" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Pilocytic Astrocytoma">Recurrent Childhood Pilocytic Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/857339" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Pilomyxoid Astrocytoma">Recurrent Childhood Pilomyxoid Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/857338" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Pleomorphic Xanthoastrocytoma">Recurrent Childhood Pleomorphic Xanthoastrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/857336" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Subependymal Giant Cell Astrocytoma">Recurrent Childhood Subependymal Giant Cell Astrocytoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/42228" ref="tree=MeSH" title="MedGen record for Glioblastoma">Glioblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/83169" ref="tree=MeSH" title="MedGen record for Giant cell glioblastoma">Giant cell glioblastoma</a></span><ul><li><span class="TLline"><a href="/medgen/284232" ref="tree=MeSH" title="MedGen record for Adult Giant Cell Glioblastoma">Adult Giant Cell Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1680625" ref="tree=MeSH" title="MedGen record for Recurrent Giant Cell Glioblastoma">Recurrent Giant Cell Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1781610" ref="tree=MeSH" title="MedGen record for Refractory Giant Cell Glioblastoma">Refractory Giant Cell Glioblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/64638" ref="tree=MeSH" title="MedGen record for Gliosarcoma">Gliosarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/323796" ref="tree=MeSH" title="MedGen record for Adult Gliosarcoma">Adult Gliosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1390989" ref="tree=MeSH" title="MedGen record for Recurrent Gliosarcoma">Recurrent Gliosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1720516" ref="tree=MeSH" title="MedGen record for Refractory Gliosarcoma">Refractory Gliosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/1739476" ref="tree=MeSH" title="MedGen record for Supratentorial Gliosarcoma">Supratentorial Gliosarcoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/226850" ref="tree=MeSH" title="MedGen record for Gliofibroma">Gliofibroma</a></span></li><li><span class="TLline"><a href="/medgen/457397" ref="tree=MeSH" title="MedGen record for Glioneuronal Tumor with Neuropil-Like Islands">Glioneuronal Tumor with Neuropil-Like Islands</a></span></li><li><span class="TLline"><a href="/medgen/769639" ref="tree=MeSH" title="MedGen record for High grade astrocytic tumor">High grade astrocytic tumor</a></span><ul><li><span class="TLline"><a href="/medgen/458884" ref="tree=MeSH" title="MedGen record for Diffuse intrinsic pontine glioma">Diffuse intrinsic pontine glioma</a></span><ul><li><span class="TLline"><a href="/medgen/1624822" ref="tree=MeSH" title="MedGen record for Recurrent Diffuse Intrinsic Pontine Glioma">Recurrent Diffuse Intrinsic Pontine Glioma</a></span></li><li><span class="TLline"><a href="/medgen/1627149" ref="tree=MeSH" title="MedGen record for Refractory Diffuse Intrinsic Pontine Glioma">Refractory Diffuse Intrinsic Pontine Glioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/301585" ref="tree=MeSH" title="MedGen record for Glioblastoma multiforme">Glioblastoma multiforme</a></span><ul><li><span class="TLline"><a href="/medgen/1718223" ref="tree=MeSH" title="MedGen record for Astrocytoma, IDH-mutant, grade 4">Astrocytoma, IDH-mutant, grade 4</a></span></li><li><span class="TLline"><a href="/medgen/138100" ref="tree=MeSH" title="MedGen record for Brain glioblastoma">Brain glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/819942" ref="tree=MeSH" title="MedGen record for Glioblastoma by Gene Expression Profile">Glioblastoma by Gene Expression Profile</a></span></li><li><span class="TLline"><a href="/medgen/926566" ref="tree=MeSH" title="MedGen record for Glioblastoma with Primitive Neuronal Component">Glioblastoma with Primitive Neuronal Component</a></span></li><li><span class="TLline"><a href="/medgen/308044" ref="tree=MeSH" title="MedGen record for Glioblastoma, IDH-Wildtype">Glioblastoma, IDH-Wildtype</a></span></li><li><span class="TLline"><a href="/medgen/1762790" ref="tree=MeSH" title="MedGen record for Metastatic Glioblastoma">Metastatic Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1656515" ref="tree=MeSH" title="MedGen record for MGMT-Methylated Glioblastoma">MGMT-Methylated Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1392081" ref="tree=MeSH" title="MedGen record for MGMT-Unmethylated Glioblastoma">MGMT-Unmethylated Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/457396" ref="tree=MeSH" title="MedGen record for Multifocal Glioblastomas">Multifocal Glioblastomas</a></span></li><li><span class="TLline"><a href="/medgen/925837" ref="tree=MeSH" title="MedGen record for Recurrent Glioblastoma">Recurrent Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1645398" ref="tree=MeSH" title="MedGen record for Refractory Glioblastoma">Refractory Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1715986" ref="tree=MeSH" title="MedGen record for Resectable Glioblastoma">Resectable Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/311266" ref="tree=MeSH" title="MedGen record for Secondary Glioblastoma">Secondary Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/696081" ref="tree=MeSH" title="MedGen record for Small Cell Glioblastoma">Small Cell Glioblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1788246" ref="tree=MeSH" title="MedGen record for Unresectable Glioblastoma">Unresectable Glioblastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87267" ref="tree=MeSH" title="MedGen record for Gliomatosis cerebri">Gliomatosis cerebri</a></span><ul><li><span class="TLline"><a href="/medgen/856664" ref="tree=MeSH" title="MedGen record for Childhood Gliomatosis Cerebri">Childhood Gliomatosis Cerebri</a></span></li><li><span class="TLline"><a href="/medgen/274590" ref="tree=MeSH" title="MedGen record for Gliomatosis Cerebri Type I">Gliomatosis Cerebri Type I</a></span></li><li><span class="TLline"><a href="/medgen/268129" ref="tree=MeSH" title="MedGen record for Gliomatosis Cerebri Type II">Gliomatosis Cerebri Type II</a></span></li><li><span class="TLline"><a href="/medgen/1790936" ref="tree=MeSH" title="MedGen record for Recurrent Gliomatosis Cerebri">Recurrent Gliomatosis Cerebri</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/727259" ref="tree=MeSH" title="MedGen record for Low-grade astrocytoma">Low-grade astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/83708" ref="tree=MeSH" title="MedGen record for Diffuse astrocytoma">Diffuse astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/927224" ref="tree=MeSH" title="MedGen record for Astrocytoma, IDH-mutant, grade 2">Astrocytoma, IDH-mutant, grade 2</a></span></li><li><span class="TLline"><a href="/medgen/927223" ref="tree=MeSH" title="MedGen record for Diffuse Astrocytoma, IDH-Wildtype">Diffuse Astrocytoma, IDH-Wildtype</a></span></li><li><span class="TLline"><a href="/medgen/87270" ref="tree=MeSH" title="MedGen record for Fibrillary astrocytoma">Fibrillary astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/87269" ref="tree=MeSH" title="MedGen record for Gemistocytic astrocytoma">Gemistocytic astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/87268" ref="tree=MeSH" title="MedGen record for Protoplasmic astrocytoma">Protoplasmic astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1708891" ref="tree=MeSH" title="MedGen record for Recurrent Diffuse Astrocytoma">Recurrent Diffuse Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1791573" ref="tree=MeSH" title="MedGen record for Metastatic Low Grade Astrocytoma">Metastatic Low Grade Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/87271" ref="tree=MeSH" title="MedGen record for Pilocytic astrocytoma">Pilocytic astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/276757" ref="tree=MeSH" title="MedGen record for Pilomyxoid astrocytoma">Pilomyxoid astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1790685" ref="tree=MeSH" title="MedGen record for Recurrent Pilocytic Astrocytoma">Recurrent Pilocytic Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/458776" ref="tree=MeSH" title="MedGen record for Pituicytoma">Pituicytoma</a></span></li><li><span class="TLline"><a href="/medgen/137786" ref="tree=MeSH" title="MedGen record for Pleomorphic xanthoastrocytoma">Pleomorphic xanthoastrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/1650926" ref="tree=MeSH" title="MedGen record for Temporal Lobe Pleomorphic Xanthoastrocytoma">Temporal Lobe Pleomorphic Xanthoastrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1781955" ref="tree=MeSH" title="MedGen record for Recurrent Low Grade Astrocytoma">Recurrent Low Grade Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/1791071" ref="tree=MeSH" title="MedGen record for Refractory Low Grade Astrocytoma">Refractory Low Grade Astrocytoma</a></span></li><li><span class="TLline"><a href="/medgen/61446" ref="tree=MeSH" title="MedGen record for Subependymal giant-cell astrocytoma">Subependymal giant-cell astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/237052" ref="tree=MeSH" title="MedGen record for Optic tract astrocytoma">Optic tract astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/235405" ref="tree=MeSH" title="MedGen record for Optic nerve astrocytoma">Optic nerve astrocytoma</a></span><ul><li><span class="TLline"><a href="/medgen/277579" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Optic Nerve Astrocytoma">Recurrent Childhood Optic Nerve Astrocytoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/137924" ref="tree=MeSH" title="MedGen record for Retinal astrocytic hamartoma">Retinal astrocytic hamartoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/91152" ref="tree=MeSH" title="MedGen record for Spinal cord astrocytoma">Spinal cord astrocytoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=3754&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Astrocytoma</span> in Orphanet.</div></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_18013"><div><strong>Neurofibromatosis, type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>18013</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0027831</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
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<div class="spaceAbove">Neurofibromatosis 1 (NF1) is a multisystem disorder characterized by multiple café au lait macules, intertriginous freckling, multiple cutaneous neurofibromas, and learning disability or behavior problems. About half of people with NF1 have plexiform neurofibromas, but most are internal and not suspected clinically. Plexiform neurofibromas can cause pain, neurologic deficits, and abnormalities of involved or adjacent structures. Less common but potentially more serious manifestations include optic nerve and other central nervous system gliomas, malignant peripheral nerve sheath tumors, scoliosis, tibial dysplasia, vasculopathy, and gastrointestinal, endocrine, or pulmonary disease.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/18013">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_18014"><div><strong>Neurofibromatosis, type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>18014</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0027832</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
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<div class="spaceAbove">NF2-related schwannomatosis (NF2) is characterized by bilateral vestibular schwannomas with associated symptoms of tinnitus, hearing loss, and balance dysfunction. The average age of onset is 18 to 24 years. Almost all affected individuals develop bilateral vestibular schwannomas by age 30 years. Affected individuals may also develop schwannomas of other cranial and peripheral nerves, meningiomas, ependymomas, and (very rarely) low-grade astrocytomas. Because NF2 is considered an adult-onset disease, it may be underrecognized in children, in whom skin tumors and ocular findings (retinal hamartoma, thickened optic nerves, cortical wedge cataracts, third cranial nerve palsy) may be the first manifestations. Mononeuropathy that occurs in childhood is an increasingly recognized finding; it frequently presents as a persistent facial palsy or hand/foot drop.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/18014">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_140807"><div><strong>Encephalocraniocutaneous lipomatosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>140807</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0406612</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
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<div class="spaceAbove">Encephalocraniocutaneous lipomatosis (ECCL) comprises a spectrum of predominantly congenital anomalies. In its typical form, ECCL is characterized by congenital anomalies of the skin (nevus psiloliparus, patchy or streaky non-scarring alopecia, subcutaneous lipomas in the frontotemporal region, focal skin aplasia or hypoplasia on the scalp, and/or small nodular skin tags on the eyelids or between the outer canthus and tragus), eye (choristoma), and brain (in particular intracranial and spinal lipomas). To a much lesser degree, the bones and the heart can be affected. About 40% of affected individuals have bilateral abnormalities of the skin or the eyes. About one third of affected individuals have normal cognitive development, another one third have mild developmental delay (DD) or intellectual disability (ID), and the final one third have severe or unspecified DD/ID. Half of individuals have seizures. Affected individuals are at an increased (i.e., above the general population) risk of developing brain tumors, particularly low-grade gliomas such as pilocytic astrocytomas. There is evidence that oculoectodermal syndrome (OES) may constitute a clinical spectrum with ECCL, with OES on the mild end and ECCL on the more severe end of the spectrum.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/140807">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_331890"><div><strong>Melanoma and neural system tumor syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>331890</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1835042</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
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<div class="spaceAbove">The melanoma-astrocytoma syndrome is an autosomal dominant disorder characterized by a dual predisposition to melanoma and neural system tumors, commonly astrocytoma. In families with this disorder, patients with melanoma have a higher risk of developing neural system tumors, and this increased risk extends to both first and second degree relatives (summary by Randerson-Moor et al., 2001).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/331890">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_344288"><div><strong>Tuberous sclerosis 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>344288</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1854465</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Tuberous sclerosis complex (TSC) involves abnormalities of the skin (hypomelanotic macules, confetti skin lesions, facial angiofibromas, shagreen patches, fibrous cephalic plaques, ungual fibromas); brain (subependymal nodules, cortical tubers, and subependymal giant cell astrocytomas [SEGAs], seizures, TSC-associated neuropsychiatric disorder [TAND]); kidneys (benign renal angiomyolipomas, epithelial cysts, oncocytoma, renal cell carcinoma); heart (rhabdomyomas, arrhythmias); and lungs (lymphangioleiomyomatosis [LAM], multifocal micronodular pneumonocyte hyperplasia). Central nervous system-related problems (including TAND) are the leading cause of morbidity, whereas kidney disease is the leading cause of mortality.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/344288">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_348170"><div><strong>Tuberous sclerosis 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>348170</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1860707</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Tuberous sclerosis complex (TSC) involves abnormalities of the skin (hypomelanotic macules, confetti skin lesions, facial angiofibromas, shagreen patches, fibrous cephalic plaques, ungual fibromas); brain (subependymal nodules, cortical tubers, and subependymal giant cell astrocytomas [SEGAs], seizures, TSC-associated neuropsychiatric disorder [TAND]); kidneys (benign renal angiomyolipomas, epithelial cysts, oncocytoma, renal cell carcinoma); heart (rhabdomyomas, arrhythmias); and lungs (lymphangioleiomyomatosis [LAM], multifocal micronodular pneumonocyte hyperplasia). Central nervous system-related problems (including TAND) are the leading cause of morbidity, whereas kidney disease is the leading cause of mortality.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/348170">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_398651"><div><strong>Familial adenomatous polyposis 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>398651</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2713442</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">APC-associated polyposis conditions include (classic or attenuated) familial adenomatous polyposis (FAP) and gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS). FAP is a colorectal cancer (CRC) predisposition syndrome that can manifest in either classic or attenuated form. Classic FAP is characterized by hundreds to thousands of adenomatous colonic polyps, beginning on average at age 16 years (range 7-36 years). For those with the classic form of FAP, 95% of individuals have polyps by age 35 years; CRC is inevitable without colectomy. The mean age of CRC diagnosis in untreated individuals is 39 years (range 34-43 years). The attenuated form is characterized by multiple colonic polyps (average of 30), more proximally located polyps, and a diagnosis of CRC at a later age than in classic FAP. For those with an attenuated form, there is a 70% lifetime risk of CRC and the mean age of diagnosis is 50-55 years. Extracolonic manifestations are variably present and include polyps of the stomach and duodenum, osteomas, dental abnormalities, congenital hypertrophy of the retinal pigment epithelium (CHRPE), benign cutaneous lesions, desmoid tumors, adrenal masses, and other associated cancers. GAPPS is characterized by proximal gastric polyposis, increased risk of gastric adenocarcinoma, and no duodenal or colonic involvement in most individuals reported.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/398651">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_413414"><div><strong>Glioma susceptibility 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>413414</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2750850</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
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<div class="spaceAbove">Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas, ependymomas, and subependymomas. Glial cells can show various degrees of differentiation even within the same tumor (summary by Kyritsis et al., 2010). Ependymomas are rare glial tumors of the brain and spinal cord (Yokota et al., 2003). Subependymomas are unusual tumors believed to arise from the bipotential subependymal cell, which normally differentiates into either ependymal cells or astrocytes. They were characterized as a distinct entity by Scheinker (1945). They tend to be slow-growing, noninvasive, and located in the ventricular system, septum pellucidum, cerebral aqueduct, or proximal spinal cord (summary by Ryken et al., 1994). Gliomas are known to occur in association with several other well-defined hereditary tumor syndromes such as mismatch repair cancer syndrome (see 276300), melanoma-astrocytoma syndrome (155755), neurofibromatosis-1 (NF1; 162200) and neurofibromatosis-2 (see SWNV, 101000), and tuberous sclerosis (TSC1; 191100). Familial clustering of gliomas may occur in the absence of these tumor syndromes, however. Genetic Heterogeneity of Susceptibility to Glioma Other glioma susceptibilities include GLM2 (613028), caused by variation in the PTEN gene (601728) on chromosome 10q23; GLM3 (613029), caused by variation in the BRCA2 gene (600185) on chromosome 13q13; GLM4 (607248), mapped to chromosome 15q23-q26.3; GLM5 (613030), mapped to chromosome 9p21; GLM6 (613031), mapped to chromosome 20q13; GLM7 (613032), mapped to chromosome 8q24; GLM8 (613033), mapped to chromosome 5p15; and GLM9, caused by variation in the POT1 gene (606478) on chromosome 7q31. Somatic mutation, disruption, or copy number variation of the following genes or loci may also contribute to the formation of glioma: ERBB (EGFR; 131550), ERBB2 (164870), LGI1 (604619), GAS41 (602116), GLI (165220), DMBT1 (601969), IDH1 (147700), IDH2 (147650), BRAF (164757), PARK2 (602544), TP53 (191170), RB1 (614041), PIK3CA (171834), 10p15, 19q, and 17p13.3.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/413414">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_442777"><div><strong>Glioma susceptibility 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>442777</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2751641</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
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<div class="spaceAbove">Any malignant glioma in which the cause of the disease is a mutation in the BRCA2 gene.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/442777">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_934686"><div><strong>Familial adenomatous polyposis 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>934686</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4310719</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Familial adenomatous polyposis-4 is an autosomal recessive tumor predisposition syndrome characterized by the development of multiple colonic adenomas in adulthood, often with progression to colorectal cancer. Proliferative lesions in other tissues may also occur (summary by Adam et al., 2016). For a discussion of genetic heterogeneity of familial adenomatous polyposis, see FAP1 (175100).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/934686">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1748029"><div><strong>Mismatch repair cancer syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1748029</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5399763</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Lynch syndrome is characterized by an increased risk for colorectal cancer (CRC) and cancers of the endometrium, ovary, stomach, small bowel, urinary tract, biliary tract, brain (usually glioblastoma), skin (sebaceous adenomas, sebaceous carcinomas, and keratoacanthomas), pancreas, and prostate. Cancer risks and age of onset vary depending on the associated gene. Several other cancer types have been reported to occur in individuals with Lynch syndrome (e.g., breast, sarcomas, adrenocortical carcinoma). However, the data are not sufficient to demonstrate that the risk of developing these cancers is increased in individuals with Lynch syndrome.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1748029">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1733656"><div><strong>Mismatch repair cancer syndrome 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1733656</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436807</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Mismatch repair cancer syndrome-3 (MMRCS3) is an autosomal recessive childhood cancer predisposition syndrome characterized by brain tumors, hematologic malignancy, and gastrointestinal tumors. Multiple cafe-au-lait spots, axillary freckling, and, rarely, Lisch nodules reminiscent of neurofibromatosis type I (NF1; 162200) may be present (Hegde et al., 2005, Ostergaard et al., 2005). Microsatellite instability may be detected in tumor samples (Hegde et al., 2005). For a discussion of genetic heterogeneity of mismatch repair cancer syndrome, see MMRCS1 (276300).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1733656">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1745382"><div><strong>Mismatch repair cancer syndrome 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1745382</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436817</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Mismatch repair cancer syndrome-4 (MMRCS4) is an autosomal recessive childhood cancer predisposition syndrome characterized by early-onset leukemia/lymphoma, brain tumors, colorectal/gastrointestinal cancers, and other rare malignancies, including rhabdomyosarcoma (summary by Li et al., 2015). Cafe-au-lait spots are usually present (De Vos et al., 2006). For a discussion of genetic heterogeneity of mismatch repair cancer syndrome, see MMRCS1 (276300).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1745382">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1787559"><div><strong>Chordoma, susceptibility to</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1787559</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5441694</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1787559">Condition Record</a></div></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1787559" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Chordoma, susceptibility to</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_140807" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Encephalocraniocutaneous lipomatosis</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_398651" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial adenomatous polyposis 1</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_934686" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial adenomatous polyposis 4</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_413414" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glioma susceptibility 1</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (14)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_442777" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glioma susceptibility 3</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_331890" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Melanoma and neural system tumor syndrome</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1748029" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mismatch repair cancer syndrome 1</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1733656" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mismatch repair cancer syndrome 3</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1745382" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mismatch repair cancer syndrome 4</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_18013" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurofibromatosis, type 1</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_18014" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurofibromatosis, type 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_344288" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Tuberous sclerosis 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_348170" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Tuberous sclerosis 2</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35465885">Surgical Neuro-Oncology: Management of Glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mitchell D,
|
||
Shireman JM,
|
||
Dey M</span><br />
|
||
<span class="medgenPMjournal">Neurol Clin</span>
|
||
2022 May;40(2):437-453.
|
||
Epub 2022 Mar 31
|
||
doi: 10.1016/j.ncl.2021.11.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35465885" target="_blank">35465885</a><a href="/pmc/articles/PMC9048103" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30835699">Childhood brain tumors: current management, biological insights, and future directions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pollack IF,
|
||
Agnihotri S,
|
||
Broniscer A</span><br />
|
||
<span class="medgenPMjournal">J Neurosurg Pediatr</span>
|
||
2019 Mar 1;23(3):261-273.
|
||
doi: 10.3171/2018.10.PEDS18377.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30835699" target="_blank">30835699</a><a href="/pmc/articles/PMC6823600" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29455369">Intradural spinal tumors in adults-update on management and outcome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ottenhausen M,
|
||
Ntoulias G,
|
||
Bodhinayake I,
|
||
Ruppert FH,
|
||
Schreiber S,
|
||
Förschler A,
|
||
Boockvar JA,
|
||
Jödicke A</span><br />
|
||
<span class="medgenPMjournal">Neurosurg Rev</span>
|
||
2019 Jun;42(2):371-388.
|
||
Epub 2018 Feb 17
|
||
doi: 10.1007/s10143-018-0957-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29455369" target="_blank">29455369</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22astrocytoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (483)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/cns.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Central Nervous System Cancers, 2023</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33266110">Astrocytoma: A Hormone-Sensitive Tumor?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hirtz A,
|
||
Rech F,
|
||
Dubois-Pot-Schneider H,
|
||
Dumond H</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2020 Nov 30;21(23)
|
||
doi: 10.3390/ijms21239114.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33266110" target="_blank">33266110</a><a href="/pmc/articles/PMC7730176" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30916536">The management of low-grade gliomas in adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morshed RA,
|
||
Young JS,
|
||
Hervey-Jumper SL,
|
||
Berger MS</span><br />
|
||
<span class="medgenPMjournal">J Neurosurg Sci</span>
|
||
2019 Aug;63(4):450-457.
|
||
Epub 2019 Mar 27
|
||
doi: 10.23736/S0390-5616.19.04701-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30916536" target="_blank">30916536</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27511753">Peduncular psychosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Andrews JP,
|
||
Taylor J,
|
||
Saunders D,
|
||
Qayyum Z</span><br />
|
||
<span class="medgenPMjournal">BMJ Case Rep</span>
|
||
2016 Aug 10;2016
|
||
doi: 10.1136/bcr-2016-216165.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27511753" target="_blank">27511753</a><a href="/pmc/articles/PMC4986019" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12691624">Nonmalignant pediatric brain tumors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rashidi M,
|
||
DaSilva VR,
|
||
Minagar A,
|
||
Rutka JT</span><br />
|
||
<span class="medgenPMjournal">Curr Neurol Neurosci Rep</span>
|
||
2003 May;3(3):200-5.
|
||
doi: 10.1007/s11910-003-0079-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12691624" target="_blank">12691624</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10940774">Pathology of diencephalic astrocytomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Burger PC,
|
||
Cohen KJ,
|
||
Rosenblum MK,
|
||
Tihan T</span><br />
|
||
<span class="medgenPMjournal">Pediatr Neurosurg</span>
|
||
2000 Apr;32(4):214-9.
|
||
doi: 10.1159/000028937.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10940774" target="_blank">10940774</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Astrocytoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4931)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33266110">Astrocytoma: A Hormone-Sensitive Tumor?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hirtz A,
|
||
Rech F,
|
||
Dubois-Pot-Schneider H,
|
||
Dumond H</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2020 Nov 30;21(23)
|
||
doi: 10.3390/ijms21239114.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33266110" target="_blank">33266110</a><a href="/pmc/articles/PMC7730176" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32691644">Pilocytic Astrocytoma: A Review of General, Clinical, and Molecular Characteristics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Salles D,
|
||
Laviola G,
|
||
Malinverni ACM,
|
||
Stávale JN</span><br />
|
||
<span class="medgenPMjournal">J Child Neurol</span>
|
||
2020 Oct;35(12):852-858.
|
||
Epub 2020 Jul 20
|
||
doi: 10.1177/0883073820937225.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32691644" target="_blank">32691644</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24954244">Anaplastic pilocytic astrocytoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yong EX,
|
||
McKelvie P,
|
||
Murphy M,
|
||
Wang YY</span><br />
|
||
<span class="medgenPMjournal">J Clin Neurosci</span>
|
||
2014 Nov;21(11):1993-6.
|
||
Epub 2014 Jun 19
|
||
doi: 10.1016/j.jocn.2014.02.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24954244" target="_blank">24954244</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12241877">Goosebumps.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cutts J,
|
||
Lee G,
|
||
Berarducci M,
|
||
Thomas C,
|
||
Dempsey PK,
|
||
Kadish SP</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2002 Aug 31;360(9334):690.
|
||
doi: 10.1016/s0140-6736(02)09840-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12241877" target="_blank">12241877</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/14227701">SPONTANEOUS VENTRICULOSTOMY.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">LESLIE EV,
|
||
ALKER GJ Jr</span><br />
|
||
<span class="medgenPMjournal">Radiology</span>
|
||
1964 Oct;83:683-6.
|
||
doi: 10.1148/83.4.683.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14227701" target="_blank">14227701</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Astrocytoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6991)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35130560">GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Majzner RG,
|
||
Ramakrishna S,
|
||
Yeom KW,
|
||
Patel S,
|
||
Chinnasamy H,
|
||
Schultz LM,
|
||
Richards RM,
|
||
Jiang L,
|
||
Barsan V,
|
||
Mancusi R,
|
||
Geraghty AC,
|
||
Good Z,
|
||
Mochizuki AY,
|
||
Gillespie SM,
|
||
Toland AMS,
|
||
Mahdi J,
|
||
Reschke A,
|
||
Nie EH,
|
||
Chau IJ,
|
||
Rotiroti MC,
|
||
Mount CW,
|
||
Baggott C,
|
||
Mavroukakis S,
|
||
Egeler E,
|
||
Moon J,
|
||
Erickson C,
|
||
Green S,
|
||
Kunicki M,
|
||
Fujimoto M,
|
||
Ehlinger Z,
|
||
Reynolds W,
|
||
Kurra S,
|
||
Warren KE,
|
||
Prabhu S,
|
||
Vogel H,
|
||
Rasmussen L,
|
||
Cornell TT,
|
||
Partap S,
|
||
Fisher PG,
|
||
Campen CJ,
|
||
Filbin MG,
|
||
Grant G,
|
||
Sahaf B,
|
||
Davis KL,
|
||
Feldman SA,
|
||
Mackall CL,
|
||
Monje M</span><br />
|
||
<span class="medgenPMjournal">Nature</span>
|
||
2022 Mar;603(7903):934-941.
|
||
Epub 2022 Feb 7
|
||
doi: 10.1038/s41586-022-04489-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35130560" target="_blank">35130560</a><a href="/pmc/articles/PMC8967714" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34898238">Therapy for Diffuse Astrocytic and Oligodendroglial Tumors in Adults: ASCO-SNO Guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mohile NA,
|
||
Messersmith H,
|
||
Gatson NT,
|
||
Hottinger AF,
|
||
Lassman A,
|
||
Morton J,
|
||
Ney D,
|
||
Nghiemphu PL,
|
||
Olar A,
|
||
Olson J,
|
||
Perry J,
|
||
Portnow J,
|
||
Schiff D,
|
||
Shannon A,
|
||
Shih HA,
|
||
Strowd R,
|
||
van den Bent M,
|
||
Ziu M,
|
||
Blakeley J</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2022 Feb 1;40(4):403-426.
|
||
Epub 2021 Dec 13
|
||
doi: 10.1200/JCO.21.02036.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34898238" target="_blank">34898238</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32164789">Pediatric low-grade glioma in the era of molecular diagnostics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ryall S,
|
||
Tabori U,
|
||
Hawkins C</span><br />
|
||
<span class="medgenPMjournal">Acta Neuropathol Commun</span>
|
||
2020 Mar 12;8(1):30.
|
||
doi: 10.1186/s40478-020-00902-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32164789" target="_blank">32164789</a><a href="/pmc/articles/PMC7066826" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27230974">Anaplastic astrocytoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grimm SA,
|
||
Chamberlain MC</span><br />
|
||
<span class="medgenPMjournal">CNS Oncol</span>
|
||
2016 Jul;5(3):145-57.
|
||
Epub 2016 May 27
|
||
doi: 10.2217/cns-2016-0002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27230974" target="_blank">27230974</a><a href="/pmc/articles/PMC6042632" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27050206">Radiation plus Procarbazine, CCNU, and Vincristine in Low-Grade Glioma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Buckner JC,
|
||
Shaw EG,
|
||
Pugh SL,
|
||
Chakravarti A,
|
||
Gilbert MR,
|
||
Barger GR,
|
||
Coons S,
|
||
Ricci P,
|
||
Bullard D,
|
||
Brown PD,
|
||
Stelzer K,
|
||
Brachman D,
|
||
Suh JH,
|
||
Schultz CJ,
|
||
Bahary JP,
|
||
Fisher BJ,
|
||
Kim H,
|
||
Murtha AD,
|
||
Bell EH,
|
||
Won M,
|
||
Mehta MP,
|
||
Curran WJ Jr</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2016 Apr 7;374(14):1344-55.
|
||
doi: 10.1056/NEJMoa1500925.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27050206" target="_blank">27050206</a><a href="/pmc/articles/PMC5170873" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Astrocytoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2977)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36382478">Incidence and morphology of secondary TDP-43 proteinopathies: Part 1.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Acewicz A,
|
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Stępień T,
|
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Felczak P,
|
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Tarka S,
|
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Wierzba-Bobrowicz T</span><br />
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<span class="medgenPMjournal">Folia Neuropathol</span>
|
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2022;60(3):267-276.
|
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doi: 10.5114/fn.2022.120314.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36382478" target="_blank">36382478</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15117797">The logrank test.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bland JM,
|
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Altman DG</span><br />
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<span class="medgenPMjournal">BMJ</span>
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2004 May 1;328(7447):1073.
|
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doi: 10.1136/bmj.328.7447.1073.
|
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<span class="bold">PMID: </span><a href="/pubmed/15117797" target="_blank">15117797</a><a href="/pmc/articles/PMC403858" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11701246">Neuropathology of tuberous sclerosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mizuguchi M,
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Takashima S</span><br />
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<span class="medgenPMjournal">Brain Dev</span>
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2001 Nov;23(7):508-15.
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doi: 10.1016/s0387-7604(01)00304-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11701246" target="_blank">11701246</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8584002">High-grade astrocytomas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wen PY,
|
||
Fine HA,
|
||
Black PM,
|
||
Shrieve DC,
|
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Alexander E 3rd,
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Loeffler JS</span><br />
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<span class="medgenPMjournal">Neurol Clin</span>
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1995 Nov;13(4):875-900.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8584002" target="_blank">8584002</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4016701">Cerebral pilocytic astrocytoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Clark GB,
|
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Henry JM,
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McKeever PE</span><br />
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<span class="medgenPMjournal">Cancer</span>
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1985 Sep 1;56(5):1128-33.
|
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doi: 10.1002/1097-0142(19850901)56:5<1128::aid-cncr2820560529>3.0.co;2-j.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4016701" target="_blank">4016701</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Astrocytoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5240)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38713025">MRI Scoring Systems for Predicting Isocitrate Dehydrogenase Mutation and Chromosome 1p/19q Codeletion in Adult-type Diffuse Glioma Lacking Contrast Enhancement.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kang KM,
|
||
Song J,
|
||
Choi Y,
|
||
Park C,
|
||
Park JE,
|
||
Kim HS,
|
||
Park SH,
|
||
Park CK,
|
||
Choi SH</span><br />
|
||
<span class="medgenPMjournal">Radiology</span>
|
||
2024 May;311(2):e233120.
|
||
doi: 10.1148/radiol.233120.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38713025" target="_blank">38713025</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34898238">Therapy for Diffuse Astrocytic and Oligodendroglial Tumors in Adults: ASCO-SNO Guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mohile NA,
|
||
Messersmith H,
|
||
Gatson NT,
|
||
Hottinger AF,
|
||
Lassman A,
|
||
Morton J,
|
||
Ney D,
|
||
Nghiemphu PL,
|
||
Olar A,
|
||
Olson J,
|
||
Perry J,
|
||
Portnow J,
|
||
Schiff D,
|
||
Shannon A,
|
||
Shih HA,
|
||
Strowd R,
|
||
van den Bent M,
|
||
Ziu M,
|
||
Blakeley J</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2022 Feb 1;40(4):403-426.
|
||
Epub 2021 Dec 13
|
||
doi: 10.1200/JCO.21.02036.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34898238" target="_blank">34898238</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27936528">Infratentorial ganglioglioma mimicking pilocytic astrocytoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta K,
|
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Karthigeyan M,
|
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Salunke P</span><br />
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<span class="medgenPMjournal">Clin Neuropathol</span>
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2017 Mar/Apr;36 (2017)(2):78-82.
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doi: 10.5414/NP300974.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27936528" target="_blank">27936528</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21343878">Grading of gliomas: the road from eminence to evidence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kros JM</span><br />
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<span class="medgenPMjournal">J Neuropathol Exp Neurol</span>
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2011 Feb;70(2):101-9.
|
||
doi: 10.1097/NEN.0b013e31820681aa.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21343878" target="_blank">21343878</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2403835">Malignant transformation of benign cerebellar astrocytoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schwartz AM,
|
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Ghatak NR</span><br />
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<span class="medgenPMjournal">Cancer</span>
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1990 Jan 15;65(2):333-6.
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doi: 10.1002/1097-0142(19900115)65:2<333::aid-cncr2820650225>3.0.co;2-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2403835" target="_blank">2403835</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Astrocytoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4230)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37903471">Middle Meningeal Artery Embolization in Pediatric Patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vazquez S,
|
||
Zuckerman DA,
|
||
Gandhi C,
|
||
Al-Mufti F,
|
||
Muh C,
|
||
Santarelli J,
|
||
Pisapia JM</span><br />
|
||
<span class="medgenPMjournal">Pediatr Neurosurg</span>
|
||
2024;59(1):44-53.
|
||
Epub 2023 Oct 30
|
||
doi: 10.1159/000534895.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37903471" target="_blank">37903471</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37451363">Supratotal Resection: An Emerging Concept of Glioblastoma Multiforme Surgery-Systematic Review And Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aziz PA,
|
||
Memon SF,
|
||
Hussain M,
|
||
Memon AR,
|
||
Abbas K,
|
||
Qazi SU,
|
||
Memon RAR,
|
||
Qambrani KA,
|
||
Taj O,
|
||
Ghazanfar S,
|
||
Ellahi A,
|
||
Ahmed M</span><br />
|
||
<span class="medgenPMjournal">World Neurosurg</span>
|
||
2023 Nov;179:e46-e55.
|
||
Epub 2023 Jul 13
|
||
doi: 10.1016/j.wneu.2023.07.020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37451363" target="_blank">37451363</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34898238">Therapy for Diffuse Astrocytic and Oligodendroglial Tumors in Adults: ASCO-SNO Guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mohile NA,
|
||
Messersmith H,
|
||
Gatson NT,
|
||
Hottinger AF,
|
||
Lassman A,
|
||
Morton J,
|
||
Ney D,
|
||
Nghiemphu PL,
|
||
Olar A,
|
||
Olson J,
|
||
Perry J,
|
||
Portnow J,
|
||
Schiff D,
|
||
Shannon A,
|
||
Shih HA,
|
||
Strowd R,
|
||
van den Bent M,
|
||
Ziu M,
|
||
Blakeley J</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2022 Feb 1;40(4):403-426.
|
||
Epub 2021 Dec 13
|
||
doi: 10.1200/JCO.21.02036.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34898238" target="_blank">34898238</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32918116">Hydrocephalus in primary intradural spinal cord tumors: a systematic review of the literature in the pediatric population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lampros M,
|
||
Voulgaris S,
|
||
Alexiou GA</span><br />
|
||
<span class="medgenPMjournal">Neurosurg Rev</span>
|
||
2021 Aug;44(4):2079-2084.
|
||
Epub 2020 Sep 11
|
||
doi: 10.1007/s10143-020-01386-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32918116" target="_blank">32918116</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32421989">Epstein-Barr Virus and Astrocytoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Freixo C,
|
||
Hermouet S,
|
||
Neves AM</span><br />
|
||
<span class="medgenPMjournal">Crit Rev Oncog</span>
|
||
2019;24(4):339-347.
|
||
doi: 10.1615/CritRevOncog.2020032954.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32421989" target="_blank">32421989</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Astrocytoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (99)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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|
||
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|
||
|
||
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|
||
|
||
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|
||
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|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
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|
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|
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|
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0004114%5bDISCUI%5d&filter=method%3A2%5F15" target="_blank">Methylation analysis (3)</a></li>
|
||
<li><a href="/gtr/tests?term=C0004114%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (3)</a></li>
|
||
<li><a href="/gtr/tests?term=C0004114%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (1)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0004114%5bDISCUI%5d" target="_blank">See all (7)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Astrocytoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22astrocytoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Astrocytoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/cns.pdf">NCCN, 2023</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Central Nervous System Cancers, 2023</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.malacards.org/card/glioma_susceptibility_1" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Astrocytoma" target="_blank">MedlinePlus</a></li></ul></div>
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