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<meta name="keywords" content="C1285162, degenerative disease, degenerative disorder, disease or syndrome, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A disorder characterized by the progressive loss of function and/or structure of the affected tissues." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=224837
ConceptID=C1285162
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Degenerative disorder</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>224837</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1285162</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Degenerative Disease; Degenerative Disorder</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Degenerative disorder (362975008)</td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A disorder characterized by the progressive loss of function and/or structure of the affected tissues. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
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<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Degenerative disorder</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/311052" ref="tree=MeSH" title="MedGen record for Non-Neoplastic Disorder">Non-Neoplastic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/317955" ref="tree=MeSH" title="MedGen record for Non-Neoplastic Disorder by Special Category">Non-Neoplastic Disorder by Special Category</a></span><ul><li><span class="matched_ds">Degenerative disorder</span><ul><li><span class="TLline"><a href="/medgen/124363" ref="tree=MeSH" title="MedGen record for Degenerative disease of the central nervous system">Degenerative disease of the central nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/274" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis">Amyotrophic lateral sclerosis</a></span><ul><li><span class="TLline"><a href="/medgen/462753" ref="tree=MeSH" title="MedGen record for Amyotrophic Lateral Sclerosis 14, With or Without Frontotemporal Dementia">Amyotrophic Lateral Sclerosis 14, With or Without Frontotemporal Dementia</a></span></li><li><span class="TLline"><a href="/medgen/400169" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 1">Amyotrophic lateral sclerosis type 1</a></span></li><li><span class="TLline"><a href="/medgen/339829" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 3">Amyotrophic lateral sclerosis type 3</a></span></li><li><span class="TLline"><a href="/medgen/355983" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 4">Amyotrophic lateral sclerosis type 4</a></span></li><li><span class="TLline"><a href="/medgen/419901" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 6">Amyotrophic lateral sclerosis type 6</a></span></li><li><span class="TLline"><a href="/medgen/334136" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 7">Amyotrophic lateral sclerosis type 7</a></span></li><li><span class="TLline"><a href="/medgen/325237" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 8">Amyotrophic lateral sclerosis type 8</a></span></li><li><span class="TLline"><a href="/medgen/395629" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 9">Amyotrophic lateral sclerosis type 9</a></span></li><li><span class="TLline"><a href="/medgen/383137" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 10">Amyotrophic lateral sclerosis type 10</a></span></li><li><span class="TLline"><a href="/medgen/393399" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 11">Amyotrophic lateral sclerosis type 11</a></span></li><li><span class="TLline"><a href="/medgen/813851" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 21">Amyotrophic lateral sclerosis type 21</a></span></li><li><span class="TLline"><a href="/medgen/1645924" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 23">Amyotrophic lateral sclerosis type 23</a></span></li><li><span class="TLline"><a href="/medgen/923704" ref="tree=MeSH" title="MedGen record for Juvenile amyotrophic lateral sclerosis">Juvenile amyotrophic lateral sclerosis</a></span></li><li><span class="TLline"><a href="/medgen/214634" ref="tree=MeSH" title="MedGen record for Progressive muscular atrophy">Progressive muscular atrophy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1617621" ref="tree=MeSH" title="MedGen record for Brachial amyotrophic diplegia">Brachial amyotrophic diplegia</a></span></li><li><span class="TLline"><a href="/medgen/854" ref="tree=MeSH" title="MedGen record for Cerebral palsy">Cerebral palsy</a></span><ul><li><span class="TLline"><a href="/medgen/95998" ref="tree=MeSH" title="MedGen record for Ataxic cerebral palsy">Ataxic cerebral palsy</a></span></li><li><span class="TLline"><a href="/medgen/82853" ref="tree=MeSH" title="MedGen record for Athetoid cerebral palsy">Athetoid cerebral palsy</a></span></li><li><span class="TLline"><a href="/medgen/98296" ref="tree=MeSH" title="MedGen record for Hypotonic cerebral palsy">Hypotonic cerebral palsy</a></span></li><li><span class="TLline"><a 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paraplegia 3A">Hereditary spastic paraplegia 3A</a></span></li><li><span class="TLline"><a href="/medgen/481368" ref="tree=MeSH" title="MedGen record for Hereditary spastic paraplegia 47">Hereditary spastic paraplegia 47</a></span></li><li><span class="TLline"><a href="/medgen/376521" ref="tree=MeSH" title="MedGen record for Hereditary spastic paraplegia 5A">Hereditary spastic paraplegia 5A</a></span></li><li><span class="TLline"><a href="/medgen/777979" ref="tree=MeSH" title="MedGen record for Spastic Paraplegia 4">Spastic Paraplegia 4</a></span></li><li><span class="TLline"><a href="/medgen/1678550" ref="tree=MeSH" title="MedGen record for Spastic Paraplegia 76">Spastic Paraplegia 76</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/61440" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease">Pelizaeus-Merzbacher disease</a></span><ul><li><span class="TLline"><a href="/medgen/1740046" ref="tree=MeSH" title="MedGen record for Null syndrome">Null syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1753109" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease in female carriers">Pelizaeus-Merzbacher disease in female carriers</a></span></li><li><span class="TLline"><a href="/medgen/155959" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease, classic form">Pelizaeus-Merzbacher disease, classic form</a></span></li><li><span class="TLline"><a href="/medgen/1842817" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease, connatal form">Pelizaeus-Merzbacher disease, connatal form</a></span></li><li><span class="TLline"><a href="/medgen/199764" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease, transitional form">Pelizaeus-Merzbacher disease, transitional form</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/116020" ref="tree=MeSH" title="MedGen record for Pick disease">Pick disease</a></span></li><li><span class="TLline"><a href="/medgen/6708" ref="tree=MeSH" title="MedGen record for Pigmentary pallidal degeneration">Pigmentary pallidal degeneration</a></span><ul><li><span class="TLline"><a href="/medgen/1800044" ref="tree=MeSH" title="MedGen record for Atypical pantothenate kinase-associated neurodegeneration">Atypical pantothenate kinase-associated neurodegeneration</a></span></li><li><span class="TLline"><a href="/medgen/1826057" ref="tree=MeSH" title="MedGen record for Classic pantothenate kinase-associated neurodegeneration">Classic pantothenate kinase-associated neurodegeneration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/21026" ref="tree=MeSH" title="MedGen record for Progressive supranuclear palsy">Progressive supranuclear palsy</a></span><ul><li><span class="TLline"><a href="/medgen/1779597" ref="tree=MeSH" title="MedGen record for Atypical progressive supranuclear palsy syndrome">Atypical progressive supranuclear palsy syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1640811" ref="tree=MeSH" title="MedGen record for Supranuclear palsy, progressive, 1">Supranuclear palsy, progressive, 1</a></span></li><li><span class="TLline"><a href="/medgen/324446" ref="tree=MeSH" title="MedGen record for Supranuclear palsy, progressive, 2">Supranuclear palsy, progressive, 2</a></span></li><li><span class="TLline"><a href="/medgen/370922" ref="tree=MeSH" title="MedGen record for Supranuclear palsy, progressive, 3">Supranuclear palsy, progressive, 3</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/39733" ref="tree=MeSH" title="MedGen record for Spinocerebellar atrophy">Spinocerebellar atrophy</a></span><ul><li><span class="TLline"><a href="/medgen/767604" ref="tree=MeSH" title="MedGen record for Ataxia with oculomotor apraxia type 3">Ataxia with oculomotor apraxia type 3</a></span></li><li><span class="TLline"><a href="/medgen/395301" ref="tree=MeSH" title="MedGen record for Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia">Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia</a></span></li><li><span class="TLline"><a href="/medgen/439" ref="tree=MeSH" title="MedGen record for Ataxia-telangiectasia syndrome">Ataxia-telangiectasia syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1684639" ref="tree=MeSH" title="MedGen record for Autosomal dominant cerebellar ataxia">Autosomal dominant cerebellar ataxia</a></span></li><li><span class="TLline"><a href="/medgen/1843058" ref="tree=MeSH" title="MedGen record for Autosomal recessive cerebellar ataxia">Autosomal recessive cerebellar ataxia</a></span></li><li><span class="TLline"><a href="/medgen/9841" ref="tree=MeSH" title="MedGen record for Azorean disease">Azorean disease</a></span></li><li><span class="TLline"><a href="/medgen/341248" ref="tree=MeSH" title="MedGen record for Familial isolated deficiency of vitamin E">Familial isolated deficiency of vitamin E</a></span></li><li><span class="TLline"><a href="/medgen/156006" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia 7">Spinocerebellar ataxia 7</a></span></li><li><span class="TLline"><a href="/medgen/155703" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 1">Spinocerebellar ataxia type 1</a></span></li><li><span class="TLline"><a href="/medgen/155704" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 2">Spinocerebellar ataxia type 2</a></span></li><li><span class="TLline"><a href="/medgen/148458" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 6">Spinocerebellar ataxia type 6</a></span></li><li><span class="TLline"><a href="/medgen/347653" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 12">Spinocerebellar ataxia type 12</a></span></li><li><span class="TLline"><a href="/medgen/337637" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 17">Spinocerebellar ataxia type 17</a></span></li><li><span class="TLline"><a href="/medgen/1711119" ref="tree=MeSH" title="MedGen record for Spinocerebellar Ataxia Type 19/22">Spinocerebellar Ataxia Type 19/22</a></span></li><li><span class="TLline"><a href="/medgen/348439" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 31">Spinocerebellar ataxia type 31</a></span></li><li><span class="TLline"><a href="/medgen/483339" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 36">Spinocerebellar ataxia type 36</a></span></li><li><span class="TLline"><a href="/medgen/902592" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 42">Spinocerebellar ataxia type 42</a></span></li><li><span class="TLline"><a href="/medgen/340052" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2">Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124366" ref="tree=MeSH" title="MedGen record for Striatonigral degeneration">Striatonigral degeneration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/4189" ref="tree=MeSH" title="MedGen record for Demyelinating disease">Demyelinating disease</a></span><ul><li><span class="TLline"><a href="/medgen/64511" ref="tree=MeSH" title="MedGen record for Central pontine myelinolysis">Central pontine myelinolysis</a></span></li><li><span class="TLline"><a href="/medgen/199756" ref="tree=MeSH" title="MedGen record for CNS demyelinating autoimmune disease">CNS demyelinating autoimmune disease</a></span><ul><li><span class="TLline"><a href="/medgen/4033" ref="tree=MeSH" title="MedGen record for Acute disseminated encephalomyelitis">Acute disseminated encephalomyelitis</a></span></li><li><span class="TLline"><a href="/medgen/4937" ref="tree=MeSH" title="MedGen record for Acute hemorrhagic leukoencephalitis">Acute hemorrhagic leukoencephalitis</a></span></li><li><span class="TLline"><a href="/medgen/10123" ref="tree=MeSH" title="MedGen record for Multiple sclerosis">Multiple sclerosis</a></span></li><li><span class="TLline"><a href="/medgen/45063" ref="tree=MeSH" title="MedGen record for Neuromyelitis optica">Neuromyelitis optica</a></span></li><li><span class="TLline"><a href="/medgen/3324" ref="tree=MeSH" title="MedGen record for Schilder disease">Schilder disease</a></span></li><li><span class="TLline"><a href="/medgen/6488" ref="tree=MeSH" title="MedGen record for Transverse myelitis">Transverse myelitis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/82859" ref="tree=MeSH" title="MedGen record for Demyelinating peripheral neuropathy">Demyelinating peripheral neuropathy</a></span><ul><li><span class="TLline"><a href="/medgen/870486" ref="tree=MeSH" title="MedGen record for Acute demyelinating polyneuropathy">Acute demyelinating polyneuropathy</a></span></li><li><span class="TLline"><a href="/medgen/98292" ref="tree=MeSH" title="MedGen record for Chronic inflammatory demyelinating polyradiculoneuropathy">Chronic inflammatory demyelinating polyradiculoneuropathy</a></span></li><li><span class="TLline"><a href="/medgen/868959" ref="tree=MeSH" title="MedGen record for Demyelinating sensory neuropathy">Demyelinating sensory neuropathy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/148407" ref="tree=MeSH" title="MedGen record for Hereditary Central Nervous System Demyelinating Diseases">Hereditary Central Nervous System Demyelinating Diseases</a></span><ul><li><span class="TLline"><a href="/medgen/57667" ref="tree=MeSH" title="MedGen record for Adrenoleukodystrophy">Adrenoleukodystrophy</a></span></li><li><span class="TLline"><a href="/medgen/78724" ref="tree=MeSH" title="MedGen record for Alexander disease">Alexander disease</a></span></li><li><span class="TLline"><a href="/medgen/44131" ref="tree=MeSH" title="MedGen record for Galactosylceramide beta-galactosidase deficiency">Galactosylceramide beta-galactosidase deficiency</a></span></li><li><span class="TLline"><a href="/medgen/6071" ref="tree=MeSH" title="MedGen record for Metachromatic leukodystrophy">Metachromatic leukodystrophy</a></span></li><li><span class="TLline"><a href="/medgen/61565" ref="tree=MeSH" title="MedGen record for Spongy degeneration of central nervous system">Spongy degeneration of central nervous system</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/65955" ref="tree=MeSH" title="MedGen record for Marchiafava-Bignami disease">Marchiafava-Bignami disease</a></span></li><li><span class="TLline"><a href="/medgen/46012" ref="tree=MeSH" title="MedGen record for Polyradiculoneuropathy">Polyradiculoneuropathy</a></span><ul><li><span class="TLline"><a href="/medgen/98229" ref="tree=MeSH" title="MedGen record for Cauda equina syndrome">Cauda equina syndrome</a></span></li><li><span class="TLline"><a href="/medgen/5399" ref="tree=MeSH" title="MedGen record for Guillain-Barre syndrome">Guillain-Barre syndrome</a></span></li><li><span class="TLline"><a href="/medgen/46011" ref="tree=MeSH" title="MedGen record for Polyradiculopathy">Polyradiculopathy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/7327" ref="tree=MeSH" title="MedGen record for Progressive multifocal leukoencephalopathy">Progressive multifocal leukoencephalopathy</a></span></li><li><span class="TLline"><a href="/medgen/452212" ref="tree=MeSH" title="MedGen record for Recurrent painful ophthalmoplegic neuropathy">Recurrent painful ophthalmoplegic neuropathy</a></span></li><li><span class="TLline"><a href="/medgen/113144" ref="tree=MeSH" title="MedGen record for Subacute combined degeneration of spinal cord">Subacute combined degeneration of spinal cord</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233865" ref="tree=MeSH" title="MedGen record for Plexopathy">Plexopathy</a></span><ul><li><span class="TLline"><a href="/medgen/148580" ref="tree=MeSH" title="MedGen record for Brachial plexus neuropathy">Brachial plexus neuropathy</a></span><ul><li><span class="TLline"><a href="/medgen/113170" ref="tree=MeSH" title="MedGen record for Brachial plexus neuritis">Brachial plexus neuritis</a></span></li><li><span class="TLline"><a href="/medgen/1640851" ref="tree=MeSH" title="MedGen record for Neonatal Brachial Plexus Palsy">Neonatal Brachial Plexus Palsy</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/236838" ref="tree=MeSH" title="MedGen record for Spinal Degenerative Disorder">Spinal Degenerative Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/102357" ref="tree=MeSH" title="MedGen record for Intervertebral disk degeneration">Intervertebral disk degeneration</a></span><ul><li><span class="TLline"><a href="/medgen/96081" ref="tree=MeSH" title="MedGen record for Cervical disk degenerative disorder">Cervical disk degenerative disorder</a></span></li><li><span class="TLline"><a href="/medgen/75530" ref="tree=MeSH" title="MedGen record for Degeneration of lumbar intervertebral disc">Degeneration of lumbar intervertebral disc</a></span></li><li><span class="TLline"><a href="/medgen/120491" ref="tree=MeSH" title="MedGen record for Thoracic disk degenerative disorder">Thoracic disk degenerative disorder</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/120488" ref="tree=MeSH" title="MedGen record for Spinal arthritis deformans">Spinal arthritis deformans</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/36708320">Omaveloxolone: an activator of Nrf2 for the treatment of Friedreich ataxia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Profeta V,
McIntyre K,
Wells M,
Park C,
Lynch DR</span><br />
<span class="medgenPMjournal">Expert Opin Investig Drugs</span>
2023 Jan;32(1):5-16.
Epub 2023 Feb 8
doi: 10.1080/13543784.2023.2173063.
<span class="bold">PMID: </span><a href="/pubmed/36708320" target="_blank">36708320</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27855131">Patellar Tendinopathy: Diagnosis and Treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Figueroa D,
Figueroa F,
Calvo R</span><br />
<span class="medgenPMjournal">J Am Acad Orthop Surg</span>
2016 Dec;24(12):e184-e192.
doi: 10.5435/JAAOS-D-15-00703.
<span class="bold">PMID: </span><a href="/pubmed/27855131" target="_blank">27855131</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22230308">Osteoarthritis: diagnosis and treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sinusas K</span><br />
<span class="medgenPMjournal">Am Fam Physician</span>
2012 Jan 1;85(1):49-56.
<span class="bold">PMID: </span><a href="/pubmed/22230308" target="_blank">22230308</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22degenerative%20disorder%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (41)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/36980302">Biomarkers Assessing Endothelial Dysfunction in Alzheimer's Disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Custodia A,
Aramburu-Núñez M,
Rodríguez-Arrizabalaga M,
Pías-Peleteiro JM,
Vázquez-Vázquez L,
Camino-Castiñeiras J,
Aldrey JM,
Castillo J,
Ouro A,
Sobrino T,
Romaus-Sanjurjo D</span><br />
<span class="medgenPMjournal">Cells</span>
2023 Mar 22;12(6)
doi: 10.3390/cells12060962.
<span class="bold">PMID: </span><a href="/pubmed/36980302" target="_blank">36980302</a><a href="/pmc/articles/PMC10047803" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27855131">Patellar Tendinopathy: Diagnosis and Treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Figueroa D,
Figueroa F,
Calvo R</span><br />
<span class="medgenPMjournal">J Am Acad Orthop Surg</span>
2016 Dec;24(12):e184-e192.
doi: 10.5435/JAAOS-D-15-00703.
<span class="bold">PMID: </span><a href="/pubmed/27855131" target="_blank">27855131</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22230308">Osteoarthritis: diagnosis and treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sinusas K</span><br />
<span class="medgenPMjournal">Am Fam Physician</span>
2012 Jan 1;85(1):49-56.
<span class="bold">PMID: </span><a href="/pubmed/22230308" target="_blank">22230308</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12897215">Osteoarthritis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Haq I,
Murphy E,
Dacre J</span><br />
<span class="medgenPMjournal">Postgrad Med J</span>
2003 Jul;79(933):377-83.
doi: 10.1136/pmj.79.933.377.
<span class="bold">PMID: </span><a href="/pubmed/12897215" target="_blank">12897215</a><a href="/pmc/articles/PMC1742743" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9061754">Huntington's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Craufurd D</span><br />
<span class="medgenPMjournal">Prenat Diagn</span>
1996 Dec;16(13):1237-45.
doi: 10.1002/(SICI)1097-0223(199612)16:13&lt;1237::AID-PD98&gt;3.0.CO;2-T.
<span class="bold">PMID: </span><a href="/pubmed/9061754" target="_blank">9061754</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disorder%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (210)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/28320194">Acquired pendular nystagmus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kang S,
Shaikh AG</span><br />
<span class="medgenPMjournal">J Neurol Sci</span>
2017 Apr 15;375:8-17.
Epub 2017 Jan 10
doi: 10.1016/j.jns.2017.01.033.
<span class="bold">PMID: </span><a href="/pubmed/28320194" target="_blank">28320194</a><a href="/pmc/articles/PMC5363284" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27855131">Patellar Tendinopathy: Diagnosis and Treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Figueroa D,
Figueroa F,
Calvo R</span><br />
<span class="medgenPMjournal">J Am Acad Orthop Surg</span>
2016 Dec;24(12):e184-e192.
doi: 10.5435/JAAOS-D-15-00703.
<span class="bold">PMID: </span><a href="/pubmed/27855131" target="_blank">27855131</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23398951">Lateral epicondylitis of the elbow.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tosti R,
Jennings J,
Sewards JM</span><br />
<span class="medgenPMjournal">Am J Med</span>
2013 Apr;126(4):357.e1-6.
Epub 2013 Feb 8
doi: 10.1016/j.amjmed.2012.09.018.
<span class="bold">PMID: </span><a href="/pubmed/23398951" target="_blank">23398951</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23250766">Inclusion body myositis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dimachkie MM,
Barohn RJ</span><br />
<span class="medgenPMjournal">Curr Neurol Neurosci Rep</span>
2013 Jan;13(1):321.
doi: 10.1007/s11910-012-0321-4.
<span class="bold">PMID: </span><a href="/pubmed/23250766" target="_blank">23250766</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22230308">Osteoarthritis: diagnosis and treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sinusas K</span><br />
<span class="medgenPMjournal">Am Fam Physician</span>
2012 Jan 1;85(1):49-56.
<span class="bold">PMID: </span><a href="/pubmed/22230308" target="_blank">22230308</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disorder%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (240)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/36708320">Omaveloxolone: an activator of Nrf2 for the treatment of Friedreich ataxia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Profeta V,
McIntyre K,
Wells M,
Park C,
Lynch DR</span><br />
<span class="medgenPMjournal">Expert Opin Investig Drugs</span>
2023 Jan;32(1):5-16.
Epub 2023 Feb 8
doi: 10.1080/13543784.2023.2173063.
<span class="bold">PMID: </span><a href="/pubmed/36708320" target="_blank">36708320</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23250766">Inclusion body myositis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dimachkie MM,
Barohn RJ</span><br />
<span class="medgenPMjournal">Curr Neurol Neurosci Rep</span>
2013 Jan;13(1):321.
doi: 10.1007/s11910-012-0321-4.
<span class="bold">PMID: </span><a href="/pubmed/23250766" target="_blank">23250766</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22230308">Osteoarthritis: diagnosis and treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sinusas K</span><br />
<span class="medgenPMjournal">Am Fam Physician</span>
2012 Jan 1;85(1):49-56.
<span class="bold">PMID: </span><a href="/pubmed/22230308" target="_blank">22230308</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16190135">Osteoarthritis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mahajan A,
Verma S,
Tandon V</span><br />
<span class="medgenPMjournal">J Assoc Physicians India</span>
2005 Jul;53:634-41.
<span class="bold">PMID: </span><a href="/pubmed/16190135" target="_blank">16190135</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12897215">Osteoarthritis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Haq I,
Murphy E,
Dacre J</span><br />
<span class="medgenPMjournal">Postgrad Med J</span>
2003 Jul;79(933):377-83.
doi: 10.1136/pmj.79.933.377.
<span class="bold">PMID: </span><a href="/pubmed/12897215" target="_blank">12897215</a><a href="/pmc/articles/PMC1742743" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disorder%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (137)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/36980302">Biomarkers Assessing Endothelial Dysfunction in Alzheimer's Disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Custodia A,
Aramburu-Núñez M,
Rodríguez-Arrizabalaga M,
Pías-Peleteiro JM,
Vázquez-Vázquez L,
Camino-Castiñeiras J,
Aldrey JM,
Castillo J,
Ouro A,
Sobrino T,
Romaus-Sanjurjo D</span><br />
<span class="medgenPMjournal">Cells</span>
2023 Mar 22;12(6)
doi: 10.3390/cells12060962.
<span class="bold">PMID: </span><a href="/pubmed/36980302" target="_blank">36980302</a><a href="/pmc/articles/PMC10047803" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31473667">The Chiari I malformation.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McClugage SG,
Oakes WJ</span><br />
<span class="medgenPMjournal">J Neurosurg Pediatr</span>
2019 Sep 1;24(3):217-226.
doi: 10.3171/2019.5.PEDS18382.
<span class="bold">PMID: </span><a href="/pubmed/31473667" target="_blank">31473667</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30707189">Primary Progressive Aphasias and Apraxia of Speech.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Botha H,
Josephs KA</span><br />
<span class="medgenPMjournal">Continuum (Minneap Minn)</span>
2019 Feb;25(1):101-127.
doi: 10.1212/CON.0000000000000699.
<span class="bold">PMID: </span><a href="/pubmed/30707189" target="_blank">30707189</a><a href="/pmc/articles/PMC6548538" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25654663">Aggressive Periodontitis: microbes and host response, who to blame?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nibali L</span><br />
<span class="medgenPMjournal">Virulence</span>
2015;6(3):223-8.
doi: 10.4161/21505594.2014.986407.
<span class="bold">PMID: </span><a href="/pubmed/25654663" target="_blank">25654663</a><a href="/pmc/articles/PMC4601283" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9061754">Huntington's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Craufurd D</span><br />
<span class="medgenPMjournal">Prenat Diagn</span>
1996 Dec;16(13):1237-45.
doi: 10.1002/(SICI)1097-0223(199612)16:13&lt;1237::AID-PD98&gt;3.0.CO;2-T.
<span class="bold">PMID: </span><a href="/pubmed/9061754" target="_blank">9061754</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disorder%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (115)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/34185124">Emerging role of integrated PET-MRI in osteoarthritis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jena A,
Taneja S,
Rana P,
Goyal N,
Vaish A,
Botchu R,
Vaishya R</span><br />
<span class="medgenPMjournal">Skeletal Radiol</span>
2021 Dec;50(12):2349-2363.
Epub 2021 Jun 29
doi: 10.1007/s00256-021-03847-z.
<span class="bold">PMID: </span><a href="/pubmed/34185124" target="_blank">34185124</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29293456">LINE-1 activity and regulation in cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rodic N</span><br />
<span class="medgenPMjournal">Front Biosci (Landmark Ed)</span>
2018 Mar 1;23(9):1680-1686.
doi: 10.2741/4666.
<span class="bold">PMID: </span><a href="/pubmed/29293456" target="_blank">29293456</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25654663">Aggressive Periodontitis: microbes and host response, who to blame?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nibali L</span><br />
<span class="medgenPMjournal">Virulence</span>
2015;6(3):223-8.
doi: 10.4161/21505594.2014.986407.
<span class="bold">PMID: </span><a href="/pubmed/25654663" target="_blank">25654663</a><a href="/pmc/articles/PMC4601283" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12622457">Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kimmatkar N,
Thawani V,
Hingorani L,
Khiyani R</span><br />
<span class="medgenPMjournal">Phytomedicine</span>
2003 Jan;10(1):3-7.
doi: 10.1078/094471103321648593.
<span class="bold">PMID: </span><a href="/pubmed/12622457" target="_blank">12622457</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9061754">Huntington's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Craufurd D</span><br />
<span class="medgenPMjournal">Prenat Diagn</span>
1996 Dec;16(13):1237-45.
doi: 10.1002/(SICI)1097-0223(199612)16:13&lt;1237::AID-PD98&gt;3.0.CO;2-T.
<span class="bold">PMID: </span><a href="/pubmed/9061754" target="_blank">9061754</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disorder%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (178)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/39662839">The complex relationship between gut microbiota and Alzheimer's disease: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zhou XP,
Sun LB,
Liu WH,
Zhu WM,
Li LC,
Song XY,
Xing JP,
Gao SH</span><br />
<span class="medgenPMjournal">Ageing Res Rev</span>
2025 Feb;104:102637.
Epub 2024 Dec 9
doi: 10.1016/j.arr.2024.102637.
<span class="bold">PMID: </span><a href="/pubmed/39662839" target="_blank">39662839</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35421194">Retinal biomarkers of Cerebral Small Vessel Disease: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Biffi E,
Turple Z,
Chung J,
Biffi A</span><br />
<span class="medgenPMjournal">PLoS One</span>
2022;17(4):e0266974.
Epub 2022 Apr 14
doi: 10.1371/journal.pone.0266974.
<span class="bold">PMID: </span><a href="/pubmed/35421194" target="_blank">35421194</a><a href="/pmc/articles/PMC9009626" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34206010">Meta-Analysis of Adipose Tissue Derived Cell-Based Therapy for the Treatment of Knee Osteoarthritis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Agarwal N,
Mak C,
Bojanic C,
To K,
Khan W</span><br />
<span class="medgenPMjournal">Cells</span>
2021 Jun 1;10(6)
doi: 10.3390/cells10061365.
<span class="bold">PMID: </span><a href="/pubmed/34206010" target="_blank">34206010</a><a href="/pmc/articles/PMC8228374" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34200812">Diabetes Mellitus and Amyotrophic Lateral Sclerosis: A Systematic Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ferri L,
Ajdinaj P,
Rispoli MG,
Carrarini C,
Barbone F,
D'Ardes D,
Capasso M,
Muzio AD,
Cipollone F,
Onofrj M,
Bonanni L</span><br />
<span class="medgenPMjournal">Biomolecules</span>
2021 Jun 10;11(6)
doi: 10.3390/biom11060867.
<span class="bold">PMID: </span><a href="/pubmed/34200812" target="_blank">34200812</a><a href="/pmc/articles/PMC8230511" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28734792">Genetic factors of cervical spondylotic myelopathy-a systemic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang G,
Cao Y,
Wu T,
Duan C,
Wu J,
Hu J,
Lu H</span><br />
<span class="medgenPMjournal">J Clin Neurosci</span>
2017 Oct;44:89-94.
Epub 2017 Jul 19
doi: 10.1016/j.jocn.2017.06.043.
<span class="bold">PMID: </span><a href="/pubmed/28734792" target="_blank">28734792</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disorder%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10)</a></div></div>
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