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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="books">Books</option><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen" class="last">MedGen</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'17659',linkname:'',idsfromresult:'57826',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67d3e7eff59ffc792642949e" data-hid="MCID_67d2a666fe1ad803e8633767" data-qky="17659" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">RAP2C</span> RAP2C, member of RAS oncogene family [ <em class="tax">Homo sapiens</em> (human)
]
</h1>
<span class="geneid">Gene ID: 57826, updated on
8-Mar-2025</span>
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<div class="rprt-section gene-summary">
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<dl id="summaryDl">
<dt class="noline"> Official
Symbol</dt>
<dd class="noline">RAP2C<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt> Official
Full Name</dt>
<dd>RAP2C, member of RAS oncogene family<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt>Primary source</dt>
<dd>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:21165" data-gblink-text="Ensembl">HGNC:HGNC:21165</a>
</dd>
<dt>See related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENSG00000123728" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000123728">Ensembl:ENSG00000123728</a>
<a href="https://www.ncbi.nlm.nih.gov/omim/301016" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=301016">MIM:301016;</a>
<a href="https://www.alliancegenome.org/gene/HGNC:21165" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=HGNC:21165">AllianceGenome:HGNC:21165</a>
</dd>
<dt>Gene type</dt>
<dd>protein coding</dd>
<dt>RefSeq status</dt>
<dd>REVIEWED</dd>
<dt>Organism</dt>
<dd class="tax">
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=9606">Homo sapiens</a>
</dd>
<dt>Lineage</dt>
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
<dt>Summary</dt>
<dd>The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]</dd>
<dt>Expression</dt>
<dd>Ubiquitous expression in endometrium (RPKM 31.6), bone marrow (RPKM 18.9) and 24 other tissues <a href="#gene-expression">See more</a></dd>
<dt>Orthologs</dt>
<dd class="ortholog-links">
<a href="https://www.ncbi.nlm.nih.gov/gene/72065">mouse</a>
<a href="/gene/57826/ortholog/">all</a>
</dd>
<dt style="padding-top:.5em;">
<span class="new-icon">NEW</span>
</dt>
<dd style="padding-top:.5em;">
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/57826/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
<br />
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/57826/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
</dd>
</dl>
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<div class="rprt-section gene-genomic-context">
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<div style="float:right"><span>See RAP2C in </span><a href="/genome/gdv/?context=gene&amp;acc=57826" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
<dl class="dl-chr-info" style="float:left;margin-top:0;">
<dt>Location: </dt>
<dd>
<span style="display:inline-block;">Xq26.2</span>
</dd>
</dl>
</div>
<dl class="dl-chr-info exon-count">
<dt>Exon count: </dt>
<dd>9</dd>
</dl>
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="">
<thead>
<tr>
<th style="max-width:15%">Annotation release</th>
<th style="max-width:10%">Status</th>
<th>Assembly</th>
<th>
<span title="Chromosome">Chr</span>
</th>
<th>Location</th>
</tr>
</thead>
<tbody>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=57826&amp;link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
<td>X</td>
<td>NC_000023.11 (132203025..132219447, complement) </td>
</tr>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=57826&amp;link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
<td>X</td>
<td>NC_060947.1 (130527262..130543665, complement) </td>
</tr>
<tr>
<td>RS_2024_09</td>
<td>previous assembly</td>
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=57826&amp;link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
<td>X</td>
<td>NC_000023.10 (131337053..131353475, complement) </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<p class="withnote margin_t2em"><strong>Chromosome X - NC_000023.11</strong><img usemap="#nbrMap57826_568815575" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=57826&amp;nuc_gi=568815575&amp;n0=FRMD7&amp;n1=LOC130068711&amp;n2=LOC127898318&amp;n3=AGKP2&amp;n4=LOC127898319&amp;n5=LOC127898320&amp;n6=RAP2C&amp;n7=LOC130068712&amp;n8=LOC130068713&amp;n9=RAP2C-AS1&amp;n10=LOC130068714&amp;n11=LOC130068715&amp;n12=LOC127898321&amp;n13=LOC125467784&amp;n14=LOC126863320&amp;n15=MBNL3&amp;n16=LOC127898322&amp;n17=LOC130068716&amp;n18=LOC126863321&amp;n19=RNU6-98P" /><map name="nbrMap57826_568815575" id="nbrMap57826_568815575">
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 21004')" onMouseOut="hidetip()" coords="13,23,83,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21004" href="/gene/130068711" />
<area shape="rect" onMouseOver="showtip(this,event,'NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:131253207-131254142')" onMouseOut="hidetip()" coords="32,35,102,43" alt="Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:131253207-131254142" href="/gene/127898318" />
<area shape="rect" onMouseOver="showtip(this,event,'FERM domain containing 7')" onMouseOut="hidetip()" coords="37,47,100,55" alt="Neighboring gene FERM domain containing 7" href="/gene/90167" />
<area shape="rect" onMouseOver="showtip(this,event,'NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:131295346-131295904')" onMouseOut="hidetip()" coords="62,59,132,67" alt="Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:131295346-131295904" href="/gene/127898319" />
<area shape="rect" onMouseOver="showtip(this,event,'NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:131295905-131296461')" onMouseOut="hidetip()" coords="63,71,133,79" alt="Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:131295905-131296461" href="/gene/127898320" />
<area shape="rect" onMouseOver="showtip(this,event,'AGK pseudogene 2')" onMouseOut="hidetip()" coords="75,83,110,91" alt="Neighboring gene AGK pseudogene 2" href="/gene/392543" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 21005')" onMouseOut="hidetip()" coords="102,23,172,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21005" href="/gene/130068712" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 21006')" onMouseOut="hidetip()" coords="103,35,173,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21006" href="/gene/130068713" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29971')" onMouseOut="hidetip()" coords="104,47,174,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29971" href="/gene/130068714" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29972')" onMouseOut="hidetip()" coords="104,95,174,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29972" href="/gene/130068715" />
<area shape="rect" onMouseOver="showtip(this,event,'NANOG hESC enhancer GRCh37_chrX:131357781-131358310')" onMouseOut="hidetip()" coords="107,107,177,115" alt="Neighboring gene NANOG hESC enhancer GRCh37_chrX:131357781-131358310" href="/gene/127898321" />
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 7036')" onMouseOut="hidetip()" coords="116,83,186,91" alt="Neighboring gene Sharpr-MPRA regulatory region 7036" href="/gene/125467784" />
<area shape="rect" onMouseOver="showtip(this,event,'RAP2C antisense RNA 1')" onMouseOut="hidetip()" coords="118,119,318,127" alt="Neighboring gene RAP2C antisense RNA 1" href="/gene/101928578" />
<area shape="rect" onMouseOver="showtip(this,event,'BRD4-independent group 4 enhancer GRCh37_chrX:131423741-131424940')" onMouseOut="hidetip()" coords="154,59,224,67" alt="Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:131423741-131424940" href="/gene/126863320" />
<area shape="rect" onMouseOver="showtip(this,event,'OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:131545832-131546540')" onMouseOut="hidetip()" coords="241,23,311,31" alt="Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:131545832-131546540" href="/gene/127898322" />
<area shape="rect" onMouseOver="showtip(this,event,'muscleblind like splicing regulator 3')" onMouseOut="hidetip()" coords="246,35,359,43" alt="Neighboring gene muscleblind like splicing regulator 3" href="/gene/55796" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 21007')" onMouseOut="hidetip()" coords="296,47,366,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21007" href="/gene/130068716" />
<area shape="rect" onMouseOver="showtip(this,event,'CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:131625860-131627059')" onMouseOut="hidetip()" coords="298,59,368,67" alt="Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:131625860-131627059" href="/gene/126863321" />
<area shape="rect" onMouseOver="showtip(this,event,'RNA, U6 small nuclear 98, pseudogene')" onMouseOut="hidetip()" coords="373,23,423,31" alt="Neighboring gene RNA, U6 small nuclear 98, pseudogene" href="/gene/106479609" />
</map>
</p>
</div>
</div>
<div class="rprt-section gene-genomic-regions-transcripts-products">
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
<h2 id="header-genomic-regions-transcripts-products">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
</div>
<div>
<p class="choose">
<label for="accession" class="label">Genomic Sequence: </label>
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="57826">
<option value="NC_000023.11_132203024_132219446">NC_000023.11 Chromosome X Reference GRCh38.p14 Primary Assembly</option>
<option value="NC_060947.1_130527261_130543664">NC_060947.1 Chromosome X Alternate T2T-CHM13v2.0</option>
<option value="NC_000023.10_131337052_131353474">NC_000023.10 Chromosome X Reference GRCh37.p13 Primary Assembly</option>
</select>
</p>
</div>
<div id="NC_000023" class="divAccession">
<div class="seq-viewer">
<p class="note-link">
<strong>Go to nucleotide:</strong>
<a title="Nucleotide Graphic report" href="/nuccore/NC_000023.11?report=graph&amp;from=132200561&amp;to=132221909&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_000023.11">Graphics</a>
<a title="Nucleotide FASTA report" href="/nuccore/NC_000023.11?report=fasta&amp;from=132203025&amp;to=132219447&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_000023.11">FASTA</a>
<a title="Nucleotide GenBank report" href="/nuccore/NC_000023.11?report=genbank&amp;from=132203025&amp;to=132219447&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_000023.11">GenBank</a>
</p>
<div id="divNC_000023" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000023.11&amp;from=132200561&amp;to=132221909&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40">
<a href="?appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000023.11&amp;from=132200561&amp;to=132221909&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40"></a>
</div>
</div>
</div>
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000023.11" sid="1" type="hidden" id="nucleotideLink_NC_000023_11_132203024_132219446" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000023.11?report=graph&amp;amp;from=132200561&amp;amp;to=132221909&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_000023.11&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000023.11?report=fasta&amp;amp;from=132203025&amp;amp;to=132219447&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_000023.11&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000023.11?report=genbank&amp;amp;from=132203025&amp;amp;to=132219447&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_000023.11&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000023.11" sid="1" type="hidden" id="relString_NC_000023_11_132203024_132219446" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000023.11&amp;amp;from=132200561&amp;amp;to=132221909&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060947.1" sid="1" type="hidden" id="nucleotideLink_NC_060947_1_130527261_130543664" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_060947.1?report=graph&amp;amp;from=130524801&amp;amp;to=130546124&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_060947.1&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_060947.1?report=fasta&amp;amp;from=130527262&amp;amp;to=130543665&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_060947.1&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_060947.1?report=genbank&amp;amp;from=130527262&amp;amp;to=130543665&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_060947.1&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060947.1" sid="1" type="hidden" id="relString_NC_060947_1_130527261_130543664" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_060947.1&amp;amp;from=130524801&amp;amp;to=130546124&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000023.10" sid="1" type="hidden" id="nucleotideLink_NC_000023_10_131337052_131353474" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000023.10?report=graph&amp;amp;from=131334589&amp;amp;to=131355937&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_000023.10&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000023.10?report=fasta&amp;amp;from=131337053&amp;amp;to=131353475&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_000023.10&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000023.10?report=genbank&amp;amp;from=131337053&amp;amp;to=131353475&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=57826&amp;amp;link_uid=NC_000023.10&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000023.10" sid="1" type="hidden" id="relString_NC_000023_10_131337052_131353474" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000023.10&amp;amp;from=131334589&amp;amp;to=131355937&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25" />
</div>
</div>
<div class="rprt-section gene-gene-expression">
<section class="rprt-section-header" id="gene-expression">
<h2 id="header-gene-expression">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Expression</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">
<a href="/gene/57826/?report=expression" data-url="/gene/57826/?report=expression" id="gene-expression-see-details">See details</a>
</div>
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/57826" data-report-type="summary">
<div>
<script type="text/javascript">
window.tissues_data = {'adrenal 10wk': {'id': '57826_Adrenal_10wk_PRJNA270632', 'gene': 57826, 'source_name': 'adrenal 10wk', 'full_rpkm': 10.8468, 'exp_rpkm': 10.8, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432248823831}, 'adrenal 16wk': {'id': '57826_Adrenal_16wk_PRJNA270632', 'gene': 57826, 'source_name': 'adrenal 16wk', 'full_rpkm': 8.72531, 'exp_rpkm': 8.73, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432248823832}, 'adrenal 18wk': {'id': '57826_Adrenal_18wk_PRJNA270632', 'gene': 57826, 'source_name': 'adrenal 18wk', 'full_rpkm': 9.36919, 'exp_rpkm': 9.37, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432248823833}, 'adrenal 20wk': {'id': '57826_Adrenal_20wk_PRJNA270632', 'gene': 57826, 'source_name': 'adrenal 20wk', 'full_rpkm': 8.89278, 'exp_rpkm': 8.89, 'var': 0.278108, 'project_desc': 'PRJNA270632', '_version_': 1785734432248823834}, 'heart 10wk': {'id': '57826_Heart_10wk;_PRJNA270632', 'gene': 57826, 'source_name': 'heart 10wk', 'full_rpkm': 5.67209, 'exp_rpkm': 5.67, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432248823835}, 'heart 11wk': {'id': '57826_Heart_11wk;_PRJNA270632', 'gene': 57826, 'source_name': 'heart 11wk', 'full_rpkm': 4.07643, 'exp_rpkm': 4.08, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432248823836}, 'heart 17wk': {'id': '57826_Heart_17wk;_PRJNA270632', 'gene': 57826, 'source_name': 'heart 17wk', 'full_rpkm': 2.38558, 'exp_rpkm': 2.39, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432248823837}, 'heart 18wk': {'id': '57826_Heart_18wk;_PRJNA270632', 'gene': 57826, 'source_name': 'heart 18wk', 'full_rpkm': 2.53916, 'exp_rpkm': 2.54, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432248823838}, 'heart 20wk': {'id': '57826_Heart_20wk_PRJNA270632', 'gene': 57826, 'source_name': 'heart 20wk', 'full_rpkm': 2.87191, 'exp_rpkm': 2.87, 'var': 0.656643, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872384}, 'intestine 10wk': {'id': '57826_Intestine_10wk_PRJNA270632', 'gene': 57826, 'source_name': 'intestine 10wk', 'full_rpkm': 4.8844, 'exp_rpkm': 4.88, 'var': 2.28678, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872385}, 'intestine 11wk': {'id': '57826_Intestine_11wk_PRJNA270632', 'gene': 57826, 'source_name': 'intestine 11wk', 'full_rpkm': 5.4417, 'exp_rpkm': 5.44, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872386}, 'intestine 15wk': {'id': '57826_Intestine_15wk_PRJNA270632', 'gene': 57826, 'source_name': 'intestine 15wk', 'full_rpkm': 4.99355, 'exp_rpkm': 4.99, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872387}, 'intestine 17wk': {'id': '57826_Intestine_17wk_PRJNA270632', 'gene': 57826, 'source_name': 'intestine 17wk', 'full_rpkm': 1.80044, 'exp_rpkm': 1.8, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872388}, 'intestine 20wk': {'id': '57826_Intestine_20wk_PRJNA270632', 'gene': 57826, 'source_name': 'intestine 20wk', 'full_rpkm': 5.54792, 'exp_rpkm': 5.55, 'var': 0.510954, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872389}, 'kidney 10wk': {'id': '57826_Kidney_10wk_PRJNA270632', 'gene': 57826, 'source_name': 'kidney 10wk', 'full_rpkm': 6.66518, 'exp_rpkm': 6.67, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872390}, 'kidney 16wk': {'id': '57826_Kidney_16wk_PRJNA270632', 'gene': 57826, 'source_name': 'kidney 16wk', 'full_rpkm': 2.32839, 'exp_rpkm': 2.33, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872391}, 'kidney 20wk': {'id': '57826_Kidney_20wk_PRJNA270632', 'gene': 57826, 'source_name': 'kidney 20wk', 'full_rpkm': 1.11735, 'exp_rpkm': 1.12, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872392}, 'lung 10wk': {'id': '57826_Lung_10wk_PRJNA270632', 'gene': 57826, 'source_name': 'lung 10wk', 'full_rpkm': 3.8322, 'exp_rpkm': 3.83, 'var': 0.0107081, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872393}, 'lung 17wk': {'id': '57826_Lung_17wk_PRJNA270632', 'gene': 57826, 'source_name': 'lung 17wk', 'full_rpkm': 4.2225, 'exp_rpkm': 4.22, 'var': 0.0273144, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872394}, 'lung 20wk': {'id': '57826_Lung_20wk_PRJNA270632', 'gene': 57826, 'source_name': 'lung 20wk', 'full_rpkm': 3.17915, 'exp_rpkm': 3.18, 'var': 1.649518, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872395}, 'stomach 10wk': {'id': '57826_Stomach_10wk_PRJNA270632', 'gene': 57826, 'source_name': 'stomach 10wk', 'full_rpkm': 3.5234, 'exp_rpkm': 3.52, 'var': 0.001747144, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872396}, 'stomach 16wk': {'id': '57826_Stomach_16wk_PRJNA270632', 'gene': 57826, 'source_name': 'stomach 16wk', 'full_rpkm': 3.22027, 'exp_rpkm': 3.22, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872397}, 'stomach 18wk': {'id': '57826_Stomach_18wk_PRJNA270632', 'gene': 57826, 'source_name': 'stomach 18wk', 'full_rpkm': 3.43149, 'exp_rpkm': 3.43, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872398}, 'stomach 20wk': {'id': '57826_Stomach_20wk_PRJNA270632', 'gene': 57826, 'source_name': 'stomach 20wk', 'full_rpkm': 3.21648, 'exp_rpkm': 3.22, 'var': 0.1664625, 'project_desc': 'PRJNA270632', '_version_': 1785734432249872399}};
window.details_data = {"adrenal 10wk": [{"id": "metadata_9606_SAMN03267754", "gene": 57826, "sample_id": "SAMN03267754", "full_rpkm": 10.8468, "exp_rpkm": 10.8, "exp_total": 227346, "project_desc": "PRJNA270632", "_version_": 1785734387345653765, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 10wk", "exp_Mcount": 4852.92}], "adrenal 16wk": [{"id": "metadata_9606_SAMN03267755", "gene": 57826, "sample_id": "SAMN03267755", "full_rpkm": 8.72531, "exp_rpkm": 8.73, "exp_total": 273941, "project_desc": "PRJNA270632", "_version_": 1785734387345653764, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 16wk", "exp_Mcount": 7269.31}], "adrenal 18wk": [{"id": "metadata_9606_SAMN03267761", "gene": 57826, "sample_id": "SAMN03267761", "full_rpkm": 9.36919, "exp_rpkm": 9.37, "exp_total": 270124, "project_desc": "PRJNA270632", "_version_": 1785734387345653763, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 18wk", "exp_Mcount": 6675.41}], "adrenal 20wk": [{"id": "metadata_9606_SAMN03267762", "gene": 57826, "sample_id": "SAMN03267762", "full_rpkm": 8.36542, "exp_rpkm": 8.37, "exp_total": 273208, "project_desc": "PRJNA270632", "_version_": 1785734387345653761, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 7561.75}, {"id": "metadata_9606_SAMN03267753", "gene": 57826, "sample_id": "SAMN03267753", "full_rpkm": 9.42014, "exp_rpkm": 9.42, "exp_total": 270477, "project_desc": "PRJNA270632", "_version_": 1785734387345653762, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 6647.98}], "heart 10wk": [{"id": "metadata_9606_SAMN03267750", "gene": 57826, "sample_id": "SAMN03267750", "full_rpkm": 5.67209, "exp_rpkm": 5.67, "exp_total": 130822, "project_desc": "PRJNA270632", "_version_": 1785734387345653760, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 10wk", "exp_Mcount": 5340.16}], "heart 11wk": [{"id": "metadata_9606_SAMN03267763", "gene": 57826, "sample_id": "SAMN03267763", "full_rpkm": 4.07643, "exp_rpkm": 4.08, "exp_total": 104529, "project_desc": "PRJNA270632", "_version_": 1785734387344605210, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 11wk", "exp_Mcount": 5937.09}], "heart 17wk": [{"id": "metadata_9606_SAMN03267757", "gene": 57826, "sample_id": "SAMN03267757", "full_rpkm": 2.38558, "exp_rpkm": 2.39, "exp_total": 81475, "project_desc": "PRJNA270632", "_version_": 1785734387344605209, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 17wk", "exp_Mcount": 7907.66}], "heart 18wk": [{"id": "metadata_9606_SAMN03267751", "gene": 57826, "sample_id": "SAMN03267751", "full_rpkm": 2.53916, "exp_rpkm": 2.54, "exp_total": 69977, "project_desc": "PRJNA270632", "_version_": 1785734387344605208, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 18wk", "exp_Mcount": 6380.91}], "heart 20wk": [{"id": "metadata_9606_SAMN03267756", "gene": 57826, "sample_id": "SAMN03267756", "full_rpkm": 2.60433, "exp_rpkm": 2.6, "exp_total": 122114, "project_desc": "PRJNA270632", "_version_": 1785734387344605205, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 10856.4}, {"id": "metadata_9606_SAMN03267764", "gene": 57826, "sample_id": "SAMN03267764", "full_rpkm": 3.97073, "exp_rpkm": 3.97, "exp_total": 87421, "project_desc": "PRJNA270632", "_version_": 1785734387344605206, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5097.56}, {"id": "metadata_9606_SAMN03267760", "gene": 57826, "sample_id": "SAMN03267760", "full_rpkm": 2.04069, "exp_rpkm": 2.04, "exp_total": 52830, "project_desc": "PRJNA270632", "_version_": 1785734387344605207, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5994.06}], "intestine 10wk": 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"metadata_9606_SAMN03267775", "gene": 57826, "sample_id": "SAMN03267775", "full_rpkm": 4.99355, "exp_rpkm": 4.99, "exp_total": 85847, "project_desc": "PRJNA270632", "_version_": 1785734387344605201, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 15wk", "exp_Mcount": 3980.45}], "intestine 17wk": [{"id": "metadata_9606_SAMN03267782", "gene": 57826, "sample_id": "SAMN03267782", "full_rpkm": 1.80044, "exp_rpkm": 1.8, "exp_total": 75161, "project_desc": "PRJNA270632", "_version_": 1785734387344605200, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 17wk", "exp_Mcount": 9665.65}], "intestine 20wk": [{"id": "metadata_9606_SAMN03267766", "gene": 57826, "sample_id": "SAMN03267766", "full_rpkm": 4.83311, "exp_rpkm": 4.83, "exp_total": 86863, "project_desc": "PRJNA270632", "_version_": 1785734387344605198, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 4161.26}, {"id": 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[{"id": "metadata_9606_SAMN03267777", "gene": 57826, "sample_id": "SAMN03267777", "full_rpkm": 1.11735, "exp_rpkm": 1.12, "exp_total": 49610, "project_desc": "PRJNA270632", "_version_": 1785734387344605195, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 20wk", "exp_Mcount": 10280.0}], "lung 10wk": [{"id": "metadata_9606_SAMN03267770", "gene": 57826, "sample_id": "SAMN03267770", "full_rpkm": 3.72872, "exp_rpkm": 3.73, "exp_total": 95865, "project_desc": "PRJNA270632", "_version_": 1785734387344605193, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5952.75}, {"id": "metadata_9606_SAMN03267767", "gene": 57826, "sample_id": "SAMN03267767", "full_rpkm": 3.93568, "exp_rpkm": 3.94, "exp_total": 88922, "project_desc": "PRJNA270632", "_version_": 1785734387344605194, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5231.26}], "lung 17wk": [{"id": 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window.taxId = 9606
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<div>
<select name="p" id="project-selector">
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
Tissue-specific circular RNA induction during human fetal development
</option>
<option value="SRP056969" data-bioproject="PRJNA280600">
RNA sequencing of total RNA from 20 human tissues
</option>
<option value="ERP003613" data-bioproject="PRJEB4337">
HPA RNA-seq normal tissues
</option>
</select>
<ul id="project-summary">
<li id="project-summary-title">Project title:
Tissue-specific circular RNA induction during human fetal development
</li>
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
</li>
<li id="project-summary-pubs">Publication:
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
</li>
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
</ul>
<div id="gene-expr-details" class="expression-chart"></div>
</div>
</div>
</div>
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
<script type="text/javascript">
google.charts.load('current', {
'packages':[ 'corechart']
});
</script>
</div>
</div>
</div>
<div class="rprt-section gene-bibliography">
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
<div class="rprt-section-body" style="">
<div class="generif-pubmed">
<h3 id="relatedarticlesinpubmed">
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
</h3>
<div class="generefbl-link">
<ol class="generef-link">
<li>
<a href="/pubmed/19784953/" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=19784953">A novel approach to tag and identify geranylgeranylated proteins.</a>
<span class="pubmed-auth-date"> Chan LN, <em>et al</em>. Electrophoresis, 2009 Oct. PMID 19784953, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC2855049/" ref="ordinalpos=0&amp;ncbi_uid=57826&amp;link_uid=PMC2855049">Free PMC Article</a></span></span>
</li>
<li>
<a href="/pubmed/21668950/" ref="ordinalpos=2&amp;ncbi_uid=57826&amp;link_uid=21668950">A computational approach to candidate gene prioritization for X-linked mental retardation using annotation-based binary filtering and motif-based linear discriminatory analysis.</a>
<span class="pubmed-auth-date"> Lombard Z, <em>et al</em>. Biol Direct, 2011 Jun 13. PMID 21668950, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC3142252/" ref="ordinalpos=0&amp;ncbi_uid=57826&amp;link_uid=PMC3142252">Free PMC Article</a></span></span>
</li>
<li>
<a href="/pubmed/17447155/" ref="ordinalpos=3&amp;ncbi_uid=57826&amp;link_uid=17447155">Cloning and characterization of the human gene RAP2C, a novel member of Ras family, which activates transcriptional activities of SRE.</a>
<span class="pubmed-auth-date"> Guo Z, <em>et al</em>. Mol Biol Rep, 2007 Sep. PMID 17447155</span>
</li>
<li>
<a href="/pubmed/33302819/" ref="ordinalpos=4&amp;ncbi_uid=57826&amp;link_uid=33302819">microRNA-195 Promotes Small Cell Lung Cancer Cell Apoptosis via Inhibiting Rap2C Protein-Dependent MAPK Signal Transduction.</a>
<span class="pubmed-auth-date"> Tong J, <em>et al</em>. Technol Cancer Res Treat, 2020 Jan-Dec. PMID 33302819, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC7734482/" ref="ordinalpos=0&amp;ncbi_uid=57826&amp;link_uid=PMC7734482">Free PMC Article</a></span></span>
</li>
<li>
<a href="/pubmed/31541458/" ref="ordinalpos=5&amp;ncbi_uid=57826&amp;link_uid=31541458">MicroRNA-188-5p promotes apoptosis and inhibits cell proliferation of breast cancer cells via the MAPK signaling pathway by targeting Rap2c.</a>
<span class="pubmed-auth-date"> Zhu X, <em>et al</em>. J Cell Physiol, 2020 Mar. PMID 31541458</span>
</li>
</ol>
<p class="see-all-pm">
<a href="/pubmed?LinkName=gene_pubmed&amp;from_uid=57826" title="See all 51 citations in Pubmed">See all (51) citations in PubMed</a>
</p>
</div>
</div>
<div class="generif-pubmed generif">
<h3 id="generifsgenereferencesintofunctions">
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
</h3>
<div>
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
<div class="generefbl-link">
<ol class="generef-link">
<li class="gene-rif-popper">
<a href="/pubmed/36214632" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=36214632">The LncRNA LENOX Interacts with RAP2C to Regulate Metabolism and Promote Resistance to MAPK Inhibition in Melanoma.</a>
<div id="gene-popper1" class="gene-rif-popper">Title: The LncRNA LENOX Interacts with RAP2C to Regulate Metabolism and Promote Resistance to MAPK Inhibition in Melanoma.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/34676879" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=34676879">MicroRNA200c3p suppresses intervertebral disc degeneration by targeting RAP2C/ERK signaling.</a>
<div id="gene-popper2" class="gene-rif-popper">Title: MicroRNA200c3p suppresses intervertebral disc degeneration by targeting RAP2C/ERK signaling.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/33302819" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=33302819">microRNA-195 Promotes Small Cell Lung Cancer Cell Apoptosis via Inhibiting Rap2C Protein-Dependent MAPK Signal Transduction.</a>
<div id="gene-popper3" class="gene-rif-popper">Title: microRNA-195 Promotes Small Cell Lung Cancer Cell Apoptosis via Inhibiting Rap2C Protein-Dependent MAPK Signal Transduction.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/31541458" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=31541458">MicroRNA-188-5p promotes apoptosis and inhibits cell proliferation of breast cancer cells via the MAPK signaling pathway by targeting Rap2c.</a>
<div id="gene-popper4" class="gene-rif-popper">Title: MicroRNA-188-5p promotes apoptosis and inhibits cell proliferation of breast cancer cells via the MAPK signaling pathway by targeting Rap2c.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/28714326" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=28714326">Study found that SCII upregulated the expression of miR-204 and downregulated the expression of RAP2C; that hypoxia increased the expression of miR-204 and decreased the expression of RAP2C, and overexpression of RAP2C attenuates the effect of hypoxia on apoptosis rate; and miR-204 could directly bind to RAP2C, and could regulate the expression of RAP2C.</a>
<div id="gene-popper5" class="gene-rif-popper">Title: Spinal cord ischemia-reperfusion causes damage of neurocyte by inhibiting RAP2C.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/23885123" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=23885123">JAM-A regulates epithelial permeability via association with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and control contraction of the apical cytoskeleton.</a>
<div id="gene-popper6" class="gene-rif-popper">Title: JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/17447155" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=17447155">RAP2C is a novel member of the Ras family, belonging to the Rap branch of small GTPase proteins and may be involved in SRE-mediated gene transcription.</a>
<div id="gene-popper7" class="gene-rif-popper">Title: Cloning and characterization of the human gene RAP2C, a novel member of Ras family, which activates transcriptional activities of SRE.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/16213650" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=16213650">This work demonstrates that Rap2C is a new member of the Rap2 subfamily of proteins, able to bind guanine nucleotides with peculiar properties, and differently expressed by various hematopoietic subsets</a>
<div id="gene-popper8" class="gene-rif-popper">Title: Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins.</div>
</li>
</ol>
</div>
<div class="submit-genrif">
<span>Submit:</span>
<a href="/gene/submit-generif/?geneId=57826&amp;sym=RAP2C&amp;name=RAP2C, member of RAS oncogene family&amp;org=Homo sapiens">New GeneRIF</a>
<a href="/RefSeq/update.cgi?geneid=57826&amp;symbol=RAP2C;task=fixpub">Correction</a>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-phenotypes">
<section class="rprt-section-header" id="phenotypes">
<h2 id="header-phenotypes">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body info-phenotype">
<p class="nochild-link">
<a href="/gtr/tests/?term=RAP2C[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
</p>
<p class="nochild-link">
<a href="/gap/PheGenI?tab=1&amp;gene=57826">Review eQTL and phenotype association data in this region using PheGenI</a>
</p>
</div>
</div>
<div class="rprt-section gene-variation">
<section class="rprt-section-header" id="variation">
<h2 id="header-variation">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Variation</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p class="nochild-link">
<a href="/clinvar/?term=RAP2C[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
</p>
<p class="nochild-link">
<a href="/dbvar?LinkName=gene_dbvar&amp;from_uid=57826" ref="log$=recordlinks">See studies and variants in dbVar</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=57826[geneid]&amp;assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=57826[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
</p>
<set></set>
<set></set>
</div>
</div>
<div class="rprt-section gene-interactions">
<section class="rprt-section-header" id="interactions">
<h2 id="header-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/57826/data/interaction/',webserviceParams: 'p$l=Ajax&amp;p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th id="inter-prod">Products</th>
<th id="inter-interactant">Interactant</th>
<th id="inter-otherGene">Other Gene</th>
<th id="inter-compl">Complex</th>
<th id="inter-source">Source</th>
<th id="inter-pubs">Pubs</th>
<th id="inter-desc">Description</th>
</tr>
</thead>
<tbody></tbody>
</table>
</div>
</div>
<div class="rprt-section gene-general-gene-info">
<section class="rprt-section-header" id="general-gene-info">
<h2 id="header-general-gene-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General gene information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body" style="">
<div id="gene-markers">
<h3 id="markers">
<a class="jig-ncbitoggler">Markers</a>
</h3>
<div>
<ul class="marker odd">
<li class="marker">DXS7405 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=23684%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=23684">UniSTS:23684</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">RH94237 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=87254%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=87254">UniSTS:87254</a></li></ul></li>
</ul>
</div>
</div>
<div>
<div class="infosec" id="Relatedpseudogenes"><h3 id="relatedpseudogenes"><a class="jig-ncbitoggler-open">Related pseudogene(s)</a></h3>
<dl class="geneinfo-subsec"><dt>1 found
 
<a href="/gene/?Term=related_functional_gene_57826%5Bgroup%5D">Review record(s) in Gene</a></dt></dl>
</div>
</div>
<div class="infosec">
<h3 id="homology">
<a class="jig-ncbitoggler-open">Homology</a>
</h3>
<ul class="geneinfo-subsec">
<li>
<a href="/gene/57826/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
</li>
<a href="https://www.orthodb.org/?ncbi=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178" target="_blank">
Orthologs from OrthoDB
</a>
</ul>
</div>
<!--<component id="Gene_InfoPathway"/>-->
<div class="infosec info-comment" id="info-comment">
<h3 id="CloneNames">
<a class="jig-ncbitoggler-open">Clone Names</a>
</h3>
<ul class="geneinfo-subsec">
<li>DKFZp313B211 </li>
</ul>
</div>
<div class="gene-ontology infosec">
<h3 id="gene-ontology">
<a class="jig-ncbitoggler-open">
<span>Gene Ontology</span>
</a>
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
</h3>
<div class="ontology-tables">
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Function</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0003925">enables G protein activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-1-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0019003">enables GDP binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-2-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0019003">enables GDP binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-3-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/16213650" target="_blank" title="PubMed ID 16213650" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=16213650">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005525">enables GTP binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-4-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005525">enables GTP binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-5-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/16213650" target="_blank" title="PubMed ID 16213650" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=16213650">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0003924">enables GTPase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-6-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-7-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/23885123,32296183" target="_blank" title="PubMed ID 23885123,32296183" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=23885123,32296183">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0003713">enables transcription coactivator activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-8-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/17447155" target="_blank" title="PubMed ID 17447155" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=17447155">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Process</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0032486">involved_in Rap protein signal transduction</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-1-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0032486">involved_in Rap protein signal transduction</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-2-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0090557">involved_in establishment of endothelial intestinal barrier</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IGI</a>
<div id="evidence-code-3-1" class="ecode">Inferred from Genetic Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/23885123" target="_blank" title="PubMed ID 23885123" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=23885123">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0090557">involved_in establishment of endothelial intestinal barrier</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-4-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/23885123" target="_blank" title="PubMed ID 23885123" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=23885123">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030033">NOT involved_in microvillus assembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-5-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/22797597" target="_blank" title="PubMed ID 22797597" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=22797597">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030336">involved_in negative regulation of cell migration</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-6-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030336">involved_in negative regulation of cell migration</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-7-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0045893">involved_in positive regulation of DNA-templated transcription</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-8-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0061097">involved_in regulation of protein tyrosine kinase activity</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-9-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Component</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005923">located_in bicellular tight junction</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-1-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/23885123" target="_blank" title="PubMed ID 23885123" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=23885123">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0044291">located_in cell-cell contact zone</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/23885123" target="_blank" title="PubMed ID 23885123" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=23885123">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005737">located_in cytoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-3-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/17447155" target="_blank" title="PubMed ID 17447155" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=17447155">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-4-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0070062">located_in extracellular exosome</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> HDA</a>
<div id="evidence-code-5-2" class="ecode">
<br />
<a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a>
</div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/19056867,20458337" target="_blank" title="PubMed ID 19056867,20458337" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=19056867,20458337">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">is_active_in plasma membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-6-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-7-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/16213650" target="_blank" title="PubMed ID 16213650" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=16213650">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-8-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0055038">located_in recycling endosome membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-9-2" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0070821">located_in tertiary granule membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-10-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-general-protein-info">
<section class="rprt-section-header" id="general-protein-info">
<h2 id="header-general-protein-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General protein information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<dl>
<dt>Preferred Names</dt>
<dd>ras-related protein Rap-2c</dd>
</dl>
<dl>
<dt>Names</dt>
<dd>small GTPase RAP2C</dd>
</dl>
<dl>
<dt class="heading">NP_001258115.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001258116.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_067006.3</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_006724838.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011529678.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047298245.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047298246.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054183440.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054183441.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054183442.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054183443.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/3.6.5.2">3.6.5.2</a></li>
</ul>
</dd>
</dl>
</div>
</div>
<div class="rprt-section gene-reference-sequences">
<section class="rprt-section-header" id="reference-sequences">
<h2 id="header-reference-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p>
<span class="new-icon">NEW</span>
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&amp;ids=57826&amp;utm_source=gene&amp;utm_medium=referral&amp;utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
</p>
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
Genomes</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
<p id="refseq-expl"> These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
transcripts, and products</a> above. </p>
<h4 id="mrnaandproteins-p114947584">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/NM_001271186.2">NM_001271186.2</a><a href="/protein/NP_001258115.1">NP_001258115.1</a>  ras-related protein Rap-2c isoform 1 precursor</p>
<p>
<a href="/ipg/NP_001258115.1/" ref="ncbi_uid=57826">See identical proteins and their annotated locations for NP_001258115.1</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Description</dt>
<dd>Transcript Variant: This variant (1) represents the longest transcript. Both variants 1 and 2 encode the same isoform (1).</dd>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AY298955, BC035382, BX399437, DB252216">AY298955, BC035382, BX399437, DB252216</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS14632.1">CCDS14632.1</a>
</dd>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B3KWD6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">B3KWD6</a>, <a href="https://www.uniprot.org/uniprot/Q5H9H9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q5H9H9</a>, <a href="https://www.uniprot.org/uniprot/Q9BTS0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9BTS0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y3L5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9Y3L5</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000359911.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">ENSP00000359911.1</a>, <a href="http://www.ensembl.org/id/ENST00000370874.2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">ENST00000370874.2</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001258115.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=133376">cd04176</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">3</span><span class="cddto">165</span></dt>
<dd class="clearfix"> Rap2; Rap2 family GTPase consists of Rap2a, Rap2b, and Rap2c</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001271187.2">NM_001271187.2</a><a href="/protein/NP_001258116.1">NP_001258116.1</a>  ras-related protein Rap-2c isoform 2</p>
<p>
<a href="/ipg/NP_001258116.1/" ref="ncbi_uid=57826">See identical proteins and their annotated locations for NP_001258116.1</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Description</dt>
<dd>Transcript Variant: This variant (3) uses an alternate 5' structure, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.</dd>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AK310997, AY298955, BI767215, CN308919">AK310997, AY298955, BI767215, CN308919</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS76024.1">CCDS76024.1</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A087X2C3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">A0A087X2C3</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000484870.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">ENSP00000484870.1</a>, <a href="http://www.ensembl.org/id/ENST00000620646.4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">ENST00000620646.4</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001258116.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=422963">cl38936</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">99</span></dt>
<dd class="clearfix"> P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_021183.5">NM_021183.5</a><a href="/protein/NP_067006.3">NP_067006.3</a>  ras-related protein Rap-2c isoform 1 precursor</p>
<p>
<a href="/ipg/NP_067006.3/" ref="ncbi_uid=57826">See identical proteins and their annotated locations for NP_067006.3</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Description</dt>
<dd>Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1).</dd>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AY298955">AY298955</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS14632.1">CCDS14632.1</a>
</dd>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B3KWD6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">B3KWD6</a>, <a href="https://www.uniprot.org/uniprot/Q5H9H9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q5H9H9</a>, <a href="https://www.uniprot.org/uniprot/Q9BTS0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9BTS0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y3L5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9Y3L5</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000340274.2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">ENSP00000340274.2</a>, <a href="http://www.ensembl.org/id/ENST00000342983.6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">ENST00000342983.6</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_067006.3">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=133376">cd04176</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">3</span><span class="cddto">165</span></dt>
<dd class="clearfix"> Rap2; Rap2 family GTPase consists of Rap2a, Rap2b, and Rap2c</dd>
</dl>
</dd>
</dl>
</li>
</ol>
<h4 id="rna-p4888800">RNA</h4>
<ol>
<li>
<p><a href="/nuccore/NR_073150.2">NR_073150.2</a> RNA Sequence </p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Description</dt>
<dd>Transcript Variant: This variant (4) uses an alternate 5' exon structure, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region found in variant 1.</dd>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AK310997, AY298955, BI767215">AK310997, AY298955, BI767215</a>
</dd>
</dl>
</li>
</ol>
</div>
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> The following sections contain reference sequences that belong to a
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.</p>
<h3 id="refseq-sequencedescription-p59777504">Reference GRCh38.p14 Primary Assembly</h3>
<h4 id="genomic-p59777504">Genomic </h4>
<ol>
<li>
<p>NC_000023.11 Reference GRCh38.p14 Primary Assembly</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>132203025..132219447 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_000023.11?from=132203025&amp;to=132219447&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_000023.11?from=132203025&amp;to=132219447&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_000023.11?from=132203025&amp;to=132219447&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_000023.11?from=132203025&amp;to=132219447&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_000023.11?from=132200561&amp;to=132221909&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_000023.11?from=132200561&amp;to=132221909&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p119460352">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_047442289.1">XM_047442289.1</a><a href="/protein/XP_047298245.1">XP_047298245.1</a>  ras-related protein Rap-2c isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B3KWD6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">B3KWD6</a>, <a href="https://www.uniprot.org/uniprot/Q5H9H9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q5H9H9</a>, <a href="https://www.uniprot.org/uniprot/Q9BTS0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9BTS0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y3L5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9Y3L5</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011531376.2">XM_011531376.2</a><a href="/protein/XP_011529678.1">XP_011529678.1</a>  ras-related protein Rap-2c isoform X1</p>
<p>
<a href="/ipg/XP_011529678.1/" ref="ncbi_uid=57826">See identical proteins and their annotated locations for XP_011529678.1</a>
</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B3KWD6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">B3KWD6</a>, <a href="https://www.uniprot.org/uniprot/Q5H9H9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q5H9H9</a>, <a href="https://www.uniprot.org/uniprot/Q9BTS0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9BTS0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y3L5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9Y3L5</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011529678.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=133376">cd04176</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">3</span><span class="cddto">165</span></dt>
<dd class="clearfix"> Rap2; Rap2 family GTPase consists of Rap2a, Rap2b, and Rap2c</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_006724775.3">XM_006724775.3</a><a href="/protein/XP_006724838.1">XP_006724838.1</a>  ras-related protein Rap-2c isoform X2</p>
<p>
<a href="/ipg/XP_006724838.1/" ref="ncbi_uid=57826">See identical proteins and their annotated locations for XP_006724838.1</a>
</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A087X2C3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">A0A087X2C3</a>
</dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_006724838.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=422963">cl38936</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">99</span></dt>
<dd class="clearfix"> P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047442290.1">XM_047442290.1</a><a href="/protein/XP_047298246.1">XP_047298246.1</a>  ras-related protein Rap-2c isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B3KWD6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">B3KWD6</a>, <a href="https://www.uniprot.org/uniprot/Q5H9H9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q5H9H9</a>, <a href="https://www.uniprot.org/uniprot/Q9BTS0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9BTS0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y3L5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9Y3L5</a></dd>
</dl>
</li>
</ol>
<h4 id="rna-p99950864">RNA</h4>
<ol>
<li>
<p><a href="/nuccore/XR_430548.2">XR_430548.2</a> RNA Sequence </p>
<dl></dl>
</li>
</ol>
<h3 id="refseq-sequencedescription-p86154080">Alternate T2T-CHM13v2.0</h3>
<h4 id="genomic-p86154080">Genomic </h4>
<ol>
<li>
<p>NC_060947.1 Alternate T2T-CHM13v2.0</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>130527262..130543665 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_060947.1?from=130527262&amp;to=130543665&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_060947.1?from=130527262&amp;to=130543665&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_060947.1?from=130527262&amp;to=130543665&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_060947.1?from=130527262&amp;to=130543665&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_060947.1?from=130524801&amp;to=130546124&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=NC_060947.1?from=130524801&amp;to=130546124&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p94810880">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_054327465.1">XM_054327465.1</a><a href="/protein/XP_054183440.1">XP_054183440.1</a>  ras-related protein Rap-2c isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B3KWD6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">B3KWD6</a>, <a href="https://www.uniprot.org/uniprot/Q5H9H9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q5H9H9</a>, <a href="https://www.uniprot.org/uniprot/Q9BTS0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9BTS0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y3L5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9Y3L5</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054327466.1">XM_054327466.1</a><a href="/protein/XP_054183441.1">XP_054183441.1</a>  ras-related protein Rap-2c isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B3KWD6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">B3KWD6</a>, <a href="https://www.uniprot.org/uniprot/Q5H9H9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q5H9H9</a>, <a href="https://www.uniprot.org/uniprot/Q9BTS0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9BTS0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y3L5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9Y3L5</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054327468.1">XM_054327468.1</a><a href="/protein/XP_054183443.1">XP_054183443.1</a>  ras-related protein Rap-2c isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A087X2C3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">A0A087X2C3</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054327467.1">XM_054327467.1</a><a href="/protein/XP_054183442.1">XP_054183442.1</a>  ras-related protein Rap-2c isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B3KWD6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">B3KWD6</a>, <a href="https://www.uniprot.org/uniprot/Q5H9H9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q5H9H9</a>, <a href="https://www.uniprot.org/uniprot/Q9BTS0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9BTS0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y3L5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=57826&amp;nlmid=&amp;db=gene">Q9Y3L5</a></dd>
</dl>
</li>
</ol>
<h4 id="rna-p105381968">RNA</h4>
<ol>
<li>
<p><a href="/nuccore/XR_008485503.1">XR_008485503.1</a> RNA Sequence </p>
<dl></dl>
</li>
</ol>
</div>
</div>
</div>
<div class="rprt-section gene-related-sequences">
<section class="rprt-section-header" id="related-sequences">
<h2 id="header-related-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Related sequences</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/57826/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th colspan="2" id="rs-nucleo">Nucleotide</th>
<th rowspan="2" id="rs-protein">Protein</th>
</tr>
<tr>
<th id="rs-heading">Heading</th>
<th id="rs-heading-acc">Accession and Version</th>
</tr>
</thead>
<tbody></tbody>
</table>
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
<thead>
<tr>
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
</tr>
<tr>
<th id="rs-genepept">GenPept Link</th>
<th id="rs-uniprot">UniProtKB Link</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="rs-prot-acc">Q9Y3L5.1</td>
<td headers="rs-link rs-genepept">
<a href="/protein/47117343" ref="ordinalpos=1&amp;ncbi_uid=57826&amp;link_uid=47117343">GenPept</a>
</td>
<td>
<a href="https://www.uniprot.org/uniprot/Q9Y3L5">UniProtKB/Swiss-Prot:Q9Y3L5</a>
</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-additional-links">
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
<div class="rprt-section-body" style="">
<h3 class="withnote" id="genelinkout">
<a class="jig-ncbitoggler">Gene LinkOut</a>
</h3><div>
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
<div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Chemical Information</span>
</a>
<ul>
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
<ul>
<li>
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7911">
<span>Interologous Interaction Database</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>MilliporeSigma</li>
<ul>
<li>
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/RAP2C?lang=en&amp;region=US" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9978">
<span>Rap2c products</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Molecular Biology Databases</span>
</a>
<ul>
<li><span class="free-rsc"></span>Bgee database</li>
<ul>
<li>
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000123728" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10418">
<span>RAP2C gene expression</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGPS</li>
<ul>
<li>
<a target="_blank" href="http://biogps.org/gene/57826/" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5059">
<span>BioGPS</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
<ul>
<li>
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10164">
<span>BioGRID CRISPR Screen Phenotypes (19 hits/989 screens)</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>CTD: Comparative Toxicogenomics Database</li>
<ul>
<li>
<a target="_blank" href="http://ctdbase.org/detail.go?type=gene&amp;acc=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7845">
<span>CTD: Comparative Toxicogenomics Database - RAP2C</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
<ul>
<li>
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7642">
<span>RAP2C</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
<ul>
<li>
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&amp;format=genome&amp;entry=RAP2C_1" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9624">
<span>RAP2C_1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
<ul>
<li>
<a target="_blank" href="https://glygen.org/protein/Q9Y3L5" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10227">
<span>GlyGen glycoinformatics resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Human eFP Browser</li>
<ul>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&amp;modeInput=Absolute&amp;primaryGene=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&amp;modeInput=Absolute&amp;primaryGene=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Nervous&amp;modeInput=Absolute&amp;primaryGene=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
</ul>
<li>Ingenuity Pathways Analysis</li>
<ul>
<li>
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&amp;p1=Entrez&amp;p2=GV&amp;s=&amp;ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D57826%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5628">
<span>Ingenuity Pathways Analysis</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InnateDB</li>
<ul>
<li>
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=86513" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7894">
<span>InnateDB</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InterMine</li>
<ul>
<li>
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000123728" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9169">
<span>InterMine</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
<ul>
<li>
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5174">
<span>Kyoto Encyclopedia of Genes and Genomes</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
<ul>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN102197/" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN102199/" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN102198/" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
<ul>
<li>
<a target="_blank" href="https://www.orthodb.org/?ncbi=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178">
<span>Orthologs</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
<ul>
<li>
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7987">
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
<ul>
<li>
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=RAP2C" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8598">
<span>GeneCard for RAP2C</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Research Materials</span>
</a>
<ul>
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
<ul>
<li>
<a target="_blank" href="https://addgene.org//browse/gene/57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5304">
<span>Get Plasmids - Addgene</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Bio-Techne</li>
<ul>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/rap2c/lysates?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=lysates" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>RAP2C Lysates</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/rap2c/proteins-enzymes?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=proteins" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>RAP2C Proteins</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/rap2c/antibodies?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=antibodies" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>RAP2C Antibodies</span>
</a>
</li>
</ul>
<li>ExactAntigen/Labome</li>
<ul>
<li>
<a target="_blank" href="https://www.labome.com/gene/human/RAP2C-antibody.html" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagents</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
<ul>
<li>
<a target="_blank" href="http://www.genscript.com/gene/57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8012">
<span>GenScript latest version of gene cDNA ORF Clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
<ul>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=26&amp;field=5&amp;key=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order TALEN/CRISPR clones</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&amp;field=5&amp;prt=16&amp;key=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order miRNA target clones</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&amp;field=5&amp;key=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order full-length ORF clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneTex Inc</li>
<ul>
<li>
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=57826&amp;type=01&amp;page=1" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8117">
<span>Find Quality Antibodies</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=57826&amp;type=03&amp;page=1" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8117">
<span>Find Recombinant Proteins and Peptides</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>OriGene</li>
<ul>
<li>
<a target="_blank" href="https://www.origene.com/search?q=RAP2C" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7994">
<span>Order RAP2C cDNA clone/Protein/Antibody/RNAi</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Tools</span>
</a>
<ul>
<li><span class="free-rsc"></span>GeneMANIA</li>
<ul>
<li>
<a target="_blank" href="http://genemania.org/link?o=9606&amp;g=57826" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7529">
<span>GeneMANIA</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open">
<span>Miscellaneous</span>
</a>
<ul>
<li><span class="free-rsc"></span>Reactome</li>
<ul>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-168256" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Immune System</span>
</a>
</li>
<li>
<a target="_blank" href="https://reactome.org/content/query?q=UniProt:Q9Y3L5" ref="itool=Gene_FullReport&amp;uid=57826&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Entity:Q9Y3L5</span>
</a>
</li>
</ul>
</ul>
</div>
</div>
</div>
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</div>
</div>
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</div>
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</div>
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<!-- sidebar close/hide button-->
<div class="ui-helper-clearfix">
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<h2 class="offscreen_noflow">Supplemental Content</h2>
<div id="gene-sidebar">
<div>
<div class="portlet brieflink dis-table-of-contents">
<div class="portlet_head">
<div class="portlet_title">
<h3>Table of contents</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li class="">
<a href="#summary">Summary</a>
</li>
<li class="">
<a href="#genomic-context">Genomic context</a>
</li>
<li class="">
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
</li>
<li class="">
<a href="#gene-expression">Expression</a>
</li>
<li class="">
<a href="#bibliography">Bibliography</a>
</li>
<li class="">
<a href="#phenotypes">Phenotypes</a>
</li>
<li class="">
<a href="#variation">Variation</a>
</li>
<li class="">
<a href="#interactions">Interactions</a>
</li>
<li class="">
<a href="#general-gene-info">General gene information</a>
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#Relatedpseudogenes">Related pseudogene(s)</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
</li>
<li class="">
<a href="#general-protein-info">General protein information</a>
</li>
<li class="">
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
</li>
<li class="">
<a href="#related-sequences">Related sequences</a>
</li>
<li class="">
<a href="#additional-links">Additional links</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
<div class="portlet_head">
<div class="portlet_title">
<h3>Genome Browsers</h3>
</div>
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<li>
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</li>
</ul>
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<div class="portlet dis-related-info brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related information</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
</div>
<div class="portlet_content DiscoveryDbLinks">
<ul>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clone/order/gene/57826" ref="log$=recordlinks">Order cDNA clone</a>
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&amp;from_uid=57826" ref="log$=recordlinks">BioAssay by Target (List)</a>
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&amp;from_uid=57826" ref="log$=recordlinks">BioAssay, by Gene target</a>
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&amp;from_uid=57826" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&amp;from_uid=57826" ref="log$=recordlinks">BioProjects</a>
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&amp;from_uid=57826" ref="log$=recordlinks">BioSystems</a>
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&amp;DATA=57826" ref="log$=recordlinks">CCDS</a>
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&amp;from_uid=57826" ref="log$=recordlinks">ClinVar</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&amp;from_uid=57826" ref="log$=recordlinks">Conserved Domains</a>
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&amp;from_uid=57826" ref="log$=recordlinks">dbVar</a>
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&amp;from_uid=57826" ref="log$=recordlinks">Full text in PMC</a>
<div class="brieflinkpop offscreen_noflow">PMC links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&amp;from_uid=57826" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&amp;from_uid=57826" ref="log$=recordlinks">Functional Class</a>
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gap?LinkName=gene_gap&amp;from_uid=57826" ref="log$=recordlinks">GAP</a>
<div class="brieflinkpop offscreen_noflow">GAP Links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&amp;from_uid=57826" ref="log$=recordlinks">Gene neighbors</a>
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&amp;from_uid=57826" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&amp;from_uid=57826" ref="log$=recordlinks">Genome</a>
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&amp;from_uid=57826" ref="log$=recordlinks">GEO Profiles</a>
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=57826[geneid]" ref="log$=recordlinks">GTR</a>
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&amp;from_uid=57826" ref="log$=recordlinks">HomoloGene</a>
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&amp;from_uid=57826" ref="log$=recordlinks">Nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&amp;from_uid=57826" ref="log$=recordlinks">OMIM</a>
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&amp;from_uid=57826" ref="log$=recordlinks">Probe</a>
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&amp;from_uid=57826" ref="log$=recordlinks">Protein</a>
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&amp;from_uid=57826" ref="log$=recordlinks">PubChem Compound</a>
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&amp;from_uid=57826" ref="log$=recordlinks">PubChem Substance</a>
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&amp;from_uid=57826" ref="log$=recordlinks">PubMed</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&amp;from_uid=57826" ref="log$=recordlinks">PubMed (GeneRIF)</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&amp;from_uid=57826" ref="log$=recordlinks">PubMed (OMIM)</a>
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&amp;from_uid=57826" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&amp;from_uid=57826" ref="log$=recordlinks">RefSeq Proteins</a>
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&amp;from_uid=57826" ref="log$=recordlinks">RefSeq RNAs</a>
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&amp;from_uid=57826" ref="log$=recordlinks">SNP</a>
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&amp;from_uid=57826" ref="log$=recordlinks">Taxonomy</a>
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/variation/view/?q=57826[geneid]" ref="log$=recordlinks">Variation Viewer</a>
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
</li>
</ul>
</div>
</div>
<div class="portlet dis-links-to-other-res brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Links to other resources</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:21165">HGNC</a>
</li>
<li>
<a href="http://www.ensembl.org/id/ENSG00000123728">Ensembl</a>
</li>
<li>
<a href="https://www.alliancegenome.org/gene/HGNC:21165">AllianceGenome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&amp;org=9606&amp;l=57826">AceView</a>
</li>
<li>
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&amp;position=NM_001271186">UCSC</a>
</li>
<li>
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&amp;LIST=BC003403">MGC</a>
</li>
<li>
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:57826">KEGG</a>
</li>
<li>
<a href="https://reactome.org/content/query?q=UniProt:Q9Y3L5">Reactome</a>
</li>
</ul>
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