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To:
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From:
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Format:
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<h3 class="action-panel-heading">
Add to Collections
</h3>
<form id="collections-action-panel-form"
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<ul class="radio-group-items">
<li>
<input type="radio"
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value="new"
data-ga-category="save_share"
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Name your collection:
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Choose a collection:
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aria-hidden="true"
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Add to My Bibliography
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Your saved search
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Name of saved search:
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Search terms:
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<textarea name="saved-search-term" id="saved-search-term" class="saved-search-term" required></textarea>
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<a href="#" class="try-search-term">Test search terms</a>
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<span class="action-panel-label" id="fieldset-label">
Would you like email updates of new search results?
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<div class="action-panel-control-wrap">
<label class="action-panel-label">
Email:
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<span aria-label="Email address" id="saved-search-email" class="action-panel-label"><span class="action-panel-label-bold"></span> (<a class="myncbi-account-settings" href="https://www.ncbi.nlm.nih.gov/account/settings/">change</a>)</span>
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Which day?
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Which day?
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Report format:
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Send at most:
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<button class="action-panel-submit"
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Create file
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<button class="action-panel-cancel"
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ref="linksrc=close_citation_manager_panel"
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Cancel
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<div id="rss-action-panel" class="rss-action-panel action-panel " aria-hidden="true">
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<h2 class="action-panel-heading">
Your RSS Feed
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data-ga-category="save_share"
data-ga-action="alert"
data-ga-label="save">
Create RSS
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ref="linksrc=close_rss_panel"
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Copy
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<h1 class="heading-title">
Large recurrent microdeletions associated with schizophrenia
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data-ga-label="Engilbert Sigurdsson">Engilbert Sigurdsson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Sigmundsson+T&amp;cauthor_id=18668039"
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data-ga-action="author_link"
data-ga-label="Thordur Sigmundsson">Thordur Sigmundsson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Buizer-Voskamp+JE&amp;cauthor_id=18668039"
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data-ga-label="Jacobine E Buizer-Voskamp">Jacobine E Buizer-Voskamp</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Hansen+T&amp;cauthor_id=18668039"
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data-ga-label="Thomas Hansen">Thomas Hansen</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Jakobsen+KD&amp;cauthor_id=18668039"
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data-ga-label="Klaus D Jakobsen">Klaus D Jakobsen</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Muglia+P&amp;cauthor_id=18668039"
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data-ga-label="Pierandrea Muglia">Pierandrea Muglia</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Francks+C&amp;cauthor_id=18668039"
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data-ga-action="author_link"
data-ga-label="Clyde Francks">Clyde Francks</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Matthews+PM&amp;cauthor_id=18668039"
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data-ga-action="author_link"
data-ga-label="Paul M Matthews">Paul M Matthews</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Gylfason+A&amp;cauthor_id=18668039"
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data-ga-label="Arnaldur Gylfason">Arnaldur Gylfason</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Halldorsson+BV&amp;cauthor_id=18668039"
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data-ga-label="Bjarni V Halldorsson">Bjarni V Halldorsson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Gudbjartsson+D&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Daniel Gudbjartsson">Daniel Gudbjartsson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Thorgeirsson+TE&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-label="Thorgeir E Thorgeirsson">Thorgeir E Thorgeirsson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Sigurdsson+A&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Asgeir Sigurdsson">Asgeir Sigurdsson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Jonasdottir+A&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Adalbjorg Jonasdottir">Adalbjorg Jonasdottir</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Jonasdottir+A&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Aslaug Jonasdottir">Aslaug Jonasdottir</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Bjornsson+A&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Asgeir Bjornsson">Asgeir Bjornsson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Mattiasdottir+S&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Sigurborg Mattiasdottir">Sigurborg Mattiasdottir</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Blondal+T&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Thorarinn Blondal">Thorarinn Blondal</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Haraldsson+M&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Magnus Haraldsson">Magnus Haraldsson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Magnusdottir+BB&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Brynja B Magnusdottir">Brynja B Magnusdottir</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Giegling+I&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Ina Giegling">Ina Giegling</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=M%C3%B6ller+HJ&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Hans-Jürgen Möller">Hans-Jürgen Möller</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Hartmann+A&amp;cauthor_id=18668039"
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data-ga-action="author_link"
data-ga-label="Annette Hartmann">Annette Hartmann</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Shianna+KV&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Kevin V Shianna">Kevin V Shianna</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Ge+D&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Dongliang Ge">Dongliang Ge</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Need+AC&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Anna C Need">Anna C Need</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Crombie+C&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
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data-ga-action="author_link"
data-ga-label="Caroline Crombie">Caroline Crombie</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Fraser+G&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Gillian Fraser">Gillian Fraser</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Walker+N&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Nicholas Walker">Nicholas Walker</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Lonnqvist+J&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Jouko Lonnqvist">Jouko Lonnqvist</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Suvisaari+J&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Jaana Suvisaari">Jaana Suvisaari</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Tuulio-Henriksson+A&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Annamarie Tuulio-Henriksson">Annamarie Tuulio-Henriksson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Paunio+T&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Tiina Paunio">Tiina Paunio</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Toulopoulou+T&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Timi Toulopoulou">Timi Toulopoulou</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Bramon+E&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Elvira Bramon">Elvira Bramon</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Di+Forti+M&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Marta Di Forti">Marta Di Forti</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Murray+R&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Robin Murray">Robin Murray</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Ruggeri+M&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Mirella Ruggeri">Mirella Ruggeri</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Vassos+E&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Evangelos Vassos">Evangelos Vassos</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Tosato+S&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Sarah Tosato">Sarah Tosato</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Walshe+M&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Muriel Walshe">Muriel Walshe</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Li+T&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Tao Li">Tao Li</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Vasilescu+C&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Catalina Vasilescu">Catalina Vasilescu</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=M%C3%BChleisen+TW&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Thomas W Mühleisen">Thomas W Mühleisen</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Wang+AG&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="August G Wang">August G Wang</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Ullum+H&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Henrik Ullum">Henrik Ullum</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Djurovic+S&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Srdjan Djurovic">Srdjan Djurovic</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Melle+I&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Ingrid Melle">Ingrid Melle</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Olesen+J&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Jes Olesen">Jes Olesen</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Kiemeney+LA&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Lambertus A Kiemeney">Lambertus A Kiemeney</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Franke+B&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Barbara Franke">Barbara Franke</a><span class="semicolon">;&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=GROUP%5BCorporate+Author%5D"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="GROUP">GROUP</a><span class="semicolon">;&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Sabatti+C&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Chiara Sabatti">Chiara Sabatti</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Freimer+NB&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Nelson B Freimer">Nelson B Freimer</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Gulcher+JR&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Jeffrey R Gulcher">Jeffrey R Gulcher</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Thorsteinsdottir+U&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Unnur Thorsteinsdottir">Unnur Thorsteinsdottir</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Kong+A&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Augustine Kong">Augustine Kong</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Andreassen+OA&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Ole A Andreassen">Ole A Andreassen</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Ophoff+RA&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Roel A Ophoff">Roel A Ophoff</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Georgi+A&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Alexander Georgi">Alexander Georgi</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Rietschel+M&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Marcella Rietschel">Marcella Rietschel</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Werge+T&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Thomas Werge">Thomas Werge</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Petursson+H&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Hannes Petursson">Hannes Petursson</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Goldstein+DB&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="David B Goldstein">David B Goldstein</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=N%C3%B6then+MM&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Markus M Nöthen">Markus M Nöthen</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Peltonen+L&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Leena Peltonen">Leena Peltonen</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Collier+DA&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="David A Collier">David A Collier</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=St+Clair+D&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="David St Clair">David St Clair</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Stefansson+K&amp;cauthor_id=18668039"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Kari Stefansson">Kari Stefansson</a></span>
</div>
</div>
<div class="collaborations">
<h3 class="title">
Collaborators
</h3>
<ul class="group-list">
<li>
<strong class="title">GROUP</strong>:
<div class="authors-list">
<span class="authors-list-item "><a class="full-name"
href="/?term=Kahn+RS"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="René S Kahn">René S Kahn</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Linszen+DH"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Don H Linszen">Don H Linszen</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=van+Os+J"
ref="linksrc=author_name_link"
data-ga-category="search"
data-ga-action="author_link"
data-ga-label="Jim van Os">Jim van Os</a><span class="comma">,&nbsp;</span></span><span class="authors-list-item "><a class="full-name"
href="/?term=Wiersma+D"
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Reduced fecundity, associated with severe mental disorders, places negative selection pressure on risk alleles and may explain, in part, why common variants have not been found that confer risk of disorders such as autism, schizophrenia and mental retardation. Thus, rare variants may account for a larger fraction of the overall genetic risk than previously assumed. In contrast to rare single nucleotide mutations, rare copy number variations (CNVs) can be detected using genome-wide single nucleotide polymorphism arrays. This has led to the identification of CNVs associated with mental retardation and autism. In a genome-wide search for CNVs associating with schizophrenia, we used a population-based sample to identify de novo CNVs by analysing 9,878 transmissions from parents to offspring. The 66 de novo CNVs identified were tested for association in a sample of 1,433 schizophrenia cases and 33,250 controls. Three deletions at 1q21.1, 15q11.2 and 15q13.3 showing nominal association with schizophrenia in the first sample (phase I) were followed up in a second sample of 3,285 cases and 7,951 controls (phase II). All three deletions significantly associate with schizophrenia and related psychoses in the combined sample. The identification of these rare, recurrent risk variants, having occurred independently in multiple founders and being subject to negative selection, is important in itself. CNV analysis may also point the way to the identification of additional and more prevalent risk variants in genes and pathways involved in schizophrenia.
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<p> Figure 1. The genomic architecture of the 1q21.1, 15q11.2 and 15q13.3 deletions </p>
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Figure 1. The genomic architecture of the 1q21.1, 15q11.2 and 15q13.3 deletions
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<div class="figure-caption-contents"><b>a,</b> DosageMiner output showing the shorter form of the 1q21 deletion (marked in blue). Ninety-nine SNPs on the HumanHap300 chip are affected by the deletion which spans 1.38 Mb. <b>b,</b> DosageMiner output showing the 15q11.2 deletion (marked in blue). Fifty-four SNPs on the HumanHap300 chip are affected by the deletion which spans 470 kb. <b>c,</b> DosageMiner output showing the 15q13.3 deletion (marked in blue). One-hundred-and-sixty-six SNPs on the HumanHap300 chip are affected by the deletion which spans 1.57 Mb. Genes affected by the deletions are shown (coordinates are based on Build 36 of the human genome and positions of genes derived from the UCSC genome browser). LCRs flank all three deletions (Supplementary Figs 1, 3 and 4).</div>
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<span class="docsum-journal-citation full-journal-citation">ACS Synth Biol. 2024 Oct 18;13(10):3212-3230. doi: 10.1021/acssynbio.4c00271. Epub 2024 Oct 8.</span>
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<span class="docsum-journal-citation full-journal-citation">Harv Rev Psychiatry. 2015 Jan-Feb;23(1):1-18. doi: 10.1097/HRP.0000000000000054.</span>
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