87 lines
52 KiB
HTML
87 lines
52 KiB
HTML
<!DOCTYPE html>
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<html amp lang="en-US" data-amp-auto-lightbox-disable transformed="self;v=1" i-amphtml-layout="" i-amphtml-no-boilerplate="">
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/*# sourceURL=/css/ampshared.css*/</style><meta property="og:locale" content="en_US"><meta property="og:type" content="article"><meta property="og:title" content="Open Access! Million Veteran Program Genome-Wide PheWAS Results Now Available in dbGaP! - NCBI Insights"><meta property="og:description" content="The Million Veteran Program (MVP) is a research program from the U.S. Department of Veterans Affairs (VA) that has collected and analyzed health information from over one million veteran volunteers. The data include genes, lifestyles, military experiences, and exposures that may impact health and wellness. The results of the MVP phenome-wide association study (PheWAS) … Continue reading Open Access! Million Veteran Program Genome-Wide PheWAS Results Now Available in dbGaP! →"><meta property="og:url" content="https://ncbiinsights.ncbi.nlm.nih.gov/2024/07/22/million-veteran-program-dbgap/"><meta property="og:site_name" content="NCBI Insights"><meta property="article:publisher" content="https://www.facebook.com/ncbi.nlm"><meta property="article:published_time" content="2024-07-22T14:33:05+00:00"><meta property="og:image" content="https://ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2024/07/dbGaP_MVP_Data-3-e1721316024373.png"><meta property="og:image:width" content="1100"><meta property="og:image:height" content="575"><meta property="og:image:type" content="image/png"><meta name="author" content="NCBI Staff"><meta name="twitter:card" content="summary_large_image"><meta name="twitter:creator" content="@NCBI"><meta name="twitter:site" content="@NCBI"><meta name="twitter:label1" content="Written by"><meta name="twitter:data1" content="NCBI Staff"><meta name="twitter:label2" 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Million Veteran Program Genome-Wide PheWAS Results Now Available in dbGaP! - NCBI Insights</title></head>
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<h1 class="amp-wp-title">Open Access! Million Veteran Program Genome-Wide PheWAS Results Now Available in dbGaP!</h1>
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<time datetime="2024-07-22T14:33:05+00:00">
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8 months ago </time>
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<amp-img width="1024" height="535" src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2024/07/dbGaP_MVP_Data-3-e1721316024373.png?fit=1024%2C535&ssl=1" class="attachment-large size-large wp-post-image amp-wp-enforced-sizes i-amphtml-layout-intrinsic i-amphtml-layout-size-defined" alt="Image of American Army soldiers marching in the background. Text says: Open Access! dbGaP Database of Genotypes and Phenotypes Million Veterans Program PheWas data now available!" data-hero-candidate="" layout="intrinsic" data-hero i-amphtml-ssr i-amphtml-layout="intrinsic"><i-amphtml-sizer slot="i-amphtml-svc" class="i-amphtml-sizer"><img alt="" aria-hidden="true" class="i-amphtml-intrinsic-sizer" role="presentation" src="data:image/svg+xml;base64,PHN2ZyBoZWlnaHQ9IjUzNSIgd2lkdGg9IjEwMjQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyIgdmVyc2lvbj0iMS4xIi8+"></i-amphtml-sizer><img class="i-amphtml-fill-content i-amphtml-replaced-content" decoding="async" loading="lazy" alt="Image of American Army soldiers marching in the background. Text says: Open Access! dbGaP Database of Genotypes and Phenotypes Million Veterans Program PheWas data now available!" src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2024/07/dbGaP_MVP_Data-3-e1721316024373.png?fit=1024%2C535&ssl=1"></amp-img> </figure>
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<p><span data-contrast="none">The </span><a href="https://www.mvp.va.gov/pwa/"><span data-contrast="none">Million Veteran Program (MVP)</span></a><span data-contrast="none"> is a research program from the U.S. Department of Veterans Affairs (VA) that has collected and analyzed health information from over one million veteran volunteers. The data include genes, lifestyles, military experiences, and exposures that may impact health and wellness. </span><span data-ccp-props='{"134233117":true,"134233118":true,"201341983":0,"335557856":16777215,"335559739":160,"335559740":240}'> </span></p>
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<p><span data-contrast="none">The results of the MVP phenome-wide association study (PheWAS) analysis are now available in NLM-NCBI’s </span><a href="https://www.ncbi.nlm.nih.gov/gap/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=dbgap-million-veterans-20240722"><span data-contrast="none">database of Genotypes and Phenotypes (dbGaP)</span></a><span data-contrast="none">. The PheWAS summary data is based on information from approximately 600,000 veterans from four broad ancestry groups, with hundreds of phenotypic traits recorded in medical records. This is one of the largest publicly available PheWAS datasets to date and does not require an application to access the data. </span><span data-ccp-props='{"134233117":true,"134233118":true,"201341983":0,"335557856":16777215,"335559739":160,"335559740":240}'> </span></p>
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<p><span data-contrast="none">You will be able to learn about the available data in <a href="https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002453.v1.p1">dbGaP</a> and download the full summary dataset from the <a href="https://ftp.ncbi.nlm.nih.gov/dbgap/studies/phs002453">FTP site</a>. We have also included the “top hits” (lowest p-values) for further exploration in two visualization tools with specialty tracks in the </span><a href="https://www.ncbi.nlm.nih.gov/gdv/browser/dbgap-gwas/?id=pha005146&chr=9&from=9389138&to=138394718"><span data-contrast="none">Genome Data Viewer (GDV)</span></a><span data-contrast="auto"> and the new </span><a href="https://www.ncbi.nlm.nih.gov/gdv/gwas/5146/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=dbgap-million-veterans-20240722"><span data-contrast="none">Genomic Analysis Navigator</span></a><span data-contrast="auto">.</span><span data-ccp-props='{"134233117":true,"134233118":true,"201341983":0,"335557856":16777215,"335559739":160,"335559740":240}'> </span></p>
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<h5>Learn more</h5>
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<p><span data-contrast="none">Read the VA’s <a href="https://news.va.gov/133297/new-mvp-study-highlights-value-of-diversity-in-clinical-research-leads-to-new-genetic-discoveries/">recent announcement</a> on the new MVP analysis to learn more!</span><span data-ccp-props='{"134233117":true,"134233118":true,"201341983":0,"335557856":16777215,"335559739":160,"335559740":240}'> </span></p>
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<p><span data-contrast="none">Follow us on social </span><a href="https://twitter.com/ncbi"><span data-contrast="none">@NCBI</span></a><span data-contrast="none"> and </span><a href="https://public.govdelivery.com/accounts/USNLMOCPL/subscriber/new?topic_id=USNLMOCPL_52"><span data-contrast="none">join our mailing list</span></a><span data-contrast="none"> to keep up to date with dbGaP and other NCBI news.</span><span data-ccp-props='{"134233117":true,"134233118":true,"201341983":0,"335557856":16777215,"335559739":160,"335559740":240}'> </span></p>
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