82 lines
51 KiB
HTML
82 lines
51 KiB
HTML
<!DOCTYPE html>
|
||
<html amp lang="en-US" data-amp-auto-lightbox-disable transformed="self;v=1" i-amphtml-layout="" i-amphtml-no-boilerplate="">
|
||
<head><meta charset="utf-8"><meta name="viewport" content="width=device-width,minimum-scale=1"><link rel="preconnect" href="https://cdn.ampproject.org"><style amp-runtime="" i-amphtml-version="012502032353000">html{overflow-x:hidden!important}html.i-amphtml-fie{height:100%!important;width:100%!important}html:not([amp4ads]),html:not([amp4ads]) body{height:auto!important}html:not([amp4ads]) body{margin:0!important}body{-webkit-text-size-adjust:100%;-moz-text-size-adjust:100%;-ms-text-size-adjust:100%;text-size-adjust:100%}html.i-amphtml-singledoc.i-amphtml-embedded{-ms-touch-action:pan-y pinch-zoom;touch-action:pan-y pinch-zoom}html.i-amphtml-fie>body,html.i-amphtml-singledoc>body{overflow:visible!important}html.i-amphtml-fie:not(.i-amphtml-inabox)>body,html.i-amphtml-singledoc:not(.i-amphtml-inabox)>body{position:relative!important}html.i-amphtml-ios-embed-legacy>body{overflow-x:hidden!important;overflow-y:auto!important;position:absolute!important}html.i-amphtml-ios-embed{overflow-y:auto!important;position:static}#i-amphtml-wrapper{overflow-x:hidden!important;overflow-y:auto!important;position:absolute!important;top:0!important;left:0!important;right:0!important;bottom:0!important;margin:0!important;display:block!important}html.i-amphtml-ios-embed.i-amphtml-ios-overscroll,html.i-amphtml-ios-embed.i-amphtml-ios-overscroll>#i-amphtml-wrapper{-webkit-overflow-scrolling:touch!important}#i-amphtml-wrapper>body{position:relative!important;border-top:1px solid transparent!important}#i-amphtml-wrapper+body{visibility:visible}#i-amphtml-wrapper+body .i-amphtml-lightbox-element,#i-amphtml-wrapper+body[i-amphtml-lightbox]{visibility:hidden}#i-amphtml-wrapper+body[i-amphtml-lightbox] .i-amphtml-lightbox-element{visibility:visible}#i-amphtml-wrapper.i-amphtml-scroll-disabled,.i-amphtml-scroll-disabled{overflow-x:hidden!important;overflow-y:hidden!important}amp-instagram{padding:54px 0px 0px!important;background-color:#fff}amp-iframe iframe{box-sizing:border-box!important}[amp-access][amp-access-hide]{display:none}[subscriptions-dialog],body:not(.i-amphtml-subs-ready) [subscriptions-action],body:not(.i-amphtml-subs-ready) [subscriptions-section]{display:none!important}amp-experiment,amp-live-list>[update]{display:none}amp-list[resizable-children]>.i-amphtml-loading-container.amp-hidden{display:none!important}amp-list [fetch-error],amp-list[load-more] [load-more-button],amp-list[load-more] [load-more-end],amp-list[load-more] [load-more-failed],amp-list[load-more] [load-more-loading]{display:none}amp-list[diffable] div[role=list]{display:block}amp-story-page,amp-story[standalone]{min-height:1px!important;display:block!important;height:100%!important;margin:0!important;padding:0!important;overflow:hidden!important;width:100%!important}amp-story[standalone]{background-color:#000!important;position:relative!important}amp-story-page{background-color:#757575}amp-story .amp-active>div,amp-story .i-amphtml-loader-background{display:none!important}amp-story-page:not(:first-of-type):not([distance]):not([active]){transform:translateY(1000vh)!important}amp-autocomplete{position:relative!important;display:inline-block!important}amp-autocomplete>input,amp-autocomplete>textarea{padding:0.5rem;border:1px solid rgba(0,0,0,.33)}.i-amphtml-autocomplete-results,amp-autocomplete>input,amp-autocomplete>textarea{font-size:1rem;line-height:1.5rem}[amp-fx^=fly-in]{visibility:hidden}amp-script[nodom],amp-script[sandboxed]{position:fixed!important;top:0!important;width:1px!important;height:1px!important;overflow:hidden!important;visibility:hidden}
|
||
/*# sourceURL=/css/ampdoc.css*/[hidden]{display:none!important}.i-amphtml-element{display:inline-block}.i-amphtml-blurry-placeholder{transition:opacity 0.3s cubic-bezier(0.0,0.0,0.2,1)!important;pointer-events:none}[layout=nodisplay]:not(.i-amphtml-element){display:none!important}.i-amphtml-layout-fixed,[layout=fixed][width][height]:not(.i-amphtml-layout-fixed){display:inline-block;position:relative}.i-amphtml-layout-responsive,[layout=responsive][width][height]:not(.i-amphtml-layout-responsive),[width][height][heights]:not([layout]):not(.i-amphtml-layout-responsive),[width][height][sizes]:not(img):not([layout]):not(.i-amphtml-layout-responsive){display:block;position:relative}.i-amphtml-layout-intrinsic,[layout=intrinsic][width][height]:not(.i-amphtml-layout-intrinsic){display:inline-block;position:relative;max-width:100%}.i-amphtml-layout-intrinsic .i-amphtml-sizer{max-width:100%}.i-amphtml-intrinsic-sizer{max-width:100%;display:block!important}.i-amphtml-layout-container,.i-amphtml-layout-fixed-height,[layout=container],[layout=fixed-height][height]:not(.i-amphtml-layout-fixed-height){display:block;position:relative}.i-amphtml-layout-fill,.i-amphtml-layout-fill.i-amphtml-notbuilt,[layout=fill]:not(.i-amphtml-layout-fill),body noscript>*{display:block;overflow:hidden!important;position:absolute;top:0;left:0;bottom:0;right:0}body noscript>*{position:absolute!important;width:100%;height:100%;z-index:2}body noscript{display:inline!important}.i-amphtml-layout-flex-item,[layout=flex-item]:not(.i-amphtml-layout-flex-item){display:block;position:relative;-ms-flex:1 1 auto;flex:1 1 auto}.i-amphtml-layout-fluid{position:relative}.i-amphtml-layout-size-defined{overflow:hidden!important}.i-amphtml-layout-awaiting-size{position:absolute!important;top:auto!important;bottom:auto!important}i-amphtml-sizer{display:block!important}@supports (aspect-ratio:1/1){i-amphtml-sizer.i-amphtml-disable-ar{display:none!important}}.i-amphtml-blurry-placeholder,.i-amphtml-fill-content{display:block;height:0;max-height:100%;max-width:100%;min-height:100%;min-width:100%;width:0;margin:auto}.i-amphtml-layout-size-defined .i-amphtml-fill-content{position:absolute;top:0;left:0;bottom:0;right:0}.i-amphtml-replaced-content,.i-amphtml-screen-reader{padding:0!important;border:none!important}.i-amphtml-screen-reader{position:fixed!important;top:0px!important;left:0px!important;width:4px!important;height:4px!important;opacity:0!important;overflow:hidden!important;margin:0!important;display:block!important;visibility:visible!important}.i-amphtml-screen-reader~.i-amphtml-screen-reader{left:8px!important}.i-amphtml-screen-reader~.i-amphtml-screen-reader~.i-amphtml-screen-reader{left:12px!important}.i-amphtml-screen-reader~.i-amphtml-screen-reader~.i-amphtml-screen-reader~.i-amphtml-screen-reader{left:16px!important}.i-amphtml-unresolved{position:relative;overflow:hidden!important}.i-amphtml-select-disabled{-webkit-user-select:none!important;-ms-user-select:none!important;user-select:none!important}.i-amphtml-notbuilt,[layout]:not(.i-amphtml-element),[width][height][heights]:not([layout]):not(.i-amphtml-element),[width][height][sizes]:not(img):not([layout]):not(.i-amphtml-element){position:relative;overflow:hidden!important;color:transparent!important}.i-amphtml-notbuilt:not(.i-amphtml-layout-container)>*,[layout]:not([layout=container]):not(.i-amphtml-element)>*,[width][height][heights]:not([layout]):not(.i-amphtml-element)>*,[width][height][sizes]:not([layout]):not(.i-amphtml-element)>*{display:none}amp-img:not(.i-amphtml-element)[i-amphtml-ssr]>img.i-amphtml-fill-content{display:block}.i-amphtml-notbuilt:not(.i-amphtml-layout-container),[layout]:not([layout=container]):not(.i-amphtml-element),[width][height][heights]:not([layout]):not(.i-amphtml-element),[width][height][sizes]:not(img):not([layout]):not(.i-amphtml-element){color:transparent!important;line-height:0!important}.i-amphtml-ghost{visibility:hidden!important}.i-amphtml-element>[placeholder],[layout]:not(.i-amphtml-element)>[placeholder],[width][height][heights]:not([layout]):not(.i-amphtml-element)>[placeholder],[width][height][sizes]:not([layout]):not(.i-amphtml-element)>[placeholder]{display:block;line-height:normal}.i-amphtml-element>[placeholder].amp-hidden,.i-amphtml-element>[placeholder].hidden{visibility:hidden}.i-amphtml-element:not(.amp-notsupported)>[fallback],.i-amphtml-layout-container>[placeholder].amp-hidden,.i-amphtml-layout-container>[placeholder].hidden{display:none}.i-amphtml-layout-size-defined>[fallback],.i-amphtml-layout-size-defined>[placeholder]{position:absolute!important;top:0!important;left:0!important;right:0!important;bottom:0!important;z-index:1}amp-img[i-amphtml-ssr]:not(.i-amphtml-element)>[placeholder]{z-index:auto}.i-amphtml-notbuilt>[placeholder]{display:block!important}.i-amphtml-hidden-by-media-query{display:none!important}.i-amphtml-element-error{background:red!important;color:#fff!important;position:relative!important}.i-amphtml-element-error:before{content:attr(error-message)}i-amp-scroll-container,i-amphtml-scroll-container{position:absolute;top:0;left:0;right:0;bottom:0;display:block}i-amp-scroll-container.amp-active,i-amphtml-scroll-container.amp-active{overflow:auto;-webkit-overflow-scrolling:touch}.i-amphtml-loading-container{display:block!important;pointer-events:none;z-index:1}.i-amphtml-notbuilt>.i-amphtml-loading-container{display:block!important}.i-amphtml-loading-container.amp-hidden{visibility:hidden}.i-amphtml-element>[overflow]{cursor:pointer;position:relative;z-index:2;visibility:hidden;display:initial;line-height:normal}.i-amphtml-layout-size-defined>[overflow]{position:absolute}.i-amphtml-element>[overflow].amp-visible{visibility:visible}template{display:none!important}.amp-border-box,.amp-border-box *,.amp-border-box :after,.amp-border-box :before{box-sizing:border-box}amp-pixel{display:none!important}amp-analytics,amp-auto-ads,amp-story-auto-ads{position:fixed!important;top:0!important;width:1px!important;height:1px!important;overflow:hidden!important;visibility:hidden}amp-story{visibility:hidden!important}html.i-amphtml-fie>amp-analytics{position:initial!important}[visible-when-invalid]:not(.visible),form [submit-error],form [submit-success],form [submitting]{display:none}amp-accordion{display:block!important}@media (min-width:1px){:where(amp-accordion>section)>:first-child{margin:0;background-color:#efefef;padding-right:20px;border:1px solid #dfdfdf}:where(amp-accordion>section)>:last-child{margin:0}}amp-accordion>section{float:none!important}amp-accordion>section>*{float:none!important;display:block!important;overflow:hidden!important;position:relative!important}amp-accordion,amp-accordion>section{margin:0}amp-accordion:not(.i-amphtml-built)>section>:last-child{display:none!important}amp-accordion:not(.i-amphtml-built)>section[expanded]>:last-child{display:block!important}
|
||
/*# sourceURL=/css/ampshared.css*/</style><meta property="og:locale" content="en_US"><meta property="og:type" content="article"><meta property="og:title" content="New version of PGAP now available! - NCBI Insights"><meta property="og:description" content="We are happy to announce a new version of the stand-alone Prokaryotic Genome Annotation Pipeline (PGAP). This version helps you interpret your results by providing an estimate of the completeness and contamination of your PGAP-annotated genome assembly using CheckM. CheckM uses the presence of a set of lineage-specific genes for the species provided or the … Continue reading New version of PGAP now available! →"><meta property="og:url" content="https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/"><meta property="og:site_name" content="NCBI Insights"><meta property="article:publisher" content="https://www.facebook.com/ncbi.nlm"><meta property="article:published_time" content="2022-10-13T14:08:47+00:00"><meta property="og:image" content="https://ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png"><meta property="og:image:width" content="1100"><meta property="og:image:height" content="575"><meta property="og:image:type" content="image/png"><meta name="author" content="NCBI Staff"><meta name="twitter:card" content="summary_large_image"><meta name="twitter:creator" content="@NCBI"><meta name="twitter:site" content="@NCBI"><meta name="twitter:label1" content="Written by"><meta name="twitter:data1" content="NCBI Staff"><meta name="twitter:label2" content="Est. reading time"><meta name="twitter:data2" content="1 minute"><meta name="robots" content="index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1"><meta name="generator" content="AMP Plugin v2.5.5; mode=reader; theme=legacy"><script async="" src="https://cdn.ampproject.org/v0.mjs" type="module" crossorigin="anonymous"></script><script async nomodule src="https://cdn.ampproject.org/v0.js" crossorigin="anonymous"></script><script src="https://cdn.ampproject.org/v0/amp-social-share-0.1.mjs" async="" custom-element="amp-social-share" type="module" crossorigin="anonymous"></script><script async nomodule src="https://cdn.ampproject.org/v0/amp-social-share-0.1.js" crossorigin="anonymous" custom-element="amp-social-share"></script><style amp-custom="">#amp-mobile-version-switcher{left:0;position:absolute;width:100%;z-index:100}#amp-mobile-version-switcher>a{background-color:#444;border:0;color:#eaeaea;display:block;font-family:-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Oxygen-Sans,Ubuntu,Cantarell,Helvetica Neue,sans-serif;font-size:16px;font-weight:600;padding:15px 0;text-align:center;-webkit-text-decoration:none;text-decoration:none}#amp-mobile-version-switcher>a:active,#amp-mobile-version-switcher>a:focus,#amp-mobile-version-switcher>a:hover{-webkit-text-decoration:underline;text-decoration:underline}:where(.wp-block-button__link){border-radius:9999px;box-shadow:none;padding:calc(.667em + 2px) calc(1.333em + 2px);text-decoration:none}:root :where(.wp-block-button .wp-block-button__link.is-style-outline),:root :where(.wp-block-button.is-style-outline>.wp-block-button__link){border:2px solid;padding:.667em 1.333em}:root :where(.wp-block-button .wp-block-button__link.is-style-outline:not(.has-text-color)),:root :where(.wp-block-button.is-style-outline>.wp-block-button__link:not(.has-text-color)){color:currentColor}:root :where(.wp-block-button .wp-block-button__link.is-style-outline:not(.has-background)),:root :where(.wp-block-button.is-style-outline>.wp-block-button__link:not(.has-background)){background-color:initial;background-image:none}:where(.wp-block-columns){margin-bottom:1.75em}:where(.wp-block-columns.has-background){padding:1.25em 2.375em}:where(.wp-block-post-comments input[type=submit]){border:none}:where(.wp-block-cover-image:not(.has-text-color)),:where(.wp-block-cover:not(.has-text-color)){color:#fff}:where(.wp-block-cover-image.is-light:not(.has-text-color)),:where(.wp-block-cover.is-light:not(.has-text-color)){color:#000}:root :where(.wp-block-cover h1:not(.has-text-color)),:root :where(.wp-block-cover h2:not(.has-text-color)),:root :where(.wp-block-cover h3:not(.has-text-color)),:root :where(.wp-block-cover h4:not(.has-text-color)),:root :where(.wp-block-cover h5:not(.has-text-color)),:root :where(.wp-block-cover h6:not(.has-text-color)),:root :where(.wp-block-cover p:not(.has-text-color)){color:inherit}:where(.wp-block-file){margin-bottom:1.5em}:where(.wp-block-file__button){border-radius:2em;display:inline-block;padding:.5em 1em}:where(.wp-block-file__button):is(a):active,:where(.wp-block-file__button):is(a):focus,:where(.wp-block-file__button):is(a):hover,:where(.wp-block-file__button):is(a):visited{box-shadow:none;color:#fff;opacity:.85;text-decoration:none}:where(.wp-block-group.wp-block-group-is-layout-constrained){position:relative}@keyframes show-content-image{0%{visibility:hidden}99%{visibility:hidden}to{visibility:visible}}@keyframes turn-on-visibility{0%{opacity:0}to{opacity:1}}@keyframes turn-off-visibility{0%{opacity:1;visibility:visible}99%{opacity:0;visibility:visible}to{opacity:0;visibility:hidden}}@keyframes lightbox-zoom-in{0%{transform:translate(calc(( -100vw + var(--wp--lightbox-scrollbar-width) ) / 2 + var(--wp--lightbox-initial-left-position)),calc(-50vh + var(--wp--lightbox-initial-top-position))) scale(var(--wp--lightbox-scale))}to{transform:translate(-50%,-50%) scale(1)}}@keyframes lightbox-zoom-out{0%{transform:translate(-50%,-50%) scale(1);visibility:visible}99%{visibility:visible}to{transform:translate(calc(( -100vw + var(--wp--lightbox-scrollbar-width) ) / 2 + var(--wp--lightbox-initial-left-position)),calc(-50vh + var(--wp--lightbox-initial-top-position))) scale(var(--wp--lightbox-scale));visibility:hidden}}:where(.wp-block-latest-comments:not([data-amp-original-style*=line-height] .wp-block-latest-comments__comment)){line-height:1.1}:where(.wp-block-latest-comments:not([data-amp-original-style*=line-height] .wp-block-latest-comments__comment-excerpt p)){line-height:1.8}:root :where(.wp-block-latest-posts.is-grid){padding:0}:root :where(.wp-block-latest-posts.wp-block-latest-posts__list){padding-left:0}:root :where(.wp-block-list.has-background){padding:1.25em 2.375em}:where(.wp-block-navigation.has-background .wp-block-navigation-item a:not(.wp-element-button)),:where(.wp-block-navigation.has-background .wp-block-navigation-submenu a:not(.wp-element-button)){padding:.5em 1em}:where(.wp-block-navigation .wp-block-navigation__submenu-container .wp-block-navigation-item a:not(.wp-element-button)),:where(.wp-block-navigation .wp-block-navigation__submenu-container .wp-block-navigation-submenu a:not(.wp-element-button)),:where(.wp-block-navigation .wp-block-navigation__submenu-container .wp-block-navigation-submenu button.wp-block-navigation-item__content),:where(.wp-block-navigation .wp-block-navigation__submenu-container .wp-block-pages-list__item button.wp-block-navigation-item__content){padding:.5em 1em}@keyframes overlay-menu__fade-in-animation{0%{opacity:0;transform:translateY(.5em)}to{opacity:1;transform:translateY(0)}}:root :where(p.has-background){padding:1.25em 2.375em}:where(p.has-text-color:not(.has-link-color)) a{color:inherit}:where(.wp-block-post-excerpt){box-sizing:border-box;margin-bottom:var(--wp--style--block-gap);margin-top:var(--wp--style--block-gap)}:where(.wp-block-preformatted.has-background){padding:1.25em 2.375em}:where(.wp-block-search__button){border:1px solid #ccc;padding:6px 10px}:where(.wp-block-search__input){font-family:inherit;font-size:inherit;font-style:inherit;font-weight:inherit;letter-spacing:inherit;line-height:inherit;text-transform:inherit}:where(.wp-block-search__button-inside .wp-block-search__inside-wrapper){border:1px solid #949494;box-sizing:border-box;padding:4px}:where(.wp-block-search__button-inside .wp-block-search__inside-wrapper) :where(.wp-block-search__button){padding:4px 8px}:root :where(.wp-block-separator.is-style-dots){height:auto;line-height:1;text-align:center}:root :where(.wp-block-separator.is-style-dots):before{color:currentColor;content:"···";font-family:serif;font-size:1.5em;letter-spacing:2em;padding-left:2em}:root :where(.wp-block-site-logo.is-style-rounded){border-radius:9999px}:root :where(.wp-block-social-links .wp-social-link a){padding:.25em}:root :where(.wp-block-social-links.is-style-logos-only .wp-social-link a){padding:0}:root :where(.wp-block-social-links.is-style-pill-shape .wp-social-link a){padding-left:.6666666667em;padding-right:.6666666667em}:root :where(.wp-block-tag-cloud.is-style-outline){display:flex;flex-wrap:wrap;gap:1ch}:root :where(.wp-block-tag-cloud.is-style-outline a){border:1px solid;margin-right:0;padding:1ch 2ch}:root :where(.wp-block-tag-cloud.is-style-outline a):not(#_#_#_#_#_#_#_#_){font-size:unset;text-decoration:none}:root :where(.wp-block-table-of-contents){box-sizing:border-box}:where(.wp-block-term-description){box-sizing:border-box;margin-bottom:var(--wp--style--block-gap);margin-top:var(--wp--style--block-gap)}:where(pre.wp-block-verse){font-family:inherit}:root{--wp--preset--font-size--normal:16px;--wp--preset--font-size--huge:42px}html :where(.has-border-color){border-style:solid}html :where([data-amp-original-style*=border-top-color]){border-top-style:solid}html :where([data-amp-original-style*=border-right-color]){border-right-style:solid}html :where([data-amp-original-style*=border-bottom-color]){border-bottom-style:solid}html :where([data-amp-original-style*=border-left-color]){border-left-style:solid}html :where([data-amp-original-style*=border-width]){border-style:solid}html :where([data-amp-original-style*=border-top-width]){border-top-style:solid}html :where([data-amp-original-style*=border-right-width]){border-right-style:solid}html :where([data-amp-original-style*=border-bottom-width]){border-bottom-style:solid}html :where([data-amp-original-style*=border-left-width]){border-left-style:solid}html :where(amp-img[class*=wp-image-]),html :where(amp-anim[class*=wp-image-]){height:auto;max-width:100%}:where(figure){margin:0 0 1em}html :where(.is-position-sticky){--wp-admin--admin-bar--position-offset:var(--wp-admin--admin-bar--height,0px)}@media screen and (max-width:600px){html :where(.is-position-sticky){--wp-admin--admin-bar--position-offset:0px}}:root :where(.wp-block-image figcaption){color:#555;font-size:13px;text-align:center}:where(.wp-block-group.has-background){padding:1.25em 2.375em}:root :where(.wp-block-template-part.has-background){margin-bottom:0;margin-top:0;padding:1.25em 2.375em}@-webkit-keyframes a{to{-webkit-transform:rotate(1turn);transform:rotate(1turn)}}@keyframes a{to{-webkit-transform:rotate(1turn);transform:rotate(1turn)}}@-webkit-keyframes b{0%{background-position:0 0}to{background-position:30px 0}}@keyframes b{0%{background-position:0 0}to{background-position:30px 0}}amp-img.amp-wp-enforced-sizes{object-fit:contain}amp-img img,amp-img noscript{image-rendering:inherit;object-fit:inherit;object-position:inherit}.amp-wp-enforced-sizes{max-width:100%;margin:0 auto}html{background:#0a5f85}body{background:#fff;color:#353535;font-family:Georgia,"Times New Roman",Times,Serif;font-weight:300;line-height:1.75}p,figure{margin:0 0 1em;padding:0}a,a:visited{color:#0a5f85}a:hover,a:active,a:focus{color:#353535}.amp-wp-meta,.amp-wp-header div,.amp-wp-title,.amp-wp-tax-category,.amp-wp-tax-tag,.amp-wp-comments-link,.amp-wp-footer p,.back-to-top{font-family:-apple-system,BlinkMacSystemFont,"Segoe UI","Roboto","Oxygen-Sans","Ubuntu","Cantarell","Helvetica Neue",sans-serif}.amp-wp-header{background-color:#0a5f85}.amp-wp-header div{color:#fff;font-size:1em;font-weight:400;margin:0 auto;max-width:calc(840px - 32px);padding:.875em 16px;position:relative}.amp-wp-header a{color:#fff;text-decoration:none}.amp-wp-header .amp-wp-site-icon{background-color:#fff;border:1px solid #fff;border-radius:50%;position:absolute;right:18px;top:10px}.amp-wp-article{color:#353535;font-weight:400;margin:1.5em auto;max-width:840px;overflow-wrap:break-word;word-wrap:break-word}.amp-wp-article-header{align-items:center;align-content:stretch;display:flex;flex-wrap:wrap;justify-content:space-between;margin:1.5em 16px 0}.amp-wp-title{color:#353535;display:block;flex:1 0 100%;font-weight:900;margin:0 0 .625em;width:100%}.amp-wp-meta{color:#696969;display:inline-block;flex:2 1 50%;font-size:.875em;line-height:1.5em;margin:0 0 1.5em;padding:0}.amp-wp-article-header .amp-wp-meta:last-of-type{text-align:right}.amp-wp-article-header .amp-wp-meta:first-of-type{text-align:left}.amp-wp-byline amp-img,.amp-wp-byline .amp-wp-author{display:inline-block;vertical-align:middle}.amp-wp-byline amp-img{border:1px solid #0a5f85;border-radius:50%;position:relative;margin-right:6px}.amp-wp-posted-on{text-align:right}.amp-wp-article-featured-image{margin:0 0 1em}.amp-wp-article-featured-image img:not(amp-img){max-width:100%;height:auto;margin:0 auto}.amp-wp-article-featured-image amp-img{margin:0 auto}.amp-wp-article-content{margin:0 16px}.amp-wp-article-content .wp-caption{max-width:100%}.amp-wp-article-content amp-img{margin:0 auto}.wp-caption{padding:0}.amp-wp-article-footer .amp-wp-meta{display:block}.amp-wp-tax-category,.amp-wp-tax-tag{color:#696969;font-size:.875em;line-height:1.5em;margin:1.5em 16px}.amp-wp-comments-link{color:#696969;font-size:.875em;line-height:1.5em;text-align:center;margin:2.25em 0 1.5em}.amp-wp-comments-link a{border-style:solid;border-color:#c2c2c2;border-width:1px 1px 2px;border-radius:4px;background-color:transparent;color:#0a5f85;cursor:pointer;display:block;font-size:14px;font-weight:600;line-height:18px;margin:0 auto;max-width:200px;padding:11px 16px;text-decoration:none;width:50%;-webkit-transition:background-color .2s ease;transition:background-color .2s ease}.amp-wp-footer{border-top:1px solid #c2c2c2;margin:calc(1.5em - 1px) 0 0}.amp-wp-footer div{margin:0 auto;max-width:calc(840px - 32px);padding:1.25em 16px 1.25em;position:relative}.amp-wp-footer h2{font-size:1em;line-height:1.375em;margin:0 0 .5em}.amp-wp-footer p{color:#696969;font-size:.8em;line-height:1.5em;margin:0 85px 0 0}.amp-wp-footer a{text-decoration:none}.back-to-top{bottom:1.275em;font-size:.8em;font-weight:600;line-height:2em;position:absolute;right:16px}@font-face{font-family:"social-logos";src:url("data:application/octet-stream;base64,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") format("woff2");font-weight:normal;font-style:normal}amp-social-share,.amp-social-share{border-radius:50%;color:#fff;-webkit-border-radius:50%;position:relative;line-height:1;width:32px;height:32px;margin:0 5px 5px 0;vertical-align:middle}amp-social-share::before,.amp-social-share::before{display:inline-block;font:normal 18px/1 "social-logos";padding:7px;position:relative;top:1px;vertical-align:top;text-align:center}.amp-social-share.print{background:#e9e9e9;font-size:0;cursor:pointer;display:inline-block;vertical-align:middle;border:none;padding:0}.amp-social-share.print::before{content:"";color:#656565}amp-social-share[type='email']{background:#e9e9e9;color:#656565}amp-social-share[type='email']::before{content:""}amp-social-share[type='tumblr']{background:#2c4762}amp-social-share[type='tumblr']::before{content:""}amp-social-share[type='facebook']{background:#0866ff}amp-social-share[type='facebook']::before{content:""}amp-social-share[type='twitter']{background:#00acee}amp-social-share[type='twitter']::before{content:""}amp-social-share[type='pinterest']{background:#ca1f27}amp-social-share[type='pinterest']::before{content:""}amp-social-share[type='telegram']{background:#08c}amp-social-share[type='telegram']::before{content:""}amp-social-share[type='linkedin']{background:#0077b5}amp-social-share[type='linkedin']::before{content:""}amp-social-share[type='pocket']{background:#ee4056}amp-social-share[type='pocket']::before{content:""}amp-social-share[type='reddit']{background:#cee3f8;color:#555}amp-social-share[type='reddit']::before{content:""}amp-social-share[type='skype']{background:#00aff0}amp-social-share[type='skype']::before{content:""}amp-social-share[type='whatsapp']{background:#43d854}amp-social-share[type='whatsapp']::before{content:""}
|
||
|
||
/*# sourceURL=amp-custom.css */</style><link rel="canonical" href="https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/"><script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"Article","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#article","isPartOf":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/"},"author":{"name":"NCBI Staff","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#/schema/person/4f41ea6a31cea38a9a1b1419c048e50b"},"headline":"New version of PGAP now available!","datePublished":"2022-10-13T14:08:47+00:00","mainEntityOfPage":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/"},"wordCount":165,"commentCount":0,"publisher":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#organization"},"image":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#primaryimage"},"thumbnailUrl":"https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?fit=1100%2C575\u0026ssl=1","keywords":["NCBI Prokaryotic Genome Annotation Pipeline (PGAP)","Protein Family Model"],"articleSection":["What's New"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#respond"]}]},{"@type":"WebPage","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/","url":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/","name":"New version of PGAP now available! - NCBI Insights","isPartOf":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#website"},"primaryImageOfPage":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#primaryimage"},"image":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#primaryimage"},"thumbnailUrl":"https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?fit=1100%2C575\u0026ssl=1","datePublished":"2022-10-13T14:08:47+00:00","breadcrumb":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#primaryimage","url":"https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?fit=1100%2C575\u0026ssl=1","contentUrl":"https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?fit=1100%2C575\u0026ssl=1","width":1100,"height":575,"caption":"Image of DNA bases in the background in red, blue and green. Text says: Now available! Prokaryotic Genome Annotation Pipeline (PGAP) Now Available"},{"@type":"BreadcrumbList","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://ncbiinsights.ncbi.nlm.nih.gov/"},{"@type":"ListItem","position":2,"name":"New version of PGAP now available!"}]},{"@type":"WebSite","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#website","url":"https://ncbiinsights.ncbi.nlm.nih.gov/","name":"National Center for Biotechnology Information","description":"News about NCBI resources and events","publisher":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://ncbiinsights.ncbi.nlm.nih.gov/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#organization","name":"National Center for Biotechnology Information","alternateName":"NCBI","url":"https://ncbiinsights.ncbi.nlm.nih.gov/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#/schema/logo/image/","url":"https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2023/03/nih-nlm-ncbi-two-color.png?fit=6374%2C760\u0026ssl=1","contentUrl":"https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2023/03/nih-nlm-ncbi-two-color.png?fit=6374%2C760\u0026ssl=1","width":6374,"height":760,"caption":"National Center for Biotechnology Information"},"image":{"@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#/schema/logo/image/"},"sameAs":["https://www.facebook.com/ncbi.nlm","https://x.com/NCBI","https://www.linkedin.com/company/ncbinlm/"]},{"@type":"Person","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#/schema/person/4f41ea6a31cea38a9a1b1419c048e50b","name":"NCBI Staff","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https://ncbiinsights.ncbi.nlm.nih.gov/#/schema/person/image/","url":"https://secure.gravatar.com/avatar/f706d65e16bb6bb171b72b4b26f66276?s=96\u0026d=identicon\u0026r=g","contentUrl":"https://secure.gravatar.com/avatar/f706d65e16bb6bb171b72b4b26f66276?s=96\u0026d=identicon\u0026r=g","caption":"NCBI Staff"},"description":"The National Center for Biotechnology Information (NCBI), a division of the U.S. National Library of Medicine, provides access to scientific and biomedical databases, software tools for analyzing molecular data, and performs research in computational biology.","sameAs":["http://ncbiinsights.wordpress.com"],"url":"https://ncbiinsights.ncbi.nlm.nih.gov/author/ncbiinsights/"}]}</script><title>New version of PGAP now available! - NCBI Insights</title></head>
|
||
|
||
<body class="">
|
||
|
||
<header id="top" class="amp-wp-header">
|
||
<div>
|
||
<a href="https://ncbiinsights.ncbi.nlm.nih.gov/">
|
||
<amp-img src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2021/05/nlm_favicon.png?fit=32%2C32&ssl=1" width="32" height="32" class="amp-wp-site-icon amp-wp-enforced-sizes i-amphtml-layout-intrinsic i-amphtml-layout-size-defined" data-hero-candidate="" alt="Site icon" layout="intrinsic" data-hero i-amphtml-ssr i-amphtml-layout="intrinsic"><i-amphtml-sizer slot="i-amphtml-svc" class="i-amphtml-sizer"><img alt="" aria-hidden="true" class="i-amphtml-intrinsic-sizer" role="presentation" src="data:image/svg+xml;base64,PHN2ZyBoZWlnaHQ9IjMyIiB3aWR0aD0iMzIiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyIgdmVyc2lvbj0iMS4xIi8+"></i-amphtml-sizer><img class="i-amphtml-fill-content i-amphtml-replaced-content" decoding="async" alt="Site icon" src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2021/05/nlm_favicon.png?fit=32%2C32&ssl=1"></amp-img>
|
||
<span class="amp-site-title">
|
||
NCBI Insights </span>
|
||
</a>
|
||
</div>
|
||
</header>
|
||
|
||
<article class="amp-wp-article">
|
||
<header class="amp-wp-article-header">
|
||
<h1 class="amp-wp-title">New version of PGAP now available!</h1>
|
||
<div class="amp-wp-meta amp-wp-byline">
|
||
<amp-img src="https://secure.gravatar.com/avatar/f706d65e16bb6bb171b72b4b26f66276?s=72&d=identicon&r=g" srcset="
|
||
https://secure.gravatar.com/avatar/f706d65e16bb6bb171b72b4b26f66276?s=24&d=identicon&r=g 1x,
|
||
https://secure.gravatar.com/avatar/f706d65e16bb6bb171b72b4b26f66276?s=48&d=identicon&r=g 2x,
|
||
https://secure.gravatar.com/avatar/f706d65e16bb6bb171b72b4b26f66276?s=72&d=identicon&r=g 3x
|
||
" alt="NCBI Staff" width="24" height="24" layout="fixed" class="i-amphtml-layout-fixed i-amphtml-layout-size-defined" style="width:24px;height:24px" i-amphtml-layout="fixed"></amp-img>
|
||
<span class="amp-wp-author author vcard">NCBI Staff</span>
|
||
</div>
|
||
<div class="amp-wp-meta amp-wp-posted-on">
|
||
<time datetime="2022-10-13T14:08:47+00:00">
|
||
2 years ago </time>
|
||
</div>
|
||
</header>
|
||
|
||
<figure class="amp-wp-article-featured-image wp-caption">
|
||
<amp-img width="1024" height="535" src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?fit=1024%2C535&ssl=1" class="attachment-large size-large wp-post-image amp-wp-enforced-sizes i-amphtml-layout-intrinsic i-amphtml-layout-size-defined" alt="Image of DNA bases in the background in red, blue and green. Text says: Now available! Prokaryotic Genome Annotation Pipeline (PGAP) Now Available" srcset="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?w=1100&ssl=1 1100w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=300%2C157&ssl=1 300w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=1024%2C535&ssl=1 1024w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=150%2C78&ssl=1 150w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=768%2C401&ssl=1 768w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=270%2C141&ssl=1 270w" sizes="auto, (max-width: 1024px) 100vw, 1024px" data-hero-candidate="" layout="intrinsic" disable-inline-width="" data-hero i-amphtml-ssr i-amphtml-layout="intrinsic"><i-amphtml-sizer slot="i-amphtml-svc" class="i-amphtml-sizer"><img alt="" aria-hidden="true" class="i-amphtml-intrinsic-sizer" role="presentation" src="data:image/svg+xml;base64,PHN2ZyBoZWlnaHQ9IjUzNSIgd2lkdGg9IjEwMjQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyIgdmVyc2lvbj0iMS4xIi8+"></i-amphtml-sizer><img class="i-amphtml-fill-content i-amphtml-replaced-content" decoding="async" loading="lazy" alt="Image of DNA bases in the background in red, blue and green. Text says: Now available! Prokaryotic Genome Annotation Pipeline (PGAP) Now Available" src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?fit=1024%2C535&ssl=1" srcset="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?w=1100&ssl=1 1100w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=300%2C157&ssl=1 300w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=1024%2C535&ssl=1 1024w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=150%2C78&ssl=1 150w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=768%2C401&ssl=1 768w, https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2022/10/PGAP_Blog-1-e1665668789518.png?resize=270%2C141&ssl=1 270w" sizes="auto, (max-width: 1024px) 100vw, 1024px"></amp-img> </figure>
|
||
|
||
<div class="amp-wp-article-content">
|
||
<p>We are happy to announce a new version of the stand-alone <a href="https://github.com/ncbi/pgap/releases/tag/2022-10-03.build6384">Prokaryotic Genome Annotation Pipeline (PGAP)</a>. This version helps you interpret your results by providing an estimate of the completeness and contamination of your PGAP-annotated genome assembly using <a href="https://pubmed.ncbi.nlm.nih.gov/25977477/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=pgap-20221013">CheckM</a>.</p>
|
||
<p>CheckM uses the presence of a set of lineage-specific genes for the species provided or the species returned by the taxonomy check (–taxcheck, –auto-correct-tax). The higher the completeness and the lower the contamination, the better the assembly is! If contamination is a concern, please try <a href="https://ncbiinsights.ncbi.nlm.nih.gov/2022/07/28/fcs-beta-tool/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=pgap-20221013">FCS-GX</a>, a highly sensitive tool for detecting foreign contaminants in prokaryotic and eukaryotic genome assemblies.</p>
|
||
<p>This new release also contains code changes that improve prediction of some long genes, especially in low complexity regions. And, as with every release, PGAP incorporates incremental improvements from expert curators of the <a href="https://www.ncbi.nlm.nih.gov/protfam?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=pgap-20221013">Protein Family Model</a> collection that increase the precision of PGAP’s structural and functional annotation.</p>
|
||
<p>Please try this new version and <a href="https://github.com/ncbi/pgap">share your experience</a> with us!</p>
|
||
<p> </p>
|
||
<div class="sharedaddy sd-sharing-enabled"><div class="robots-nocontent sd-block sd-social sd-social-icon-text sd-sharing"><h3 class="sd-title">Share this post:</h3><div class="sd-content"><amp-social-share type="twitter" height="32px" width="32px" aria-label="Click to share on Twitter" title="Click to share on Twitter" class="i-amphtml-layout-fixed i-amphtml-layout-size-defined" style="width:32px;height:32px" i-amphtml-layout="fixed"></amp-social-share><amp-social-share type="facebook" height="32px" width="32px" aria-label="Click to share on Facebook" title="Click to share on Facebook" data-param-app_id="249643311490" class="i-amphtml-layout-fixed i-amphtml-layout-size-defined" style="width:32px;height:32px" i-amphtml-layout="fixed"></amp-social-share><button class="amp-social-share print" on="tap:AMP.print">Print</button><amp-social-share type="email" height="32px" width="32px" aria-label="Click to share on Email" title="Click to share on Email" data-target="_self" class="i-amphtml-layout-fixed i-amphtml-layout-size-defined" style="width:32px;height:32px" i-amphtml-layout="fixed"></amp-social-share></div></div></div> </div>
|
||
|
||
<footer class="amp-wp-article-footer">
|
||
<div class="amp-wp-meta amp-wp-tax-category">
|
||
Categories: <a href="https://ncbiinsights.ncbi.nlm.nih.gov/category/whats-new/" rel="category tag">What's New</a> </div>
|
||
|
||
<div class="amp-wp-meta amp-wp-tax-tag">
|
||
Tags: <a href="https://ncbiinsights.ncbi.nlm.nih.gov/tag/pgap/" rel="tag">NCBI Prokaryotic Genome Annotation Pipeline (PGAP)</a>, <a href="https://ncbiinsights.ncbi.nlm.nih.gov/tag/protein-family-model/" rel="tag">Protein Family Model</a> </div>
|
||
<div class="amp-wp-meta amp-wp-comments-link">
|
||
<a href="https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/#respond">
|
||
Leave a Comment </a>
|
||
</div>
|
||
</footer>
|
||
</article>
|
||
|
||
<footer class="amp-wp-footer">
|
||
<div>
|
||
<h2>NCBI Insights</h2>
|
||
<a href="#top" class="back-to-top">Back to top</a>
|
||
</div>
|
||
</footer>
|
||
|
||
|
||
<amp-pixel src="https://pixel.wp.com/g.gif?v=ext&blog=42777678&post=9753&tz=-5&srv=ncbiinsights.ncbi.nlm.nih.gov&hp=atomic&ac=2&amp=1&host=ncbiinsights.ncbi.nlm.nih.gov&rand=RANDOM&ref=DOCUMENT_REFERRER" class="i-amphtml-layout-fixed i-amphtml-layout-size-defined" style="width:1px;height:1px" i-amphtml-layout="fixed"></amp-pixel> <div id="amp-mobile-version-switcher">
|
||
<a rel="nofollow" href="https://ncbiinsights.ncbi.nlm.nih.gov/2022/10/13/new-pgap-available/?noamp=mobile">
|
||
Exit mobile version </a>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</body></html>
|
||
<!--
|
||
generated in 0.401 seconds
|
||
53298 bytes batcached for 300 seconds
|
||
-->
|