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<span>Amylase Test</span>
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<h1>Amylase Test</h1>
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<section><div class="mp-content"><h2>What is an amylase test?</h2>
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<p>An amylase test measures the amount of amylase in your blood or urine (pee). Amylase is an enzyme, a protein that speeds up chemical reactions in your body. Amylase helps you digest <a data-tid="3670" href="https://medlineplus.gov/carbohydrates.html">carbohydrates</a>. Most of the amylase in your body is made by your pancreas and salivary (spit) glands.</p>
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<p>It's normal to have a small amount of amylase in your blood and urine. But having too much amylase may be a sign of a <a data-tid="110" href="https://medlineplus.gov/pancreaticdiseases.html">disorder of the pancreas</a> or <a data-tid="388" href="https://medlineplus.gov/salivaryglanddisorders.html">salivary glands</a> or another medical condition.</p>
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<p>Other names: Amy test, serum amylase, urine amylase</p></div>
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</section>
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<section><div class="mp-content"><h2>What is it used for?</h2>
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<p>Tests for amylase in blood or urine are mainly used to diagnose problems with your pancreas, including <a data-tid="5876" href="https://medlineplus.gov/pancreatitis.html">pancreatitis</a>, which is inflammation of the pancreas. The test is also used to monitor chronic (long-term) pancreatitis.</p>
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<p>Changes in amylase levels show up in blood before urine, so an amylase urine test may be done with or after an amylase blood test.</p>
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<p>One or both types of amylase test may also be used to help diagnose or monitor treatment for other disorders that may affect amylase levels, such as salivary gland disorders and certain digestive conditions.</p></div>
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</section>
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<section><div class="mp-content"><h2>Why do I need an amylase test?</h2>
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<p>Your health care provider may order an amylase blood and/or urine test if you have symptoms of a pancreatic disorder. Symptoms may begin suddenly or slowly. They may include:</p>
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<ul>
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<li><a data-tid="3061" href="https://medlineplus.gov/abdominalpain.html">Pain in your upper abdomen</a> (belly) that may spread to your back, get worse after eating, or last for several days</li>
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<li>Loss of appetite</li>
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<li><a data-tid="489" href="https://medlineplus.gov/nauseaandvomiting.html">Nausea and vomiting</a></li>
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<li><a data-tid="511" href="https://medlineplus.gov/fever.html">Fever</a></li>
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<li>Fast heartbeat</li>
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<li><a data-tid="4452" href="https://medlineplus.gov/jaundice.html">Jaundice</a> (a condition that causes your skin and eyes to turn yellow)</li>
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<li>Greasy, foul-smelling stool (poop)</li>
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</ul>
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<p>Your provider may also order an amylase test to monitor an existing condition that affects your pancreas, including:</p>
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<ul>
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<li>Chronic pancreatitis</li>
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<li><a data-tid="469" href="https://medlineplus.gov/pancreaticcancer.html">Pancreatic cancer</a></li>
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<li><a data-tid="237" href="https://medlineplus.gov/eatingdisorders.html">Eating disorders</a></li>
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<li><a data-tid="203" href="https://medlineplus.gov/cysticfibrosis.html">Cystic fibrosis</a></li>
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<li><a data-tid="120" href="https://medlineplus.gov/alcoholusedisorderaud.html">Alcohol use disorder</a> (AUD)</li>
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<li>Recovery after having <a data-tid="4643" href="https://medlineplus.gov/gallstones.html">gallstones</a> removed because of a gallbladder attack</li>
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</ul></div>
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</section>
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<section><div class="mp-content"><h2>What happens during an amylase test?</h2>
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<p>For an amylase blood test, a health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.</p>
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<p>For an amylase urine test, you will need to give a urine sample for the test. A health care professional may give you a cleansing wipe, a small container, and instructions for how to use the "clean catch" method to collect your urine sample. It's important to follow these instructions so that germs from your skin don't get into the sample:</p>
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<ol>
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<li>Wash your hands with soap and water and dry them.</li>
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<li>Open the container without touching the inside.</li>
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<li>Clean your genital area with the cleansing wipe:
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<ul>
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<li>For a penis, wipe the entire head (end) of the penis. If you have a foreskin, pull it back first.</li>
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<li>For a vagina, separate the labia (the folds of skin around the vagina) and wipe the inner sides from front to back.</li>
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</ul>
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</li>
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<li>Urinate into the toilet for a few seconds and then stop the flow. Start urinating again, this time into the container. Don't let the container touch your body.</li>
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<li>Collect at least an ounce or two of urine into the container. The container should have markings to show how much urine is needed.</li>
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<li>Finish urinating into the toilet.</li>
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<li>Put the cap on the container and return it as instructed.</li>
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</ol>
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<p>If you have <a data-tid="1226" href="https://medlineplus.gov/hemorrhoids.html">hemorrhoids</a> that bleed or are having your <a data-tid="325" href="https://medlineplus.gov/menstruation.html">menstrual period</a>, tell your provider before your test.</p>
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<p>Your provider may request that you collect all your urine during a 24-hour period. That's because the amount of amylase in urine can vary throughout the day. Collecting urine from an entire day can provide more accurate information about your amylase levels. For a 24-hour urine test, you will be given a container and specific instructions on how to collect your sample at home. Be sure to follow all instructions carefully.</p>
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<p>In certain cases, your provider may order a test for amylase in peritoneal fluid. This fluid is found between the layers of tissue that line the inside of your abdomen (belly) and cover most of your organs. To get a sample, a health care professional will numb your skin and use a needle and tubing to draw some fluid into a container.</p></div>
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</section>
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<section><div class="mp-content"><h2>Will I need to do anything to prepare for the test?</h2>
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<p>You should not drink alcohol for 24 hours before having an amylase blood or urine test. If you are having a blood test, your provider may also tell you to <a data-pid="858" href="https://medlineplus.gov/lab-tests/fasting-for-a-blood-test/">fast</a> (not eat or drink) for two hours before the test. Your provider will let you know if there are any special instructions to follow.</p>
|
||
<p>Be sure to tell your provider about any prescription or over-the-counter medicines you are taking because they may affect your test results. But don't stop taking any medicines unless your provider tells you to.</p></div>
|
||
</section>
|
||
|
||
<section><div class="mp-content"><h2>Are there any risks to the test?</h2>
|
||
<p>There is very little risk to having a blood test. During a blood test, you may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.</p>
|
||
<p>There is no known risk to having a urine test.</p>
|
||
<p>If you have a peritoneal fluid test, you may feel a little dizzy or lightheaded after the procedure. There is a small risk that the needle could damage your bowel or bladder, which may lead to bleeding or infection.</p></div>
|
||
</section>
|
||
|
||
<section><div class="mp-content"><h2>What do the results mean?</h2>
|
||
<p><strong>High levels of amylase in blood or urine</strong> may be a sign of:</p>
|
||
<ul>
|
||
<li>Acute (sudden) pancreatitis</li>
|
||
<li>A blockage in a duct (small tube) in the pancreas</li>
|
||
<li>Cancer or a benign (not cancerous) tumor of the pancreas</li>
|
||
</ul>
|
||
<p><strong>High levels of amylase in peritoneal fluid</strong> may be a sign of:</p>
|
||
<ul>
|
||
<li>Acute (sudden) pancreatitis</li>
|
||
<li>A <a data-tid="5275" href="https://medlineplus.gov/intestinalobstruction.html">blocked intestine</a></li>
|
||
<li>Lack of blood flow to the intestines</li>
|
||
</ul>
|
||
<p><strong>Low levels of amylase in blood or urine</strong> are uncommon, but may be a sign of:</p>
|
||
<ul>
|
||
<li>Chronic pancreatitis causing permanent damage to the cells that make amylase</li>
|
||
<li><a data-tid="91" href="https://medlineplus.gov/kidneydiseases.html">Kidney disease</a></li>
|
||
<li>Cystic fibrosis</li>
|
||
<li><a data-tid="310" href="https://medlineplus.gov/liverdiseases.html">Liver disease</a></li>
|
||
<li>Pre-eclampsia (a type of <a data-tid="1508" href="https://medlineplus.gov/highbloodpressureinpregnancy.html">high blood pressure in pregnancy</a>)</li>
|
||
</ul>
|
||
<p>To learn more about your results, talk with your provider.</p>
|
||
<p>Learn more about <a data-pid="806" href="https://medlineplus.gov/lab-tests/how-to-understand-your-lab-results/">laboratory tests, reference ranges, and understanding results</a>.</p></div>
|
||
</section>
|
||
|
||
<section><div class="mp-content"><h2>Is there anything else I need to know about an amylase test?</h2>
|
||
<p>If your provider suspects you have pancreatitis, they may order a <a data-pid="814" href="https://medlineplus.gov/lab-tests/lipase-tests/">lipase blood test</a>, along with an amylase blood test. Lipase is another enzyme produced by the pancreas. Lipase tests are considered to be more accurate for diagnosing pancreatitis, especially when pancreatitis is caused by alcohol use disorder.</p></div>
|
||
</section>
|
||
|
||
<section><div class="mp-refs mp-content"><h2>References</h2>
|
||
<ol>
|
||
<li>Akinfemiwa O, Muniraj T. Amylase. [Updated 2023 Nov 12; cited 2024 Nov 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: <a href="https://www.ncbi.nlm.nih.gov/books/NBK557738/" target="bibliowin">https://www.ncbi.nlm.nih.gov/books/NBK557738/</a></li>
|
||
<li>Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2024.Amylase Test; [reviewed 2022 Feb 2; cited 2024 Nov 14]; [about 8 screens]. Available from: <a href="https://my.clevelandclinic.org/health/diagnostics/22386-amylase-test" target="bibliowin">https://my.clevelandclinic.org/health/diagnostics/22386-amylase-test</a></li>
|
||
<li>Cleveland Clinic: Health Library: Diagnostics & Testing [Internet]. Cleveland (OH): Cleveland Clinic; c2024. Blood Tests; [reviewed 2022 Dec 06; cited 2024 Nov 14]; [about 16 screens]. Available from: <a href="https://my.clevelandclinic.org/health/diagnostics/24508-blood-tests" target="bibliowin">https://my.clevelandclinic.org/health/diagnostics/24508-blood-tests</a></li>
|
||
<li>Johns Hopkins Medicine [Internet]. Johns Hopkins Medicine; c2024. Health Library: Acute Pancreatitis [cited 2024 Nov 14]; [about 4 screens]. Available from: <a href="https://www.hopkinsmedicine.org/health/conditions-and-diseases/acute-pancreatitis" target="bibliowin">https://www.hopkinsmedicine.org/health/conditions-and-diseases/acute-pancreatitis</a></li>
|
||
<li>Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998-2024. Urinalysis; 2023 Oct 24 [cited 2024 Nov 14]; [about 6 screens]. Available from: <a href="https://www.mayoclinic.org/tests-procedures/urinalysis/about/pac-20384907" target="bibliowin">https://www.mayoclinic.org/tests-procedures/urinalysis/about/pac-20384907</a></li>
|
||
<li>Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Merck & Co., Inc.; c2024. Urinalysis and Urine Culture; [modified 2024 Jan; cited 2024 Nov 14]; [about 3 screens]. Available from: <a href="https://www.merckmanuals.com/home/kidney-and-urinary-tract-disorders/diagnosis-of-kidney-and-urinary-tract-disorders/urinalysis-and-urine-culture" target="bibliowin">https://www.merckmanuals.com/home/kidney-and-urinary-tract-disorders/diagnosis-of-kidney-and-urinary-tract-disorders/urinalysis-and-urine-culture</a></li>
|
||
<li>National Cancer Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; NCI Dictionary of Cancer Terms: amylase [cited 2024 Nov 14]; [about 1 screen]. Available from: <a href="https://www.cancer.gov/publications/dictionaries/cancer-terms/def/amylase" target="bibliowin">https://www.cancer.gov/publications/dictionaries/cancer-terms/def/amylase</a></li>
|
||
<li>National Cancer Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; NCI Dictionary of Cancer Terms: enzyme [cited 2024 Nov 14]; [about 1 screen]. Available from: <a href="https://www.cancer.gov/search/results?swKeyword=enzyme" target="bibliowin">https://www.cancer.gov/search/results?swKeyword=enzyme</a></li>
|
||
<li>National Cancer Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; NCI Dictionary of Cancer Terms: peritoneum [cited 2024 Nov 14]; [about 1 screens]. Available from: <a href="https://www.cancer.gov/publications/dictionaries/cancer-terms/def/peritoneum" target="bibliowin">https://www.cancer.gov/publications/dictionaries/cancer-terms/def/peritoneum</a></li>
|
||
<li>National Institute of Diabetes and Digestive and Kidney Diseases [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Pancreatitis; [reviewed 2017 Nov; cited 2024 Nov 14]; [about 3 screens]. Available from: <a href="https://www.niddk.nih.gov/health-information/digestive-diseases/pancreatitis" target="bibliowin">https://www.niddk.nih.gov/health-information/digestive-diseases/pancreatitis</a></li>
|
||
<li>Nemours KidsHealth [Internet]. Jacksonville (FL): The Nemours Foundation; c1995-2024. Getting a Blood Test; [reviewed 2021 Sep; cited 2024 Nov 14]; [about 4 screens]. Available from: <a href="https://kidshealth.org/en/parents/blood-tests.html" target="bibliowin">https://kidshealth.org/en/parents/blood-tests.html</a></li>
|
||
<li>Testing.com [Internet]. Seattle (WA): OneCare Media; c2024. Amylase; [modified 2022 Dec 4; cited 2024 Nov 14]; [about 10 screens]. Available from: <a href="https://www.testing.com/tests/amylase/" target="bibliowin">https://www.testing.com/tests/amylase/</a></li>
|
||
<li>Testing.com [Internet]. Seattle (WA): OneCare Media; c2024. Lipase [modified 2022 Dec 6; cited 2024 Nov 14]; [about 9 screens]. Available from: <a href="https://www.testing.com/tests/lipase/" target="bibliowin">https://www.testing.com/tests/lipase/</a></li>
|
||
<li>University of California San Francisco [Internet]. The Regents of the University of California; c2002-2024. Clean Catch Urine Sample; [reviewed 2022 Jul 25; cited 2024 Dec 26]; [about 1 screen]. Available from: <a href="https://www.ucsfhealth.org/medical-tests/clean-catch-urine-sample" target="bibliowin">https://www.ucsfhealth.org/medical-tests/clean-catch-urine-sample</a></li>
|
||
</ol></div>
|
||
</section>
|
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<li><a href="https://medlineplus.gov/pancreatitis.html">Pancreatitis</a></li>
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<section><div class="side-section">
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<h2>Related Medical Tests</h2>
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<div class="section-body">
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<ul class="relatedmp">
|
||
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<li><a href="https://medlineplus.gov/lab-tests/chymotrypsin-in-stool/">Chymotrypsin in Stool</a></li>
|
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|
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<li><a href="https://medlineplus.gov/lab-tests/fasting-for-a-blood-test/">Fasting for a Blood Test</a></li>
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<li><a href="https://medlineplus.gov/lab-tests/how-to-cope-with-medical-test-anxiety/">How to Cope with Medical Test Anxiety</a></li>
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<li><a href="https://medlineplus.gov/lab-tests/how-to-understand-your-lab-results/">How to Understand Your Lab Results</a></li>
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|
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<li><a href="https://medlineplus.gov/lab-tests/lipase-tests/">Lipase Tests</a></li>
|
||
|
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|
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<li><a href="https://medlineplus.gov/lab-tests/stool-elastase/">Stool Elastase</a></li>
|
||
|
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|
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<li><a href="https://medlineplus.gov/lab-tests/what-you-need-to-know-about-blood-testing/">What You Need to Know About Blood Testing</a></li>
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"description": "An amylase test measures the amount of amylase in your blood or urine (pee). Amylase is an enzyme, a protein that speeds up chemical reactions in your body. Amylase helps you digest carbohydrates. Most of the amylase in your body is made by your pancreas and salivary (spit) glands. It's normal to have a small amount of amylase in your blood and urine. But having too much amylase may be a sign of a disorder of the pancreas or salivary glands or another medical condition. Other names: Amy test, serum amylase, urine amylase",
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