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</div><div><span>Nuchal translucency test</span></div></div>
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</a><h1 class="with-also" itemprop="name">Nuchal translucency test</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>The nuchal translucency test measures the nuchal fold thickness. This is an area of tissue at the back of an unborn baby's neck. Measuring this thickness helps assess the risk for <a test="test" href="./000997.htm">Down syndrome</a> and other genetic problems in the baby. </p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>Your health care provider uses <a test="test" href="./003778.htm">abdominal ultrasound</a> or a <a test="test" href="./003779.htm">vaginal ultrasound</a> to measure the nuchal fold. All unborn babies have some fluid at the back of their neck. In a baby with Down syndrome or other genetic disorders, there is more fluid than normal. This makes the space look thicker.</p><p>A blood test of the mother is also done. Together, these two tests will tell if the baby could have Down syndrome or another genetic disorder.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How to Prepare for the Test</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Having a full bladder will give the best abdominal ultrasound picture. You may be asked to drink 2 to 3 glasses of liquid an hour before the test. DO NOT urinate before your ultrasound.</p><p>If a vaginal ultrasound is performed, your bladder should be empty.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test will Feel</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>You may have some discomfort from pressure on your bladder during the ultrasound. The gel used during the test may feel slightly cold and wet. You will not feel the ultrasound waves. </p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Why the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>Your provider may advise this test to screen your baby for Down syndrome. Many pregnant women decide to have this test.</p><p>Nuchal translucency is usually done between the 11th and 14th week of pregnancy. It can be done earlier in pregnancy than <a test="test" href="./003921.htm">amniocentesis</a>. Amniocentesis is another test that checks for birth defects.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Normal Results</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>A normal amount of fluid in the back of the neck during ultrasound means it is very unlikely your baby has Down syndrome or another genetic disorder.</p><p>Nuchal translucency measurement increases with gestational age. This is the period between conception and birth. The higher the measurement compared to babies the same gestational age, the higher the risk is for certain genetic disorders.</p><p>A measurement of up to 3 mm is considered a low risk for genetic disorders. However, different clinics may use slightly different numbers based on their experience.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>What Abnormal Results Mean</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>More fluid than normal in the back of the neck means there is a higher risk for Down syndrome, trisomy 18, trisomy 13, Turner syndrome, or congenital heart disease. But it does not tell for certain that the baby has Down syndrome or another genetic disorder. A diagnostic test is required to find out if a serious genetic disorder is present.</p><p>The nuchal translucency test is a screening test. It does not screen for genetic problems in babies. It is helpful in deciding who may need further testing. An abnormal result would then require follow up of a diagnostic test such as an amniocentesis or non-invasive prenatal test (NIPT).</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Risks</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>There are no known risks from ultrasound. </p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Nuchal translucency screening; NT; Nuchal fold test; Nuchal fold scan; Prenatal genetic screening; Down syndrome - nuchal translucency</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>American College of Obstetricians and Gynecologists website. NIPT summary of recommendations. <a href="https://www.acog.org/advocacy/policy-priorities/non-invasive-prenatal-testing/current-acog-guidance" target="_blank">www.acog.org/advocacy/policy-priorities/non-invasive-prenatal-testing/current-acog-guidance</a>. Accessed June 7, 2023.</p><p>Driscoll DA, Simpson JL. Genetic screening and diagnosis. In: Landon MB, Galan HL, Jauniaux ERM, et al, eds. <em>Gabbe's Obstetrics: Normal and Problem Pregnancies. </em>8th ed. Philadelphia, PA: Elsevier; 2021:chap 10.</p><p>Dugoff L, Wapner RJ. Prenatal diagnosis of congenital disorders. In: Lockwood CJ, Copel JA, Dugoff L, et al, eds. <em>Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice.</em> 9th ed. Philadelphia, PA: Elsevier; 2023:chap 30. </p><p>Walsh JM, D'Alton ME. Nuchal translucency. In: Copel JA, D'Alton ME, Feltovich H, et al, eds. <em>Obstetric Imaging: Fetal Diagnosis and Care.</em> 2nd ed. Philadelphia, PA: Elsevier; 2018:chap 45.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 6/5/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: John D. Jacobson, MD, Professor Emeritus, Department of Obstetrics and Gynecology, Loma Linda University School of Medicine, Loma Linda, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
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