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</div><div><span>Parathyroid hormone (PTH) blood test</span></div></div>
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</a><h1 class="with-also" itemprop="name">Parathyroid hormone (PTH) blood test</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>The PTH test measures the level of parathyroid hormone in the blood.</p><p>PTH stands for parathyroid hormone. It is a protein hormone released by the parathyroid gland. </p><p>A laboratory test can be done to measure the amount of PTH in your blood.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>A <a test="test" href="./003423.htm">blood sample</a> is needed.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How to Prepare for the Test</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Ask your health care provider if you should stop eating or drinking for some period of time before the test. Most often, you will not need to fast or stop drinking.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test will Feel</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or slight bruising. This soon goes away.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Why the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>PTH is released by the parathyroid glands. The 4 small parathyroid glands are located in the neck, near or attached to the back side of the thyroid gland. The thyroid gland is located in the neck, just above where your collarbones meet in the middle.</p><p>PTH controls calcium, phosphorus, and vitamin D levels in the blood. It is important for regulating bone growth. Your provider may order this test if: </p><ul><li>You have a <a test="test" href="./000365.htm">high calcium level</a> or <a test="test" href="./000307.htm">low phosphorus</a> level in your blood.</li><li>You have severe <a test="test" href="./000360.htm">osteoporosis</a> that cannot be explained or does not respond to treatment.</li><li>You have kidney disease.</li></ul><p>To help understand whether your PTH is normal, your provider will measure your <a test="test" href="./003477.htm">blood calcium</a> at the same time.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Normal Results</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>Normal values are 10 to 55 picograms per milliliter (pg/mL). </p><p>Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different specimens. Talk to your provider about the meaning of your specific test results. Try to go back to the same lab each time you need to have your PTH level tested so your provider can reliably compare your results over time. </p><p>A PTH value in the normal range can still be inappropriate when serum calcium levels are high. Talk to your provider about what your result means.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>What Abnormal Results Mean</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>A higher-than-normal level may occur with:</p><ul><li>Disorders that increase phosphate or phosphorous levels in the blood, such as <a test="test" href="./000471.htm">long-term (chronic) kidney disease</a></li><li>Failure of the body to respond to PTH (pseudohypoparathyroidism)</li><li>Lack of calcium, which may be due to not eating enough calcium, not absorbing calcium in the gut, or losing too much calcium in your urine</li><li>Pregnancy or breastfeeding (uncommon)</li><li>Swelling or tumors (adenomas) in the parathyroid glands, called primary <a test="test" href="./001215.htm">hyperparathyroidism</a></li><li>Vitamin D disorders, including not enough sunlight in older adults and problems absorbing, breaking down, and using vitamin D in the body </li></ul><p>A lower-than-normal level may occur with:</p><ul><li>Accidental removal of parathyroid glands during thyroid surgery</li><li>Autoimmune destruction of the parathyroid gland</li><li>Cancers that start in another part of the body (such as the breast, lungs, or colon) and spread to the bone (releasing calcium into the blood stream)</li><li><a test="test" href="./000332.htm">Excess calcium intake over a long period of time</a>, usually from excess calcium supplements or certain antacids, that contain calcium carbonate or sodium bicarbonate (baking soda)</li><li>Parathyroid glands that do not produce enough PTH (<a test="test" href="./000385.htm">hypoparathyroidism</a>)</li><li><a test="test" href="./000315.htm">Low levels of magnesium in the blood</a></li><li>Radiation to the parathyroid glands</li><li><a test="test" href="./000076.htm">Sarcoidosis</a> and tuberculosis (usually when these conditions lead to a high serum calcium level)</li><li><a test="test" href="./001594.htm">Excess vitamin D intake</a></li></ul><p>Other conditions for which the test may be ordered include:</p><ul><li><a test="test" href="./000398.htm">Multiple endocrine neoplasia (MEN) I</a></li><li><a test="test" href="./000399.htm">Multiple endocrine neoplasia (MEN) II</a></li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Risks</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.</p><p>Other risks associated with having blood drawn are slight, but may include:</p><ul><li>Excessive bleeding</li><li>Multiple punctures to locate veins</li><li>Fainting or feeling lightheaded</li><li>Hematoma (blood accumulating under the skin)</li><li>Infection (a slight risk any time the skin is broken) </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Parathormone; Parathormone (PTH) intact molecule; Intact PTH; Hyperparathyroidism - PTH blood test; Hypoparathyroidism - PTH blood test</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Bringhurst FR, Demay MB, Kronenberg HM. Hormones and disorders of mineral metabolism. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. <em>Williams Textbook of Endocrinology</em>. 14th ed. Philadelphia, PA: Elsevier; 2020:chap 29.</p><p>Klemm KM, Klein MJ, Zhang Y. Biochemical markers of bone metabolism. In: McPherson RA, Pincus MR, eds. <em>Henry's Clinical Diagnosis and Management by Laboratory Methods</em>. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 16.</p></div></div></section>
<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 10/29/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Sandeep K. Dhaliwal, MD, board-certified in Diabetes, Endocrinology, and Metabolism, Springfield, VA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
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