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</div><div><span>Glomus jugulare tumor</span></div></div>
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<article><div id="d-article"><div class="page-info"><div class="page-title"><a name="start" id="start">
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</a><h1 class="with-also" itemprop="name">Glomus jugulare tumor</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>A glomus jugulare tumor is a tumor of the part of the temporal bone in the skull that involves the middle and inner ear structures. This tumor can affect the ear, upper neck, base of the skull, and the surrounding blood vessels and nerves.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>Causes</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>A glomus jugulare tumor grows in the temporal bone of the skull, in an area called the jugular foramen. The jugular foramen is also where the jugular vein and several important nerves exit the skull.</p><p>This area contains nerve fibers, called glomus bodies. Normally, these nerves respond to changes in body temperature or blood pressure.</p><p>These tumors most often occur later in life, around age 60 or 70, but they can appear at any age. The cause of a glomus jugulare tumor is unknown. In most cases, there are no known risk factors. Glomus tumors have been associated with changes (mutations) in a gene responsible for the enzyme succinate dehydrogenase (SDHD).</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Symptoms</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Symptoms may include:</p><ul><li>Difficulty swallowing (dysphagia)</li><li>Dizziness</li><li>Hearing problems or loss</li><li>Hearing pulsations in the ear</li><li>Hoarseness</li><li>Pain</li><li>Weakness or loss of movement in the face (facial nerve palsy) </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Exams and Tests</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>Glomus jugulare tumors are diagnosed by a physical exam and imaging tests, including:</p><ul><li><a test="test" href="./003799.htm">Cerebral angiography</a></li><li><a test="test" href="./003330.htm">CT scan</a></li><li><a test="test" href="./003335.htm">MRI scan</a></li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Treatment</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>Glomus jugulare tumors are rarely cancerous and do not tend to spread to other parts of the body. However, treatment may be needed to relieve symptoms. The main treatment is surgery. Surgery is complex and is most often done by a neurosurgeon, head and neck surgeon, and ear surgeon (neurotologist).</p><p>In some cases, a procedure called embolization is performed before surgery to prevent the tumor from bleeding too much during surgery.</p><p>After surgery, radiation therapy may be used to treat any part of the tumor that could not be removed completely.</p><p>Some glomus tumors can be treated with <a test="test" href="./007274.htm">stereotactic radiosurgery</a>.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Outlook (Prognosis)</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>People who have surgery or radiation usually do well. More than 90% of those with glomus jugulare tumors are cured.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Possible Complications</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>The most common complications are due to nerve damage, which may be caused by the tumor itself or damage during surgery. Nerve damage can lead to:</p><ul><li>Change in voice</li><li>Difficulty swallowing</li><li>Hearing loss</li><li>Paralysis of the face</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>When to Contact a Medical Professional</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>Contact your health care provider if you:</p><ul><li>Are having difficulty with hearing or swallowing</li><li>Develop pulsations in your ear</li><li>Notice a lump in your neck</li><li>Notice any problems with the muscles in your face</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Paraganglioma - glomus jugulare</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Gubbels SP, Hartl RB, Crowson MG, Jenkns HA, Marsh M. Temporal bone neoplasms and lateral cranial base surgery. In: Flint PW, Francis HW, Haughey BH, et al, eds. <em>Cummings Otolaryngology: Head and Neck Surgery. </em>7th ed. Philadelphia, PA: Elsevier; 2021:chap 178.</p><p>Rucker JC, Seay MD. Cranial neuropathies. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. <em>Bradley and Daroff's Neurology in Clinical Practice. </em>8th ed. Philadelphia, PA: Elsevier; 2022: chap 103.</p><p>Verlicchi A, Nicolato A, Valvassori, L, De Donato G, Zanotti B. Head and neck paragangliomas. In: Winn HR, ed. <em>Youmans and Winn Neurological Surgery.</em> 8th ed. Philadelphia, PA: Elsevier; 2023:chap 181.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 12/31/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Josef Shargorodsky, MD, MPH, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. </p>
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