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</div><div><span>Wolff-Parkinson-White syndrome (WPW)</span></div></div>
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</a><h1 class="with-also" itemprop="name">Wolff-Parkinson-White syndrome (WPW)</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Wolff-Parkinson-White (WPW) syndrome is a condition in which there is an extra electrical pathway in the heart that leads to periods of rapid heart rate (<a test="test" href="./003077.htm">tachycardia</a>).</p><p>WPW syndrome is one of the most common causes of fast heart rate problems in infants and children.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>Causes</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>Normally, electrical signals follow a certain pathway through the heart. This helps the heart beat regularly. This prevents the heart from having extra beats or beats happening too soon.</p><p>In people with WPW syndrome, some of the heart's electrical signals go down an extra pathway. This may cause a very rapid heart rate called supraventricular tachycardia.</p><p>Most people with WPW syndrome do not have any other heart problems. However, this condition has been linked with other cardiac conditions, such as <a test="test" href="./007321.htm">Ebstein anomaly</a>. A form of the condition also runs in families.</p><img title="Ebstein's anomaly" alt="Ebstein's anomaly" src="//medlineplus.gov/ency/images/ency/fullsize/22703.jpg" class="img-e" itemprop="image"/></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Symptoms</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>How often a rapid heart rate occurs varies depending on the person. Some people with WPW syndrome have only a few episodes of rapid heart rate. Others may have the rapid heart rate once or twice a week or more. Also, there may be no symptoms at all, so that condition is found when a heart test is done for another reason.</p><p>A person with this syndrome may have:</p><ul><li><a test="test" href="./003079.htm">Chest pain</a> or chest tightness</li><li><a test="test" href="./003093.htm">Dizziness</a></li><li>Lightheadedness</li><li><a test="test" href="./003092.htm">Fainting</a></li><li><a test="test" href="./003081.htm">Palpitations</a> (a sensation of feeling your heart beating, usually quickly or irregularly)</li><li><a test="test" href="./003075.htm">Shortness of breath</a></li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Exams and Tests</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>A physical exam done during a tachycardia episode will show a heart rate faster than 100 beats per minute. A normal heart rate is 60 to 100 beats per minute in adults, and under 150 beats per minute in newborns, infants, and small children. Blood pressure will be normal or low in most cases.</p><p>If the person is not having tachycardia at the time of the exam, the results may be normal. The condition may be diagnosed with an <a test="test" href="./003868.htm">electrocardiogram</a> (ECG) or with ambulatory ECG monitoring, such as a <a test="test" href="./003877.htm">Holter monitor</a>.</p><img title="Holter heart monitor" alt="Holter heart monitor" src="//medlineplus.gov/ency/images/ency/fullsize/8810.jpg" class="img-e" itemprop="image"/><p>A test called an <a test="test" href="./003867.htm">electrophysiologic study</a> (EPS) is done using catheters that are placed in the heart. This test may help identify the location of the extra electrical pathway.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Treatment</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>Medicines, particularly antiarrhythmic drugs such as procainamide or amiodarone, may be used to control or prevent a rapid heartbeat. </p><p>If the heart rate does not return to normal with medical treatment, health care providers may use a type of therapy called electrical <a test="test" href="./007110.htm">cardioversion</a> (shock).</p><p>The long-term treatment for WPW syndrome is very often <a test="test" href="./007368.htm">catheter ablation</a>. This procedure involves inserting a tube (catheter) into a vein through a small cut near the groin up to the heart area. When the tip reaches the heart, the small area that is causing the fast heart rate is destroyed using a special type of energy called radiofrequency or by freezing it (cryoablation). This is done as part of an electrophysiologic study (EPS).</p><p>Before ablation is considered, you may be asked to undergo an exercise stress test to help decide if you need ablation.</p><p><a test="test" href="./002950.htm">Open heart surgery</a> to burn or freeze the extra pathway may also provide a permanent cure for WPW syndrome. In most cases, this procedure is done only if you need heart surgery for other reasons.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Outlook (Prognosis)</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>Catheter ablation cures this disorder in most people. The success rate for the procedure ranges between 85% to 95%. Success rates will vary depending on the location and number of extra pathways.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Possible Complications</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>Complications may include:</p><ul><li>Complications of surgery</li><li><a test="test" href="./000158.htm">Heart failure</a></li><li>Reduced blood pressure (caused by <a test="test" href="./003077.htm">rapid heart rate</a>)</li><li>Side effects of medicines</li></ul><p>The most severe form of a rapid heartbeat is <a test="test" href="./007200.htm">ventricular fibrillation</a> (VF), which will rapidly lead to shock or death unless it is corrected. It can sometimes occur in people with WPW, particularly if they also have <a test="test" href="./000184.htm">atrial fibrillation</a> (AF), which is another type of abnormal heart rhythm. This type of rapid heartbeat requires emergency treatment and a procedure called cardioversion.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>When to Contact a Medical Professional</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>Contact your provider if: </p><ul><li>You have symptoms of WPW syndrome.</li><li>You have this disorder and symptoms get worse or do not improve with treatment.</li></ul><p>Talk to your provider about whether your family members should be screened for inherited forms of this condition.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Preexcitation syndrome; WPW; Tachycardia - Wolff-Parkinson-White syndrome; Arrhythmia - WPW; Abnormal heart rhythm - WPW; Rapid heartbeat - WPW</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Images</h2></div><div class="section-button"><button type="submit" aria-controls="section-tnails" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/22703t.jpg" alt="Ebstein's anomaly" title="Ebstein's anomaly" class="side-img"/><a href="../imagepages/19884.htm">Ebstein's anomaly</a></li>
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/18052t.jpg" alt="Conduction system of the heart" title="Conduction system of the heart" class="side-img"/><a href="../imagepages/18052.htm">Conduction system of the heart</a></li>
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</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Dalal AS, Van Hare GF. Disturbances of rate and rhythm of the heart. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. <em>Nelson Textbook of Pediatrics</em>. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 462.</p><p>Kalman JM, Sanders P. Supraventricular Tachycardias. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. <em>Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine</em>. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 65.</p><p>Zimetbaum P, Goldman L. Supraventricular ectopy and tachyarrhythmias. In: Goldman L, Cooney KA, eds. <em>Goldman-Cecil Medicine</em>. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 52.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 2/27/2024</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Thomas S. Metkus, MD, Assistant Professor of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. </p>
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